| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eleni Koutsilieri, Peter Riederer, Stefan du Plessis, Carsten Schelle. A short review on the relation between the dopamine transporter 10/10-repeat allele and ADHD: implications for HIV infection. Attention deficit and hyperactivity disorders. vol 6. issue 3. 2015-06-22. PMID:24696011. |
the dopamine transporter (dat) is a functional element of the dopaminergic synapse in the brain. |
2015-06-22 |
2023-08-13 |
human |
| Bingjie Xie, Fankai Lin, Lei Peng, Kaleem Ullah, Hanyan Wu, Hong Qing, Yulin Den. Methylglyoxal increases dopamine level and leads to oxidative stress in SH-SY5Y cells. Acta biochimica et biophysica Sinica. vol 46. issue 11. 2015-06-22. PMID:25274329. |
the expressions of tyrosine hydroxylase (th) and dopamine transporter (dat) were detected by reverse transcriptase polymerase chain reaction and western blot analysis. |
2015-06-22 |
2023-08-13 |
Not clear |
| Bingjie Xie, Fankai Lin, Lei Peng, Kaleem Ullah, Hanyan Wu, Hong Qing, Yulin Den. Methylglyoxal increases dopamine level and leads to oxidative stress in SH-SY5Y cells. Acta biochimica et biophysica Sinica. vol 46. issue 11. 2015-06-22. PMID:25274329. |
the results showed that mgo induced an increase in th and dat expressions in sh-sy5y neuroblastoma cells, while the levels of dopamine, dopac, and endogenous neurotoxin salsolinol also increased. |
2015-06-22 |
2023-08-13 |
Not clear |
| Bingjie Xie, Fankai Lin, Lei Peng, Kaleem Ullah, Hanyan Wu, Hong Qing, Yulin Den. Methylglyoxal increases dopamine level and leads to oxidative stress in SH-SY5Y cells. Acta biochimica et biophysica Sinica. vol 46. issue 11. 2015-06-22. PMID:25274329. |
it was found that ag could decrease the reactive oxygen species (ros) level induced by mgo, but could not inhibit an increase of th, dat and dopamine. |
2015-06-22 |
2023-08-13 |
Not clear |
| Thomas Steinkellner, Liudmilla Mus, Birgit Eisenrauch, Andreea Constantinescu, Damiana Leo, Lisa Konrad, Mattias Rickhag, Gunnar Sørensen, Evgenia V Efimova, Eryan Kong, Matthäus Willeit, Tatyana D Sotnikova, Oliver Kudlacek, Ulrik Gether, Michael Freissmuth, Daniela D Pollak, Raul R Gainetdinov, Harald H Sitt. In vivo amphetamine action is contingent on αCaMKII. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 11. 2015-06-15. PMID:24871545. |
cocaine acts as a blocker at the transporters for dopamine (dat), serotonin (sert), and norepinephrine (net), but amphetamines are substrates that do not only block the uptake of monoamines but also induce substrate efflux by promoting reverse transport. |
2015-06-15 |
2023-08-13 |
mouse |
| Thomas Steinkellner, Liudmilla Mus, Birgit Eisenrauch, Andreea Constantinescu, Damiana Leo, Lisa Konrad, Mattias Rickhag, Gunnar Sørensen, Evgenia V Efimova, Eryan Kong, Matthäus Willeit, Tatyana D Sotnikova, Oliver Kudlacek, Ulrik Gether, Michael Freissmuth, Daniela D Pollak, Raul R Gainetdinov, Harald H Sitt. In vivo amphetamine action is contingent on αCaMKII. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 11. 2015-06-15. PMID:24871545. |
our findings demonstrate that amphetamine requires the presence of αcamkii to elicit a full-fledged effect on dat in vivo: αcamkii does not only support acute amphetamine-induced dopamine efflux but is also important in shaping the chronic response to amphetamine. |
2015-06-15 |
2023-08-13 |
mouse |
| Constantin Lapa, Timo S Spehl, Joachim Brumberg, Ioannis U Isaias, Susanne Schlögl, Michael Lassmann, Ken Herrmann, Philipp T Meye. Influence of CT-based attenuation correction on dopamine transporter SPECT with [(123)I]FP-CIT. American journal of nuclear medicine and molecular imaging. vol 5. issue 3. 2015-06-13. PMID:26069861. |
dopamine transporter (dat) imaging using single-photon emission computed tomography (spect) and (123)i-labelled radiopharmaceuticals like [(123)i]fp-cit is an established part in the diagnostic work-up of parkinsonism. |
