| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Taquet, F Javoy-Agid, F Cesselin, M Hamon, J C Legrand, Y Agi. Microtopography of methionine-enkephalin, dopamine and noradrenaline in the ventral mesencephalon of human control and Parkinsonian brains. Brain research. vol 235. issue 2. 1984-08-13. PMID:7188329. |
the topographical distributions of met-enkephalin, dopamine and noradrenaline were determined in serial frontal sections of human substantia nigra (pars compacta and pars reticulata) and ventral tegmental area. |
1984-08-13 |
2023-08-12 |
human |
| H Taquet, F Javoy-Agid, F Cesselin, M Hamon, J C Legrand, Y Agi. Microtopography of methionine-enkephalin, dopamine and noradrenaline in the ventral mesencephalon of human control and Parkinsonian brains. Brain research. vol 235. issue 2. 1984-08-13. PMID:7188329. |
noradrenaline levels in the substantia nigra and those of met-enkephalin, dopamine, and noradrenaline in the ventral tegmental area, exhibited only limited fluctuations from the anterior to the posterior part of each structure. |
1984-08-13 |
2023-08-12 |
human |
| H Taquet, F Javoy-Agid, F Cesselin, M Hamon, J C Legrand, Y Agi. Microtopography of methionine-enkephalin, dopamine and noradrenaline in the ventral mesencephalon of human control and Parkinsonian brains. Brain research. vol 235. issue 2. 1984-08-13. PMID:7188329. |
highly significant decreases in met-enkephalin, dopamine and noradrenaline levels were observed in the substantia nigra and ventral tegmental area of parkinsonian brains. |
1984-08-13 |
2023-08-12 |
human |
| H Taquet, F Javoy-Agid, F Cesselin, M Hamon, J C Legrand, Y Agi. Microtopography of methionine-enkephalin, dopamine and noradrenaline in the ventral mesencephalon of human control and Parkinsonian brains. Brain research. vol 235. issue 2. 1984-08-13. PMID:7188329. |
this observation, together with the close topographical association of dopamine and met-enkephalin in the substantia nigra, further supports the likely existence of important functional relationships between dopaminergic and enkephalinergic neurons in the human brain. |
1984-08-13 |
2023-08-12 |
human |
| B Bokobza, M Ruberg, B Scatton, F Javoy-Agid, Y Agi. [3H]spiperone binding, dopamine and HVA concentrations in Parkinson's disease and supranuclear palsy. European journal of pharmacology. vol 99. issue 2-3. 1984-08-07. PMID:6734727. |
the density of d2-type dopamine receptors, measured by the binding of [3h]spiperone was normal in the substantia nigra, caudate nucleus and nucleus accumbens of parkinsonian subjects and above control levels in the putamen, in spite of massive lesions of the dopaminergic neurons. |
1984-08-07 |
2023-08-12 |
human |
| B Bokobza, M Ruberg, B Scatton, F Javoy-Agid, Y Agi. [3H]spiperone binding, dopamine and HVA concentrations in Parkinson's disease and supranuclear palsy. European journal of pharmacology. vol 99. issue 2-3. 1984-08-07. PMID:6734727. |
dopamine levels were reduced in the putamen, caudate nucleus, and nucleus accumbens by 97, 85 and 68%, respectively and by 78 and 93% in the pars compacta and pars reticulata of the substantia nigra. |
1984-08-07 |
2023-08-12 |
human |
| R D Pinnoc. The actions of antipsychotic drugs on dopamine receptors in the rat substantia nigra. British journal of pharmacology. vol 81. issue 4. 1984-07-18. PMID:6144343. |
the actions of antipsychotic drugs on dopamine receptors in the rat substantia nigra. |
1984-07-18 |
2023-08-12 |
rat |
| R Owen, F Owen, M Poulter, T J Cro. Dopamine D2 receptors in substantia nigra in schizophrenia. Brain research. vol 299. issue 1. 1984-07-16. PMID:6144367. |
dopamine d2 receptors in substantia nigra in schizophrenia. |
1984-07-16 |
2023-08-12 |
Not clear |
| R Owen, F Owen, M Poulter, T J Cro. Dopamine D2 receptors in substantia nigra in schizophrenia. Brain research. vol 299. issue 1. 1984-07-16. PMID:6144367. |
dopamine d2 receptors were assessed in samples of substantia nigra from controls and schizophrenics. |
1984-07-16 |
2023-08-12 |
Not clear |
| R E Heikkila, A Hess, R C Duvoisi. Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice. Science (New York, N.Y.). vol 224. issue 4656. 1984-07-11. PMID:6610213. |
