| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Ishii, T Kat. Increase of dopamine turnover in bilateral striata after unilateral injection of haloperidol into substantia nigra of unrestrained rats. Brain research. vol 359. issue 1-2. 1986-01-24. PMID:3000522. |
increase of dopamine turnover in bilateral striata after unilateral injection of haloperidol into substantia nigra of unrestrained rats. |
1986-01-24 |
2023-08-11 |
rat |
| A N van den Pol, A D Smith, J F Powel. GABA axons in synaptic contact with dopamine neurons in the substantia nigra: double immunocytochemistry with biotin-peroxidase and protein A-colloidal gold. Brain research. vol 348. issue 1. 1986-01-22. PMID:2866017. |
gaba axons in synaptic contact with dopamine neurons in the substantia nigra: double immunocytochemistry with biotin-peroxidase and protein a-colloidal gold. |
1986-01-22 |
2023-08-11 |
rat |
| D L Toan, W Schult. Responses of rat pallidum cells to cortex stimulation and effects of altered dopaminergic activity. Neuroscience. vol 15. issue 3. 1986-01-22. PMID:2866467. |
the dopaminergic influences on this corticopallidal impulse transmission were assessed by the systemic administration of the dopamine receptor-blocking neuroleptics, haloperidol and fluphenazine, as well as by conditioning electrical stimulation of the substantia nigra. |
1986-01-22 |
2023-08-11 |
rat |
| M S Star. Multiple opiate receptors may be involved in suppressing gamma-aminobutyrate release in substantia nigra. Life sciences. vol 37. issue 24. 1986-01-17. PMID:2999545. |
slices of rat substantia nigra were preloaded with tritiated gamma-aminobutyrate (gaba) or dopamine (da) and perfused with krebs solution containing 5 microm aminooxyacetic acid or 10 microm nialamide to inhibit the catabolism of gaba and da respectively. |
1986-01-17 |
2023-08-11 |
rat |
| E Rosengren, E Linder-Eliasson, A Carlsso. Detection of 5-S-cysteinyldopamine in human brain. Journal of neural transmission. vol 63. issue 3-4. 1986-01-10. PMID:3840838. |
the compound could be detected in brain regions rich in dopamine (caudate nucleus, putamen, globus pallidus and substantia nigra) but not in other regions (cerebellum, occipital cortex). |
1986-01-10 |
2023-08-11 |
human |
| T L Perry, V W Yong, R M Clavier, K Jones, J M Wright, J G Foulks, R A Wal. Partial protection from the dopaminergic neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by four different antioxidants in the mouse. Neuroscience letters. vol 60. issue 2. 1985-12-18. PMID:3877260. |
c57 black mice given a single injection of n-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp), 40 mg/kg, developed marked reduction of striatal dopamine content and loss of dopaminergic neurons in the zona compacta of the substantia nigra. |
1985-12-18 |
2023-08-11 |
mouse |
| T L Perry, V W Yong, R M Clavier, K Jones, J M Wright, J G Foulks, R A Wal. Partial protection from the dopaminergic neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by four different antioxidants in the mouse. Neuroscience letters. vol 60. issue 2. 1985-12-18. PMID:3877260. |
however, pretreatment with any one of four different antioxidants, alpha-tocopherol, beta-carotene, ascorbic acid or n-acetylcysteine, significantly decreased mptp-induced striatal dopamine loss, and alpha-tocopherol prevented neuronal loss in the substantia nigra. |
1985-12-18 |
2023-08-11 |
mouse |
| A Lydén, U Bondesson, B S Larsson, N G Lindquist, L I Olsso. Autoradiography of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): uptake in the monoaminergic pathways and in melanin containing tissues. Acta pharmacologica et toxicologica. vol 57. issue 2. 1985-12-13. PMID:3877403. |
mptp has earlier been found to have high affinity in vitro for dopamine melanin, which is similar to the pigment in substantia nigra. |
1985-12-13 |
2023-08-11 |
mouse |
| Y Ohno, M Sasa, S Takaor. Dopamine D-2 receptor-mediated excitation of caudate nucleus neurons from the substantia nigra. Life sciences. vol 37. issue 16. 1985-11-21. PMID:3900614. |
dopamine d-2 receptor-mediated excitation of caudate nucleus neurons from the substantia nigra. |
1985-11-21 |
2023-08-11 |
Not clear |
| Y Ohno, M Sasa, S Takaor. Dopamine D-2 receptor-mediated excitation of caudate nucleus neurons from the substantia nigra. Life sciences. vol 37. issue 16. 1985-11-21. PMID:3900614. |
microiontophoretic studies using cats anesthetized with alpha-chloralose were performed to elucidate whether the excitatory response of caudate nucleus (cn) neurons upon stimulation of the pars compacta of the substantia nigra (sn) is mediated by the dopamine d-1 or d-2 receptor. |
1985-11-21 |
2023-08-11 |
Not clear |
