Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
T T Bondarenk. [Interaction of catecholamine and opiate structures of the brain at the neuronal level]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 69. issue 7. 1985-01-31. PMID:6096173. |
the results suggest that substantia nigra's opiate structures are able to modulate presynaptically the functions of the lateral hypothalamic neuronal dopamine receptors. |
1985-01-31 |
2023-08-12 |
rat |
J Glowinski, M J Besson, A Chéram. Role of the thalamus in the bilateral regulation of dopaminergic and GABAergic neurons in the basal ganglia. Ciba Foundation symposium. vol 107. 1985-01-24. PMID:6094123. |
the role of thalamic nuclei in the bilateral regulation of dopamine and gaba release in the caudate nucleus and substantia nigra is further demonstrated by studies showing that (1) electrical stimulation of thalamic motor nuclei induces bilateral asymmetrical changes in dopamine release resembling the changes evoked by unilateral sensory stimuli or stimulation of cerebellar nuclei; (2) electrical stimulation of intralaminar or some midline thalamic nuclei leads to bilateral (or contralateral) symmetrical changes in dopamine release, some of these effects being comparable to those induced by unilateral stimulation of the motor cortex; (3) unilateral lesions of motor or intralaminar thalamic nuclei reverse the changes in gaba release in the contralateral caudate nucleus or substantia nigra induced by unilateral infusion of muscimol into the nigra; and (4) unilateral infusion of gaba into thalamic motor nuclei induces bilateral symmetrical regulation of dopamine release in caudate nuclei by means of presynaptic facilitatory influences. |
1985-01-24 |
2023-08-12 |
Not clear |
J L Sadoul, F Chécler, P Kitabgi, W Rostène, F Javoy-Agid, J P Vincen. Loss of high affinity neurotensin receptors in substantia nigra from parkinsonian subjects. Biochemical and biophysical research communications. vol 125. issue 1. 1985-01-22. PMID:6095844. |
these results support the hypothesis of neurotensin receptors occurring on dopamine cell bodies and/or dendrites in human substantia nigra. |
1985-01-22 |
2023-08-12 |
human |
D Doudet, C Gross, B Bioula. [Activity of dopaminergic neurons of the substantia nigra: a functional significance?]. Comptes rendus des seances de la Societe de biologie et de ses filiales. vol 178. issue 3. 1985-01-03. PMID:6238655. |
in this study, neuronal activity of dopamine (da) containing neurons located in pars compacta of the substantia nigra is analysed by the use of the time interval histograms and autocorrelograms. |
1985-01-03 |
2023-08-12 |
Not clear |
A Dravid, A L Jaton, A Enz, P Fre. Spontaneous recovery from motor asymmetry in adult rats with 6-hydroxydopamine-induced partial lesions of the substantia nigra. Brain research. vol 311. issue 2. 1984-12-28. PMID:6149789. |
animals with 6-hydroxydopamine-induced partial unilateral lesions of the substantia nigra exhibit spontaneous recovery from motor asymmetry, a transitory increase in dopamine turnover and an increase in tyrosine hydroxylase activity in the denervated striatum. |
1984-12-28 |
2023-08-12 |
rat |
P Aebischer, W Schult. The activity of pars compacta neurons of the monkey substantia nigra is depressed by apomorphine. Neuroscience letters. vol 50. issue 1-3. 1984-12-20. PMID:6493628. |
in the substantia nigra of anesthetized and awake monkeys, presumptive dopamine cells of the pars compacta were electrophysiologically discriminated against non-dopaminergic cells of the pars reticulata by their lower discharge rate (0.5-8 vs 20-130 imp./s), their longer impulse duration (means 2.05 vs 0.92 ms), and their exclusive depression following systemic injection of the dopamine agonist apomorphine (24 out of 30 compacta neurons at 0.05-0.1 mg/kg s.c.). |
1984-12-20 |
2023-08-12 |
monkey |
T Kato, K Ishii, M Iked. Voltammetry in unanesthetized rat: increases of striatal dopamine turnover after unilateral haloperidol injection into the substantia nigra. Neuroscience letters. vol 50. issue 1-3. 1984-12-20. PMID:6493630. |
voltammetry in unanesthetized rat: increases of striatal dopamine turnover after unilateral haloperidol injection into the substantia nigra. |
1984-12-20 |
2023-08-12 |
rat |
T Kato, K Ishii, M Iked. Voltammetry in unanesthetized rat: increases of striatal dopamine turnover after unilateral haloperidol injection into the substantia nigra. Neuroscience letters. vol 50. issue 1-3. 1984-12-20. PMID:6493630. |
these data support the idea that unilateral injection of haloperidol into the substantia nigra in freely moving rats increases dopamine turnover in the bilateral striata. |
1984-12-20 |
2023-08-12 |
rat |
V Leviel, C Kerny, C Barberis, B Guibert, F Daude. Blockade by frontocortical lesion of reciprocal regulation between the two nigrostriatal dopaminergic pathways. Neuroscience. vol 13. issue 1. 1984-12-18. PMID:6092996. |
tritiated dopamine synthesized from tritiated tyrosine was estimated simultaneously in the two caudate nuclei and the two substantia nigra of cats anaesthesized with halothane. |
1984-12-18 |
2023-08-12 |
Not clear |
V Leviel, C Kerny, C Barberis, B Guibert, F Daude. Blockade by frontocortical lesion of reciprocal regulation between the two nigrostriatal dopaminergic pathways. Neuroscience. vol 13. issue 1. 1984-12-18. PMID:6092996. |
in control animals, the electrical stimulation of the right forelimb enhanced dopamine release in the right caudate nucleus and decreased dopamine release in the right substantia nigra. |
