| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Paturle, D Fage, O Fourrier, P Vernier, C Feuerstein, P Demenge, B Scatto. Cortical ablation fails to influence striatal dopamine target cell supersensitivity induced by nigrostriatal denervation in the rat. Brain research. vol 402. issue 2. 1987-05-15. PMID:3828803. |
the possible influence of the corticostriatal (glutamatergic) pathway on denervation-induced striatal dopamine target cell supersensitivity has been investigated in the rat by measuring the changes in striatal acetylcholine levels induced by the dopamine agonist pergolide and the basal dopamine d2-receptor density after combined 6-hydroxydopamine-induced lesion of the substantia nigra and cortical ablation. |
1987-05-15 |
2023-08-11 |
rat |
| M L Bouthenet, M P Martres, N Sales, J C Schwart. A detailed mapping of dopamine D-2 receptors in rat central nervous system by autoradiography with [125I]iodosulpride. Neuroscience. vol 20. issue 1. 1987-05-11. PMID:2882443. |
d-2 receptors in substantia nigra (pars compacta or reticulata) and ventral tegmental area were strongly reduced after injections of the neurotoxin 6-hydroxydopamine into the medial forebrain bundle, suggesting their major localization on dendrites and perikarya of dopamine neurons. |
1987-05-11 |
2023-08-11 |
rat |
| J F Plantjé, H W Steinbusch, J Schipper, F A Dijcks, P F Verheijden, J C Stoo. D-2 dopamine-receptors regulate the release of [3H]dopamine in rat cortical regions showing dopamine immunoreactive fibers. Neuroscience. vol 20. issue 1. 1987-05-11. PMID:2951613. |
therefore it is our conclusion that d-2 receptors regulate the release of dopamine from dopaminergic neurons originating in the ventral tegmental area as well as in the substantia nigra. |
1987-05-11 |
2023-08-11 |
rat |
| E H Lee, S L Huang, C Y Cha. Association between the behavioral and neurochemical effects of amphetamine: hemispheric asymmetry study. Life sciences. vol 40. issue 14. 1987-05-04. PMID:2882400. |
behaviorally, amphetamine also decreased l-r asymmetry of the spontaneous turning behavior in rats and this latter effect is most closely associated with the reductions of dopamine and norepinephrine asymmetries in the substantia nigra and reduction of norepinephrine asymmetry in the locus coeruleus. |
1987-05-04 |
2023-08-11 |
rat |
| M J Perlo. Brain grafting as a treatment for Parkinson's disease. Neurosurgery. vol 20. issue 2. 1987-04-30. PMID:3550516. |
some clinical manifestations of this illness are correlated with pathological changes in the substantia nigra and with a loss of dopamine in the nigra and striatum. |
1987-04-30 |
2023-08-11 |
human |
| D J Sirinathsinghji, P E Whittington, A R Audsle. Neurochemical changes in the substantiae nigrae and caudate nuclei following acute unilateral intranigral infusions of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Brain research. vol 399. issue 2. 1987-04-27. PMID:2435361. |
there were pronounced increases in the levels of dopamine (da), dihydroxyphenylacetic acid (dopac) and homovanillic acid (hva) in the ipsilateral substantia nigra and a significant decrease in the levels of da in the ipsilateral caudate nucleus while opposite changes occurred in the contralateral substantia nigra and caudate nucleus. |
1987-04-27 |
2023-08-11 |
rat |
| M Shibuya, N Arita, Y L Yamamot. Regional differences in local cerebral blood flow (LCBF) and glucose utilization (LCGU) in the basal ganglia after occlusion of the middle cerebral artery in rats. Journal of neural transmission. vol 68. issue 3-4. 1987-04-27. PMID:3559540. |
