| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J K Ritter, C J Schmidt, J W Gibb, G R Hanso. Dopamine-mediated increases in nigral substance P-like immunoreactivity. Biochemical pharmacology. vol 34. issue 17. 1985-10-03. PMID:2412564. |
thus, treatment of rats with the specific dopamine (da) uptake blockers amfonelic acid (afa) and nomifensine caused elevations in the spli levels within the substantia nigra similar to that of methamphetamine (meth). |
1985-10-03 |
2023-08-11 |
rat |
| P Onali, G Mereu, M C Olianas, B Bunse, Z Rossetti, G L Gess. SCH 23390, a selective D1 dopamine receptor blocker, enhances the firing rate of nigral dopaminergic neurons but fails to activate striatal tyrosine hydroxylase. Brain research. vol 340. issue 1. 1985-10-03. PMID:2862956. |
the intraperitoneal administration of sch 23390, a selective d1 receptor antagonist, produced catalepsy and increased the firing rate of dopamine (da) neurons in the substantia nigra (sn-da neurons). |
1985-10-03 |
2023-08-11 |
Not clear |
| R D Pinnoc. Neurotensin depolarizes substantia nigra dopamine neurones. Brain research. vol 338. issue 1. 1985-10-03. PMID:4027584. |
neurotensin depolarizes substantia nigra dopamine neurones. |
1985-10-03 |
2023-08-11 |
Not clear |
| N E Andén, M Grabowska-Andén, S Lindgren, M Owelin. Very rapid turnover of dopamine in noradrenaline cell body regions. Naunyn-Schmiedeberg's archives of pharmacology. vol 329. issue 3. 1985-09-19. PMID:4022136. |
the contents of dopamine, noradrenaline and their deaminated metabolites, 3,4-dihydroxyphenylacetic acid (dopac) and 3,4-dihydroxyphenylethylene glycol (dopeg) were determined in rats in two noradrenaline cell body regions, i.e., the superior cervical ganglion and the locus coeruleus, and in one dopamine cell body region, the substantia nigra. |
1985-09-19 |
2023-08-11 |
rat |
| N E Andén, M Grabowska-Andén, S Lindgren, M Owelin. Very rapid turnover of dopamine in noradrenaline cell body regions. Naunyn-Schmiedeberg's archives of pharmacology. vol 329. issue 3. 1985-09-19. PMID:4022136. |
the dopamine-beta-hydroxylase inhibitor fla-63 swiftly elevated the content of dopamine and it lowered the content of noradrenaline in the two noradrenaline regions, but it was ineffective in the substantia nigra. |
1985-09-19 |
2023-08-11 |
rat |
| G Mereu, M Collu, E Ongini, G Biggio, G L Gess. SCH 23390, a selective dopamine D1 antagonist, activates dopamine neurons but fails to prevent their inhibition by apomorphine. European journal of pharmacology. vol 111. issue 3. 1985-09-16. PMID:3894035. |
sch 23390, a rather selective d1 receptor blocker, activates the firing rate of dopamine (da) neurons in the substantia nigra (sn-da neurons) in rats, similarly to haloperidol (a d1-d2 receptor antagonist) and sulpiride (a selective d2 receptor blocker). |
1985-09-16 |
2023-08-11 |
rat |
| L R Skirboll, D W Homme. Electrophysiological studies of the role of cholecystokinin in the substantia nigra and its interactions with dopamine. Annals of the New York Academy of Sciences. vol 448. 1985-09-06. PMID:3861121. |
electrophysiological studies of the role of cholecystokinin in the substantia nigra and its interactions with dopamine. |
1985-09-06 |
2023-08-11 |
Not clear |
| E Kelly, P Jenner, C D Marsde. The effects of dopamine and dopamine agonists on the release of 3H-GABA and 3H-5HT from rat nigral slices. Biochemical pharmacology. vol 34. issue 15. 1985-08-16. PMID:3925957. |
these results suggest that only high concentration of some dopamine agonists can modulate 3h-5ht and 3h-gaba release in substantia nigra. |
1985-08-16 |
2023-08-11 |
rat |
| E Kelly, P Jenner, C D Marsde. The effects of dopamine and dopamine agonists on the release of 3H-GABA and 3H-5HT from rat nigral slices. Biochemical pharmacology. vol 34. issue 15. 1985-08-16. PMID:3925957. |
however, dopamine either had no effect, or its actions were not reversed by dopamine receptor blockade, so it appears unlikely that dendritic dopamine release will influence gaba and 5ht release in substantia nigra. |
1985-08-16 |
2023-08-11 |
rat |
| E Kelly, P Jenner, C D Marsde. Lack of effect of intranigral administration of a dopamine analogue, (+/-)-3-(3-hydroxyphenyl)-N,n-propylpiperidine [(+/-)-3-PPP], on nigrostriatal dopamine neurones. Neuroscience letters. vol 56. issue 1. 1985-08-12. PMID:4011049. |
bilateral injection of apomorphine into the zona reticulata of substantia nigra in rats reduced locomotor activity and striatal dopamine (da) turnover. |
1985-08-12 |
2023-08-11 |
rat |