2015-06-13 |
2023-08-13 |
Not clear |
| Juan Zhen, Tamara Antonio, Shu-Yuan Cheng, Solav Ali, Kymry T Jones, Maarten E A Reit. Dopamine transporter oligomerization: impact of combining protomers with differential cocaine analog binding affinities. Journal of neurochemistry. vol 133. issue 2. 2015-06-12. PMID:25580950. |
is each protomer an entirely separate unit that takes up dopamine and is inhibited by drugs known to block dat function? |
2015-06-12 |
2023-08-13 |
human |
| Juan Zhen, Tamara Antonio, Shu-Yuan Cheng, Solav Ali, Kymry T Jones, Maarten E A Reit. Dopamine transporter oligomerization: impact of combining protomers with differential cocaine analog binding affinities. Journal of neurochemistry. vol 133. issue 2. 2015-06-12. PMID:25580950. |
the dopamine transporter (dat) can exist as an oligomer but it is unknown whether the protomers function independently. |
2015-06-12 |
2023-08-13 |
human |
| Harald H Sitte, Gerhard J Schütz, Michael Freissmut. Cooperativity between individual transporter protomers: new data fuelling old complexes. Journal of neurochemistry. vol 133. issue 2. 2015-06-12. PMID:25772534. |
in a study by zhen and colleagues highlighted by this editorial in the current issue of journal of neurochemistry, the combination of mutant and wild-type dopamine transporter (dat) has been used to establish the cooperation between transporter protomers; the dat mutant version has an altered affinity for the radiolabelled inhibitor [³h]cft. |
2015-06-12 |
2023-08-13 |
Not clear |
| Lucia A Ruocco, Concetta Treno, Ugo A Gironi Carnevale, Claudio Arra, Gianpiero Boatto, Maria Nieddu, Cristina Pagano, Placido Illiano, Fabiana Barbato, Angela Tino, Ezio Carboni, Giovanni Laviola, Enza Lacivita, Marcello Leopoldo, Walter Adriani, Adolfo G Sadil. Prepuberal stimulation of 5-HT7-R by LP-211 in a rat model of hyper-activity and attention-deficit: permanent effects on attention, brain amino acids and synaptic markers in the fronto-striatal interface. PloS one. vol 9. issue 4. 2015-06-11. PMID:24709857. |
the quantity of l-glutamate (l-glu), l-aspartate (l-asp) and l-leucine (l-leu), dopamine transporter (dat), nmdar1 subunit and camkiiα, were assessed in prefrontal cortex (pfc), dorsal (ds) and ventral striatum (vs), for their role in synaptic transmission, neural plasticity and information processing. |
2015-06-11 |
2023-08-13 |
rat |
| Anderson Ravy Stolf, Claudia M Szobot, Ricardo Halpern, Gláucia C Akutagava-Martins, Diana Müller, Luciano S P Guimaraes, Felix H P Kessler, Flavio Pechansky, Tatiana Roma. Crack cocaine users show differences in genotype frequencies of the 3' UTR variable number of tandem repeats of the dopamine transporter gene (DAT1/SLC6A3). Neuropsychobiology. vol 70. issue 1. 2015-06-08. PMID:25247548. |
due to the mechanism of action of the dopamine transporter (dat) in drug addiction, the dat1 gene is a potential candidate for molecular studies. |
2015-06-08 |
2023-08-13 |
Not clear |
| Walter Koch, Marcus Unterrainer, Guoming Xiong, Peter Bartenstein, Markus Diemling, Andrea Varrone, John C Dickson, Livia Tossici-Bolt, Terez Sera, Susanne Asenbaum, Jan Booij, Ozlem L Kapucu, Andreas Kluge, Morten Ziebell, Jacques Darcourt, Flavio Nobili, Marco Pagani, Swen Hesse, Thierry Vander Borght, Koen Van Laere, Klaus Tatsch, Christian la Fougèr. Extrastriatal binding of [¹²³I]FP-CIT in the thalamus and pons: gender and age dependencies assessed in a European multicentre database of healthy controls. European journal of nuclear medicine and molecular imaging. vol 41. issue 10. 2015-06-05. PMID:24806112. |
apart from binding to the dopamine transporter (dat), [(123)i]fp-cit shows moderate affinity for the serotonin transporter (sert), allowing imaging of both monoamine transporters in a single imaging session in different brain areas. |
2015-06-05 |
2023-08-13 |
Not clear |
