| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L A Chiodo, B S Bunne. Electrophysiological studies on EMD 23 448, an indolyl-3-butylamine, in the rat: a putative selective dopamine autoreceptor agonist. Neuropharmacology. vol 22. issue 9. 1983-12-21. PMID:6138728. |
single unit electrophysiological and microiontophoretic techniques were used to study the effects of a putative selective dopamine autoreceptor agonist, emd 23 448, an indolyl-3-butylamine on the activity of both dopamine neurons in the substantia nigra and dopamine-sensitive neurons in the caudate nucleus. |
1983-12-21 |
2023-08-12 |
rat |
| R D Huffman, M K Tick. The effects of chronic haloperidol administration on GABA receptor binding. Pharmacology, biochemistry, and behavior. vol 19. issue 2. 1983-12-20. PMID:6314387. |
these observations suggest that blockade of dopamine receptors in the striatum by haloperidol results in a compensatory decrease in the activity of the gabaergic strionigral system that leads to an increase in the number of gaba binding sites within the substantia nigra. |
1983-12-20 |
2023-08-12 |
rat |
| G Gianutsos, G M Carlson, J G Godfre. Drug-induced changes in motor activity after selective MAO inhibition. Pharmacology, biochemistry, and behavior. vol 19. issue 2. 1983-12-20. PMID:6634874. |
the clorgyline pretreatment resulted in larger increases in brain dopamine concentrations (in the striatum, olfactory tubercles and in the area containing the substantia nigra) than did mao-b inhibition. |
1983-12-20 |
2023-08-12 |
mouse |
| J D Miller, J Farber, P Gatz, H Roffwarg, D C Germa. Activity of mesencephalic dopamine and non-dopamine neurons across stages of sleep and walking in the rat. Brain research. vol 273. issue 1. 1983-11-23. PMID:6616218. |
single unit activity of dopamine and non-dopamine neurons in the substantia nigra and ventral tegmental area was recorded across stages of sleep and waking in the rat. |
1983-11-23 |
2023-08-12 |
rat |
| P Piccardi, F Bernardi, Z Rossetti, G Corsin. Effect of estrogens on dopamine autoreceptors in male rats. European journal of pharmacology. vol 91. issue 1. 1983-11-23. PMID:6617733. |
recent electrophysiological data, showing that estrogens significantly attenuate the ability of apomorphine to inhibit the firing activity of type b dopamine neurons in the rat substantia nigra, suggest that these hormones may also induce subsensitivity of da autoreceptors. |
1983-11-23 |
2023-08-12 |
rat |
| N E Andén, M Grabowska-Andén, S Lindgren, U Thornströ. Synthesis rate of dopamine: difference between corpus striatum and limbic system as a possible explanation of variations in reactions to drugs. Naunyn-Schmiedeberg's archives of pharmacology. vol 323. issue 3. 1983-11-23. PMID:6621714. |
the lower dopamine synthesis rate in the latter region may be due to a negative neuronal feedback from the corpus striatum to the substantia nigra. |
1983-11-23 |
2023-08-12 |
rat |
| F J White, R Y Wan. Differential effects of classical and atypical antipsychotic drugs on A9 and A10 dopamine neurons. Science (New York, N.Y.). vol 221. issue 4615. 1983-09-23. PMID:6136093. |
prolonged treatment with classical antipsychotic drugs decreased the number of spontaneously active dopamine neurons in both the substantia nigra (a9) and the ventral tegmental area (a10) of the rat brain. |
1983-09-23 |
2023-08-12 |
rat |
| W J Freed, F Karoum, H E Spoor, J M Morihisa, L Olson, R J Wyat. Catecholamine content of intracerebral adrenal medulla grafts. Brain research. vol 269. issue 1. 1983-09-23. PMID:6683581. |
in hosts with substantia nigra lesions, concentrations of dopamine in the adrenal medulla grafts were decreased. |
1983-09-23 |
2023-08-12 |
Not clear |
| L A Chiodo, A R Caggiul. Substantia nigra dopamine neurons: alterations in basal discharge rates and autoreceptor sensitivity induced by estrogen. Neuropharmacology. vol 22. issue 5. 1983-09-20. PMID:6877536. |
substantia nigra dopamine neurons: alterations in basal discharge rates and autoreceptor sensitivity induced by estrogen. |
1983-09-20 |
2023-08-12 |
human |
| C A Seyfrie. Dopamine uptake inhibiting versus dopamine releasing properties of fencamfamine: an in vitro study. Biochemical pharmacology. vol 32. issue 15. 1983-09-09. PMID:6136281. |
to elucidate its mechanism of action, the effects of fencamfamine, a norcamphanethylamine derivative, were studied in vitro on the release of newly accumulated dopamine in superfusion experiments using slices of rat corpus striatum and substantia nigra in comparison to nomifensine and d-amphetamine. |
1983-09-09 |
2023-08-12 |
rat |
| R S Burns, C C Chiueh, S P Markey, M H Ebert, D M Jacobowitz, I J Kopi. A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proceedings of the National Academy of Sciences of the United States of America. vol 80. issue 14. 1983-09-09. PMID:6192438. |
