All Relations between dopamine and dat

Publication Sentence Publish Date Extraction Date Species
Andreas-Antonios Roussakis, Marta Gennaro, Nicholas P Lao-Kaim, David Towey, Paola Piccin. Dopamine Transporter Density in Journal of neuroinflammation and neurodegenerative diseases. vol 3. issue 1. 2021-01-10. PMID:31819926. this study examines whether dopamine transporter (dat)-specific spect imaging in 2021-01-10 2023-08-13 Not clear
Alison D Kreisler, Michael J Terranova, Sucharita S Somkuwar, Dvijen C Purohit, Shanshan Wang, Brian P Head, Chitra D Mandya. In vivo reduction of striatal D1R by RNA interference alters expression of D1R signaling-related proteins and enhances methamphetamine addiction in male rats. Brain structure & function. vol 225. issue 3. 2021-01-08. PMID:32246242. d1rshrna reduced the expression of psd-95 and mapk-1 and increased the expression of dopamine transporter (dat) in the ds from methamphetamine, but not sucrose rats. 2021-01-08 2023-08-13 rat
Jian Huang, Genmeng Yang, Zhen Li, Chi-Kwan Leung, Wenguang Wang, Yuanyuan Li, Liu Liu, Baoyu Shen, Cuihua He, Yongwang He, Xiaofeng Zeng, Juan L. Involvement of dopamine D3 receptor and dopamine transporter in methamphetamine-induced behavioral sensitization in tree shrews. Brain and behavior. vol 10. issue 2. 2021-01-04. PMID:31943832. this study aims to establish a methamphetamine (meth)-induced behavioral sensitization model using tree shrews, as well as to measure the protein expression of the dopamine d3 receptor (d3r) and dopamine transporter (dat). 2021-01-04 2023-08-13 Not clear
Catherine F Moore, Michael Z Leonard, Nicholas M Micovic, Klaus A Miczek, Valentina Sabino, Pietro Cotton. Reward sensitivity deficits in a rat model of compulsive eating behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 4. 2020-12-28. PMID:31622973. we then quantified da release in the nucleus accumbens (nac) shell after treatment with d-amphetamine using in vivo microdialysis, quantified levels of tyrosine hydroxylase (th) and dopamine transporter (dat) mrna using quantitative polymerase chain reaction (qpcr), and lastly, quantified baseline extracellular da and function of dat in vivo using quantitative "no-net-flux" microdialysis. 2020-12-28 2023-08-13 rat
Dirleise Colle, Danúbia Bonfanti Santos, Aline Aita Naime, Cinara Ludvig Gonçalves, Heloisa Ghizoni, Mariana Appel Hort, Marcelo Farin. Early Postnatal Exposure to Paraquat and Maneb in Mice Increases Nigrostriatal Dopaminergic Susceptibility to a Re-challenge with the Same Pesticides at Adulthood: Implications for Parkinson's Disease. Neurotoxicity research. vol 37. issue 1. 2020-12-21. PMID:31422567. however, pn pesticides exposure decreased the number of tyrosine hydroxylase (th)- and dopamine transporter (dat)-positive neurons in the substantia nigra pars compacta (snpc), as well as reduced th and dat immunoreactivity in the striatum. 2020-12-21 2023-08-13 mouse
Rita R Fagan, Patrick J Kearney, Carolyn G Sweeney, Dino Luethi, Florianne E Schoot Uiterkamp, Klaus Schicker, Brian S Alejandro, Lauren C O'Connor, Harald H Sitte, Haley E Melikia. Dopamine transporter trafficking and Rit2 GTPase: Mechanism of action and The Journal of biological chemistry. vol 295. issue 16. 2020-12-17. PMID:32132171. dopamine transporter trafficking and rit2 gtpase: mechanism of action and following its evoked release, dopamine (da) signaling is rapidly terminated by presynaptic reuptake, mediated by the cocaine-sensitive da transporter (dat). 2020-12-17 2023-08-13 Not clear
