| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' A Wasynczuk, A Kirksey, D M Morr\\xc3\\xa. Effects of maternal vitamin B-6 deficiency on specific regions of developing rat brain: the extrapyramidal motor system. The Journal of nutrition. vol 113. issue 4. 1983-05-27. PMID:6834147.' |
in this study concentrations of the neurotransmitters, gamma-aminobutyric acid (gaba) and dopamine (da) and certain amino acids were determined in substantia nigra (sn) and caudate/putamen (c/p) in progeny of dams fed diets containing either deficient (d), 0.6 or control (c), 7.0 mg pyridoxine x hcl (pn x hcl) per kilogram diet throughout growth, gestation and lactation. |
1983-05-27 |
2023-08-12 |
rat |
| A R Cools, R Jaspers, W Kolasiewicz, K H Sontag, S Wolfart. Substantia nigra as a station that not only transmits, but also transforms, incoming signals for its behavioural expression: striatal dopamine and GABA-mediated responses of pars reticulata neurons. Behavioural brain research. vol 7. issue 1. 1983-04-07. PMID:6297521. |
substantia nigra as a station that not only transmits, but also transforms, incoming signals for its behavioural expression: striatal dopamine and gaba-mediated responses of pars reticulata neurons. |
1983-04-07 |
2023-08-12 |
Not clear |
| J Donaldson, D McGregor, F LaBell. Manganese neurotoxicity: a model for free radical mediated neurodegeneration? Canadian journal of physiology and pharmacology. vol 60. issue 11. 1983-03-11. PMID:6129921. |
this latter effect may arise preferentially in the substantia nigra, where neuromelanin is formed nonenzymatically by autoxidation of dopamine. |
1983-03-11 |
2023-08-12 |
rat |
| R S Jones, A V Juorio, A A Boulto. Changes in levels of dopamine and tyramine in the rat caudate nucleus following alterations in impulse flow in the nigrostriatal pathway. Journal of neurochemistry. vol 40. issue 2. 1983-03-11. PMID:6130125. |
following electric stimulation of the substantia nigra for 1 h there was a substantial increase in dopamine (da) turnover in the rat caudate nucleus evidenced by an increase in its acid metabolite homovanillic acid (hva). |
1983-03-11 |
2023-08-12 |
rat |
| M F Chesselet, T D Reisin. Somatostatin regulates dopamine release in rat striatal slices and cat caudate nuclei. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 3. issue 1. 1983-03-11. PMID:6130131. |
no changes in tritiated dopamine were seen in either substantia nigra during or after the peptide's application in the caudate nucleus. |
1983-03-11 |
2023-08-12 |
rat |
| P L Wood, J W Richar. Morphine and nigrostriatal function in the rat and mouse: the role of nigral and striatal opiate receptors. Neuropharmacology. vol 21. issue 12. 1983-03-11. PMID:6296716. |
in the mouse, morphine acted at the level of the substantia nigra to enhance both striatal dopamine synthesis and release. |
1983-03-11 |
2023-08-12 |
mouse |
| J P Fry, D F Sharman, D B Stephen. Cerebral dopamine, apomorphine and oral activity in the neonatal pig. Journal of veterinary pharmacology and therapeutics. vol 4. issue 3. 1983-03-11. PMID:7349334. |
these observations revealed that the increased non-nutritive oral activity of such piglets did not appear to be caused by an increased release of dopamine in the brain, since it was not associated with increases in the concentrations of the acidic metabolites of dopamine in either the caudate nucleus, the putamen, the nucleus accumbens, the olfactory tubercle, the hypothalamus, or the substantia nigra. |
1983-03-11 |
2023-08-12 |
Not clear |
| W H Oertel, M L Tappaz, A Berod, E Mugnain. Two-color immunohistochemistry for dopamine and GABA neurons in rat substantia nigra and zona incerta. Brain research bulletin. vol 9. issue 1-6. 1983-02-25. PMID:6129046. |
two-color immunohistochemistry for dopamine and gaba neurons in rat substantia nigra and zona incerta. |
1983-02-25 |
2023-08-12 |
rat |
| J G Woo. Electron microscopic cytochemical correlates of histofluorescence. Brain research bulletin. vol 9. issue 1-6. 1983-02-25. PMID:7172026. |
the biogenic amines, norepinephrine and dopamine, have been localized electron microscopically in the substantia nigra, pineal body, adrenal medulla and stellate ganglion of squirrel monkeys. |
1983-02-25 |
2023-08-12 |
monkey |
| M Arluison, F Javoy-Agid, C Feuerstein, M Tauc, M Conrath-Verrier, P Maill. Histofluorescence analysis of several systems of catecholaminergic nerve fibres within the rat neostriatum revealed by either restricted lesions of the substantia nigra or gamma-hydroxybutyrate. Brain research bulletin. vol 9. issue 1-6. 1983-02-25. PMID:7172034. |
in control animals and in the contralateral side of rats lesioned in the substantia nigra, the fluorescence of the dense plexus of dopamine nerve fibres appeared under the form of densely packed varicosities. |
1983-02-25 |
2023-08-12 |
rat |
| B E Jone. Relationship between catecholamine neurons and cerebral blood vessels studied by their simultaneous fluorescent revelation in the rat brainstem. Brain research bulletin. vol 9. issue 1-6. 1983-02-25. PMID:7172033. |