1984-12-18 |
2023-08-12 |
Not clear |
V Leviel, C Kerny, C Barberis, B Guibert, F Daude. Blockade by frontocortical lesion of reciprocal regulation between the two nigrostriatal dopaminergic pathways. Neuroscience. vol 13. issue 1. 1984-12-18. PMID:6092996. |
however in cats with extensive lesions of the left pericruciate cortex, an increase in the release of dopamine in the left substantia nigra was the only detectable effect of these two treatments. |
1984-12-18 |
2023-08-12 |
Not clear |
V Leviel, C Kerny, C Barberis, B Guibert, F Daude. Blockade by frontocortical lesion of reciprocal regulation between the two nigrostriatal dopaminergic pathways. Neuroscience. vol 13. issue 1. 1984-12-18. PMID:6092996. |
these results suggest that the cortical structures are involved not only in the transfer of information between the two dopaminergic pathways but are also involved with regulation of the release of dopamine in the striatum originating in the substantia nigra. |
1984-12-18 |
2023-08-12 |
Not clear |
A Lydén, B S Larsson, N G Lindquis. Melanin affinity of manganese. Acta pharmacologica et toxicologica. vol 55. issue 2. 1984-12-05. PMID:6437141. |
the melanin affinity of manganese was studied in vitro using melanin isolated from beef eyes or human hair, and synthetic dopamine melanin, which is known to be structurally similar to the melanin present in the pigmented nerve cells in the human substantia nigra. |
1984-12-05 |
2023-08-12 |
mouse |
T H Moran, K L Kubos, P R Sanberg, R G Robinso. Marked behavioral and biochemical sensitivity to lesion size in the posterior cortex of the rat. Life sciences. vol 35. issue 13. 1984-11-19. PMID:6482655. |
this increased activity was accompanied by significant elevations in substantia nigra and caudate nucleus dopamine concentrations. |
1984-11-19 |
2023-08-12 |
rat |
E H Lee, M A Geye. Dopamine autoreceptor mediation of the effects of apomorphine on serotonin neurons. Pharmacology, biochemistry, and behavior. vol 21. issue 2. 1984-11-15. PMID:6207549. |
together with previous findings that the serotonergic actions of systemic apo were antagonized by haloperidol or intraventricular 6-hydroxydopamine pretreatment; and the selective dopamine (da) autoreceptor agonist 3-3-hydroxyphenyl-n-n-propyl-piperidine mimicked the effects of apo on 5-ht neurons, these results suggest that the observed effects of apo on the mesostriatal serotonergic system are probably mediated through da autoreceptors in the substantia nigra and possibly by a direct nigroraphe pathway. |
1984-11-15 |
2023-08-12 |
rat |
R Romo, A Chéramy, G Godeheu, J Glowinsk. Distinct commissural pathways are involved in the enhanced release of dopamine induced in the contralateral caudate nucleus and substantia nigra by unilateral application of GABA in the cat thalamic motor nuclei. Brain research. vol 308. issue 1. 1984-11-14. PMID:6383515. |
distinct commissural pathways are involved in the enhanced release of dopamine induced in the contralateral caudate nucleus and substantia nigra by unilateral application of gaba in the cat thalamic motor nuclei. |
1984-11-14 |
2023-08-12 |
cat |
R Romo, A Chéramy, G Godeheu, J Glowinsk. Distinct commissural pathways are involved in the enhanced release of dopamine induced in the contralateral caudate nucleus and substantia nigra by unilateral application of GABA in the cat thalamic motor nuclei. Brain research. vol 308. issue 1. 1984-11-14. PMID:6383515. |
the effects of diencephalic or telencephalic commissural sectioning on the changes in [3h]dopamine ([3h]da) release from nerve terminals (in the caudate nucleus, cn) and dendrites (in the substantia nigra, sn) of the two nigro-striatal dopaminergic pathways induced by the application of gaba (10(-5) m, 30 min) into the left ventralis medialis (vm) or ventralis lateralis (vl) thalamic nuclei were investigated. |
1984-11-14 |
2023-08-12 |
cat |
T D Reisine, P Soubrié, A Ferron, C Blas, R Romo, J Glowinsk. Evidence for a dopaminergic innervation of the cat lateral habenula: its role in controlling serotonin transmission in the basal ganglia. Brain research. vol 308. issue 2. 1984-11-14. PMID:6478209. |
furthermore, in anesthetized animals with a push-pull cannula implanted in each caudate nucleus and substantia nigra habenular applications of dopamine (10(-7) m) reduced nigral but not striatal release of [3h]serotonin continuously formed from [3h]tryptophan. |
1984-11-14 |
2023-08-12 |
cat |
T H McNeill, L L Koek, J W Haycoc. The nigrostriatal system and aging. Peptides. vol 5 Suppl 1. 1984-11-09. PMID:6148736. |
this report compared the morphology of nigrostriatal dopamine (da) neurons of the substantia nigra and ventral tegmental area of the c57b1/6n nia mouse with the morphology of da neurons of the nigrostriatal pathway in aged human brain and in one case diagnosed to have senile dementia of the alzheimer's type (sdat). |
1984-11-09 |
2023-08-12 |
mouse |
T L Perry, V W Yong, M Ito, J G Foulks, R A Wall, D V Godin, R M Clavie. Nigrostriatal dopaminergic neurons remain undamaged in rats given high doses of L-DOPA and carbidopa chronically. Journal of neurochemistry. vol 43. issue 4. 1984-10-25. PMID:6147392. |
when sacrificed 60 days after l-dopa treatment ended, all rats had normal tyrosine hydroxylase activities and dopamine contents in their striata, and cell counts were normal in the substantia nigra. |
1984-10-25 |
2023-08-12 |
rat |