| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marco Niello, Daniela Cintulová, Philip Raithmayr, Marion Holy, Kathrin Jäntsch, Claire Colas, Gerhard F Ecker, Harald H Sitte, Marko D Mihovilovi. Effects of Hydroxylated Mephedrone Metabolites on Monoamine Transporter Activity Frontiers in pharmacology. vol 12. 2021-04-28. PMID:33897439. |
it elicits the release of monoamines via the high affinity transporters for dopamine (dat), norepinephrine (net) and serotonin (sert). |
2021-04-28 |
2023-08-13 |
Not clear |
| Tanya Simuni, Michael C Brumm, Liz Uribe, Chelsea Caspell-Garcia, Christopher S Coffey, Andrew Siderowf, Roy N Alcalay, John Q Trojanowski, Leslie M Shaw, John Seibyl, Andrew Singleton, Arthur W Toga, Doug Galasko, Tatiana Foroud, Kelly Nudelman, Duygu Tosun-Turgut, Kathleen Poston, Daniel Weintraub, Brit Mollenhauer, Caroline M Tanner, Karl Kieburtz, Lana M Chahine, Alyssa Reimer, Samantha Hutten, Susan Bressman, Kenneth Mare. Clinical and Dopamine Transporter Imaging Characteristics of Leucine Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson's Disease Participants in the Parkinson's Progression Markers Initiative: A Cross-Sectional Study. Movement disorders : official journal of the Movement Disorder Society. vol 35. issue 5. 2021-04-27. PMID:32073681. |
there are limited data on the phenotypic and dopamine transporter (dat) imaging characterization of the parkinson's disease (pd) patients with leucine rich kinase 2 (lrrk2) and glucosylceramidase beta (gba) mutations. |
2021-04-27 |
2023-08-13 |
human |
| Alicia Garrido, Alex Iranzo, Ambra Stefani, Mònica Serradell, Amaia Muñoz-Lopetegi, Paula Marrero, Birgit Högl, Carles Gaig, Joan Santamaria, Eduard Tolosa, Werner Poew. Lack of Asymmetry of Nigrostriatal Dopaminergic Function in Healthy Subjects. Movement disorders : official journal of the Movement Disorder Society. vol 35. issue 6. 2021-04-27. PMID:32141653. |
in right-handed patients with parkinson's disease (pd) or isolated rapid eye movement sleep behavior disorder, dopamine transporter (dat) [(123)i]β-carboxymethyoxy-3-β-(4-iodophenyl) tropane single photon emission computed tomography (spect) shows predominant nigrostriatal deficit in the left striatum. |
2021-04-27 |
2023-08-13 |
human |
| Reeree Lee, Jung Hwan Shin, Hongyoon Choi, Han-Joon Kim, Gi Jeong Cheon, Beomseok Jeo. Variability of FP-CIT PET Patterns Associated With Clinical Features of Multiple System Atrophy. Neurology. vol 96. issue 12. 2021-04-22. PMID:33536274. |
to validate the role of the dopamine transporter (dat) imaging as a biomarker in multiple system atrophy (msa), we analyzed the association between spatial patterns of [ |
2021-04-22 |
2023-08-13 |
Not clear |
| Rocío Guerrero-Bautista, Aurelio Franco-García, Juana M Hidalgo, Francisco José Fernández-Gómez, Bruno Ribeiro Do Couto, M Victoria Milanés, Cristina Núñe. Distinct Regulation of Dopamine D3 Receptor in the Basolateral Amygdala and Dentate Gyrus during the Reinstatement of Cocaine CPP Induced by Drug Priming and Social Stress. International journal of molecular sciences. vol 22. issue 6. 2021-04-21. PMID:33803578. |
reinstatement of cocaine cpp paralleled an increasing trend in d3r and dopamine transporter (dat) levels in the bla. |
2021-04-21 |
2023-08-13 |
Not clear |
| Takao Setsu, Yusuke Hamada, Daisuke Oikawa, Tomohisa Mori, Yozo Ishiuji, Daisuke Sato, Michiko Narita, Shogo Miyazaki, Eri Furuta, Yukari Suda, Hiroyasu Sakai, Takahiro Ochiya, Hiroyuki Tezuka, Masako Iseki, Eiichi Inada, Akihiro Yamanaka, Naoko Kuzumaki, Minoru Narit. Direct evidence that the brain reward system is involved in the control of scratching behaviors induced by acute and chronic itch. Biochemical and biophysical research communications. vol 534. 2021-04-19. PMID:33220930. |
