| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Kawai, H Takagi, Y Kumoi, S Shiosaka, M Tohyam. Nigrostriatal dopamine neurons receive substance P-ergic inputs in the substantia nigra: application of the immunoelectron microscopic mirror technique to fluorescent double-staining for transmitter-specific projections. Brain research. vol 401. issue 2. 1987-03-30. PMID:2434194. |
nigrostriatal dopamine neurons receive substance p-ergic inputs in the substantia nigra: application of the immunoelectron microscopic mirror technique to fluorescent double-staining for transmitter-specific projections. |
1987-03-30 |
2023-08-11 |
Not clear |
| Y Kawai, H Takagi, Y Kumoi, S Shiosaka, M Tohyam. Nigrostriatal dopamine neurons receive substance P-ergic inputs in the substantia nigra: application of the immunoelectron microscopic mirror technique to fluorescent double-staining for transmitter-specific projections. Brain research. vol 401. issue 2. 1987-03-30. PMID:2434194. |
a direct synaptic contact between nigrostriatal dopamine neurons and substance p axons in the substantia nigra was demonstrated using the immunoelectron microscopic mirror technique combined with the fluorescent double-staining method for transmitter-specific projections. |
1987-03-30 |
2023-08-11 |
Not clear |
| Y Kawai, H Takagi, Y Kumoi, S Shiosaka, M Tohyam. Nigrostriatal dopamine neurons receive substance P-ergic inputs in the substantia nigra: application of the immunoelectron microscopic mirror technique to fluorescent double-staining for transmitter-specific projections. Brain research. vol 401. issue 2. 1987-03-30. PMID:2434194. |
it appears that substance p afferents directly affect nigrostriatal dopamine neurons in the substantia nigra via the synaptic contacts. |
1987-03-30 |
2023-08-11 |
Not clear |
| J Kor. Release of endogenous amino acids, dopamine, and cyclic AMP from the rat brain: methodological aspects and mutual interferences. Annals of the New York Academy of Sciences. vol 473. 1987-02-19. PMID:3026218. |
locally applied dopamine produced a specific decrease in the release of gamma-aminobutyric acid in both the substantia nigra and in the striatum. |
1987-02-19 |
2023-08-11 |
rat |
| I C Kilpatrick, O T Phillipso. Thalamic control of dopaminergic functions in the caudate-putamen of the rat--I. The influence of electrical stimulation of the parafascicular nucleus on dopamine utilization. Neuroscience. vol 19. issue 3. 1987-02-05. PMID:3796823. |
tissue concentrations of dopamine and its two major metabolites, 3,4-dihydroxyphenylacetic acid and 4-hydroxy-3-methoxyphenylacetic acid, were assayed by a high performance liquid chromatographic technique in samples of caudate-putamen complex, nucleus accumbens, prefrontal cortex and substantia nigra. |
1987-02-05 |
2023-08-11 |
rat |
| I C Kilpatrick, O T Phillipso. Thalamic control of dopaminergic functions in the caudate-putamen of the rat--I. The influence of electrical stimulation of the parafascicular nucleus on dopamine utilization. Neuroscience. vol 19. issue 3. 1987-02-05. PMID:3796823. |
electrical stimulation of one parafascicular nucleus produced further bilateral elevations of dopamine utilization in the caudate-putamen complex without altering these parameters in the substantia nigra. |
1987-02-05 |
2023-08-11 |
rat |
| I C Kilpatrick, M W Jones, B J Johnson, J Cornwall, O T Phillipso. Thalamic control of dopaminergic functions in the caudate-putamen of the rat--II. Studies using ibotenic acid injection of the parafascicular-intralaminar nuclei. Neuroscience. vol 19. issue 3. 1987-02-05. PMID:3796824. |
dopamine utilization was measured at 4 h, 18 h, and 7 days after operation in microdissected tissue from caudate-putamen, substantia nigra, and nucleus accumbens. |
1987-02-05 |
2023-08-11 |
rat |
| I C Kilpatrick, M W Jones, B J Johnson, J Cornwall, O T Phillipso. Thalamic control of dopaminergic functions in the caudate-putamen of the rat--II. Studies using ibotenic acid injection of the parafascicular-intralaminar nuclei. Neuroscience. vol 19. issue 3. 1987-02-05. PMID:3796824. |
these changes were independent of dopamine utilization ratios recorded in the substantia nigra, which showed no change either ipsilateral or contralateral to the injection. |
1987-02-05 |
2023-08-11 |
rat |
| I C Kilpatrick, M W Jones, B J Johnson, J Cornwall, O T Phillipso. Thalamic control of dopaminergic functions in the caudate-putamen of the rat--II. Studies using ibotenic acid injection of the parafascicular-intralaminar nuclei. Neuroscience. vol 19. issue 3. 1987-02-05. PMID:3796824. |
furthermore, since the changes found occurred in the absence of changes in utilization ratios in the substantia nigra, the mechanisms whereby thalamus regulates dopamine release may be exerted via a local circuit and/or a presynaptic mechanism in the region of dopamine terminals. |
1987-02-05 |
2023-08-11 |
rat |
| J Grenhoff, G Aston-Jones, T H Svensso. Nicotinic effects on the firing pattern of midbrain dopamine neurons. Acta physiologica Scandinavica. vol 128. issue 3. 1987-01-22. PMID:3788613. |