in contrast to the unanimous decrease of lcbf in the ipsilateral cortices and the lateral striatum, complexed changes in lcgu were found in not only the cortex and striatum but also in many other subcortical regions which were closely related to the distribution of the mesencephalic dopamine neurons, such as globus pallidus, substantia nigra, subthalamic nucleus, nucleus accumbens, olfactory tubercle and lateral habenular nucleus. |
1987-04-27 |
2023-08-11 |
rat |
| R Hargraves, W J Free. Chronic intrastriatal dopamine infusions in rats with unilateral lesions of the substantia nigra. Life sciences. vol 40. issue 10. 1987-04-21. PMID:3821366. |
chronic intrastriatal dopamine infusions in rats with unilateral lesions of the substantia nigra. |
1987-04-21 |
2023-08-11 |
rat |
| E Pileblad, G Engber. GBR 13098, a selective dopamine uptake inhibitor; behavioural, biochemical and electrophysiological studies. Naunyn-Schmiedeberg's archives of pharmacology. vol 334. issue 4. 1987-04-20. PMID:2950328. |
did not alter the spontaneous firing rate of dopamine neurons in the substantia nigra zona compacta. |
1987-04-20 |
2023-08-11 |
rat |
| E Pileblad, G Engber. GBR 13098, a selective dopamine uptake inhibitor; behavioural, biochemical and electrophysiological studies. Naunyn-Schmiedeberg's archives of pharmacology. vol 334. issue 4. 1987-04-20. PMID:2950328. |
however, pretreatment with the drug (20 mg/kg, i.p., 10-30 min) enhanced the inhibitory response of microiontophoretically applied dopamine onto the dopamine neurons of substantia nigra. |
1987-04-20 |
2023-08-11 |
rat |
| E Pileblad, G Engber. GBR 13098, a selective dopamine uptake inhibitor; behavioural, biochemical and electrophysiological studies. Naunyn-Schmiedeberg's archives of pharmacology. vol 334. issue 4. 1987-04-20. PMID:2950328. |
present electrophysiological data are in line with the existence of a somatic or dendritic uptake system of dopamine within the substantia nigra but do not support the notion that the impulse activity of nigral dopamine neurons is regulated via a striatonigral feedback pathway. |
1987-04-20 |
2023-08-11 |
rat |
| C A Altar, R E Heikkila, L Manzino, M R Marie. 1-Methyl-4-phenylpyridine (MPP+): regional dopamine neuron uptake, toxicity, and novel rotational behavior following dopamine receptor proliferation. European journal of pharmacology. vol 131. issue 2-3. 1987-04-07. PMID:3493157. |
[3h]mpp+ was transported by the high-affinity dopamine uptake system equally in the caudate-putamen (cp), nucleus accumbens (na) and olfactory tubercle (ot), and to a lesser extent in the substantia nigra. |
1987-04-07 |
2023-08-11 |
rat |
| R Romo, A Chéramy, G Godeheu, J Glowinsk. In vivo presynaptic control of dopamine release in the cat caudate nucleus--III. Further evidence for the implication of corticostriatal glutamatergic neurons. Neuroscience. vol 19. issue 4. 1987-04-06. PMID:2881228. |
in confirmation of previous results, experiments in halothane-anaesthetized cats implanted with push-pull cannulae showed that the unilateral application of gaba (10(-5) m for 30 min) into the left thalamic motor nuclei (either ventralis medialis, or ventralis lateralis) markedly stimulated the release of [3h]dopamine continuously synthesized from [3h]tyrosine in both caudate nuclei and in the contralateral substantia nigra. |
1987-04-06 |
2023-08-11 |
cat |
| R Romo, A Chéramy, G Godeheu, J Glowinsk. In vivo presynaptic control of dopamine release in the cat caudate nucleus--III. Further evidence for the implication of corticostriatal glutamatergic neurons. Neuroscience. vol 19. issue 4. 1987-04-06. PMID:2881228. |
single unit recordings of dopamine cells in the contralateral substantia nigra indicated that the increased release of [3h]dopamine from dendrites evoked by the application of gaba (10(-5)m) into ventralis medialis-ventralis lateralis was associated with a reduction in the firing rate of dopamine cells. |
