| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Laura E O'Dell, Luis A Natividad, Joseph A Pipkin, Francisco Roman, Ivan Torres, Jesus Jurado, Oscar V Torres, Theodore C Friedman, John M Tenayuca, Arbi Nazaria. Enhanced nicotine self-administration and suppressed dopaminergic systems in a rat model of diabetes. Addiction biology. vol 19. issue 6. 2015-07-20. PMID:23834715. |
in order to examine the contribution of dopamine to our behavioral effects, dopamine transporter (dat), d1 and d2 receptor levels were compared in the nucleus accumbens (nac) following 10 days of nicotine or saline ivsa. |
2015-07-20 |
2023-08-12 |
rat |
| Xiaoqi Pan, Xiongxiong Guo, Fei Xiong, Guihong Cheng, Qing Lu, Hong Ya. Acrylamide increases dopamine levels by affecting dopamine transport and metabolism related genes in the striatal dopaminergic system. Toxicology letters. vol 236. issue 1. 2015-07-20. PMID:25943760. |
in addition, dopamine transporter (dat) and vesicular monoamine transporter 2 (vmat2) expression levels were both down-regulated in the striatum. |
2015-07-20 |
2023-08-13 |
rat |
| Tzu-Cheng Lee, Justin R Ellin, Qiu Huang, Uttam Shrestha, Grant T Gullberg, Youngho Se. Multipinhole collimator with 20 apertures for a brain SPECT application. Medical physics. vol 41. issue 11. 2015-07-16. PMID:25370660. |
in this paper, the authors show a possibility of over an order of magnitude enhancement in photon detection efficiency (from 7.6 × 10(-5) to 1.6 × 10(-3)) for dopamine transporter (dat) imaging of the striatum over the conventional spect parallel-hole collimators by use of custom-designed 20 multipinhole (20-mph) collimators with apertures of 0.75 cm diameter. |
2015-07-16 |
2023-08-13 |
Not clear |
| Haiyin Wu, Brian O'Neill, Dawn D Han, Keerthi Thirtamara-Rajamani, Yanlin Wang, Howard H G. Restoration of cocaine stimulation and reward by reintroducing wild type dopamine transporter in adult knock-in mice with a cocaine-insensitive dopamine transporter. Neuropharmacology. vol 86. 2015-07-14. PMID:24835281. |
in previous studies, we generated knock-in mice with a cocaine-insensitive dopamine transporter (dat-ci mice) and found cocaine does not stimulate locomotion or produce reward in these mice, indicating dat inhibition is necessary for cocaine stimulation and reward. |
2015-07-14 |
2023-08-13 |
mouse |
| Bronwyn Kivell, Zeljko Uzelac, Santhanalakshmi Sundaramurthy, Jeyaganesh Rajamanickam, Amy Ewald, Vladimir Chefer, Vanaja Jaligam, Elizabeth Bolan, Bridget Simonson, Balasubramaniam Annamalai, Padmanabhan Mannangatti, Thomas E Prisinzano, Ivone Gomes, Lakshmi A Devi, Lankupalle D Jayanthi, Harald H Sitte, Sammanda Ramamoorthy, Toni S Shippenber. Salvinorin A regulates dopamine transporter function via a kappa opioid receptor and ERK1/2-dependent mechanism. Neuropharmacology. vol 86. 2015-07-14. PMID:25107591. |
the dopamine transporter (dat) regulates dopamine transmission via uptake of released neurotransmitter. |
2015-07-14 |
2023-08-13 |
Not clear |
| Bronwyn Kivell, Zeljko Uzelac, Santhanalakshmi Sundaramurthy, Jeyaganesh Rajamanickam, Amy Ewald, Vladimir Chefer, Vanaja Jaligam, Elizabeth Bolan, Bridget Simonson, Balasubramaniam Annamalai, Padmanabhan Mannangatti, Thomas E Prisinzano, Ivone Gomes, Lakshmi A Devi, Lankupalle D Jayanthi, Harald H Sitte, Sammanda Ramamoorthy, Toni S Shippenber. Salvinorin A regulates dopamine transporter function via a kappa opioid receptor and ERK1/2-dependent mechanism. Neuropharmacology. vol 86. 2015-07-14. PMID:25107591. |
kors are apposed to dat in dopamine nerve terminals suggesting an additional target by which sala modulates dopamine transmission. |
2015-07-14 |
2023-08-13 |
Not clear |
