| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Danusio Pinheiro Sartori, N F Oliveira, José Tiago Valentim, D M A Silva, A S V Mallman, I C M Oliveira, R C Chaves, V C Capibaribe, A M R Carvalho, M O Rebouças, Danielle Silveira Macedo, Adriano José Maia Chaves Filho, M M F Fonteles, S J C Gutierrez, José Maria Barbosa-Filho, Melina Mottin, Carolina Horta Andrade, F C F Sous. Involvement of monoaminergic targets in the antidepressant- and anxiolytic-like effects of the synthetic alkamide riparin IV: Elucidation of further mechanisms through pharmacological, neurochemistry and computational approaches. Behavioural brain research. vol 383. 2021-05-25. PMID:31987932. |
molecular docking demonstrated favorable binding conformation and affinity of ripiv to monoamine oxidase b (mao-b), serotonin transporter (sert), α1 receptor, d2 receptor, dopamine transporter (dat) and at some extent gaba-a receptor. |
2021-05-25 |
2023-08-13 |
mouse |
| Kyoungjune Pak, Seongho Seo, Keunyoung Kim, Myung Jun Lee, Myung Jun Shin, Sunghwan Suh, Hyung-Jun Im, Jung-Jun Park, Seong-Jang Kim, In Joo Ki. Striatal dopamine transporter changes after glucose loading in humans. Diabetes, obesity & metabolism. vol 22. issue 1. 2021-05-20. PMID:31478329. |
the dopamine transporter (dat) actively translocates dopamine that is released from the presynaptic neurons across the membranes of nerve terminals into the extracellular space. |
2021-05-20 |
2023-08-13 |
Not clear |
| Michelly Arjona, Juliana M P Toldo, Natalia Carvalho Queiroz, Jose Luiz Pedroso, Guilherme de Carvalho Campos Neto, Orlando G P Barsottini, Andre C Felici. A Real-World Study of Cerebral 99mTc-TRODAT-1 Single-Photon Emission Computed Tomography (SPECT) Imaging of the Dopamine Transporter in Patients with Parkinson Disease from a Tertiary Hospital in Brazil. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-05-20. PMID:33361743. |
background studies on the routine clinical use of dopamine transporter (dat) imaging have largely been conducted in europe and the united states. |
2021-05-20 |
2023-08-13 |
Not clear |
| Fabiana Festucci, Clelia Buccheri, Anna Parvopassu, Maurizio Oggiano, Marco Bortolato, Giovanni Laviola, Giuseppe Curcio, Walter Adrian. "Himalayan Bridge": A New Unstable Suspended Bridge to Investigate Rodents' Venturesome Behavior. Frontiers in behavioral neuroscience. vol 15. 2021-05-18. PMID:33994967. |
thus, 24 wild-type (wt) subjects were divided into three different housing groups: wt rats grown up with wt adult rats; control wt adolescent rats (grown up with wt adolescents), which showed a proclivity to risk; and wt rats grown up with an adult rat harboring a truncated mutation for their dopamine transporter (dat). |
2021-05-18 |
2023-08-13 |
mouse |
| Aline Delva, Donatienne Van Weehaeghe, June van Aalst, Jenny Ceccarini, Michel Koole, Kristof Baete, Johan Nuyts, Wim Vandenberghe, Koen Van Laer. Quantification and discriminative power of European journal of nuclear medicine and molecular imaging. vol 47. issue 8. 2021-05-14. PMID:31776633. |
quantification and discriminative power of dopamine transporter (dat) imaging is an important adjunct in the diagnostic workup of patients with parkinsonism. |
2021-05-14 |
2023-08-13 |
Not clear |
| Vasko Kramer, Carlos Juri, Patrick J Riss, Rossana Pruzzo, Cristian Soza-Ried, Jonathan Flores, Ana Hurtado, Frank Rösch, Pedro Chana-Cuevas, Horacio Amara. Pharmacokinetic evaluation of [ European journal of nuclear medicine and molecular imaging. vol 47. issue 8. 2021-05-14. PMID:31788709. |
pharmacokinetic evaluation of [ dopamine transporters (dat) modulate pre-synaptic dopamine and physiological functions such as movement and reward. |
2021-05-14 |
2023-08-13 |
Not clear |
