| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maun-Yeng Alison Kok, Yu F. A new mouse tool for studying dopaminergic neurons. Journal of neuroscience methods. vol 347. 2021-06-21. PMID:33039413. |
here, we report a newly developed dat-ires-flp line, in which flippase gene is knocked in after the stop codon of slc6a3 (dopamine transporter, dat) gene. |
2021-06-21 |
2023-08-13 |
mouse |
| Shyh-Yuh Wei, Huai-Hsuan Tseng, Hui Hua Chang, Tsung-Hua Lu, Wei Hung Chang, Nan Tsing Chiu, Yen Kuang Yang, Po See Che. Dysregulation of oxytocin and dopamine in the corticostriatal circuitry in bipolar II disorder. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32788579. |
plasma oxt was measured and striatal dopamine transporter (dat) availability was assessed using [ |
2021-06-18 |
2023-08-13 |
Not clear |
| Daryl A Guthrie, Carmen Klein Herenbrink, Matthew Domenic Lycas, Therese Ku, Alessandro Bonifazi, Brian T DeVree, Signe Mathiasen, Jonathan A Javitch, Jonathan B Grimm, Luke Lavis, Ulrik Gether, Amy Hauck Newma. Novel Fluorescent Ligands Enable Single-Molecule Localization Microscopy of the Dopamine Transporter. ACS chemical neuroscience. vol 11. issue 20. 2021-06-18. PMID:32926777. |
the dopamine transporter (dat) is critical for spatiotemporal control of dopaminergic neurotransmission and is the target for therapeutic agents, including adhd medications, and abused substances, such as cocaine. |
2021-06-18 |
2023-08-13 |
Not clear |
| Charles Adeniran, Yaxia Yuan, Sarah E Davis, Ciai Lin, Jiahui Xu, Jun Zhu, Chang-Guo Zha. Binding Mode of Human Norepinephrine Transporter Interacting with HIV-1 Tat. ACS chemical neuroscience. vol 12. issue 9. 2021-06-18. PMID:33886267. |
hiv-infected patients have displayed increased synaptic levels of dopamine (da) due to reduced binding and function of monoamine transporters such as the norepinephrine transporter (net) and the dopamine transporter (dat). |
2021-06-18 |
2023-08-13 |
human |
| Genoveva Rojas, Ivana Orellana, Roberto Rosales-Rojas, Jennie García-Olivares, Jeffrey Comer, Ariela Vergara-Jaqu. Structural Determinants of the Dopamine Transporter Regulation Mediated by G Proteins. Journal of chemical information and modeling. vol 60. issue 7. 2021-06-17. PMID:32525311. |
dopamine clearance in the brain is controlled by the dopamine transporter (dat), a protein residing in the plasma membrane, which drives reuptake of extracellular dopamine into presynaptic neurons. |
2021-06-17 |
2023-08-13 |
Not clear |
| Liang Xu, Liao Y Che. Identification of a New Allosteric Binding Site for Cocaine in Dopamine Transporter. Journal of chemical information and modeling. vol 60. issue 8. 2021-06-17. PMID:32649824. |
dopamine (da) transporter (dat) is a major target for psychostimulant drugs of abuse such as cocaine that competitively binds to dat, inhibits da reuptake, and consequently increases synaptic da levels. |
2021-06-17 |
2023-08-13 |
Not clear |
| Chu-Ya Wu, I-Chen Hu, Yi-Chen Yang, Wei-Cheng Ding, Chih-Hsuan Lai, Yi-Zong Lee, Yi-Chung Liu, Hui-Chun Cheng, Ping-Chiang Ly. An essential role of acetyl coenzyme A in the catalytic cycle of insect arylalkylamine N-acetyltransferase. Communications biology. vol 3. issue 1. 2021-06-16. PMID:32796911. |
here, two ternary complexes of dopamine n-acetyltransferase (dat) before and after n-acetylation were solved at 1.28 Å and 1.36 Å resolution, respectively. |
2021-06-16 |
2023-08-13 |
Not clear |
| Yasunori Mito, Ichiro Yabe, Hiroaki Yaguchi, Chika Sato, Toshiki Takei, Satoshi Terae, Yasutaka Tajim. Relations of clinical symptoms with dopamine transporter imaging in drug-naïve Parkinson's disease. Clinical neurology and neurosurgery. vol 196. 2021-06-15. PMID:32593043. |
