| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thomas Steinkellner, Therese R Montgomery, Tina Hofmaier, Oliver Kudlacek, Jae-Won Yang, Mattias Rickhag, Gangsoo Jung, Gert Lubec, Ulrik Gether, Michael Freissmuth, Harald H Sitt. Amphetamine action at the cocaine- and antidepressant-sensitive serotonin transporter is modulated by αCaMKII. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 21. 2015-08-20. PMID:26019340. |
amphetamine-induced transport reversal at the closely related dopamine transporter (dat) has been shown previously to be contingent upon modulation by calmodulin kinase iiα (αcamkii). |
2015-08-20 |
2023-08-13 |
mouse |
| Yoshitoshi Shingai, Amane Tateno, Ryosuke Arakawa, Takeshi Sakayori, WooChan Kim, Hidenori Suzuki, Yoshiro Okub. Age-related decline in dopamine transporter in human brain using PET with a new radioligand [¹⁸F]FE-PE2I. Annals of nuclear medicine. vol 28. issue 3. 2015-08-19. PMID:24385293. |
dopamine transporter (dat) density is considered as a marker of pre-synaptic function. |
2015-08-19 |
2023-08-12 |
human |
| Suja Sadasivan, Joseph H Friedma. Experience with DaTscan at a tertiary referral center. Parkinsonism & related disorders. vol 21. issue 1. 2015-08-19. PMID:25465746. |
functional imaging of the dopamine transporter (dat) defines integrity of the striatal dopaminergic system and provides a marker for presynaptic neuronal degeneration. |
2015-08-19 |
2023-08-13 |
Not clear |
| Peter S Hasenhuetl, Klaus Schicker, Xaver Koenig, Yang Li, Subhodeep Sarker, Thomas Stockner, Sonja Sucic, Harald H Sitte, Michael Freissmuth, Walter Sandtne. Ligand Selectivity among the Dopamine and Serotonin Transporters Specified by the Forward Binding Reaction. Molecular pharmacology. vol 88. issue 1. 2015-08-11. PMID:25873594. |
the membrane transporters for the monoamines serotonin (sert) and dopamine (dat) are prominent targets of various psychoactive substances, including competitive inhibitors, such as tricyclic antidepressants, methylphenidate, and cocaine. |
2015-08-11 |
2023-08-13 |
Not clear |
| C Ortez, S T Duarte, A Ormazábal, M Serrano, A Pérez, R Pons, M Pineda, Z Yapici, E Fernández-Álvarez, R Domingo-Jiménez, P De Castro, R Artuch, A García-Cazorl. Cerebrospinal fluid synaptic proteins as useful biomarkers in tyrosine hydroxylase deficiency. Molecular genetics and metabolism. vol 114. issue 1. 2015-08-07. PMID:25468651. |
dopamine transporter (dat), d2-receptor and vesicular monoamine transporter (vmat2) were measured in the csf of 10 subjects with th deficiency by western blot analysis. |
2015-08-07 |
2023-08-13 |
human |
| David J Heal, Jane Gosden, Sharon L Smit. Dopamine reuptake transporter (DAT) "inverse agonism"--a novel hypothesis to explain the enigmatic pharmacology of cocaine. Neuropharmacology. vol 87. 2015-08-04. PMID:24953830. |
dopamine reuptake transporter (dat) "inverse agonism"--a novel hypothesis to explain the enigmatic pharmacology of cocaine. |
2015-08-04 |
2023-08-13 |
human |
| David J Heal, Jane Gosden, Sharon L Smit. Dopamine reuptake transporter (DAT) "inverse agonism"--a novel hypothesis to explain the enigmatic pharmacology of cocaine. Neuropharmacology. vol 87. 2015-08-04. PMID:24953830. |
we describe the experimental findings which suggest cocaine serves as a negative allosteric modulator to alter the function of the dopamine reuptake transporter (dat) and reverse its direction of transport. |
2015-08-04 |
2023-08-13 |
human |
