| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Vives, G J Mogenso. Electrophysiological study of the effects of D1 and D2 dopamine antagonists on the interaction of converging inputs from the sensory-motor cortex and substantia nigra neurons in the rat. Neuroscience. vol 17. issue 2. 1986-05-30. PMID:3517688. |
electrophysiological study of the effects of d1 and d2 dopamine antagonists on the interaction of converging inputs from the sensory-motor cortex and substantia nigra neurons in the rat. |
1986-05-30 |
2023-08-11 |
rat |
| O Magnusson, C J Fowler, C Köhler, S O Ogre. Dopamine D2 receptors and dopamine metabolism. Relationship between biochemical and behavioural effects of substituted benzamide drugs. Neuropharmacology. vol 25. issue 2. 1986-05-23. PMID:2939362. |
remoxipride and haloperidol had little or no effect on the turnover of dopamine in either the hypothalamus or substantia nigra at the ed50 doses of these compounds for antagonism of apomorphine-induced stereotypy. |
1986-05-23 |
2023-08-11 |
rat |
| T C Napier, D A Gay, K L Hulebak, G R Brees. Behavioral and biochemical assessment of time-related changes in globus pallidus and striatal dopamine induced by intranigrally administered neurotensin. Peptides. vol 6. issue 6. 1986-05-23. PMID:3938838. |
microinjection of neurotensin (nt; 2 and 5 micrograms) into the substantia nigra zona compacta caused an increase in dopamine (da) and da metabolites in the rodent globus pallidus and striatum which persisted for at least 20 hours after peptide administration. |
1986-05-23 |
2023-08-11 |
rat |
| T C Napier, D A Gay, K L Hulebak, G R Brees. Behavioral and biochemical assessment of time-related changes in globus pallidus and striatal dopamine induced by intranigrally administered neurotensin. Peptides. vol 6. issue 6. 1986-05-23. PMID:3938838. |
these studies indicated that: dopaminergic functions of the globus pallidus are influenced, like the striatum, by manipulations of the substantia nigra: nt and ghb likely act via different mechanisms to effect nigral dopamine-containing cells; and nt was capable of inducing changes in dopamine neurons which had long term consequences. |
1986-05-23 |
2023-08-11 |
rat |
| M van den Buuse, D H Versteeg, W de Jon. Brain dopamine depletion by lesions in the substantia nigra attenuates the development of hypertension in the spontaneously hypertensive rat. Brain research. vol 368. issue 1. 1986-05-22. PMID:3006867. |
brain dopamine depletion by lesions in the substantia nigra attenuates the development of hypertension in the spontaneously hypertensive rat. |
1986-05-22 |
2023-08-11 |
rat |
| M van den Buuse, D H Versteeg, W de Jon. Brain dopamine depletion by lesions in the substantia nigra attenuates the development of hypertension in the spontaneously hypertensive rat. Brain research. vol 368. issue 1. 1986-05-22. PMID:3006867. |
after substantia nigra lesions depletion of dopamine was found especially in the nucleus caudatus posterior and the dorsomedial nucleus. |
1986-05-22 |
2023-08-11 |
rat |
| M C McNamara, J L Gingras-Leatherman, E E Lawso. Effect of hypoxia on brainstem concentration of biogenic amines in postnatal rabbits. Brain research. vol 390. issue 2. 1986-04-28. PMID:3955374. |
radioenzymatic assays were used to determine the concentration of dopamine, norepinephrine and serotonin in the following brainstem nuclei: substantia nigra, locus coeruleus, dorsal raphe and the nucleus reticularis pontis oralis. |
1986-04-28 |
2023-08-11 |
rabbit |
| J A Joseph, G S Roth, A S Lipp. Reduction of motor behavioral deficits in senescent animals via chronic prolactin administration. I. Rotational behavior. Neurobiology of aging. vol 7. issue 1. 1986-04-22. PMID:3081822. |
the effects of chronic prolactin administration on amphetamine or dopamine (da) induced rotational behavior was examined in mature (6 month) and senescent (24 month) wistar rats which were unilaterally lesioned in the left substantia nigra with 6-hydroxydopamine. |
1986-04-22 |
2023-08-11 |
rat |
| T C Napier, B S Givens, D W Schulz, B S Bunney, G R Breese, R B Mailma. SCH23390 effects on apomorphine-induced responses of nigral dopaminergic neurons. The Journal of pharmacology and experimental therapeutics. vol 236. issue 3. 1986-04-18. PMID:3512819. |
collectively, these results agree with previous studies which suggest that dopamine receptors located on dopamine-containing neurons of the substantia nigra zona compacta are likely not of the d1-type. |
1986-04-18 |
2023-08-11 |
Not clear |
| R T Matthews, D C Germa. Evidence for a functional role of dopamine type-1 (D-1) receptors in the substantia nigra of rats. European journal of pharmacology. vol 120. issue 1. 1986-04-10. PMID:2868905. |
evidence for a functional role of dopamine type-1 (d-1) receptors in the substantia nigra of rats. |
1986-04-10 |
2023-08-11 |
rat |
| R T Matthews, D C Germa. Evidence for a functional role of dopamine type-1 (D-1) receptors in the substantia nigra of rats. European journal of pharmacology. vol 120. issue 1. 1986-04-10. PMID:2868905. |