dopamine cells of the zona compacta, substantia nigra (zc-sn) and the ventral tegmental area (vta) were identified by their characteristic action potentials, antidromic stimulation methodology and conventional histological procedures. |
1987-01-22 |
2023-08-11 |
rat |
| S Lindgre. Effects of KCl-induced depolarization on the GABA concentration in the corpus striatum and in the substantia nigra. Journal of neural transmission. vol 66. issue 3-4. 1987-01-06. PMID:3783143. |
the effects of potassium ion depolarization on the concentration, the synthesis and the utilization of gaba as well as the effects on the concentrations of glutamine, dopamine (da) and dopac in the substantia nigra and in the corpus striatum of the rat were investigated. |
1987-01-06 |
2023-08-11 |
rat |
| J R Hotson, E B Langston, J W Langsto. Saccade responses to dopamine in human MPTP-induced parkinsonism. Annals of neurology. vol 20. issue 4. 1986-12-29. PMID:3491578. |
depletion of dopamine content in the substantia nigra resulting from 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (mptp) toxicity produces parkinsonism. |
1986-12-29 |
2023-08-11 |
human |
| T N Ferraro, G T Golden, M DeMattei, T A Hare, R G Fariell. Effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on levels of glutathione in the extrapyramidal system of the mouse. Neuropharmacology. vol 25. issue 9. 1986-12-12. PMID:2430229. |
depletion of striatal dopamine and metabolites in mptp-treated mice is accompanied by depletion of glutathione (gsh) in the substantia nigra (sn). |
1986-12-12 |
2023-08-11 |
mouse |
| S N Habe. Neurotransmitters in the human and nonhuman primate basal ganglia. Human neurobiology. vol 5. issue 3. 1986-12-09. PMID:2876974. |
these include: the well-described terminal fields in the striatum which originate from the brain stem and contain the monoamines, dopamine and serotonin; amino acid containing axons projecting from the cortex and thalamus; striatal cholinergic and peptide-positive interneurons; and amino acid and peptide containing projection neurons to the globus pallidus and substantia nigra. |
1986-12-09 |
2023-08-11 |
human |
| G Jonsson, E Nwanze, J Luthman, E Sundströ. Effect of MPTP and its pyridinium metabolites on monoamine uptake and on central catecholamine neurons in mice. Acta physiologica Scandinavica. vol 128. issue 2. 1986-12-05. PMID:3535380. |
intracerebral injection of mpp+ into substantia nigra produced an almost complete disappearance of dopamine in striatum and noradrenaline in cerebral cortex, while injection of mptp or mpdp+ had no or only moderate catecholamine-depleting effects. |
1986-12-05 |
2023-08-11 |
mouse |
| M Van den Buuse, H D Veldhuis, D H Versteeg, W De Jon. Substantia nigra lesions attenuate the development of hypertension and behavioural hyperreactivity in spontaneously hypertensive rats. Pharmacology, biochemistry, and behavior. vol 25. issue 2. 1986-11-21. PMID:3763656. |
depletion of striatal dopamine by lesions in the substantia nigra of spontaneously hypertensive rats (shr) was associated with an inhibition of the development of hypertension. |
1986-11-21 |
2023-08-11 |
rat |
| K Kamata, A Sugimoto, T Kameyam. Effect of chronic haloperidol on dopamine release following microinjection of GABA into the substantia nigra zona reticulata in the rat. Brain research. vol 380. issue 1. 1986-11-13. PMID:3756464. |
effect of chronic haloperidol on dopamine release following microinjection of gaba into the substantia nigra zona reticulata in the rat. |
1986-11-13 |
2023-08-11 |
rat |
| K Kamata, A Sugimoto, T Kameyam. Effect of chronic haloperidol on dopamine release following microinjection of GABA into the substantia nigra zona reticulata in the rat. Brain research. vol 380. issue 1. 1986-11-13. PMID:3756464. |
to investigate the influence of the striatonigral gamma-aminobutyric acid (gaba) system on the nigrostriatal dopamine (da) system, the release of da and/or 3,4-dihydroxyphenylacetic acid in the striatum ipsilateral to the injection side was examined by in vivo voltammetry following microinjection of gaba into the substantia nigra zona reticulata (snr). |
1986-11-13 |
2023-08-11 |
rat |
| W G Erwin, T F Turc. Current concepts in clinical therapeutics: Parkinson's disease. Clinical pharmacy. vol 5. issue 9. 1986-11-03. PMID:3530616. |
the clinical features of parkinsonism result from a depletion in dopaminergic transmission in the corpus striatum; the dopamine deficiency is caused by a loss of melanin-containing nerve cells within the substantia nigra and locus ceruleus. |
1986-11-03 |
2023-08-11 |
Not clear |
| A A Grace, B S Bunne. Induction of depolarization block in midbrain dopamine neurons by repeated administration of haloperidol: analysis using in vivo intracellular recording. The Journal of pharmacology and experimental therapeutics. vol 238. issue 3. 1986-10-23. PMID:3746660. |
acute administration of the antipsychotic drug haloperidol causes an increase in the firing rate and in the proportion of spontaneously active dopamine neurons in the substantia nigra. |
1986-10-23 |
2023-08-11 |
rat |