| David J Heal, Jane Gosden, Sharon L Smit. Dopamine reuptake transporter (DAT) "inverse agonism"--a novel hypothesis to explain the enigmatic pharmacology of cocaine. Neuropharmacology. vol 87. 2015-08-04. PMID:24953830. |
because the physiological role of dat is to remove dopamine from the synapse and the action of cocaine is the opposite of this, we have postulated that cocaine's effect is analogous to an inverse agonist. |
2015-08-04 |
2023-08-13 |
human |
| Julien Vezoli, Kwamivi Dzahini, Nicolas Costes, Charles R E Wilson, Karim Fifel, Howard M Cooper, Henry Kennedy, Emmanuel Procy. Increased DAT binding in the early stage of the dopaminergic lesion: a longitudinal [11C]PE2I binding study in the MPTP-monkey. NeuroImage. vol 102 Pt 2. 2015-08-03. PMID:25108180. |
we measured the binding potential of the selective dopamine active transporter (dat) radiotracer [(11)c]pe2i in mptp-treated macaque monkeys, thus establishing a detailed profile of the nigrostriatal da status following mptp intoxication and its relation to induced motor and non-motor symptoms. |
2015-08-03 |
2023-08-13 |
monkey |
| Zongchang Li, Ying He, Jinsong Tang, Xiaofen Zong, Maolin Hu, Xiaogang Che. Molecular imaging of striatal dopamine transporters in major depression--a meta-analysis. Journal of affective disorders. vol 174. 2015-08-03. PMID:25497470. |
increasing studies have revealed the dopamine transporter (dat) availability altered in striatum associated with major depression. |
2015-08-03 |
2023-08-13 |
Not clear |
| Manuela C Matesan, Donna J Cross, David H Lewis, Satoshi Minoshim. Differential alterations of dopamine transporter in the striatum and midbrain in patients with parkinsonian syndrome. Clinical nuclear medicine. vol 40. issue 3. 2015-07-30. PMID:25546191. |
in this study, we examined dopamine transporter (dat) density in the striatum versus midbrain (mb) in patients with nigrostriatal denervation. |
2015-07-30 |
2023-08-13 |
Not clear |
| Jason R Richardson, Michele M Taylor, Stuart L Shalat, Thomas S Guillot, W Michael Caudle, Muhammad M Hossain, Tiffany A Mathews, Sara R Jones, Deborah A Cory-Slechta, Gary W Mille. Developmental pesticide exposure reproduces features of attention deficit hyperactivity disorder. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 29. issue 5. 2015-07-30. PMID:25630971. |
mice exposed to the pyrethroid pesticide deltamethrin during development exhibit several features reminiscent of adhd, including elevated dopamine transporter (dat) levels, hyperactivity, working memory and attention deficits, and impulsive-like behavior. |
2015-07-30 |
2023-08-13 |
mouse |
| Kai-Chun Yang, Shyh-Jen Wang, Wen-Chi Hsieh, Jiing-Feng Lirng, Chen-Chang Yang, Jou-Fang Deng, Chun-Lung Lin, Yuan-Hwa Cho. Longitudinal changes in the dopamine transporter and cognition in suicide attempters with charcoal burning. Psychiatry research. vol 231. issue 2. 2015-07-29. PMID:25572798. |
this study was designed to elucidate associations between changes in the dopamine transporter (dat) and cognitive function in patients following co poisoning during a follow-up period of 6 months. |
2015-07-29 |
2023-08-13 |
human |
| Stephen J Kohut, Takato Hiranita, Soo-Kyung Hong, Aaron L Ebbs, Valeria Tronci, Jennifer Green, Linda Garcés-Ramírez, Lauren E Chun, Maddalena Mereu, Amy H Newman, Jonathan L Katz, Gianluigi Tand. Preference for distinct functional conformations of the dopamine transporter alters the relationship between subjective effects of cocaine and stimulation of mesolimbic dopamine. Biological psychiatry. vol 76. issue 10. 2015-07-27. PMID:24853388. |