the induction of Δfosb, a member of the fos family of transcription factors, was observed in dopamine transporter (dat)-positive dopamine neurons in the ventral tegmental area (vta) of mice suffering from a chronic itch sensation. |
2021-04-19 |
2023-08-13 |
mouse |
| Ulrika H Julku, Maria Jäntti, Reinis Svarcbahs, Timo T Myöhäne. Prolyl Oligopeptidase Regulates Dopamine Transporter Oligomerization and Phosphorylation in a PKC- and ERK-Independent Manner. International journal of molecular sciences. vol 22. issue 4. 2021-04-19. PMID:33579026. |
additionally, we have shown that prep regulates phosphorylation and internalization of dopamine transporter (dat) in mice. |
2021-04-19 |
2023-08-13 |
mouse |
| Ulrika H Julku, Maria Jäntti, Reinis Svarcbahs, Timo T Myöhäne. Prolyl Oligopeptidase Regulates Dopamine Transporter Oligomerization and Phosphorylation in a PKC- and ERK-Independent Manner. International journal of molecular sciences. vol 22. issue 4. 2021-04-19. PMID:33579026. |
we tested the effects of prep, prep inhibition, and alpha-synuclein on prep-related dat regulation by using western blot analysis and a dopamine uptake assay, and characterized the impact of prep on protein kinase c (pkc) and extracellular signal-regulated kinase (erk) by using pkc assay and western blot, respectively, as these kinases regulate dat phosphorylation. |
2021-04-19 |
2023-08-13 |
mouse |
| Ulrika H Julku, Maria Jäntti, Reinis Svarcbahs, Timo T Myöhäne. Prolyl Oligopeptidase Regulates Dopamine Transporter Oligomerization and Phosphorylation in a PKC- and ERK-Independent Manner. International journal of molecular sciences. vol 22. issue 4. 2021-04-19. PMID:33579026. |
our results confirmed our previous findings that a lack of prep can increase phosphorylation and internalization of dat and decrease uptake of dopamine. |
2021-04-19 |
2023-08-13 |
mouse |
| José A Pino, Gabriel Nuñez-Vivanco, Gabriela Hidalgo, Miguel Reyes Parada, Habibeh Khoshbouei, Gonzalo E Torre. Identification of Critical Residues in the Carboxy Terminus of the Dopamine Transporter Involved in the G Protein βγ-Induced Dopamine Efflux. Frontiers in pharmacology. vol 12. 2021-04-14. PMID:33841159. |
the dopamine transporter (dat) plays a crucial role in the regulation of brain dopamine (da) homeostasis through the re-uptake of da back into the presynaptic terminal. |
2021-04-14 |
2023-08-13 |
Not clear |
| Placido Illiano, Gregory E Bigford, Raul R Gainetdinov, Marta Pard. Rats Lacking Dopamine Transporter Display Increased Vulnerability and Aberrant Autonomic Response to Acute Stress. Biomolecules. vol 10. issue 6. 2021-04-08. PMID:32486390. |
dopamine transporter (dat) plays a key role in the regulation of the hpa axis. |
2021-04-08 |
2023-08-13 |
rat |
| Md Ashequr Rahman, Richard Laforest, Abhinav K Jh. A LIST-MODE OSEM-BASED ATTENUATION AND SCATTER COMPENSATION METHOD FOR SPECT. Proceedings. IEEE International Symposium on Biomedical Imaging. vol 2020. 2021-04-02. PMID:33072242. |
the method was objectively evaluated using realistic simulation studies on the task of estimating uptake in the striatal regions of the brain in a 2-d dopamine transporter (dat)-scan spect study. |
2021-04-02 |
2023-08-13 |
Not clear |