Jung Hwan Shin, Jee-Young Lee, Yu-Kyeong Kim, Sung-A Shin, Heejung Kim, Hyunwoo Nam, Beomseok Jeo. Longitudinal change in dopamine transporter availability in idiopathic REM sleep behavior disorder. Neurology. vol 95. issue 23. 2020-12-15. PMID:32989104. to elucidate longitudinal changes in the dopamine transporter (dat) availability in association with the prodromal markers in idiopathic rem sleep behavior disorder (irbd), we analyzed a longitudinal prospective irbd cohort data. 2020-12-15 2023-08-13 Not clear
Xuran Li, Weiwei Yang, Xin Li, Min Chen, Chengwei Liu, Jie Li, Shun Y. Alpha-synuclein oligomerization and dopaminergic degeneration occur synchronously in the brain and colon of MPTP-intoxicated parkinsonian monkeys. Neuroscience letters. vol 716. 2020-12-14. PMID:31759083. here, in mptp-intoxicated cynomolgus monkeys, we showed a parallel daergic degeneration in the colon as well as in the substantia nigra and striatum (sn/str), as indicated by reduced expression of tyrosine hydroxylase (th) and dopamine transporter (dat). 2020-12-14 2023-08-13 human
M F Rossetti, R Schumacher, M P Gastiazoro, G P Lazzarino, M F Andreoli, C Stoker, J Varayoud, J G Ramo. Epigenetic Dysregulation of Dopaminergic System by Maternal Cafeteria Diet During Early Postnatal Development. Neuroscience. vol 424. 2020-12-10. PMID:31682820. at pnd10, maternal caf diet decreased the transcription of th, ghsr, drd2 and dopamine transporter (dat) in vta. 2020-12-10 2023-08-13 rat
Molly A Kwiatkowski, Zackary A Cope, Maria L Lavadia, Chuck J A van de Cappelle, Davide Dulcis, Jared W Youn. Short-active photoperiod gestation induces psychiatry-relevant behavior in healthy mice but a resiliency to such effects are seen in mice with reduced dopamine transporter expression. Scientific reports. vol 10. issue 1. 2020-12-07. PMID:32576854. a dysfunctional dopamine system is implicated in most psychiatric disorders, and genetic polymorphisms reducing expression of the dopamine transporter (dat) are associated with some conditions. 2020-12-07 2023-08-13 mouse
Han Soo Yoo, Jun Sung Lee, Seok Jong Chung, Byoung Seok Ye, Young H Sohn, Seung-Jae Lee, Phil Hyu Le. Changes in plasma arylsulfatase A level as a compensatory biomarker of early Parkinson's disease. Scientific reports. vol 10. issue 1. 2020-11-30. PMID:32221382. we compared the plasma arsa level among the groups and assessed its correlation to clinical parameters and striatal dopamine transporter (dat) activity. 2020-11-30 2023-08-13 Not clear
Takahiro Masuoka, Amane Tateno, Takeshi Sakayori, Mikael Tiger, WooChan Kim, Hiroki Moriya, Satoshi Ueda, Ryosuke Arakawa, Yoshiro Okub. Electroconvulsive therapy decreases striatal dopamine transporter binding in patients with depression: A positron emission tomography study with [ Psychiatry research. Neuroimaging. vol 301. 2020-11-30. PMID:32464340. since dopamine transporters (dat) regulate extracellular dopamine concentration, dat represents an interesting target for the study of the mechanism of action of ect. 2020-11-30 2023-08-13 Not clear
Eva Martinez, Benjamin Pasquereau, Guillaume Drui, Yosuke Saga, Élise Météreau, Léon Trembla. Ventral striatum supports Methylphenidate therapeutic effects on impulsive choices expressed in temporal discounting task. Scientific reports. vol 10. issue 1. 2020-11-25. PMID:31959838. methylphenidate (mph) is a dopamine transporter (dat) inhibitor used to treat attention-deficit/hyperactivity-disorder (adhd). 2020-11-25 2023-08-13 monkey
