| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tatyana D Sotnikova, Evgeniya V Efimova, Raul R Gainetdino. Enhanced Dopamine Transmission and Hyperactivity in the Dopamine Transporter Heterozygous Mice Lacking the D3 Dopamine Receptor. International journal of molecular sciences. vol 21. issue 21. 2021-03-11. PMID:33153031. |
at the same time, heterozygous dat mice (dath) demonstrate a 2-fold increase in dopamine levels yet only a marginal elevation in locomotor activity level. |
2021-03-11 |
2023-08-13 |
mouse |
| Tatyana D Sotnikova, Evgeniya V Efimova, Raul R Gainetdino. Enhanced Dopamine Transmission and Hyperactivity in the Dopamine Transporter Heterozygous Mice Lacking the D3 Dopamine Receptor. International journal of molecular sciences. vol 21. issue 21. 2021-03-11. PMID:33153031. |
in the heterozygous dat mice, inactivation of the d3r gene (dath/d3k) resulted in significant hyperactivity and further elevation of striatal extracellular dopamine above levels observed in respective single mutant mice. |
2021-03-11 |
2023-08-13 |
mouse |
| Małgorzata Michałowska, Małgorzata Chalimoniuk, Ewa Jówko, Iwona Przybylska, Józef Langfort, Beata Toczylowska, Anna Krygowska-Wajs, Urszula Fisze. Gene polymorphisms and motor levodopa-induced complications in Parkinson's disease. Brain and behavior. vol 10. issue 3. 2021-03-09. PMID:32022467. |
the aim of the study was to evaluate the association of individual and combined single-nucleotide polymorphisms in brain-derived neurotrophic factor (bdnf), dopamine transporter (dat), and catechol-o-methyltransferase (comt) genes with the occurrence of motor levodopa-induced complications (mlic) in parkinson's disease (pd). |
2021-03-09 |
2023-08-13 |
Not clear |
| Aliaa Ghoneim, Christopher Pollard, Alok Tyagi, Ravi Jampan. Substantia nigra micro-haemorrhage causing ipsilateral unilateral Parkinsonism and abnormal dopamine transporter scan uptake. BJR case reports. vol 7. issue 1. 2021-02-23. PMID:33614119. |
presynaptic dopamine transporter (dat) single-photon emission computed tomography (spect) imaging is the most commonly used imaging technique in clinical practice to differentiate degenerative parkinson's disease (pd) and pd plus syndromes from other causes such as essential tremor and drug-induced parkinsonism. |
2021-02-23 |
2023-08-13 |
Not clear |
| Yeonghoon Son, Ye Ji Jeong, Na-Rae Shin, Se Jong Oh, Kyung Rok Nam, Hyung-Do Choi, Jae Yong Choi, Hae-June Le. Inhibition of Colony-Stimulating Factor 1 Receptor by PLX3397 Prevents Amyloid Beta Pathology and Rescues Dopaminergic Signaling in Aging 5xFAD Mice. International journal of molecular sciences. vol 21. issue 15. 2021-02-19. PMID:32756440. |
d2r, tyrosine hydroxylase (th), and dopamine transporter (dat) levels were analyzed in the brains of tg (5xfad) mice using immunohistochemistry. |
2021-02-19 |
2023-08-13 |
mouse |
| Julia Löser, Julia Luthardt, Michael Rullmann, David Weise, Osama Sabri, Jürgen Meixensberger, Swen Hesse, Dirk Winkle. Striatal dopamine transporter availability and individual clinical course within the 1-year follow-up of deep brain stimulation of the subthalamic nucleus in patients with Parkinson's disease. Journal of neurosurgery. 2021-02-19. PMID:33607613. |
yet the mechanism of action, especially the effects of stn-dbs on the availability of striatal dopamine transporter (dat) as a marker of nigrostriatal nerve cell function, remains largely unknown. |
2021-02-19 |
2023-08-13 |
Not clear |
