| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Francesco Napolitano, Arianna De Rosa, Rosita Russo, Anna Di Maio, Martina Garofalo, Mauro Federici, Sara Migliarini, Ada Ledonne, Francesca Romana Rizzo, Luigi Avallone, Tommaso Nuzzo, Tommaso Biagini, Massimo Pasqualetti, Nicola Biagio Mercuri, Tommaso Mazza, Angela Chambery, Alessandro Usiell. The striatal-enriched protein Rhes is a critical modulator of cocaine-induced molecular and behavioral responses. Scientific reports. vol 9. issue 1. 2020-11-05. PMID:31653935. |
despite dramatic striatal alterations associated to cocaine exposure, our data did not reveal any significant changes in midbrain dopaminergic neurons as a lack of rhes did not affect: (i) dat activity; (ii) d2r-dependent regulation of girk; and (iii) d2r-dependent regulation of dopamine release. |
2020-11-05 |
2023-08-13 |
mouse |
| K Tecklenburg, A Forgács, I Apostolova, W Lehnert, S Klutmann, J Csirik, E Garutti, R Bucher. Performance evaluation of a novel multi-pinhole collimator for dopamine transporter SPECT. Physics in medicine and biology. vol 65. issue 16. 2020-11-05. PMID:32369781. |
this study evaluated a novel mph collimator specifically designed for dopamine transporter (dat) spect with a triple-head spect camera. |
2020-11-05 |
2023-08-13 |
Not clear |
| Alfonso Rubino, Claudio D'Addario, Martina Di Bartolomeo, Enrico Michele Salamone, Nicoletta Locuratolo, Francesco Fattapposta, Nicola Vanacore, Esterina Pascal. DNA methylation of the 5'-UTR DAT 1 gene in Parkinson's disease patients. Acta neurologica Scandinavica. vol 142. issue 3. 2020-11-05. PMID:32415851. |
among others, we, here, focused the attention on the dopamine transporter (dat) gene playing a critical role in maintaining the integrity of dopaminergic neurons. |
2020-11-05 |
2023-08-13 |
Not clear |
| Maria Bernarda Pitzianti, Simonetta Spiridigliozzi, Elisa Bartolucci, Susanna Esposito, Augusto Pasin. New Insights on the Effects of Methylphenidate in Attention Deficit Hyperactivity Disorder. Frontiers in psychiatry. vol 11. 2020-11-03. PMID:33132928. |
it addressed the following aspects: 1) mph effects on attention and executive functions in adhd; 2) the relation between mph efficacy and dopamine transporter gene (dat) polymorphism; and 3) the role of mph as an epigenetic modulator in adhd. |
2020-11-03 |
2023-08-13 |
human |
| Yang Hyun Lee, Jungho Cha, Seok Jong Chung, Han Soo Yoo, Young H Sohn, Byoung Seok Ye, Phil Hyu Le. Beneficial effect of estrogen on nigrostriatal dopaminergic neurons in drug-naïve postmenopausal Parkinson's disease. Scientific reports. vol 9. issue 1. 2020-11-02. PMID:31324895. |
we performed a comparative analysis of the striatal dopamine transporter (dat) availability between the two groups. |
2020-11-02 |
2023-08-13 |
Not clear |
| Hui Li, Yanlong Liu, Lifei Xing, Xiaoyu Yang, Jinzhong Xu, Qiushi Ren, Kuan-Pin Su, Yanye Lu, Fan Wan. Association of Cigarette Smoking with Sleep Disturbance and Neurotransmitters in Cerebrospinal Fluid. Nature and science of sleep. vol 12. 2020-10-31. PMID:33122957. |
dopamine transporter (dat) and serotonin transporter play a key role in the reuptake of da and 5-ht from the synaptic cleft into presynaptic neurons. |
2020-10-31 |
2023-08-13 |
human |
| Frederick Wasinski, João A B Pedroso, Willian O Dos Santos, Isadora C Furigo, David Garcia-Galiano, Carol F Elias, Edward O List, John J Kopchick, Raphael E Szawka, Jose Donat. Tyrosine Hydroxylase Neurons Regulate Growth Hormone Secretion via Short-Loop Negative Feedback. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 22. 2020-10-22. PMID:32317389. |