Han Soo Yoo, Sangwon Lee, Seok Jong Chung, Byoung Seok Ye, Young H Sohn, Mijin Yun, Phil Hyu Le. Clinical and Striatal Dopamine Transporter Predictors of Mild Behavioral Impairment in Drug-Naive Parkinson Disease. Clinical nuclear medicine. vol 45. issue 11. 2020-11-25. PMID:32956117. we explored mild behavioral impairment (mbi) in drug-naive patients with pd and its clinical and dopamine transporter (dat) correlates. 2020-11-25 2023-08-13 Not clear
Domen Pregeljc, Diana Teodorescu-Perijoc, Robert Vianello, Nejc Umek, Janez Mavr. How Important Is the Use of Cocaine and Amphetamines in the Development of Parkinson Disease? A Computational Study. Neurotoxicity research. vol 37. issue 3. 2020-11-20. PMID:31828739. by considering three transport pathways (dopamine transporter (dat), vesicular transporter (vt), and exocytosis), four simulated scenarios were investigated: homeostasis, application of cocaine, methamphetamine, and reserpine. 2020-11-20 2023-08-13 human
Domen Pregeljc, Diana Teodorescu-Perijoc, Robert Vianello, Nejc Umek, Janez Mavr. How Important Is the Use of Cocaine and Amphetamines in the Development of Parkinson Disease? A Computational Study. Neurotoxicity research. vol 37. issue 3. 2020-11-20. PMID:31828739. accordingly, our study suggests that amphetamines and other substances that block vt, but not cocaine or substances that only block dat, may be etiologically important in the cytosolic dopamine mediation of neurodegeneration in parkinson disease/parkinsonism. 2020-11-20 2023-08-13 human
Ying Chun Tai, Mei Hung Chi, Ching-Lin Chu, Nan Tsing Chiu, Wei Jen Yao, Po See Chen, Yen Kuang Yan. Availability of Striatal Dopamine Transporter in Healthy Individuals With and Without a Family History of ADHD. Journal of attention disorders. vol 23. issue 7. 2020-11-18. PMID:27401239. abnormal dopamine transporter (dat) availability has been reported, but the data are inconsistent. 2020-11-18 2023-08-13 Not clear
Charlotte P Magee, Christopher L German, Yasmeen H Siripathane, Peter S Curtis, David J Anderson, Diana G Wilkins, Glen R Hanson, Annette E Fleckenstei. 3,4-Methylenedioxypyrovalerone: Neuropharmacological Impact of a Designer Stimulant of Abuse on Monoamine Transporters. The Journal of pharmacology and experimental therapeutics. vol 374. issue 2. 2020-11-12. PMID:32385092. because the dopamine (da) transporter (dat) and vesicular monoamine transporter-2 (vmat-2) are key regulators of both the abuse and neurotoxic potential of structurally and behaviorally related agents, the impact of mdpv on these transporters was investigated. 2020-11-12 2023-08-13 rat
Peter Owen Jenkins, Andreas-Antonios Roussakis, Sara De Simoni, Niall Bourke, Jessica Fleminger, James Cole, Paola Piccini, David Shar. Distinct dopaminergic abnormalities in traumatic brain injury and Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry. vol 91. issue 6. 2020-11-09. PMID:32381639. we test whether tbi, pd and rbd have distinct striatal dopamine abnormalities using dopamine transporter (dat) imaging. 2020-11-09 2023-08-13 Not clear
Rafieh Alizadeh, Farnaz Ramezanpour, Amirhossein Mohammadi, Mina Eftekharzadeh, Sara Simorgh, Milad Kazemiha, Fatemeh Morad. Differentiation of human olfactory system-derived stem cells into dopaminergic neuron-like cells: A comparison between olfactory bulb and mucosa as two sources of stem cells. Journal of cellular biochemistry. vol 120. issue 12. 2020-11-05. PMID:31297865. quantitative real-time polymerase chain reaction analysis 3 weeks after induction demonstrated that the mrna expression of the dopaminergic activity markers tyrosine hydroxylase (th), dopamine transporter (dat), paired box gene 2 (pax2), and pax5 in the neuron-like cells derived from ob-nscs was significantly higher than those derived from oe-mscs. 2020-11-05 2023-08-13 human