| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Adriana Huertas, William D Wessinger, Yuri V Kucheryavykh, Priscila Sanabria, Misty J Eaton, Serguei N Skatchkov, Legier V Rojas, Gerónimo Maldonado-Martínez, Mikhail Y Inyushi. Quinine enhances the behavioral stimulant effect of cocaine in mice. Pharmacology, biochemistry, and behavior. vol 129. 2015-10-09. PMID:25482328. |
the na(+)-dependent dopamine transporter (dat) is primarily responsible for regulating free dopamine (da) concentrations in the brain by participating in the majority of da uptake; however, other da transporters may also participate, especially if cocaine or other drugs of abuse compromise dat. |
2015-10-09 |
2023-08-13 |
mouse |
| Brittany Butler, Shawn Goodwin, Kaustuv Saha, Jonas Becker, Danielle Sambo, Paran Davari, Habibeh Khoshboue. Dopamine Transporter Activity Is Modulated by α-synuclein. The Journal of biological chemistry. 2015-10-08. PMID:26048988. |
the duration and strength of the dopaminergic signal is regulated by the dopamine transporter (dat). |
2015-10-08 |
2023-08-13 |
Not clear |
| Santosh Dahal, Sai V P Chitti, Madhavan P N Nair, Shailendra K Saxen. Interactive effects of cocaine on HIV infection: implication in HIV-associated neurocognitive disorder and neuroAIDS. Frontiers in microbiology. vol 6. 2015-10-07. PMID:26441868. |
cocaine is a powerfully addictive central nervous system stimulating drug, which increases the level of neurotransmitter dopamine (da) in the brain, by blocking the dopamine transporters (dat) which is critical for da homeostasis and neurocognitive function. |
2015-10-07 |
2023-08-13 |
human |
| George Khelashvili, Harel Weinstei. Functional mechanisms of neurotransmitter transporters regulated by lipid-protein interactions of their terminal loops. Biochimica et biophysica acta. vol 1848. issue 9. 2015-09-30. PMID:25847498. |
recent experimental evidence implicates highly anionic phosphatidylinositol 4,5-biphosphate (pip(2)) lipids in such functions of the serotonin (sert) and dopamine (dat) transporters. |
2015-09-30 |
2023-08-13 |
Not clear |
| Stefanie H Grimm, Georg Höfner, Klaus T Wanne. Development and validation of an LC-ESI-MS/MS method for the triple reuptake inhibitor indatraline enabling its quantification in MS Binding Assays. Analytical and bioanalytical chemistry. vol 407. issue 2. 2015-09-28. PMID:25450050. |
we herein present the first lc-ms/ms quantification method for indatraline, a highly potent nonselective inhibitor of the three monoamine transporters (for dopamine, dat; norepinephrine, net; serotonin, sert), and its application to ms binding assays. |
2015-09-28 |
2023-08-13 |
Not clear |
| Shih-Hsien Lin, Kao Chin Chen, Sheng-Yu Lee, Nan Tsing Chiu, I Hui Lee, Po See Chen, Tzung Lieh Yeh, Ru-Band Lu, Chia-Chieh Chen, Mei-Hsiu Liao, Yen Kuang Yan. The association between heroin expenditure and dopamine transporter availability--a single-photon emission computed tomography study. Psychiatry research. vol 231. issue 3. 2015-09-28. PMID:25659472. |
the annual expenditure on heroin was assessed, and the availability of the dopamine transporter (dat) was assessed by single-photon emission computed tomography (spect) using [(99m)tc]trodat-1. |
2015-09-28 |
2023-08-13 |
Not clear |
| Jae Jung Lee, Jee Hyun Ham, Phil Hyu Lee, Young H Soh. Gender Differences in Age-Related Striatal Dopamine Depletion in Parkinson's Disease. Journal of movement disorders. vol 8. issue 3. 2015-09-28. PMID:26413240. |
in-vivo imaging studies demonstrated that women have greater striatal dopamine transporter (dat) activity than do men, both in the normal population and in pd patients. |
