| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G de Montis, K Beaumont, F Javoy-Agid, Y Agid, J Constandinidis, A Lowenthal, K G Lloy. Glycine receptors in the human substantia nigra as defined by [3H]strychnine binding. Journal of neurochemistry. vol 38. issue 3. 1982-04-20. PMID:6276509. |
together with previous neurophysiological and neuropharmacological findings, those results support the hypothesis of glycine receptors occurring on dopamine cell bodies and/or dendrites in the substantia nigra. |
1982-04-20 |
2023-08-12 |
human |
| S H Appe. A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism, and Alzheimer disease. Annals of neurology. vol 10. issue 6. 1982-03-13. PMID:6173010. |
in parkinson disease, the neurotrophic failure would be characterized by inability of striatal cells to provide the required dopamine neurotrophic hormone with resulting impairment of substantia nigra cells. |
1982-03-13 |
2023-08-12 |
Not clear |
| S Arbilla, L A Kamal, S Z Lange. Inhibition by apomorphine of the potassium-evoked release of [3H]-gamma-aminobutyric acid from the rat substantia nigra in vitro. British journal of pharmacology. vol 74. issue 2. 1982-03-13. PMID:7317688. |
in vivo administration of haloperidol 0.2 mg/kg antagonized the in vitro inhibition by apomorphine of the k(+)-evoked release of [(3)h]-gaba.5 the results obtained with apomorphine and haloperidol suggest the presence of presynaptic dopamine-like inhibitory receptors in gabaergic nerve terminals.6 dopamine in concentrations ranging up to 300 mum did not modify either the spontaneous or the k(+)-evoked release of [(3)h]-gaba from the substantia nigra. |
1982-03-13 |
2023-08-12 |
rat |
| S Arbilla, L A Kamal, S Z Lange. Inhibition by apomorphine of the potassium-evoked release of [3H]-gamma-aminobutyric acid from the rat substantia nigra in vitro. British journal of pharmacology. vol 74. issue 2. 1982-03-13. PMID:7317688. |
these concentrations of dopamine effectively displaced [(3)h]-dopamine recently taken up into the substantia nigra.7 our results do not support the view that dendritic release of dopamine from the substantia nigra might be involved in the physiological modulation of the spontaneous or the stimulation-evoked release of gaba. |
1982-03-13 |
2023-08-12 |
rat |
| K Gale, M Cas. Dynamic utilization of GABA in substantia nigra: regulation by dopamine and GABA in the striatum, and its clinical and behavioral implications. Molecular and cellular biochemistry. vol 39. 1982-02-22. PMID:6118827. |
dynamic utilization of gaba in substantia nigra: regulation by dopamine and gaba in the striatum, and its clinical and behavioral implications. |
1982-02-22 |
2023-08-12 |
Not clear |
| S B Dunnett, A Björklund, U Stenevi, S D Iverse. Grafts of embryonic substantia nigra reinnervating the ventrolateral striatum ameliorate sensorimotor impairments and akinesia in rats with 6-OHDA lesions of the nigrostriatal pathway. Brain research. vol 229. issue 1. 1982-02-22. PMID:6796195. |
previous studies have shown that transplants of embryonic substantia nigra, which reinnervate the dorsal neostriatum, can compensate for certain, but not all, behavioural deficits induced by unilateral or bilateral destruction of the nigrostriatal dopamine pathways in adult rats. |
1982-02-22 |
2023-08-12 |
rat |
| J A Severson, H H Osterburg, C E Finc. Aging and haloperidol-induced dopamine turnover in the nigro-striatal pathway of C57BL/6J mice. Neurobiology of aging. vol 2. issue 3. 1982-02-12. PMID:7312097. |
dopamine turnover and dopac levels were less in striatum than in substantia nigra; each region had a characteristic dopac/da ratio (nigra, 38%; striatum, 7%); and, dopac levels did not precisely covary with da turnover between regions. |
1982-02-12 |
2023-08-12 |
mouse |
| Z Hahn, Z Karádi, L Lénár. Striatal dopamine levels after unilateral lesions of the substantia nigra: evidence for a contralateral decrease. Acta physiologica Academiae Scientiarum Hungaricae. vol 57. issue 3. 1982-01-28. PMID:6795897. |
striatal dopamine levels after unilateral lesions of the substantia nigra: evidence for a contralateral decrease. |
1982-01-28 |
2023-08-12 |
rat |
| Z Hahn, Z Karádi, L Lénár. Striatal dopamine levels after unilateral lesions of the substantia nigra: evidence for a contralateral decrease. Acta physiologica Academiae Scientiarum Hungaricae. vol 57. issue 3. 1982-01-28. PMID:6795897. |
unilateral electrolytical and chemical (6-hydroxydopamine) lesions in the substantia nigra (sn) of rats were followed 7 days later by considerable bilateral decreases of neostriatal dopamine (da) levels. |
1982-01-28 |
2023-08-12 |
rat |