| Tarique R Bagalkot, Ethan R Block, Kristen Bucchin, Judith Joyce Balcita-Pedicino, Michael Calderon, Susan R Sesack, Alexander Sorki. Dopamine Transporter Localization in Medial Forebrain Bundle Axons Indicates Its Long-Range Transport Primarily by Membrane Diffusion with a Limited Contribution of Vesicular Traffic on Retromer-Positive Compartments. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 2. 2021-03-25. PMID:33234607. |
dopamine transporter (dat) controls dopamine neurotransmission by clearing synaptically released dopamine. |
2021-03-25 |
2023-08-13 |
mouse |
| Suzanne M Underhill, Mark S Colt, Susan G Amar. Amphetamine Stimulates Endocytosis of the Norepinephrine and Neuronal Glutamate Transporters in Cultured Locus Coeruleus Neurons. Neurochemical research. vol 45. issue 6. 2021-03-22. PMID:31912366. |
in addition, amphs have been shown to activate endocytosis of the dopamine transporter (dat) which further elevates extracellular dopamine (da). |
2021-03-22 |
2023-08-13 |
Not clear |
| Erfan Heidari, Ehsan Razmara, Sareh Hosseinpour, Ali Reza Tavasoli, Masoud Garshasb. Homozygous in-frame variant of SCL6A3 causes dopamine transporter deficiency syndrome in a consanguineous family. Annals of human genetics. vol 84. issue 4. 2021-03-22. PMID:32077500. |
the extracellular loops are crucial for dat activity and defects in these regions disturb dopamine transport. |
2021-03-22 |
2023-08-13 |
human |
| Mengfei Bu, Matthew J Farrer, Habibeh Khoshboue. Dynamic control of the dopamine transporter in neurotransmission and homeostasis. NPJ Parkinson's disease. vol 7. issue 1. 2021-03-20. PMID:33674612. |
the dopamine transporter (dat) transports extracellular dopamine into the intracellular space contributing to the regulation of dopamine neurotransmission. |
2021-03-20 |
2023-08-13 |
Not clear |
| Mengfei Bu, Matthew J Farrer, Habibeh Khoshboue. Dynamic control of the dopamine transporter in neurotransmission and homeostasis. NPJ Parkinson's disease. vol 7. issue 1. 2021-03-20. PMID:33674612. |
a reduction of dat density is implicated in parkinson's disease (pd) by neuroimaging; dopamine turnover is dopamine turnover is elevated in early symptomatic pd and in presymptomatic individuals with monogenic mutations causal for parkinsonism. |
2021-03-20 |
2023-08-13 |
Not clear |
| Mengfei Bu, Matthew J Farrer, Habibeh Khoshboue. Dynamic control of the dopamine transporter in neurotransmission and homeostasis. NPJ Parkinson's disease. vol 7. issue 1. 2021-03-20. PMID:33674612. |
as an integral plasma membrane protein, dat surface expression is dynamically regulated through endocytic trafficking, enabling flexible control of dopamine signaling in time and space, which in turn critically modulates movement, motivation and learning behavior. |
2021-03-20 |
2023-08-13 |
Not clear |
| Placido Illiano, Damiana Leo, Raul R Gainetdinov, Marta Pard. Early Adolescence Prefrontal Cortex Alterations in Female Rats Lacking Dopamine Transporter. Biomedicines. vol 9. issue 2. 2021-03-16. PMID:33562738. |
disrupted dopamine (da) homeostasis, and more specifically dopamine transporter (dat) alterations, have been reported in a variety of psychiatric and neurodegenerative disorders. |
2021-03-16 |
2023-08-13 |
human |
| Luís Henrique Tieppo Fornari, Neivo da Silva Júnior, Camila Muratt Carpenedo, Arlete Hilbig, Carlos Roberto de Mello Riede. Striatal dopamine correlates to memory and attention in Parkinson's disease. American journal of nuclear medicine and molecular imaging. vol 11. issue 1. 2021-03-12. PMID:33688451. |
this study was designed to assess whether cognitive performances are related to dopamine active transporter (dat) availability in non-demented pd subjects. |
2021-03-12 |
2023-08-13 |
human |