2015-09-28 |
2023-08-13 |
Not clear |
| Shaoang Tu, Jinlong Gao, Jia Liu, Jinming Zhang, Yiyun Huang, Shasha Xu, Mei Han, Jianhui Lian. Effects of Jitai tablet, a traditional Chinese medicine, on spontaneous withdrawal symptoms and modulation of dopaminergic functions in morphine-dependent rats. Phytotherapy research : PTR. vol 29. issue 5. 2015-09-25. PMID:25626992. |
our study has shown the following: (1) pre- and post-treatment with jtt were effective at alleviating the wet dog shakes and episodes of writhing; (2) pre-treatment with jtt inhibited the morphine-induced decreases in dopamine transporter (dat), dopamine d2 receptor (d2 r) and tyrosine hydroxylase (th) levels in the striatum (p < 0.01, compared with morphine group) and maintained them at normal levels; and (3) post-treatment with jtt restored the densities of dat, d2 r and th in the striatum to normal levels (p < 0.01, compared with morphine group). |
2015-09-25 |
2023-08-13 |
rat |
| Yasuko Kitagishi, Akari Minami, Atsuko Nakanishi, Yasunori Ogura, Satoru Matsud. Neuron membrane trafficking and protein kinases involved in autism and ADHD. International journal of molecular sciences. vol 16. issue 2. 2015-09-25. PMID:25647412. |
attention deficit hyperactivity disorder (adhd) is documented to dopaminergic insufficiencies, which is attributed to synaptic dysfunction of dopamine transporter (dat). |
2015-09-25 |
2023-08-13 |
Not clear |
| Minjung Seo, Minyoung Oh, Minjung Cho, Sun Ju Chung, Chong Sik Lee, Jae Seung Ki. The Effect of SSRIs on the Binding of (18)F-FP-CIT in Parkinson Patients: A Retrospective Case Control Study. Nuclear medicine and molecular imaging. vol 48. issue 4. 2015-09-23. PMID:26396633. |
(18)f-fp-cit [(18)f-fluorinated n-3-fluoropropyl-2-beta-carboxymethoxy-3-beta-(4-iodophenyl) nortropane] is useful for detecting striatal dopamine transporter (dat). |
2015-09-23 |
2023-08-13 |
Not clear |
| Sophie Sérrière, Aurélie Doméné, Johnny Vercouillie, Céline Mothes, Sylvie Bodard, Nuno Rodrigues, Denis Guilloteau, Sylvain Routier, Guylène Page, Sylvie Chalo. Assessment of the Protection of Dopaminergic Neurons by an α7 Nicotinic Receptor Agonist, PHA 543613 Using [(18)F]LBT-999 in a Parkinson's Disease Rat Model. Frontiers in medicine. vol 2. 2015-09-21. PMID:26389120. |
positron emission tomography (pet) imaging was performed at 7 days post-lesion using [(18)f]lbt-999 to quantify the striatal dopamine transporter (dat). |
2015-09-21 |
2023-08-13 |
rat |
| Gregory R Naumiec, Grace Lincourt, Jeremy P Clever, Michael A McGregor, Abraham Kovoor, Brenton DeBoe. Synthesis of a β-CCT-lanthanide conjugate for binding the dopamine transporter. Organic & biomolecular chemistry. vol 13. issue 9. 2015-09-18. PMID:25592739. |
the development of a β-cct-lanthanide conjugate that binds the dopamine transporter (dat) with high affinity (k(d) = 303 nm) is described. |
2015-09-18 |
2023-08-13 |
Not clear |
| Arkarup Banerjee, Fred Marbach, Francesca Anselmi, Matthew S Koh, Martin B Davis, Pedro Garcia da Silva, Kristen Delevich, Hassana K Oyibo, Priyanka Gupta, Bo Li, Dinu F Albean. An Interglomerular Circuit Gates Glomerular Output and Implements Gain Control in the Mouse Olfactory Bulb. Neuron. vol 87. issue 1. 2015-09-15. PMID:26139373. |
dopaminergic/gabaergic cells in the ob, which can be identified by their expression of the dopamine transporter (dat), provide the earliest opportunity for such crosstalk. |
2015-09-15 |
2023-08-13 |
mouse |