nmptp treatment decreases the release of dopamine and dopamine accumulates in swollen, distorted axons in the nigrostriatal pathway just above the substantia nigra, followed by severe nerve cell loss in the pars compacta of the substantia nigra and a marked reduction in the dopamine content of the striatum. |
1983-09-09 |
2023-08-12 |
monkey |
| R E McClung, J Woo. Ultrastructural differentiation within the central nervous system between indolamines and catecholamines by energy dispersive X-ray analysis following paraformaldehyde pretreatment. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 31. issue 8. 1983-08-26. PMID:6408162. |
dense bodies containing high amounts of chrome were localized in the perikarya of substantia nigra and dorsal raphe neurons following the cytochemical reaction of endogenous dopamine and serotonin (respectively) with glutaraldehyde-dichromate (gdc). |
1983-08-26 |
2023-08-12 |
Not clear |
| S G Howard, E Garcia-Ril. Effects of electrical stimulation on acetylcholine synthesis in cat caudate nucleus. Brain research bulletin. vol 10. issue 4. 1983-08-26. PMID:6860971. |
electrical stimulation of the substantia nigra, which increases the release of dopamine, produced a decrease in endogenous ach and the newly synthesized deuterium-labeled ach. |
1983-08-26 |
2023-08-12 |
cat |
| A Chéramy, M F Chesselet, R Romo, V Leviel, J Glowinsk. Effects of unilateral electrical stimulation of various thalamic nuclei on the release of dopamine from dendrites and nerve terminals of neurons of the two nigrostriatal dopaminergic pathways. Neuroscience. vol 8. issue 4. 1983-08-11. PMID:6866262. |
a reduction of [3h]dopamine release occurred in the four structures or only in the contralateral substantia nigra and caudate nucleus following the stimulation of the parafascicularis nucleus and the adjacent posterior part of the nucleus centrum medianum or of the nucleus centralis lateralis and the adjacent paralaminar part of the nucleus medialis dorsalis, respectively. |
1983-08-11 |
2023-08-12 |
Not clear |
| A Chéramy, M F Chesselet, R Romo, V Leviel, J Glowinsk. Effects of unilateral electrical stimulation of various thalamic nuclei on the release of dopamine from dendrites and nerve terminals of neurons of the two nigrostriatal dopaminergic pathways. Neuroscience. vol 8. issue 4. 1983-08-11. PMID:6866262. |
the stimulation of the anterior part of the nucleus centrum medianum, which in contrast to other thalamic nuclei examined, receives few nigral inputs, selectively enhanced [3h]dopamine release in the contralateral substantia nigra. |
1983-08-11 |
2023-08-12 |
Not clear |
| K Fuxe, L Calza, F Benfenati, I Zini, L F Agnat. Quantitative autoradiographic localization of [3H]imipramine binding sites in the brain of the rat: relationship to ascending 5-hydroxytryptamine neuron systems. Proceedings of the National Academy of Sciences of the United States of America. vol 80. issue 12. 1983-07-15. PMID:6304742. |
high labeling is observed in the midbrain raphe nuclei, the areas of the dopamine cell groups of the substantia nigra and of the ventral tegmental area of tsai, the ventral amygdaloid nucleus, the midline thalamic area, and parts of the hypothalmus. |
1983-07-15 |
2023-08-12 |
rat |
| M S Starr, M Summerhayes, I C Kilpatric. Interactions between dopamine and gamma-aminobutyrate in the substantia nigra: implications for the striatonigral output hypothesis. Neuroscience. vol 8. issue 3. 1983-07-08. PMID:6856085. |
interactions between dopamine and gamma-aminobutyrate in the substantia nigra: implications for the striatonigral output hypothesis. |
1983-07-08 |
2023-08-12 |
rat |
| B Scatton, H Simon, M Le Moal, S Bischof. Origin of dopaminergic innervation of the rat hippocampal formation. Neuroscience letters. vol 18. issue 2. 1983-06-23. PMID:7052484. |
the origin of the dopaminergic afferents to the rat hippocampal formation has been investigated by measuring dopamine and dopac contents in this area after electrolytic or chemical lesion of the ventral tegmental area (a10) or substantia nigra (a9). |
1983-06-23 |
2023-08-12 |
rat |
| M S Star. Specificity of GABA as a stimulator of dopamine release in rat substantia nigra. Neuroscience letters. vol 18. issue 1. 1983-06-10. PMID:6133247. |
specificity of gaba as a stimulator of dopamine release in rat substantia nigra. |
1983-06-10 |
2023-08-12 |
rat |
| M S Star. Specificity of GABA as a stimulator of dopamine release in rat substantia nigra. Neuroscience letters. vol 18. issue 1. 1983-06-10. PMID:6133247. |
the effects of amino acids and the benzodiazepine, flurazepam, on spontaneous and potassium-stimulated [3h]dopamine (da) release were studied in slices of rat substantia nigra. |
1983-06-10 |
2023-08-12 |
rat |