| Valtteri Kaasinen, Maija Kinos, Juho Joutsa, Marko Seppänen, Tommi Nopone. Differences in striatal dopamine transporter density between tremor dominant and non-tremor Parkinson's disease. European journal of nuclear medicine and molecular imaging. vol 41. issue 10. 2015-06-05. PMID:24867256. |
the present study investigated striatal dopamine transporter (dat) binding characteristics in a large sample of patients with and without tremor. |
2015-06-05 |
2023-08-13 |
Not clear |
| Krishnan Sriram, Amy M Jefferson, Gary X Lin, Aliakbar Afshari, Patti C Zeidler-Erdely, Terence G Meighan, Walter McKinney, Mark Jackson, Amy Cumpston, Jared L Cumpston, Howard D Leonard, David G Frazer, James M Antonin. Neurotoxicity following acute inhalation of aerosols generated during resistance spot weld-bonding of carbon steel. Inhalation toxicology. vol 26. issue 12. 2015-06-05. PMID:25265048. |
consistent with the decrease in th, lm also reduced the expression of dopamine transporter (slc6a3; dat), as well as, dopamine d2 receptor (drd2) in the olfactory bulb. |
2015-06-05 |
2023-08-13 |
rat |
| Vincent D Costa, Valery L Tran, Janita Turchi, Bruno B Averbec. Dopamine modulates novelty seeking behavior during decision making. Behavioral neuroscience. vol 128. issue 5. 2015-06-04. PMID:24911320. |
to test this hypothesis, we administered systemic injections of saline or gbr-12909, a selective dopamine transporter (dat) inhibitor, to monkeys and assessed their novelty seeking behavior during a probabilistic decision making task. |
2015-06-04 |
2023-08-13 |
monkey |
| Govindasamy Pushpavathi Selvakumar, Udaiyappan Janakiraman, Musthafa Mohamed Essa, Arokiasamy Justin Thenmozhi, Thamilarasan Manivasaga. Escin attenuates behavioral impairments, oxidative stress and inflammation in a chronic MPTP/probenecid mouse model of Parkinson's disease. Brain research. vol 1585. 2015-06-02. PMID:24657313. |
administration of mptp led to the depleted striatal dopamine content, impaired patterns of behavior, enhanced oxidative stress and diminished expression of tyrosine hydroxylase (th), dopamine transporter (dat) and vesicular monoamine transporter-2 (vmat-2). |
2015-06-02 |
2023-08-12 |
mouse |
| Mark A Rossi, Henry H Yi. Elevated dopamine alters consummatory pattern generation and increases behavioral variability during learning. Frontiers in integrative neuroscience. vol 9. 2015-06-01. PMID:26029064. |
increased dopamine in dat ko mice not only increased perseveration of bouts and individual lick duration, but also increased the behavioral variability in response to the extinction contingency and the rate of extinction. |
2015-06-01 |
2023-08-13 |
mouse |
| Foteini Delis, Christina Rombola, Robert Bellezza, Lauren Rosko, David K Grandy, Nora D Volkow, Panayotis K Thano. Regulation of ethanol intake under chronic mild stress: roles of dopamine receptors and transporters. Frontiers in behavioral neuroscience. vol 9. 2015-06-01. PMID:26029066. |
in order to identify neurochemical changes associated with the regulation of ethanol intake, we used in vitro receptor autoradiography to measure the levels and distribution of dopamine d1 and d2 receptors and dopamine transporters (dat). |
2015-06-01 |
2023-08-13 |
mouse |
| Tertia D Purves-Tyson, Samantha J Owens, Kay L Double, Reena Desai, David J Handelsman, Cynthia Shannon Weicker. Testosterone induces molecular changes in dopamine signaling pathway molecules in the adolescent male rat nigrostriatal pathway. PloS one. vol 9. issue 3. 2015-05-29. PMID:24618531. |
we hypothesized that molecular indices of dopamine neurotransmission [synthesis (tyrosine hydroxylase), breakdown (catechol-o-methyl transferase; monoamine oxygenase), transport [vesicular monoamine transporter (vmat), dopamine transporter (dat)] and receptors (drd1-d5)] would be changed by testosterone or its metabolites, dihydrotestosterone and 17β-estradiol, in the nigrostriatal pathway of adolescent male rats. |
2015-05-29 |
2023-08-12 |
rat |