| F Trevizol, Kr Roversi, V T Dias, K Roversi, R C S Barcelos, F T Kuhn, C S Pase, R Golombieski, J C Veit, J Piccolo, D Pochmann, L O Porciúncula, T Emanuelli, J B T Rocha, M E Bürge. Cross-generational trans fat intake facilitates mania-like behavior: oxidative and molecular markers in brain cortex. Neuroscience. vol 286. 2015-09-14. PMID:25499313. |
in fact, the fo group showed minor amph-induced hyperactivity, decreased reactive species (rs) generation per se, causing no changes in protein carbonyl (pc) levels and dopamine transporter (dat). |
2015-09-14 |
2023-08-13 |
rat |
| Te-Chun Hsieh, Yu-Chin Wu, Shung-Shung Sun, Cheng-Nan Hsu, Chia-Hung Ka. Pituitary macroadenoma on 99mTc-TRODAT-1 brain SPECT. Clinical nuclear medicine. vol 39. issue 9. 2015-09-10. PMID:24445269. |
dopamine transporter (dat) radiopharmaceuticals are capable of binding to the dat with high selectivity, especially in the corpora striata, and have been widely used to evaluate parkinsonian disorder. |
2015-09-10 |
2023-08-12 |
Not clear |
| Erin S Calipari, Mark J Ferris, Cody A Siciliano, Sara R Jone. Differential influence of dopamine transport rate on the potencies of cocaine, amphetamine, and methylphenidate. ACS chemical neuroscience. vol 6. issue 1. 2015-09-10. PMID:25474655. |
dopamine transporter (dat) levels vary across brain regions and individuals, and are altered by drug history and disease states; however, the impact of altered dat expression on psychostimulant effects in brain has not been systematically explored. |
2015-09-10 |
2023-08-13 |
Not clear |
| Erin S Calipari, Mark J Ferris, Cody A Siciliano, Sara R Jone. Differential influence of dopamine transport rate on the potencies of cocaine, amphetamine, and methylphenidate. ACS chemical neuroscience. vol 6. issue 1. 2015-09-10. PMID:25474655. |
using fast scan cyclic voltammetry, we measured the effects of elevated dat levels on presynaptic dopamine parameters as well as the uptake inhibition potency of the blockers cocaine and methylphenidate (mph) and the releaser amphetamine (amph) in the nucleus accumbens core. |
2015-09-10 |
2023-08-13 |
Not clear |
| Yasemin Karabacak, Sunetra Sase, Yogesh D Aher, Ajinkya Sase, Sivaprakasam R Saroja, Ana Cicvaric, Harald Höger, Michael Berger, Vasiliy Bakulev, Harald H Sitte, Johann Leban, Francisco J Monje, Gert Lube. The effect of modafinil on the rat dopamine transporter and dopamine receptors D1-D3 paralleling cognitive enhancement in the radial arm maze. Frontiers in behavioral neuroscience. vol 9. 2015-09-08. PMID:26347626. |
modafinil was binding to the dat but insignificantly to sert or net and dopamine reuptake was blocked specifically (ic50 = 11.11 μm; sert 1547 μm; net 182 μm). |
2015-09-08 |
2023-08-13 |
rat |
| Ágnes Fehér, Anna Juhász, Magdolna Pákáski, János Kálmán, Zoltán Jank. Association between the 9 repeat allele of the dopamine transporter 40bp variable tandem repeat polymorphism and Alzheimer's disease. Psychiatry research. vol 220. issue 1-2. 2015-09-01. PMID:25130782. |
a case-control study was performed to investigate the association between the dopamine transporter (dat) gene (slc6a3) rs28363170 polymorphism and the risk for alzheimer's disease (ad). |
2015-09-01 |
2023-08-13 |
Not clear |
| Daniel Jenson, Kechun Yang, Alexandra Acevedo-Rodriguez, Amber Levine, John I Broussard, Jianrong Tang, John A Dan. Dopamine and norepinephrine receptors participate in methylphenidate enhancement of in vivo hippocampal synaptic plasticity. Neuropharmacology. vol 90. 2015-08-20. PMID:25445492. |
our hypothesis was that mph affects hippocampal synaptic plasticity underlying learning because mph boosts catecholamine signaling by blocking the dopamine and norepinephrine transporters (dat and net respectively). |
2015-08-20 |
2023-08-13 |
mouse |