| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W C Low, L C Triarhou, Y Kaseda, J Norton, B Ghett. Functional innervation of the striatum by ventral mesencephalic grafts in mice with inherited nigrostriatal dopamine deficiency. Brain research. vol 435. issue 1-2. 1988-03-10. PMID:2892576. |
weaver mutant mice are characterized by a decrease in striatal dopamine (da), which is associated with a progressive loss of da neurones in the substantia nigra. |
1988-03-10 |
2023-08-11 |
mouse |
| G E Meredith, W J Smeet. Immunocytochemical analysis of the dopamine system in the forebrain and midbrain of Raja radiata: evidence for a substantia nigra and ventral tegmental area in cartilaginous fish. The Journal of comparative neurology. vol 265. issue 4. 1988-02-26. PMID:3429712. |
in the mesencephalon, two distinct cell masses are found, which on the basis of their immunoreactivity for dopamine and their location, may be homologous to the substantia nigra and ventral tegmental area of other vertebrates. |
1988-02-26 |
2023-08-11 |
Not clear |
| S R Wachtel, F J Whit. Electrophysiological effects of BMY 14802, a new potential antipsychotic drug, on midbrain dopamine neurons in the rat: acute and chronic studies. The Journal of pharmacology and experimental therapeutics. vol 244. issue 1. 1988-02-24. PMID:2891845. |
the present experiments compared the ability of a new potential antipsychotic drug, bmy 14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine- butanol), to alter the electrophysiological activity of midbrain dopamine (da) neurons in the rat substantia nigra (a9) and ventral tegmental area (a10). |
1988-02-24 |
2023-08-11 |
rat |
| C Gauchy, M L Kemel, M Desban, R Romo, J Glowinski, M J Besso. The role of dopamine released from distal and proximal dendrites of nigrostriatal dopaminergic neurons in the control of GABA transmission in the thalamic nucleus ventralis medialis in the cat. Neuroscience. vol 22. issue 3. 1988-01-20. PMID:3683856. |
amphetamine was applied in the pars reticulata or pars compacta of the substantia nigra in order to determine the role of dopamine released from distal or proximal dendrites of dopaminergic cells in the control of gabaergic transmission in the nucleus ventralis medialis of the thalamus. |
1988-01-20 |
2023-08-11 |
cat |
| M Guttma. Receptors in the basal ganglia. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 14. issue 3 Suppl. 1988-01-13. PMID:2824009. |
in the substantia nigra (sn), receptors have been identified for somatostatin, neurotensin, substance p, glycine, benzodiazepine and gaba, opiates, dopamine, angiotensin converting enzyme (ace) and serotonin. |
1988-01-13 |
2023-08-11 |
Not clear |
| R E Heikkila, P K Sonsall. The use of the MPTP-treated mouse as an animal model of parkinsonism. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 14. issue 3 Suppl. 1988-01-13. PMID:3499967. |
for example, c57 black mice treated with mptp exhibit a large decrement in the neostriatal content of dopamine and its metabolites, a marked reduction in the capacity of neostriatal synaptosomal preparations to accumulate [3h]dopamine, a large decrease in neostriatal tyrosine hydroxylase activity, a marked loss of nerve cells in the zona compacta of the substantia nigra, and pronounced behavioral deficits. |
1988-01-13 |
2023-08-11 |
mouse |
| A Studer, W Schult. The catecholamine uptake inhibitor nomifensine depresses impulse activity of dopamine neurons in mouse substantia nigra. Neuroscience letters. vol 80. issue 2. 1988-01-11. PMID:3683979. |
the catecholamine uptake inhibitor nomifensine depresses impulse activity of dopamine neurons in mouse substantia nigra. |
1988-01-11 |
2023-08-11 |
mouse |
| A Studer, W Schult. The catecholamine uptake inhibitor nomifensine depresses impulse activity of dopamine neurons in mouse substantia nigra. Neuroscience letters. vol 80. issue 2. 1988-01-11. PMID:3683979. |
systemic administration of the catecholamine uptake inhibitor nomifensine (nom) in doses of 20-36 mg/kg strongly depressed the discharge rate of dopamine (da) neurons in the substantia nigra of mice for more than 2-3 h. this effect was fully reverted by the systemically administered da receptor antagonist haloperidol. |
1988-01-11 |
2023-08-11 |
mouse |
| S J Li, S P Sivam, J F McGinty, Y S Huang, J S Hon. Dopaminergic regulation of tachykinin metabolism in the striatonigral pathway. The Journal of pharmacology and experimental therapeutics. vol 243. issue 2. 1988-01-04. PMID:2445959. |
activation of dopamine receptors by subacute administration of apomorphine (apo; 5 mg/kg s.c. twice daily for 7 days) significantly increased striatonigral substance p-like immunoreactivity (sp-li; 73% over control in striatum, 63% over control in substantia nigra) and substance k-like immunoreactivity (49% over control in striatum, 15% over control in substantia nigra). |
1988-01-04 |
2023-08-11 |
rat |