| Muhammad O Chohan, Sari Esses, Julia Haft, Susanne E Ahmari, Jeremy Veenstra-VanderWeel. Altered baseline and amphetamine-mediated behavioral profiles in dopamine transporter Cre (DAT-Ires-Cre) mice compared to tyrosine hydroxylase Cre (TH-Cre) mice. Psychopharmacology. vol 237. issue 12. 2021-02-16. PMID:32778904. |
transgenic mouse lines expressing cre-recombinase under the regulation of either dopamine transporter (dat) or tyrosine hydroxylase (th) promoters are commonly used to study the dopamine (da) system. |
2021-02-16 |
2023-08-13 |
mouse |
| Ole Jensen, Muhammad Rafehi, Lukas Gebauer, Jürgen Brockmölle. Cellular Uptake of Psychostimulants - Are High- and Low-Affinity Organic Cation Transporters Drug Traffickers? Frontiers in pharmacology. vol 11. 2021-02-10. PMID:33551812. |
many of these are inhibitors of the presynaptic noradrenaline, dopamine, and serotonin transporters (net, dat, and sert). |
2021-02-10 |
2023-08-13 |
Not clear |
| Rafael Godoy, Khang Hua, Michael Kalyn, Victoria-Marie Cusson, Hymie Anisman, Marc Ekke. Dopaminergic neurons regenerate following chemogenetic ablation in the olfactory bulb of adult Zebrafish (Danio rerio). Scientific reports. vol 10. issue 1. 2021-02-09. PMID:32733000. |
we show here that treatment of transgenic tg(dat:cfp-ntr) adult zebrafish with the prodrug metronidazole (mtz) according to our administration regimen predominantly ablates dopamine (da) neurons within the olfactory bulb (ob) of adult fish. |
2021-02-09 |
2023-08-13 |
zebrafish |
| Tamara F Lundeen, Matthew Covington, Elizabeth A Krupinski, Ryan Avery, Hong Lei, Scott J Sherman, Phillip H Ku. Accuracy of Dopamine Transporter Imaging with Journal of nuclear medicine technology. vol 48. issue 2. 2021-02-08. PMID:31604897. |
this study examined the agreement between gold standard diagnosis and visual assessment of dopamine transporter (dat) imaging in hispanic and non-hispanic patients being evaluated for parkinsonian syndromes (ps). |
2021-02-08 |
2023-08-13 |
Not clear |
| Wei Yang, Adam C Munhall, Steven W Johnso. Dopamine Evokes a Trace Amine Receptor-dependent Inward Current that is Regulated by AMP Kinase in Substantia Nigra Dopamine Neurons. Neuroscience. vol 427. 2021-02-01. PMID:31883822. |
the present study examined the effect of ampk on current generated by dopamine, which unlike quinpirole, is a substrate for the dopamine transporter (dat). |
2021-02-01 |
2023-08-13 |
rat |
| Zachary D Brodnik, Wei Xu, Aashita Batra, Stacia I Lewandowski, Christina M Ruiz, Ole V Mortensen, Sandhya Kortagere, Stephen V Mahler, Rodrigo A Españ. Chemogenetic Manipulation of Dopamine Neurons Dictates Cocaine Potency at Distal Dopamine Transporters. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 45. 2021-02-01. PMID:33046544. |
the reinforcing efficacy of cocaine is largely determined by its capacity to inhibit the dopamine transporter (dat), and emerging evidence suggests that differences in cocaine potency are linked to several symptoms of cocaine use disorder. |
2021-02-01 |
2023-08-13 |
Not clear |
| Akanksha Mishra, Sairam Krishnamurth. Neurorestorative effects of sub-chronic administration of ambroxol in rodent model of Parkinson's disease. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 3. 2021-01-25. PMID:31654086. |
behavioral parameters were observed every week, and at last, tyrosine hydroxylase (th), dopamine transporter (dat), glucocerbrosidase (gcase) enzymatic and mitochondrial complex-i activity, α-synuclein levels, and nissl's staining were performed. |
2021-01-25 |
2023-08-13 |
rat |