in contrast, ghr ablation in cells that express the dopamine transporter (dat) or dopamine β-hydroxylase (dbh; marker of noradrenergic/adrenergic cells) did not affect body growth. |
2020-10-22 |
2023-08-13 |
mouse |
| Zainab Mehkari, Lubna Mohammed, Moiz Javed, Aldanah Althwanay, Farah Ahsan, Federico Oliveri, Harshit K Goud, Ian H Rutkofsk. Manganese, a Likely Cause of 'Parkinson's in Cirrhosis', a Unique Clinical Entity of Acquired Hepatocerebral Degeneration. Cureus. vol 12. issue 9. 2020-10-20. PMID:33072457. |
from its influx to its effects on dopamine transporters (dat), where it disrupts dopamine homeostasis also altering postsynaptic dopamine (d2) receptors, it disrupts mitochondria and the endoplasmic reticulum (er) promotes oxidative stress and neuroinflammation. |
2020-10-20 |
2023-08-13 |
Not clear |
| Jeong-Yoon Lee, Soo Bin Park, Mina Lee, Hyunjin Ju, Kayeong Im, Kyum-Yil Kwo. Detailed visual assessment of striatal dopaminergic depletion in patients with idiopathic normal pressure hydrocephalus: unremarkable or not? BMC neurology. vol 20. issue 1. 2020-10-19. PMID:32652959. |
dopamine transporter (dat) imaging may enable clinicians to discriminate idiopathic normal pressure hydrocephalus (inph) from other parkinsonian disorders. |
2020-10-19 |
2023-08-13 |
Not clear |
| Zuhair I Abdulla, Bahar Pahlevani, Kerstin H Lundgren, Jordan L Pennington, Kenea C Udobi, Kim B Seroogy, Matthew R Skelto. Deletion of the Creatine Transporter (Slc6a8) in Dopaminergic Neurons Leads to Hyperactivity in Mice. Journal of molecular neuroscience : MN. vol 70. issue 1. 2020-10-08. PMID:31520365. |
the purpose of this study was to examine the effect of a loss of the slc6a8 (crt) gene in dopamine transporter (slc6a3; dat) expressing cells on locomotor activity and motor function as the mice age. |
2020-10-08 |
2023-08-13 |
mouse |
| Jijun Li, Yi Guo, Lin Zhao, Kexing Sun, Guangjun Xi, Zai-Wang L. Ningdong Granule Upregulates the Striatal DA Transporter and Attenuates Stereotyped Behavior of Tourette Syndrome in Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2020. 2020-10-03. PMID:33005197. |
the stereotyped behavior of the rats was recorded, the level of dopamine (da) in striatum, and the content of homovanillic acid (hva) in sera were tested, and dopamine transporter (dat) expression was measured in the study. |
2020-10-03 |
2023-08-13 |
rat |
| Evgeny A Budygin, Erik B Oleson, Yun Beom Lee, Lawrence C Blume, Michael J Bruno, Allyn C Howlett, Alexis C Thompson, Caroline E Bas. Acute Depletion of D2 Receptors from the Rat Substantia Nigra Alters Dopamine Kinetics in the Dorsal Striatum and Drug Responsivity. Frontiers in behavioral neuroscience. vol 10. 2020-10-01. PMID:28154530. |
analyses of dopamine (da) kinetics in the dstr reveal a decrease in da transporter (dat) function in the knockdown rats, an effect not observed in d2 autoreceptor knockout mouse models. |
2020-10-01 |
2023-08-13 |
mouse |
| Wolfgang G Bywalez, Tiffany Ona-Jodar, Michael Lukas, Jovica Ninkovic, Veronica Egge. Dendritic Arborization Patterns of Small Juxtaglomerular Cell Subtypes within the Rodent Olfactory Bulb. Frontiers in neuroanatomy. vol 10. 2020-10-01. PMID:28163674. |