the microiontophoretic application of dopamine onto neurons in the substantia nigra of rats increased the spontaneous activity of zona reticulata (zr) neurons but decreased the activity of zone compacta (zc) neurons. |
1986-04-10 |
2023-08-11 |
rat |
| A J Bradbury, B Costall, M E Kelly, R J Naylor, J A Smit. Biochemical correlates of motor changes caused by the manipulation of dopamine function in the substantia nigra of the mouse. Neuropharmacology. vol 24. issue 12. 1986-04-07. PMID:4094652. |
biochemical correlates of motor changes caused by the manipulation of dopamine function in the substantia nigra of the mouse. |
1986-04-07 |
2023-08-11 |
mouse |
| A J Bradbury, B Costall, M E Kelly, R J Naylor, J A Smit. Biochemical correlates of motor changes caused by the manipulation of dopamine function in the substantia nigra of the mouse. Neuropharmacology. vol 24. issue 12. 1986-04-07. PMID:4094652. |
2-di-n-propylamino-5,6-dihydroxytetralin, injected bilaterally into the substantia nigra of the mouse, caused dose-dependent motor inhibition which was associated with decreased levels of dopac and increased levels of dopamine in the striatum. |
1986-04-07 |
2023-08-11 |
mouse |
| A J Bradbury, B Costall, M E Kelly, R J Naylor, J A Smit. Biochemical correlates of motor changes caused by the manipulation of dopamine function in the substantia nigra of the mouse. Neuropharmacology. vol 24. issue 12. 1986-04-07. PMID:4094652. |
(-)sulpiride, injected into the substantia nigra, antagonised the locomotor depression although the partial antagonism of the elevation in the level of dopamine in the striatum and of the reduction in levels of dopac did not achieve significance. |
1986-04-07 |
2023-08-11 |
mouse |
| A J Bradbury, B Costall, M E Kelly, R J Naylor, J A Smit. Biochemical correlates of motor changes caused by the manipulation of dopamine function in the substantia nigra of the mouse. Neuropharmacology. vol 24. issue 12. 1986-04-07. PMID:4094652. |
the injection of tetralin into the substantia nigra also caused biochemical changes in limbic areas (nucleus accumbens and tuberculum olfactorium), where the levels of dopamine and dopac were elevated, and in the frontal cortex where the levels of dopac were reduced. |
1986-04-07 |
2023-08-11 |
mouse |
| I C Kilpatrick, M S Starr, M Summerhaye. Brain dopamine activity following intranigral or intrathalamic drug injections in the rat. Brain research bulletin. vol 15. issue 6. 1986-03-21. PMID:3910169. |
stereotaxic injection of muscimol into a restricted region of one substantia nigra of the rat provoked robust circling and a concomitant rise in ipsilateral nigrostriatal dopamine activity, as revealed by a greater accumulation of 3,4-dihydroxyphenylacetic acid and homovanillic acid in the caudate-putamen together with depleted nigral dopamine concentrations. |
1986-03-21 |
2023-08-11 |
rat |
| I C Kilpatrick, M S Starr, M Summerhaye. Brain dopamine activity following intranigral or intrathalamic drug injections in the rat. Brain research bulletin. vol 15. issue 6. 1986-03-21. PMID:3910169. |
on the other hand, focal application of bicuculline to the substantia nigra or ventromedial thalamus, or intrathalamic kainate, all evoked a closely similar and vigorous hypermotility (not circling) that could not be correlated with the assorted changes in dopamine utilisation occurring in the substantia nigra, caudate-putamen or nucleus accumbens, either uni- or bilaterally. |
1986-03-21 |
2023-08-11 |
rat |
| H Nissbrandt, E Pileblad, A Carlsso. Evidence for dopamine release and metabolism beyond the control of nerve impulses and dopamine receptors in rat substantia nigra. The Journal of pharmacy and pharmacology. vol 37. issue 12. 1986-03-20. PMID:2868096. |
evidence for dopamine release and metabolism beyond the control of nerve impulses and dopamine receptors in rat substantia nigra. |
1986-03-20 |
2023-08-11 |
rat |
| H Nissbrandt, E Pileblad, A Carlsso. Evidence for dopamine release and metabolism beyond the control of nerve impulses and dopamine receptors in rat substantia nigra. The Journal of pharmacy and pharmacology. vol 37. issue 12. 1986-03-20. PMID:2868096. |
in rat substantia nigra a biphasic disappearance curve of dopamine (da) was seen after tyrosine hydroxylase inhibition by alpha-methyl-p-tyrosine (alpha-mt): the initial phase had a fast turnover and a half life of 0.5 h and the later phase had an extremely slow turnover. |
1986-03-20 |
2023-08-11 |
rat |
| J O Rinne, J K Rinne, K Laakso, P Lönnberg, U K Rinn. Dopamine D-1 receptors in the parkinsonian brain. Brain research. vol 359. issue 1-2. 1986-01-24. PMID:2934111. |
dopamine d-1 receptors were analyzed in the caudate nucleus, putamen, pallidum, substantia nigra and nucleus accumbens in 20 patients with parkinson's disease and in 18 age-matched controls by the binding of [3h]flupenthixol. |
1986-01-24 |
2023-08-11 |
Not clear |