subjective effects of cocaine are mediated primarily by dopamine (da) transporter (dat) blockade. |
2015-07-27 |
2023-08-13 |
Not clear |
| Mariana Raineri, Betina González, Celeste Rivero-Echeto, Javier A Muñiz, María Laura Gutiérrez, Carolina I Ghanem, Jean Lud Cadet, Edgar García-Rill, Francisco J Urbano, Veronica Bisagn. Differential effects of environment-induced changes in body temperature on modafinil's actions against methamphetamine-induced striatal toxicity in mice. Neurotoxicity research. vol 27. issue 1. 2015-07-27. PMID:25261212. |
brains were dissected out 6 days after treatments and processed for tyrosine hydroxylase (th), dopamine transporter (dat), gfap and c-fos immunohistochemistry. |
2015-07-27 |
2023-08-13 |
mouse |
| Marcello Moccia, Sabina Pappatà, Marina Picillo, Roberto Erro, Anna Rita Daniela Coda, Katia Longo, Carmine Vitale, Marianna Amboni, Arturo Brunetti, Giuseppe Capo, Marco Salvatore, Paolo Barone, Maria Teresa Pellecchi. Dopamine transporter availability in motor subtypes of de novo drug-naïve Parkinson's disease. Journal of neurology. vol 261. issue 11. 2015-07-24. PMID:25119838. |
in this study, we investigated with fp-cit spect the striatal dopamine transporter (dat) availability in drug-naïve pd patients with art and td phenotypes. |
2015-07-24 |
2023-08-13 |
Not clear |
| Lucy G Chastain, Hongyan Qu, Chase H Bourke, P Michael Iuvone, Paul R Dobner, Charles B Nemeroff, Becky Kinkea. Striatal dopamine receptor plasticity in neurotensin deficient mice. Behavioural brain research. vol 280. 2015-07-24. PMID:25449842. |
however, nt(-/-) mice showed significantly increased d1 receptor, d2 receptor, and dopamine transporter (dat) mrna in the caudate putamen compared to nt(+/+) controls. |
2015-07-24 |
2023-08-13 |
mouse |
| Patrik Fazio, Per Svenningsson, Anton Forsberg, Erik G Jönsson, Nahid Amini, Ryuji Nakao, Sangram Nag, Christer Halldin, Lars Farde, Andrea Varron. Quantitative Analysis of ¹⁸F-(E)-N-(3-Iodoprop-2-Enyl)-2β-Carbofluoroethoxy-3β-(4'-Methyl-Phenyl) Nortropane Binding to the Dopamine Transporter in Parkinson Disease. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 56. issue 5. 2015-07-24. PMID:25791993. |
(18)f-(e)-n-(3-iodoprop-2-enyl)-2β-carbofluoroethoxy-3β-(4'-methyl-phenyl) nortropane ((18)f-fe-pe2i) is a recently developed radioligand for the in vivo quantification of the dopamine transporter (dat) in the striatum and substantia nigra (sn). |
2015-07-24 |
2023-08-13 |
Not clear |
| Chong S Lee, Su-Jeong Kim, Seung Jun Oh, Hye Ok Kim, Sung-Cheol Yun, Doris Doudet, Jae Seung Ki. Uneven age effects of [(18)F]FP-CIT binding in the striatum of Parkinson's disease. Annals of nuclear medicine. vol 28. issue 9. 2015-07-23. PMID:25008292. |
dopamine transporter (dat) imaging shows age-related decline of ligand binding in the normal striatum, a decline attributed to regulatory changes. |
2015-07-23 |
2023-08-13 |
Not clear |
| S Sommer, W Danysz, H Russ, B Valastro, G Flik, W Haube. The dopamine reuptake inhibitor MRZ-9547 increases progressive ratio responding in rats. The international journal of neuropsychopharmacology. vol 17. issue 12. 2015-07-21. PMID:24964269. |
results reveal that mrz-9547 is a selective dopamine transporter (dat) inhibitor that moderately stimulated striatal dopamine release. |
2015-07-21 |
2023-08-13 |
rat |