we examined the severity of motor symptoms and freezing of gait (fog), falls and overactive bladder (oab) in pd patients and their relations with striatal dopamine transporter (dat) binding. |
2021-06-15 |
2023-08-13 |
Not clear |
| Frederick Wasinski, Fernanda M Chaves, João A B Pedroso, Naira S Mansano, João Paulo Camporez, Daniela O Gusmão, Edward O List, John J Kopchick, Renata Frazão, Raphael E Szawka, Jose Donat. Growth hormone receptor in dopaminergic neurones regulates stress-induced prolactin release in male mice. Journal of neuroendocrinology. vol 33. issue 3. 2021-06-15. PMID:33769619. |
mice carrying specific deletion of gh receptor (ghr) in tyrosine hydroxylase (th)- or dopamine transporter (dat)-expressing cells were produced. |
2021-06-15 |
2023-08-13 |
mouse |
| Melinda Hersey, Amanda K Bacon, Lydia G Bailey, Mark A Coggiano, Amy H Newman, Lorenzo Leggio, Gianluigi Tand. Psychostimulant Use Disorder, an Unmet Therapeutic Goal: Can Modafinil Narrow the Gap? Frontiers in neuroscience. vol 15. 2021-06-15. PMID:34121988. |
the dopamine transporter (dat) is a common target of psychostimulant actions related to their use and dependence, and the recent availability of atypical dat inhibitors as a potential therapeutic option has garnered popularity in this research field. |
2021-06-15 |
2023-08-13 |
Not clear |
| Yasunori Mito, Ichiro Yabe, Hiroaki Yaguchi, Chika Sato, Toshiki Takei, Satoshi Terae, Yasutaka Tajim. Relationships of drooling with motor symptoms and dopamine transporter imaging in drug-naïve Parkinson's disease. Clinical neurology and neurosurgery. vol 195. 2021-06-14. PMID:32492588. |
we therefore examined the relationships of drooling with motor symptoms and striatal dopamine transporter (dat) binding measured by [123-iodine]-fluoropropyl-2beta-carbomethoxy-3beta-(4-iodophenylnortropane) dopamine transporter single-photon emission computed tomography( |
2021-06-14 |
2023-08-13 |
Not clear |
| Hiroki Moriya, Mikael Tiger, Amane Tateno, Takeshi Sakayori, Takahiro Masuoka, WooChan Kim, Ryosuke Arakawa, Yoshiro Okub. Low dopamine transporter binding in the nucleus accumbens in geriatric patients with severe depression. Psychiatry and clinical neurosciences. vol 74. issue 8. 2021-06-09. PMID:32363761. |
dopamine transporter (dat) is considered to reflect the function of the dopamine nerve system. |
2021-06-09 |
2023-08-13 |
Not clear |
| Juhee Lim, Hyo In Kim, Hyun Jin Cho. Regulation of dopaminergic neuronal phenotypes by the estrogen-related receptor gamma ligand GSK4716 via the activation of CREB signaling. Neurochemistry international. vol 136. 2021-06-07. PMID:32173553. |
our previous study showed the relevance of errγ in the regulation of the daergic neuronal phenotype with the upregulation of dopamine synthesizing tyrosine hydroxylase (th) and dopamine transporter (dat) and the possibility that errγ could be a novel target for regulating daergic neuronal differentiation. |
2021-06-07 |
2023-08-13 |
Not clear |
| Lorena Oliveira de Matos, Ana Luiza de Araujo Lima Reis, Lorena Terene Lopes Guerra, Leonardo de Oliveira Guarnieri, Muiara Aparecida Moraes, Laila Blanc Arabe, Renan Pedra de Souza, Grace Schenatto Pereira, Bruno Rezende Souz. Early postnatal l-Dopa treatment causes behavioral alterations in female vs. male young adult Swiss mice. Neuropharmacology. vol 170. 2021-06-03. PMID:32325324. |
knockout mice for dopamine transporters (dat) as well as site-specific knockout mice lacking dopaminergic d2 autoreceptors in dopaminergic neurons (da-d2rko) display behavioral alterations such as hyperlocomotion and abnormal prepulse inhibition. |