| J Aceves, A C Cuell. Dopamine release induced by electrical stimulation of microdissected caudate-putamen and substantia nigra of the rat brain. Neuroscience. vol 6. issue 10. 1982-01-28. PMID:7301117. |
dopamine release induced by electrical stimulation of microdissected caudate-putamen and substantia nigra of the rat brain. |
1982-01-28 |
2023-08-12 |
rat |
| G Sperk, M Berger, H Hörtnagl, O Hornykiewic. Kainic acid-induced changes of serotonin and dopamine metabolism in the striatum and substantia nigra of the rat. European journal of pharmacology. vol 74. issue 4. 1982-01-09. PMID:6170518. |
kainic acid-induced changes of serotonin and dopamine metabolism in the striatum and substantia nigra of the rat. |
1982-01-09 |
2023-08-12 |
rat |
| F Héry, J P Ternau. Regulation of release processes in central serotoninergic neurons. Journal de physiologie. vol 77. issue 2-3. 1981-12-22. PMID:6457140. |
the effects of the release of dopamine from dendrites, and that of gaba in the substantia nigra are reported herein. |
1981-12-22 |
2023-08-12 |
Not clear |
| A Dra. Serotonin in the basal ganglia: functions and interactions with other neuronal pathways. Journal de physiologie. vol 77. issue 2-3. 1981-12-22. PMID:7026771. |
behavioral studies show that serotonin, like dopamine, produces asymmetries when administered into the striatum or substantia nigra. |
1981-12-22 |
2023-08-12 |
Not clear |
| A L Jaton, J M Vigouret, A Dravi. [Involvement of serotoninergic mechanisms in the circling behaviour induced by apomorphine and LSD 25 in rats (author's transl)]. Journal de physiologie. vol 77. issue 2-3. 1981-12-22. PMID:7288655. |
a serotoninergic projection from the median raphé nucleus to dopamine neurons in the substantia nigra has been reported. |
1981-12-22 |
2023-08-12 |
rat |
| M T Lin, J J Wu, A Chandra, B L Tsa. Activation of striatal dopamine receptors induces pain inhibition in rats. Journal of neural transmission. vol 51. issue 3-4. 1981-12-21. PMID:7288429. |
in the rat, elevating dopamine content in corpus striatum with electrical stimulation of substantia nigra or direct administration of apomorphine (50-200 micrograms) into the lateral cerebral ventricle or apomorphine (2-10 microgram) into the caudate-putamen complex decreased pain sensitivity (as shown by an increase in the latency to hind-paw lick in the hot plate test). |
1981-12-21 |
2023-08-12 |
rat |
| M T Lin, J J Wu, A Chandra, B L Tsa. Activation of striatal dopamine receptors induces pain inhibition in rats. Journal of neural transmission. vol 51. issue 3-4. 1981-12-21. PMID:7288429. |
on the other hand, lowering dopamine content in corpus striatum with electrolytic destruction of substantia nigra and 6-hydroxydopamine lesions to the substantia nigra, as well as direct injection of haloperidol into the lateral cerebral ventricle or caudate-putamen complex increased pain sensitivity. |
1981-12-21 |
2023-08-12 |
rat |
| S M Wuerthele, W J Freed, L Olson, J Morihisa, L Spoor, R J Wyatt, B J Hoffe. Effect of dopamine agonists and antagonists on the electrical activity of substantia nigra neurons transplanted into the lateral ventricle of the rat. Experimental brain research. vol 44. issue 1. 1981-11-18. PMID:7274357. |
effect of dopamine agonists and antagonists on the electrical activity of substantia nigra neurons transplanted into the lateral ventricle of the rat. |
1981-11-18 |
2023-08-12 |
rat |
| G F Wooten, R C Collin. Metabolic effects of unilateral lesion of the substantia nigra. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 1. issue 3. 1981-10-29. PMID:7264720. |
these results suggest that lesion of the substantia nigra with depletion of striatal dopamine content results in disinhibition of some striatal, and perhaps olfactory cortical, efferents producing increased metabolism and glucose utilization in terminal fields within the globus pallidus and lateral habenular nucleus. |
1981-10-29 |
2023-08-12 |
rat |
| U K Rinn. Treatment of Parkinson's disease: problems with a progressing disease. Journal of neural transmission. vol 51. issue 1-2. 1981-10-25. PMID:7264627. |
post-mortem brain studies have shown that in parkinson's disease there is not only a progressive loss of dopaminergic substantia nigra neurons but there are also significant changes in the striatal dopamine receptors. |
1981-10-25 |
2023-08-12 |
Not clear |
| R G Fariello, O Hornykiewic. Substantia nigra and pentylenetetrazol threshold in rats: correlation with striatal dopamine metabolism. Experimental neurology. vol 65. issue 1. 1981-09-25. PMID:262229. |
substantia nigra and pentylenetetrazol threshold in rats: correlation with striatal dopamine metabolism. |
1981-09-25 |
2023-08-11 |
rat |