| W G Kuhr, R M Wightman, G V Rebe. Dopaminergic neurons: simultaneous measurements of dopamine release and single-unit activity during stimulation of the medial forebrain bundle. Brain research. vol 418. issue 1. 1987-12-09. PMID:3499205. |
dopamine units, verified by histology to be in the zona compacta of the substantia nigra, were identified by previously established electrophysiological criteria. |
1987-12-09 |
2023-08-11 |
rat |
| b' N A Uranova, O I Levit\\xc3\\xa. [Ultrastructure of the substantia nigra in schizophrenia]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952). vol 87. issue 7. 1987-12-08. PMID:3673380.' |
the compact portion of the substantia nigra containing dopamine neurons was studied at autopsy in schizophrenics and in a control group. |
1987-12-08 |
2023-08-11 |
Not clear |
| S J Kish, K Shannak, O Hornykiewic. Elevated serotonin and reduced dopamine in subregionally divided Huntington's disease striatum. Annals of neurology. vol 22. issue 3. 1987-12-01. PMID:2445259. |
dopamine and serotonin were at control levels in the nucleus accumbens and substantia nigra. |
1987-12-01 |
2023-08-11 |
Not clear |
| S P Sivam, G R Breese, J E Krause, T C Napier, R A Mueller, J S Hon. Neonatal and adult 6-hydroxydopamine-induced lesions differentially alter tachykinin and enkephalin gene expression. Journal of neurochemistry. vol 49. issue 5. 1987-11-23. PMID:2889804. |
furthermore, of the peptides studied, only levels of the tachykinin peptides were differentially altered in the striatum and substantia nigra of the neonatally lesioned rats compared with adult-lesioned rats; therefore, these peptides may be associated with the distinctive behavioral differences between neonatally and adult 6-ohda-lesioned rats given dopamine agonists. |
1987-11-23 |
2023-08-11 |
rat |
| U K Rinne, J O Rinne, J K Rinne, K Laaks. Chemical neurotransmission in the parkinsonian brain. Medical biology. vol 65. issue 2-3. 1987-11-19. PMID:2821331. |
the decreased gaba receptor binding in the parkinsonian substantia nigra possibly reflects the loss of nigral dopamine neurons, since nigral gaba receptors are located on these neurons. |
1987-11-19 |
2023-08-11 |
Not clear |
| J M Trugman, G F Woote. Selective D1 and D2 dopamine agonists differentially alter basal ganglia glucose utilization in rats with unilateral 6-hydroxydopamine substantia nigra lesions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 7. issue 9. 1987-10-21. PMID:3114439. |
selective d1 and d2 dopamine agonists differentially alter basal ganglia glucose utilization in rats with unilateral 6-hydroxydopamine substantia nigra lesions. |
1987-10-21 |
2023-08-11 |
rat |
| L Olson, I Strömberg, M Bygdeman, A C Granholm, B Hoffer, R Freedman, A Seige. Human fetal tissues grafted to rodent hosts: structural and functional observations of brain, adrenal and heart tissues in oculo. Experimental brain research. vol 67. issue 1. 1987-10-21. PMID:3305059. |
catecholamine-rich tissues such as chromaffin cells from the adrenal medulla, sympathetic ganglia, central dopamine neuroblasts from the substantia nigra, and noradrenaline neuroblasts from the locus coeruleus all survived grafting, and in many cases formed nerve fibers that invaded the host iris. |
1987-10-21 |
2023-08-11 |
mouse |
| M Star. Opposing roles of dopamine D1 and D2 receptors in nigral gamma-[3H]aminobutyric acid release? Journal of neurochemistry. vol 49. issue 4. 1987-10-19. PMID:2957468. |
this study examined the effects of dopamine d1 and d2 receptor agonists and antagonists on the spontaneous and calcium-dependent, k+-induced release of gamma-[3h]aminobutyric acid [( 3h]gaba) accumulated by slices of rat substantia nigra. |
1987-10-19 |
2023-08-11 |
rat |
| O Magnusson, B Mohringe, C J Fowle. Comparison of the effects of dopamine D1 and D2 receptor antagonists on rat striatal, limbic and nigral dopamine synthesis and utilisation. Journal of neural transmission. vol 69. issue 3-4. 1987-10-16. PMID:2957465. |
the effects of dopamine (da) antagonists upon da synthesis and utilisation in the rat striatum, olfactory tubercle and substantia nigra have been studied. |
1987-10-16 |
2023-08-11 |
rat |
| R Schwarting, J A Nagel, J P Husto. Asymmetries of brain dopamine metabolism related to conditioned paw usage in the rat. Brain research. vol 417. issue 1. 1987-10-13. PMID:2441821. |
in the second experiment, rats in the paw preference group had a lower dopamine metabolism in the ventral and dorsal striatum, septum, and substantia nigra than did their yoked controls. |
1987-10-13 |
2023-08-11 |
rat |
| H Nissbrandt, A Carlsso. Turnover of dopamine and dopamine metabolites in rat brain: comparison between striatum and substantia nigra. Journal of neurochemistry. vol 49. issue 3. 1987-09-23. PMID:3612134. |
turnover of dopamine and dopamine metabolites in rat brain: comparison between striatum and substantia nigra. |
1987-09-23 |
2023-08-11 |
rat |