however, a special relationship of catecholamine cells to blood vessels was suggested, particularly in the case of dopamine neurons in the substantia nigra by the close apposition of cellular processes to adjacent small vessels. |
1983-02-25 |
2023-08-12 |
rat |
| A Lydén, B Larsson, N G Lindquis. Studies on the melanin affinity of haloperidol. Archives internationales de pharmacodynamie et de therapie. vol 259. issue 2. 1983-02-25. PMID:7181580. |
in vitro, haloperidol was found to be bound to beef-eye melanin and dopamine melanin (structurally similar to the melanin present in the pigmented nerve cells in the human substantia nigra). |
1983-02-25 |
2023-08-12 |
mouse |
| J Glowinski, Y Torrens, J C Beaujoua. The striatonigral substance P pathway and dopaminergic mechanisms. Ciba Foundation symposium. issue 91. 1983-01-19. PMID:6183075. |
finally, the effects of facilitation or prevention of sp transmission in the substantia nigra on the activity of nigrostriatal dopaminergic neurons have been studied in vivo in the cat by measuring dopamine released from nerve terminals and dendrites. |
1983-01-19 |
2023-08-12 |
mouse |
| K L Lovell, C A Bruner, K E Moor. Lack of effect of cerebellectomy on ascending dopaminergic neurons in the rat brain. Neuroscience letters. vol 32. issue 2. 1983-01-19. PMID:7145238. |
the dopamine content in striatum and substantia nigra of the rat was not altered 3 weeks after total or hemicerebellectomy. |
1983-01-19 |
2023-08-12 |
rat |
| F J Vaccarino, K B Frankli. Dopamine mediates ipsi- and contraversive circling elicited from the substantia nigra. Pharmacology, biochemistry, and behavior. vol 17. issue 3. 1983-01-07. PMID:6890683. |
dopamine mediates ipsi- and contraversive circling elicited from the substantia nigra. |
1983-01-07 |
2023-08-12 |
Not clear |
| J M Studler, F Javoy-Agid, F Cesselin, J C Legrand, Y Agi. CCK-8-Immunoreactivity distribution in human brain: selective decrease in the substantia nigra from parkinsonian patients. Brain research. vol 243. issue 1. 1982-12-02. PMID:6288173. |
in parkinson's disease, cck-8-i levels were only decreased in the substantia nigra where dopamine cell bodies lie, and not in striatal and corticolimbic dopamine projecting areas. |
1982-12-02 |
2023-08-12 |
human |
| H Baker, T H Joh, D J Rei. Time of appearance during development of differences in nigrostriatal tyrosine hydroxylase activity in two inbred mouse strains. Brain research. vol 256. issue 2. 1982-10-21. PMID:6125248. |
the greater activity of tyrosine hydroxylase (th) in substantia nigra and corpus striata of adult balb/cj than cba/j mice, is attributable to differences in the number of dopamine neurons in the ventral midbrain tegmentum. |
1982-10-21 |
2023-08-12 |
mouse |
| A Argiolas, M R Melis, F Fadda, G Serra, G L Gess. Effect of dopamine agonists and antagonists on DOPA formation in the substantia nigra. Journal of neurochemistry. vol 38. issue 1. 1982-10-12. PMID:6809898. |
effect of dopamine agonists and antagonists on dopa formation in the substantia nigra. |
1982-10-12 |
2023-08-12 |
Not clear |
| E Scarnati, C Pacitt. Neuronal responses to iontophoretically applied dopamine, glutamate, and GABA of identified dopaminergic cells in the rat substantia nigra after kainic acid-induced destruction of the striatum. Experimental brain research. vol 46. issue 3. 1982-09-24. PMID:6124446. |
neuronal responses to iontophoretically applied dopamine, glutamate, and gaba of identified dopaminergic cells in the rat substantia nigra after kainic acid-induced destruction of the striatum. |
1982-09-24 |
2023-08-12 |
rat |
| P Redgrave, I Mitchel. Photometric assessment of glyoxylic acid-induced fluorescence of dopamine in the caudate nucleus. Neuroscience. vol 7. issue 4. 1982-09-17. PMID:7099423. |
several experiments were performed to evaluate both the reliability and validity of these procedures as an index of the relative regional content of dopamine within the caudate: (1) the relative distribution of fluorescence intensity within the mouse striatum was in good agreement with previously reported distributions based on biochemical determination of regional dopamine levels within the rodent brain; (2) pharmacological manipulation of dopamine levels with gamma-butyrolactone and alpha-methyl-p-tyrosine combined with amphetamine produced predictable changes in the fluorescence intensity measurements of mouse caudate relative to untreated controls; (3) in rats pre-treated with alpha-methyl-p-tyrosine, unilateral electrical stimulation of the substantia nigra caused overall differences in fluorescence intensity between the caudate nucleus on each side of the brain, which were a function of both the duration of stimulation and the stimulating pulse frequency; (4) local injections of 6-hydroxydopamine unilaterally into the ventral tegmentum of animals pretreated with desmethylimipramine caused significant reductions in the intensity of fluorescence recorded from the ipsilateral striatum. |
1982-09-17 |
2023-08-12 |
mouse |