| Manon Dubol, Christian Trichard, Claire Leroy, Bernard Granger, Eleni T Tzavara, Jean-Luc Martinot, Eric Artige. Lower midbrain dopamine transporter availability in depressed patients: Report from high-resolution PET imaging. Journal of affective disorders. vol 262. 2021-01-25. PMID:31732277. |
however, molecular imaging studies that assessed the dopamine transporter (dat) availability have led to inconsistent results, partly due to methodological considerations, and to exclusive focus on the striatum, precluding findings in extra-striatal regions. |
2021-01-25 |
2023-08-13 |
Not clear |
| Se Won Oh, Na-Young Shin, Uicheul Yoon, Intae Sin, Seung-Koo Le. Shared functional neural substrates in Parkinson's disease and drug-induced parkinsonism: association with dopaminergic depletion. Scientific reports. vol 10. issue 1. 2021-01-22. PMID:32669608. |
afterwards, we compared mean rsfmri values extracted from the overlapping areas with uptake quantitatively measured on dopamine transporter (dat) images and neuropsychological test results. |
2021-01-22 |
2023-08-13 |
Not clear |
| Ai-Xiao Chen, Jing-Jing Yan, Wen Zhang, Lei Wang, Zi-Xian Yu, Xiao-Jing Ding, Dan-Yang Wang, Min Zhang, Yan-Li Zhang, Nan Song, Zhuo-Lei Jiao, Chun Xu, Shu-Jia Zhu, Xiao-Hong X. Specific Hypothalamic Neurons Required for Sensing Conspecific Male Cues Relevant to Inter-male Aggression. Neuron. vol 108. issue 4. 2021-01-22. PMID:32961129. |
by in vivo recording of neuronal activities in behaving mice, we showed that neurons expressing dopamine transporter (dat |
2021-01-22 |
2023-08-13 |
mouse |
| John Hamilton, Sabrina Swenson, Andras Hajnal, Panayotis K Thano. Roux-en-Y gastric bypass surgery normalizes dopamine D1, D2, and DAT levels. Synapse (New York, N.Y.). 2021-01-14. PMID:29992624. |
roux-en-y gastric bypass surgery normalizes dopamine d1, d2, and dat levels. |
2021-01-14 |
2023-08-13 |
rat |
| J J van der Zande, M Joling, I G Happach, C Vriend, Ph Scheltens, J Booij, A W Lemstr. Serotonergic deficits in dementia with Lewy bodies with concomitant Alzheimer's disease pathology: An NeuroImage. Clinical. vol 25. 2021-01-11. PMID:31790878. |
serotonergic deficits in dementia with lewy bodies with concomitant alzheimer's disease pathology: an to study the influence of concomitant alzheimer's disease (ad) pathology in dementia with lewy bodies (dlb) on dopamine transporter (dat) and serotonin transporter (sert) availability, using |
2021-01-11 |
2023-08-13 |
Not clear |
| Noela Rodriguez-Losada, Rune Wendelbob, M Carmen Ocaña, Amelia Diaz Casares, Roberto Guzman de Villoría, Jose A Aguirre Gomez, Miguel A Arraez, Pedro Gonzalez-Alegre, Miguel A Medina, Ernest Arenas, Jose A Narvae. Graphene Oxide and Reduced Derivatives, as Powder or Film Scaffolds, Differentially Promote Dopaminergic Neuron Differentiation and Survival. Frontiers in neuroscience. vol 14. 2021-01-11. PMID:33408604. |
neuronal maturation of sn4741 in all go forms, and its derivatives were assessed by increased protein levels of tyrosine hydroxylase (th), dopamine transporter (dat), the glutamate inward rectifying potassium channel 2 (girk2), and of synaptic proteins, such as synaptobrevin and synaptophysin. |
2021-01-11 |
2023-08-13 |
mouse |
| Hirotaka Sekiguchi, Geoff Pavey, Brian Dea. Altered levels of dopamine transporter in the frontal pole and dorsal striatum in schizophrenia. NPJ schizophrenia. vol 5. issue 1. 2021-01-10. PMID:31792225. |
we postulated that the dopamine transporter (dat), which regulates intra-synaptic dopamine concentrations by transporting dopamine from the synaptic cleft into the pre-synaptic neuron, could be involved in dopaminergic dysfunction in schizophrenia. |
2021-01-10 |
2023-08-13 |
human |