| I Divac, W Lichtensteiger, A Gad. Catecholamine microfluorometry of nigral perikarya and tyrosine hydroxylase assay in some telencephalic structures of rats exposed to different behavioral situations. Acta neurobiologiae experimentalis. vol 44. issue 6. 1985-08-09. PMID:6152597. |
in a similar experimental paradigm, we measured presently activity of tyrosine hydroxylase in several telencephalic formations and intensity of dopamine fluorescence in neurons of the substantia nigra. |
1985-08-09 |
2023-08-12 |
rat |
| D W Hommer, M Palkovits, J N Crawley, S M Paul, L R Skirbol. Cholecystokinin-induced excitation in the substantia nigra: evidence for peripheral and central components. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 5. issue 6. 1985-07-30. PMID:4009236. |
cholecystokinin (cck), one of the most common brain peptides, coexists with dopamine (da) in neurons of the medial substantia nigra (sn). |
1985-07-30 |
2023-08-11 |
Not clear |
| S H Cha. Physiologic and pharmacologic characterization of a novel group of substantia nigra zona reticulata neurons involved in striatal dopamine regulation. Annals of the Academy of Medicine, Singapore. vol 14. issue 1. 1985-07-25. PMID:2860839. |
physiologic and pharmacologic characterization of a novel group of substantia nigra zona reticulata neurons involved in striatal dopamine regulation. |
1985-07-25 |
2023-08-11 |
rat |
| K G Lloyd, M T Willigens, M Goldstei. Induction and reversal of dopamine dyskinesia in rat, cat, and monkey. Psychopharmacology. Supplementum. vol 2. 1985-07-24. PMID:2987905. |
as these latter doses of progabide also antagonize apomorphine-induced circling in rats with a unilateral lesion of the substantia nigra, it is likely that this action is exerted at or beyond the dopamine target cell. |
1985-07-24 |
2023-08-11 |
rat |
| J S Hong, K Yoshikawa, T Kanamatsu, S L Sabo. Modulation of striatal enkephalinergic neurons by antipsychotic drugs. Federation proceedings. vol 44. issue 9. 1985-07-17. PMID:3838946. |
several lines of evidence, which showed that striatal levels of [met5]enkephalin (me) increase after the nigrostriatal dopaminergic pathway was interrupted by hemitransection or direct administration of 6-hydroxydopamine to the substantia nigra, or after repeated injections of either reserpine or haloperidol, suggest that dopamine (da) plays an important role in regulating the metabolism of me-containing neurons in the striatum. |
1985-07-17 |
2023-08-11 |
rat |
| E Kelly, P Jenner, C D Marsde. Evidence that [3H]dopamine is taken up and released from nondopaminergic nerve terminals in the rat substantia nigra in vitro. Journal of neurochemistry. vol 45. issue 1. 1985-07-17. PMID:3923157. |
evidence that [3h]dopamine is taken up and released from nondopaminergic nerve terminals in the rat substantia nigra in vitro. |
1985-07-17 |
2023-08-11 |
rat |
| E Kelly, P Jenner, C D Marsde. Evidence that [3H]dopamine is taken up and released from nondopaminergic nerve terminals in the rat substantia nigra in vitro. Journal of neurochemistry. vol 45. issue 1. 1985-07-17. PMID:3923157. |
potassium chloride (25 mm) and (+)-amphetamine (100 microm) both stimulated the release of radioactivity from slices of substantia nigra preincubated with [3h]3,4-dihydroxyphenylethylamine [( 3h]dopamine). |
1985-07-17 |
2023-08-11 |
rat |
| R D O'Neill, M Fillen. Detection of homovanillic acid in vivo using microcomputer-controlled voltammetry: simultaneous monitoring of rat motor activity and striatal dopamine release. Neuroscience. vol 14. issue 3. 1985-06-14. PMID:3921870. |
the effect on peak 3 of either unilateral 6-hydroxydopamine lesion of the substantia nigra or intraperitoneal administration of alpha-methyl-paratyrosine, supports our earlier conclusion that peak 3 is due to the dopamine metabolite homovanillic acid. |
1985-06-14 |
2023-08-11 |
rat |
| G Mereu, G L Gess. Ethanol excites dopamine (DA) neurons and inhibits non-dopamine (non-DA) neurons in the Substantia nigra of rats. Annali dell'Istituto superiore di sanita. vol 20. issue 1. 1985-06-06. PMID:6099989. |
ethanol excites dopamine (da) neurons and inhibits non-dopamine (non-da) neurons in the substantia nigra of rats. |
1985-06-06 |
2023-08-12 |
rat |
| U K Rinne, J O Rinne, J K Rinne, K Laakso, P Lönnber. Brain neurotransmitters and neuropeptides in Parkinson's disease. Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia. vol 34. issue 3. 1985-05-23. PMID:6099688. |
however, changes in dopamine neurons were found also outside the extrapyramidal system, showing that there is a more general brain defect than just the loss of substantia nigra dopamine neurons. |
1985-05-23 |
2023-08-12 |
Not clear |