| Mariane Cristovão Bagatin, Camila Santos Suniga Tozatti, Layara Akemi Abiko, Diego Alberto dos Santos Yamazaki, Priscila Rebeca Alves Silva, Leonardo Martins Perego, Elisabeth Aparecida Audi, Flavio Augusto Vicente Seixas, Ernani Abicht Basso, Gisele de Freitas Gauz. Molecular docking and panicolytic effect of 8-prenylnaringenin in the elevated T-maze. Chemical & pharmaceutical bulletin. vol 62. issue 12. 2015-07-14. PMID:25450631. |
to evaluate the interactions of 8-pn with monoamine transporters, a docking study was performed for both the r and s configurations of 8-pn towards sert, norepinephrine (net) and dopamine transporters (dat). |
2015-07-14 |
2023-08-13 |
rat |
| Yao Lu, Nicolette Driscoll, Ilker Ozden, Zeyang Yu, Arto V Nurmikk. Modulating dopamine release by optogenetics in transgenic mice reveals terminal dopaminergic dynamics. Neurophotonics. vol 2. issue 3. 2015-07-14. PMID:26171413. |
we demonstrate here the use of cell-type-specific optogenetic targeting in conjunction with fast-scan cyclic voltammetry applied to brain slices prepared from specifically tailored transgenic mice, which conditionally express channelrhodopsin-2 (chr2) through dopamine transporter (dat)-cre. |
2015-07-14 |
2023-08-13 |
mouse |
| Donald G Grosset, Klaus Tatsch, Wolfgang H Oertel, Eduardo Tolosa, Nin Bajaj, Andreas Kupsch, John T O'Brien, John Seibyl, Zuzana Walker, Paul Sherwin, Chris Chen, Igor D Grache. Safety analysis of 10 clinical trials and for 13 years after first approval of ioflupane 123I injection (DaTscan). Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 55. issue 8. 2015-07-13. PMID:24947061. |
ioflupane is an analog of cocaine that binds reversibly with high affinity to the dopamine transporter (dat) protein, a marker for presynaptic terminals in dopaminergic nigrostriatal neurons. |
2015-07-13 |
2023-08-13 |
human |
| Alanna C Easton, Andrea Rotter, Anbarasu Lourdusamy, Sylvane Desrivières, Alberto Fernández-Medarde, Teresa Biermann, Cathy Fernandes, Eugenio Santos, Johannes Kornhuber, Gunter Schumann, Christian P Mülle. Rasgrf2 controls dopaminergic adaptations to alcohol in mice. Brain research bulletin. vol 109. 2015-07-10. PMID:25454123. |
there was no difference in the expression of dopamine transporter (dat), dopamine receptor regulating factor (drrf), or dopamine d2 receptor (drd2) mrna in the brain between rasgrf2 ko and wt mice. |
2015-07-10 |
2023-08-13 |
mouse |
| Abigail Z Rajala, Ismail Zaitoun, Jeffrey B Henriques, Alexander K Converse, Dhanabalan Murali, Miles L Epstein, Luis C Populi. Dopamine transporter gene susceptibility to methylation is associated with impulsivity in nonhuman primates. Journal of neurophysiology. vol 112. issue 9. 2015-07-08. PMID:25122707. |
impulsivity, the predisposition to act without regard for negative consequences, is a characteristic of several psychiatric disorders and is thought to result in part from genetic variation in the untranslated region of the dopamine transporter (dat) gene. |
2015-07-08 |
2023-08-13 |
human |
| Abigail Z Rajala, Ismail Zaitoun, Jeffrey B Henriques, Alexander K Converse, Dhanabalan Murali, Miles L Epstein, Luis C Populi. Dopamine transporter gene susceptibility to methylation is associated with impulsivity in nonhuman primates. Journal of neurophysiology. vol 112. issue 9. 2015-07-08. PMID:25122707. |
higher dat availability lowers dopamine levels, potentially altering neuronal circuits involved in the initiation of action, thus contributing to the impulsive phenotype. |
2015-07-08 |
2023-08-13 |
human |
| Javier A Urra, Franz Villaroel-Espíndola, Alejandra A Covarrubias, Joan Enric Rodríguez-Gil, Alfredo Ramírez-Reveco, Ilona I Conch. Presence and function of dopamine transporter (DAT) in stallion sperm: dopamine modulates sperm motility and acrosomal integrity. PloS one. vol 9. issue 11. 2015-07-08. PMID:25402186. |
presence and function of dopamine transporter (dat) in stallion sperm: dopamine modulates sperm motility and acrosomal integrity. |
2015-07-08 |
2023-08-13 |
Not clear |