dopaminergic neurons were identified in a transgenic mouse line where the expression of dopamine transporter (dat) was labeled with gfp. |
2020-10-01 |
2023-08-13 |
mouse |
| Ole V Mortensen, Mads B Larsen, Susan G Amar. MAP Kinase Phosphatase 3 (MKP3) Preserves Norepinephrine Transporter Activity by Modulating ERK1/2 Kinase-Mediated Gene Expression. Frontiers in cellular neuroscience. vol 11. 2020-10-01. PMID:28878626. |
previously we identified a map kinase phosphatase 3 (mkp3), as an important modulator of protein kinase c (pkc) mediated internalization of the related dopamine transporter (dat). |
2020-10-01 |
2023-08-13 |
Not clear |
| Agnieszka Nikiforuk, Predrag Kalaba, Marija Ilic, Volker Korz, Vladimir Dragačević, Judith Wackerlig, Thierry Langer, Harald Höger, Joanna Golebiowska, Piotr Popik, Gert Lube. A Novel Dopamine Transporter Inhibitor CE-123 Improves Cognitive Flexibility and Maintains Impulsivity in Healthy Male Rats. Frontiers in behavioral neuroscience. vol 11. 2020-10-01. PMID:29230168. |
drugs targeting the dopamine transporter (dat) are widely used for their potential to enhance cognitive abilities. |
2020-10-01 |
2023-08-13 |
human |
| Stefano Cinque, Francesca Zoratto, Anna Poleggi, Damiana Leo, Luca Cerniglia, Silvia Cimino, Renata Tambelli, Enrico Alleva, Raul R Gainetdinov, Giovanni Laviola, Walter Adrian. Behavioral Phenotyping of Dopamine Transporter Knockout Rats: Compulsive Traits, Motor Stereotypies, and Anhedonia. Frontiers in psychiatry. vol 9. 2020-10-01. PMID:29520239. |
dopamine transporter (dat) knockout (ko) and heterozygous (het) mice, in particular, have been widely used to study adhd. |
2020-10-01 |
2023-08-13 |
mouse |
| Jorge A Avila, Roseanna M Zanca, Denis Shor, Nicholas Paleologos, Amber A Alliger, Maria E Figueiredo-Pereira, Peter A Serran. Chronic voluntary oral methamphetamine induces deficits in spatial learning and hippocampal protein kinase Mzeta with enhanced astrogliosis and cyclooxygenase-2 levels. Heliyon. vol 4. issue 2. 2020-10-01. PMID:29560440. |
compared to controls, the voma paradigm also induced decreases in hippocampal levels of dopamine transporter (dat) and tyrosine hydroxylase (th), as well as increases in dopamine 1 receptor (d1r), glial fibrillary acidic protein (gfap) and cyclooxygenase-2 (cox-2), with a decrease in prostaglandins e2 (pge2) and d2 (pgd2). |
2020-10-01 |
2023-08-13 |
mouse |
| Kenneth J Nichols, Brandon Chen, Maria B Tomas, Christopher J Palestr. Interpreting European journal of hybrid imaging. vol 2. issue 1. 2020-10-01. PMID:29855627. |
interpreting dopamine transporter (dat) |
2020-10-01 |
2023-08-13 |
Not clear |
| Ambra Lanzo, Bryan D Safratowich, Sirisha R Kudumala, Ivan Gallotta, Giuseppina Zampi, Elia Di Schiavi, Lucia Carvell. Silencing of Frontiers in physiology. vol 9. 2020-10-01. PMID:29872404. |
silencing of the dopamine transporter (dat) is a cell membrane protein whose main function is to reuptake the dopamine (da) released in the synaptic cleft back into the dopaminergic neurons. |
2020-10-01 |
2023-08-13 |
Not clear |
| Rebecca Playne, Kathryn Jones, Bronwen Conno. Generation of dopamine neuronal-like cells from induced neural precursors derived from adult human cells by non-viral expression of lineage factors. Journal of stem cells & regenerative medicine. vol 14. issue 1. 2020-10-01. PMID:30018471. |
upon differentiation, inps gave rise to dopamine neuronal-like cells expressing tuj1, th, aadc, dat, vmat2 and girk2. |
2020-10-01 |
2023-08-13 |
human |