1987-04-06 |
2023-08-11 |
cat |
| R Romo, A Chéramy, G Godeheu, J Glowinsk. In vivo presynaptic control of dopamine release in the cat caudate nucleus--I. Opposite changes in neuronal activity and release evoked from thalamic motor nuclei. Neuroscience. vol 19. issue 4. 1987-04-06. PMID:3029624. |
halothane-anaesthetized cats implanted with three push-pull cannulae were used to estimate the effects of gamma-aminobutyric acid (gaba) application (either 10(-3) m or 10(-5) m) into the left motor nuclei of the thalamus (either ventralis medialis, or ventralis lateralis) on the firing rate of dopamine cells in the left substantia nigra (caudomedial part) and on the release of [3h]dopamine continuously synthesized from [3h]tyrosine, in the left substantia nigra (caudomedial part) and the left caudate nucleus. |
1987-04-06 |
2023-08-11 |
cat |
| R Romo, A Chéramy, G Godeheu, J Glowinsk. In vivo presynaptic control of dopamine release in the cat caudate nucleus--I. Opposite changes in neuronal activity and release evoked from thalamic motor nuclei. Neuroscience. vol 19. issue 4. 1987-04-06. PMID:3029624. |
preliminary experiments were performed to establish the electrophysiological characteristics of dopamine cells and non-dopamine cells in the pars compacta (mediocaudal part of substantia nigra) in groups of animals with the electrode inserted within the nigral push-pull cannula or with the electrode inserted in the absence of a push-pull cannula. |
1987-04-06 |
2023-08-11 |
cat |
| R Romo, A Chéramy, G Godeheu, J Glowinsk. In vivo presynaptic control of dopamine release in the cat caudate nucleus--I. Opposite changes in neuronal activity and release evoked from thalamic motor nuclei. Neuroscience. vol 19. issue 4. 1987-04-06. PMID:3029624. |
in addition both the intravenous injection of amphetamine or its local application (10(-6) m) in the substantia nigra inhibited the firing rate of dopamine cells. |
1987-04-06 |
2023-08-11 |
cat |
| R Romo, A Chéramy, G Godeheu, J Glowinsk. In vivo presynaptic control of dopamine release in the cat caudate nucleus--I. Opposite changes in neuronal activity and release evoked from thalamic motor nuclei. Neuroscience. vol 19. issue 4. 1987-04-06. PMID:3029624. |
single unit activity of dopamine cells was also inhibited and [3h]dopamine release was reduced in the caudate nucleus and increased in the substantia nigra. |
1987-04-06 |
2023-08-11 |
cat |
| R Romo, A Chéramy, G Godeheu, J Glowinsk. In vivo presynaptic control of dopamine release in the cat caudate nucleus--I. Opposite changes in neuronal activity and release evoked from thalamic motor nuclei. Neuroscience. vol 19. issue 4. 1987-04-06. PMID:3029624. |
when gaba was applied at 10(-5) m for 30 min into the ventralis medialis-ventralis lateralis, multi-unit activity of thalamic cells was increased, single-unit activity of dopamine cells was inhibited and [3h]dopamine release was enhanced in the ipsilateral caudate nucleus and not affected in the left substantia nigra, demonstrating that in this situation the release of dopamine from nerve terminals was not dependent on the firing rate of dopamine cells. |
1987-04-06 |
2023-08-11 |
cat |
| J H Carlson, D A Bergstrom, J R Walter. Stimulation of both D1 and D2 dopamine receptors appears necessary for full expression of postsynaptic effects of dopamine agonists: a neurophysiological study. Brain research. vol 400. issue 2. 1987-04-02. PMID:2880637. |
the abilities of 4 dopamine agonists to inhibit the tonic single unit activity of substantia nigra dopamine neurons and stimulate tonic activity of globus pallidus neurons were compared to study the agonists' effects on pre- and postsynaptic dopamine receptors, respectively. |
1987-04-02 |
2023-08-11 |
Not clear |