2021-06-03 |
2023-08-13 |
mouse |
| Navid Zeraatkar, Kesava S Kalluri, Benjamin Auer, Arda Konik, Timothy J Fromme, Lars R Furenlid, Phillip H Kuo, Michael A Kin. Investigation of Axial and Angular Sampling in Multi-Detector Pinhole-SPECT Brain Imaging. IEEE transactions on medical imaging. vol 39. issue 12. 2021-05-31. PMID:32763850. |
visual improvements for the brain phantoms with clinical distributions were less pronounced but presented quantitative improvements in the fidelity (normalized root-mean-square error (nrmse)) and striatal specific binding ratio (sbr) for a dopamine transporter (dat) distribution, and in nrmse and activity recovery for a brain perfusion distribution. |
2021-05-31 |
2023-08-13 |
Not clear |
| Yu Iwabuchi, Masashi Kameyama, Yohji Matsusaka, Hidetoshi Narimatsu, Masahiro Hashimoto, Morinobu Seki, Daisuke Ito, Hajime Tabuchi, Yoshitake Yamada, Masahiro Jinzak. A diagnostic strategy for Parkinsonian syndromes using quantitative indices of DAT SPECT and MIBG scintigraphy: an investigation using the classification and regression tree analysis. European journal of nuclear medicine and molecular imaging. vol 48. issue 6. 2021-05-28. PMID:33392714. |
we aimed to evaluate the diagnostic performances of quantitative indices obtained from dopamine transporter (dat) single-photon emission computed tomography (spect) and |
2021-05-28 |
2023-08-13 |
Not clear |
| Seunghyeon Shin, Keunyoung Kim, Kyoungjune Pak, Hyun-Yeol Nam, Hyung-Jun Im, Myung Jun Lee, Seong-Jang Kim, In Joo Ki. Effects of animal handling on striatal DAT availability in rats. Annals of nuclear medicine. vol 34. issue 7. 2021-05-27. PMID:32424547. |
we aimed to evaluate the effects of anesthesia and fasting of rats in dopamine transporter (dat) imaging acquisition. |
2021-05-27 |
2023-08-13 |
rat |
| Silvia Cerantola, Valentina Caputi, Gabriella Contarini, Maddalena Mereu, Antonella Bertazzo, Annalisa Bosi, Davide Banfi, Dante Mantini, Cristina Giaroni, Maria Cecilia Giro. Dopamine Transporter Genetic Reduction Induces Morpho-Functional Changes in the Enteric Nervous System. Biomedicines. vol 9. issue 5. 2021-05-27. PMID:33923250. |
since dopamine transporter (dat) is involved in several brain disorders by modulating extracellular dopamine in the central nervous system, this study evaluated the impact of dat genetic reduction on the morpho-functional integrity of mouse small intestine enteric nervous system (ens). |
2021-05-27 |
2023-08-13 |
mouse |
| Amine Bah. Dopamine transporter gene expression within the nucleus accumbens plays important role in the acquisition and reinstatement of ethanol-seeking behavior in mice. Behavioural brain research. vol 381. 2021-05-26. PMID:31923430. |
in a previous study we showed that the dopamine transporter (dat) is implicated in voluntary intake and preference. |
2021-05-26 |
2023-08-13 |
mouse |
| JoLynn B Giancola, Alessandro Bonifazi, Jianjing Cao, Therese Ku, Alexandra J Haraczy, Jenny Lam, Rana Rais, Mark A Coggiano, Gianluigi Tanda, Amy Hauck Newma. Structure-activity relationships for a series of (Bis(4-fluorophenyl)methyl)sulfinylethyl-aminopiperidines and -piperidine amines at the dopamine transporter: Bioisosteric replacement of the piperazine improves metabolic stability. European journal of medicinal chemistry. vol 208. 2021-05-26. PMID:32947229. |
atypical dopamine transporter (dat) inhibitors, based on (±)modafinil, have shown therapeutic potential in preclinical models of psychostimulant abuse. |
2021-05-26 |
2023-08-13 |
rat |