| Cristiana Carbone, Anna Brancato, Annalisa Adinolfi, Sara Lucia Maria Lo Russo, Enrico Alleva, Carla Cannizzaro, Walter Adrian. Motor Transitions' Peculiarity of Heterozygous DAT Rats When Offspring of an Unconventional KOxWT Mating. Neuroscience. vol 433. 2021-05-14. PMID:32171819. |
mat-het rats displayed region-specific changes in dat expression, compared to "classical" mix-het subjects: greater dat availability may elevate threshold for dopamine action. |
2021-05-14 |
2023-08-13 |
human |
| Yaoyu Pu, Lijia Chang, Youge Qu, Siming Wang, Yunfei Tan, Xingming Wang, Jiancheng Zhang, Kenji Hashimot. Glyphosate exposure exacerbates the dopaminergic neurotoxicity in the mouse brain after repeated administration of MPTP. Neuroscience letters. vol 730. 2021-05-14. PMID:32387710. |
in this study, we examined whether the exposure of glyphosate can affect the reduction of dopamine transporter (dat) in the striatum and tyrosine hydroxylase (th) in the substantial nigra (snr) of mouse brain after repeated administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp). |
2021-05-14 |
2023-08-13 |
mouse |
| Mike Jeon, Guanyou Lin, Zachary R Stephen, Josey E Vechey, Manjot Singh, Richard Revia, Amy Hauck Newman, Diana Martinez, Miqin Zhan. Cocaine analogue conjugated magnetic nanoparticles for labeling and imaging dopaminergic neurons. Biomaterials science. vol 8. issue 15. 2021-05-14. PMID:32515443. |
molecular imaging of the dopamine transporter (dat) with positron emission tomography (pet) or single photon emission computed tomography (spect) has been widely used in studies of neurological and psychiatric disorders. |
2021-05-14 |
2023-08-13 |
Not clear |
| Greer McKendrick, Sonakshi Sharma, Dongxiao Sun, Patrick A Randall, Nicholas M Grazian. Acute and chronic bupropion treatment does not prevent morphine-induced conditioned place preference in mice. European journal of pharmacology. vol 889. 2021-05-14. PMID:33039460. |
therefore, we investigated whether use of an fda-approved drug, bupropion, an inhibitor of the dopamine transporter (dat), or a dopamine uptake inhibitor with high affinity for dat, jhw 007, was able to decrease preference for a drug-paired context. |
2021-05-14 |
2023-08-13 |
mouse |
| Maged M Harraz, Prasun Guha, In Guk Kang, Evan R Semenza, Adarsha P Malla, Young Jun Song, Luke Reilly, Isaac Treisman, Pedro Cortés, Mark A Coggiano, Vijayabhaskar Veeravalli, Rana Rais, Gianluigi Tanda, Solomon H Snyde. Cocaine-induced locomotor stimulation involves autophagic degradation of the dopamine transporter. Molecular psychiatry. vol 26. issue 2. 2021-05-14. PMID:33414501. |
this action is thought to reflect binding of cocaine to the dopamine transporter (dat) to inhibit its function. |
2021-05-14 |
2023-08-13 |
mouse |
| Neda Yazdanfar, Seyed Ali Mard, Javad Mahmoudi, Nima Bakhtiari, Alireza Sarkaki, Alireza Farna. Maternal Morphine Exposure and Post-Weaning Social Isolation Impair Memory and Ventral Striatum Dopamine System in Male Offspring: Is an Enriched Environment Beneficial? Neuroscience. vol 461. 2021-05-14. PMID:33662528. |
moreover, the ventral striatum dopamine's content (da), mrna expressions of dopamine receptor 1(d1r) and dopamine receptor 2 (d2r), and dopamine transporter (dat) were evaluated. |
2021-05-14 |
2023-08-13 |
rat |
| Iwona Ruchala, Umberto M Battisti, Vy T Nguyen, Rita Yu-Tzu Chen, Richard A Glennon, Jose M Elti. Functional characterization of N-octyl 4-methylamphetamine variants and related bivalent compounds at the dopamine and serotonin transporters using Ca Toxicology and applied pharmacology. vol 419. 2021-05-11. PMID:33785354. |
functional characterization of n-octyl 4-methylamphetamine variants and related bivalent compounds at the dopamine and serotonin transporters using ca the early characterization of ligands at the dopamine and serotonin transporters, dat and sert, respectively, is important for drug discovery, forensic sciences, and drug abuse research. |