| T M Ivanova, R Kvetnanskiĭ, T I Belova, Z Oprshalova, M Dobrakovov. [Catecholamines in nuclei of the brains of the August strain rat during immobilization stress]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 71. issue 7. 1985-11-07. PMID:4043426. |
sharp increase of the bp in the august rats was related to obvious decrease of epinephrine content in a1, norepinephrine in locus coeruleus and dopamine in substantia nigra. |
1985-11-07 |
2023-08-11 |
rat |
| T L Perry, V W Yong, K Jones, R A Wall, R M Clavier, J G Foulks, J M Wrigh. Effects of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its metabolite, N-methyl-4-phenylpyridinium ion, on dopaminergic nigrostriatal neurons in the mouse. Neuroscience letters. vol 58. issue 3. 1985-11-06. PMID:3876525. |
a single subcutaneous injection in the c57 black mouse of 40 mg/kg of n-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) causes a 90% depletion of striatal dopamine, as well as loss of 33% of neuronal cell bodies in the substantia nigra, zona compacta. |
1985-11-06 |
2023-08-11 |
mouse |
| M E Trulso. Simultaneous recording of substantia nigra neurons and voltammetric release of dopamine in the caudate of behaving cats. Brain research bulletin. vol 15. issue 2. 1985-11-06. PMID:4041929. |
simultaneous recording of substantia nigra neurons and voltammetric release of dopamine in the caudate of behaving cats. |
1985-11-06 |
2023-08-11 |
cat |
| M E Trulso. Simultaneous recording of substantia nigra neurons and voltammetric release of dopamine in the caudate of behaving cats. Brain research bulletin. vol 15. issue 2. 1985-11-06. PMID:4041929. |
simultaneous electrophysiological recordings of single dopamine-containing neurons in the pars compacta of the substantia nigra and the voltammetric release of dopamine in the caudate were made in the behaving cat. |
1985-11-06 |
2023-08-11 |
cat |
| S J Kish, C Morito, O Hornykiewic. Glutathione peroxidase activity in Parkinson's disease brain. Neuroscience letters. vol 58. issue 3. 1985-11-06. PMID:4047494. |
although the magnitude of the glutathione peroxidase deficiency in parkinson's disease substantia nigra was small (19% reduction), coupled with the reported marked deficiency of reduced glutathione [9] it may represent one of the contributing factors leading to nigral dopamine neurone loss. |
1985-11-06 |
2023-08-11 |
Not clear |
| G Rose, G Gerhardt, I Strömberg, L Olson, B Hoffe. Monoamine release from dopamine-depleted rat caudate nucleus reinnervated by substantia nigra transplants: an in vivo electrochemical study. Brain research. vol 341. issue 1. 1985-11-05. PMID:4041791. |
previous studies have shown that fetal substantia nigra (sn) transplanted into a cavity overlying a dopamine (da)-denervated caudate nucleus can reverse a number of the behavioral abnormalities induced by the denervation. |
1985-11-05 |
2023-08-11 |
rat |
| J M Durand-Gorde, J Bert, A Nieoullo. Changes in tyrosine hydroxylase, glutamic acid decarboxylase and choline acetyltransferase after local microinoculation of scrapie agent into the nigrostriatal system of the golden hamster. Brain research. vol 341. issue 2. 1985-11-04. PMID:2864098. |
the microinoculation of a homogenate of an infected brain unilaterally into the substantia nigra (sn) provokes a decrease in tyrosine hydroxylase (th), the synthesizing enzyme for dopamine in the dopaminergic neurones, in the striatum ipsilateral to the injected sn. |
1985-11-04 |
2023-08-11 |
Not clear |
| M E Trulson, K Araste. Morphine increases the activity of midbrain dopamine neurons in vitro. European journal of pharmacology. vol 114. issue 1. 1985-10-29. PMID:2931290. |
morphine was more potent on ventral tegmental area than substantia nigra dopamine neurons. |
1985-10-29 |
2023-08-11 |
mouse |
| M E Trulson, K Araste. Morphine increases the activity of midbrain dopamine neurons in vitro. European journal of pharmacology. vol 114. issue 1. 1985-10-29. PMID:2931290. |
these data suggest that midbrain dopamine neurons contain receptors for opiates, and that ventral tegmental area neurons are more sensitive to the action of opiates than substantia nigra neurons. |
1985-10-29 |
2023-08-11 |
mouse |
| L A Chiodo, B S Bunne. Possible mechanisms by which repeated clozapine administration differentially affects the activity of two subpopulations of midbrain dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 5. issue 9. 1985-10-17. PMID:2863337. |
extracellular single-cell recording techniques were employed to study the mechanism of action of repeated oral clozapine administration on the in vivo spontaneous activity of substantia nigra (a9) and ventral tegmental area (a10) dopamine (da)-containing neurons in the rat. |
1985-10-17 |
2023-08-11 |
rat |