| Javier A Urra, Franz Villaroel-Espíndola, Alejandra A Covarrubias, Joan Enric Rodríguez-Gil, Alfredo Ramírez-Reveco, Ilona I Conch. Presence and function of dopamine transporter (DAT) in stallion sperm: dopamine modulates sperm motility and acrosomal integrity. PloS one. vol 9. issue 11. 2015-07-08. PMID:25402186. |
in the present study, using immunodetection methods, we revealed the presence of several proteins important for the dopamine uptake and signalling in mammalian sperm, specifically monoamine transporters as dopamine (dat), serotonin (sert) and norepinephrine (net) transporters in equine sperm. |
2015-07-08 |
2023-08-13 |
Not clear |
| Javier A Urra, Franz Villaroel-Espíndola, Alejandra A Covarrubias, Joan Enric Rodríguez-Gil, Alfredo Ramírez-Reveco, Ilona I Conch. Presence and function of dopamine transporter (DAT) in stallion sperm: dopamine modulates sperm motility and acrosomal integrity. PloS one. vol 9. issue 11. 2015-07-08. PMID:25402186. |
in summary, our results revealed the presence of monoamine transporter dat, net and sert in equine sperm, and that the dopamine uptake by dat can regulate sperm function, specifically acrosomal integrity and sperm motility. |
2015-07-08 |
2023-08-13 |
Not clear |
| Richard B Rothman, Subramaniam Ananthan, John S Partilla, Surendra K Saini, Omar Moukha-Chafiq, Vibha Pathak, Michael H Bauman. Studies of the biogenic amine transporters 15. Identification of novel allosteric dopamine transporter ligands with nanomolar potency. The Journal of pharmacology and experimental therapeutics. vol 353. issue 3. 2015-07-08. PMID:25788711. |
novel allosteric modulators of the dopamine transporter (dat) have been identified. |
2015-07-08 |
2023-08-13 |
rat |
| Richard B Rothman, Subramaniam Ananthan, John S Partilla, Surendra K Saini, Omar Moukha-Chafiq, Vibha Pathak, Michael H Bauman. Studies of the biogenic amine transporters 15. Identification of novel allosteric dopamine transporter ligands with nanomolar potency. The Journal of pharmacology and experimental therapeutics. vol 353. issue 3. 2015-07-08. PMID:25788711. |
we have shown previously that sri-9804 [n-(diphenylmethyl)-2-phenyl-4-quinazolinamine], sri-20040 [n-(2,2-diphenylethyl)-2-phenyl-4-quinazolinamine], and sri-20041 [n-(3,3-diphenylpropyl)-2-phenyl-4-quinazolinamine] partially inhibit [(125)i]rti-55 ([(125)i]3β-(4'-iodophenyl)tropan-2β-carboxylic acid methyl ester) binding and [(3)h]dopamine ([(3)h]da) uptake, slow the dissociation rate of [(125)i]rti-55 from the dat, and allosterically modulate d-amphetamine-induced, dat-mediated da release. |
2015-07-08 |
2023-08-13 |
rat |
| Jordy van Enkhuizen, Brook L Henry, Arpi Minassian, William Perry, Morgane Milienne-Petiot, Kerin K Higa, Mark A Geyer, Jared W Youn. Reduced dopamine transporter functioning induces high-reward risk-preference consistent with bipolar disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 13. 2015-07-07. PMID:25005251. |
the mechanisms underlying this behavioral deficit are unknown, but may include the reduced dopamine transporter (dat) functioning reported in bd patients. |
2015-07-07 |
2023-08-13 |
mouse |
| Chien-Chin Hsu, Yen-Hsiang Chang, Wei-Che Lin, Shu-Wen Tang, Pei-Wen Wang, Yung-Cheng Huang, Nan-Tsing Chi. The feasibility of using CT-guided ROI for semiquantifying striatal dopamine transporter availability in a hybrid SPECT/CT system. TheScientificWorldJournal. vol 2014. 2015-07-02. PMID:25531005. |
ct-guided region of interest (roi) for semiquantifying striatal dopamine transporter (dat) availability may be a feasible method. |
2015-07-02 |
2023-08-13 |
Not clear |
| Kathrin Koblinger, Tamás Füzesi, Jillian Ejdrygiewicz, Aleksandra Krajacic, Jaideep S Bains, Patrick J Whela. Characterization of A11 neurons projecting to the spinal cord of mice. PloS one. vol 9. issue 10. 2015-06-29. PMID:25343491. |
on the contrary, a11 neurons in the mouse lack the dopamine transporter (dat). |
2015-06-29 |
2023-08-13 |
mouse |