when mptp (30 milligrams per kilogram of body weight) was administered parenterally to mice, a decrease in concentrations of neostriatal dopamine and its metabolites, a decrease in the capacity of neostriatal synaptosomal preparations to accumulate [3h]dopamine, and a disappearance of nerve cells in the zona compacta of the substantia nigra were observed. |
1984-07-11 |
2023-08-12 |
mouse |
| J M Morihisa, R K Nakamura, W J Freed, M Mishkin, R J Wyat. Adrenal medulla grafts survive and exhibit catecholamine-specific fluorescence in the primate brain. Experimental neurology. vol 84. issue 3. 1984-07-10. PMID:6723885. |
parkinson's disease most consistently involves pathologic changes in the substantia nigra, which is the major source of dopamine to the striatum. |
1984-07-10 |
2023-08-12 |
rat |
| J M Morihisa, R K Nakamura, W J Freed, M Mishkin, R J Wyat. Adrenal medulla grafts survive and exhibit catecholamine-specific fluorescence in the primate brain. Experimental neurology. vol 84. issue 3. 1984-07-10. PMID:6723885. |
it has been shown that either fetal substantia nigra or adrenal medulla tissue implanted into the rat brain survives, produces dopamine, and improves behavioral abnormalities induced by deprivation of the caudate nucleus of its dopaminergic innervation. |
1984-07-10 |
2023-08-12 |
rat |
| B K Yamamoto, C R Free. Asymmetric dopamine and serotonin metabolism in nigrostriatal and limbic structures of the trained circling rat. Brain research. vol 297. issue 1. 1984-07-09. PMID:6202362. |
we have now studied changes in dopamine and serotonin turnover in nucleus accumbens, substantia nigra and amygdala. |
1984-07-09 |
2023-08-12 |
rat |
| B K Yamamoto, C R Free. Asymmetric dopamine and serotonin metabolism in nigrostriatal and limbic structures of the trained circling rat. Brain research. vol 297. issue 1. 1984-07-09. PMID:6202362. |
by contrast, dopamine turnover in substantia nigra exhibited a relative decline on the contralateral side. |
1984-07-09 |
2023-08-12 |
rat |
| R D Pinnoc. Sensitivity of compacta neurones in the rat substantia nigra slice to dopamine agonists. European journal of pharmacology. vol 96. issue 3-4. 1984-07-09. PMID:6676108. |
sensitivity of compacta neurones in the rat substantia nigra slice to dopamine agonists. |
1984-07-09 |
2023-08-12 |
rat |
| A Barbea. Manganese and extrapyramidal disorders (a critical review and tribute to Dr. George C. Cotzias). Neurotoxicology. vol 5. issue 1. 1984-06-20. PMID:6538948. |
thirdly the author proposes that the necessary event to the so-called "depigmentation" of the substantia nigra and subsequent bradykinetic "low dopamine" syndrome is an early enhanced turnover of dopamine. |
1984-06-20 |
2023-08-12 |
Not clear |
| A Barbea. Manganese and extrapyramidal disorders (a critical review and tribute to Dr. George C. Cotzias). Neurotoxicology. vol 5. issue 1. 1984-06-20. PMID:6538948. |
in turn, this increased synthesis of dopamine favours the production of large quantities of free radicals within the cell bodies in the substantia nigra, eventually overflowing the scavenging capacity of neuromelanin and their protective barrier, and causing cell death. |
1984-06-20 |
2023-08-12 |
Not clear |
| G Toffano, G E Savoini, F Moroni, G Lombardi, L Calzà, L F Agnat. Chronic GM1 ganglioside treatment reduces dopamine cell body degeneration in the substantia nigra after unilateral hemitransection in rat. Brain research. vol 296. issue 2. 1984-05-21. PMID:6142756. |
chronic gm1 ganglioside treatment reduces dopamine cell body degeneration in the substantia nigra after unilateral hemitransection in rat. |
1984-05-21 |
2023-08-12 |
rat |
| R D Myers, T F Le. In vivo release of dopamine during perfusion of neurotensin in substantia nigra of the unrestrained rat. Peptides. vol 4. issue 6. 1984-05-11. PMID:6672795. |
in vivo release of dopamine during perfusion of neurotensin in substantia nigra of the unrestrained rat. |
1984-05-11 |
2023-08-12 |
rat |
| R D Myers, T F Le. In vivo release of dopamine during perfusion of neurotensin in substantia nigra of the unrestrained rat. Peptides. vol 4. issue 6. 1984-05-11. PMID:6672795. |
the functional effect of neurotensin on the kinetics of dopamine (da) release in the substantia nigra of the freely moving rat was investigated. |
1984-05-11 |
2023-08-12 |
rat |