2021-05-11 |
2023-08-13 |
Not clear |
| Tomoyuki Miyamoto, Masayuki Miyamoto, Kyoko Numahata, Hiroyuki Onoue, Yasuhisa Akaiwa, Toshimi Sairench. Reduced dopamine transporter binding predicts early transition to Lewy body disease in Japanese patients with idiopathic rapid eye movement sleep behavior disorder. Journal of the neurological sciences. vol 414. 2021-05-10. PMID:32330698. |
we examined dopamine transporter (dat) binding in japanese patients with idiopathic rapid eye movement sleep behavior disorder (irbd) as a biomarker for the development of lewy body disease (lbd). |
2021-05-10 |
2023-08-13 |
Not clear |
| Sarah Threlfell, Amir Saeid Mohammadi, Brent J Ryan, Natalie Connor-Robson, Nicola J Platt, Rishi Anand, Florence Serres, Trevor Sharp, Nora Bengoa-Vergniory, Richard Wade-Martins, Andrew Ewing, Stephanie J Cragg, Katherine R Brimblecomb. Striatal Dopamine Transporter Function Is Facilitated by Converging Biology of α-Synuclein and Cholesterol. Frontiers in cellular neuroscience. vol 15. 2021-05-04. PMID:33935654. |
striatal dopamine transporters (dat) powerfully regulate dopamine signaling, and can contribute risk to degeneration in parkinson's disease (pd). |
2021-05-04 |
2023-08-13 |
Not clear |
| Sarah Threlfell, Amir Saeid Mohammadi, Brent J Ryan, Natalie Connor-Robson, Nicola J Platt, Rishi Anand, Florence Serres, Trevor Sharp, Nora Bengoa-Vergniory, Richard Wade-Martins, Andrew Ewing, Stephanie J Cragg, Katherine R Brimblecomb. Striatal Dopamine Transporter Function Is Facilitated by Converging Biology of α-Synuclein and Cholesterol. Frontiers in cellular neuroscience. vol 15. 2021-05-04. PMID:33935654. |
here, we tested whether dat function in governing dopamine (da) uptake and release is modified in a human-α-synuclein-overexpressing ( |
2021-05-04 |
2023-08-13 |
Not clear |
| Nurul M Abdul Satar, Satoshi Ogawa, Ishwar S Parha. Kisspeptin-1 regulates forebrain dopaminergic neurons in the zebrafish. Scientific reports. vol 10. issue 1. 2021-04-30. PMID:33168887. |
in this study, to investigate whether habenular kiss1 regulates fear responses via dopamine neurons in the zebrafish, kiss1 peptides were intracranially administered close to the habenula, and the expression of dopamine-related genes (th1, th2 and dat) were examined in the brain using real-time pcr and dopamine levels using lc-ms/ms. |
2021-04-30 |
2023-08-13 |
zebrafish |
| Madeline M Pantoni, Stephanie A Carmack, Leen Hammam, Stephan G Anagnostara. Dopamine and norepinephrine transporter inhibition for long-term fear memory enhancement. Behavioural brain research. vol 378. 2021-04-29. PMID:31580915. |
while psychostimulants likely exert their rewarding and addictive properties through dopamine transporter (dat) inhibition, the mechanisms of their procognitive effects are less certain. |
2021-04-29 |
2023-08-13 |
mouse |
| Suzanne M Underhill, Susan G Amar. Acetylcholine Receptor Stimulation Activates Protein Kinase C Mediated Internalization of the Dopamine Transporter. Frontiers in cellular neuroscience. vol 15. 2021-04-28. PMID:33897375. |
the dopamine transporter (dat) clears neurotransmitters from the extracellular space and serves as an important regulator of signal amplitude and duration at sites of dopamine release. |
2021-04-28 |
2023-08-13 |
Not clear |
| Suzanne M Underhill, Susan G Amar. Acetylcholine Receptor Stimulation Activates Protein Kinase C Mediated Internalization of the Dopamine Transporter. Frontiers in cellular neuroscience. vol 15. 2021-04-28. PMID:33897375. |
acute activation of protein kinase c (pkc) by phorbol esters facilitates clathrin-dependent internalization of the dat in a variety of model systems; however, the physiological stimuli and cell-surface receptor systems that activate pkc and regulate the dat in dopamine neurons remain elusive. |
2021-04-28 |
2023-08-13 |
Not clear |