| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Browder, D C German, P A Shor. Midbrain dopamine neurons: differential responses to amphetamine isomers. Brain research. vol 207. issue 2. 1981-05-26. PMID:7470912. |
the comparable potencies of the d- and l-isomers on dorsal substantia nigra and ventral tegmental area dopamine neurons may explain, by a dopamine mechanism, the finding that comparable doses of the isomers produce schizophrenic-like symptoms. |
1981-05-26 |
2023-08-12 |
Not clear |
| F Fadda, A Argiolas, M R Melis, G Serr. Effect of acute and chronic ethanol on dopamine synthesis in the caudate nucleus, substantia nigra and frontal cortex. Bollettino della Societa italiana di biologia sperimentale. vol 56. issue 24. 1981-05-21. PMID:7470302. |
effect of acute and chronic ethanol on dopamine synthesis in the caudate nucleus, substantia nigra and frontal cortex. |
1981-05-21 |
2023-08-12 |
rat |
| F Fadda, A Argiolas, M R Melis, G Serr. Effect of acute and chronic ethanol on dopamine synthesis in the caudate nucleus, substantia nigra and frontal cortex. Bollettino della Societa italiana di biologia sperimentale. vol 56. issue 24. 1981-05-21. PMID:7470302. |
a single oral administration of 3.2 g/kg ethanol to normal rats increased 3,4-dihydroxyphenylacetic acid (dopac) content and dopa formation in the caudate nucleus but had no effect in frontal cortex and substantia nigra and did not modify dopamine (da) levels in any of the brain regions analyzed. |
1981-05-21 |
2023-08-12 |
rat |
| F Fadda, A Argiolas, M R Melis, G Serra, S Congi. Effect of ethanol on the metabolism of regional brain dopamine. Bollettino della Societa italiana di biologia sperimentale. vol 56. issue 24. 1981-05-21. PMID:7470303. |
acute oral administration of ethanol (3.2g/kg) to rats increased (dopac) levels in the caudate nucleus, but had no effect on dopac levels in the substantia nigra and frontal cortex and failed to modify dopamine content in any of the above areas. |
1981-05-21 |
2023-08-12 |
rat |
| A Kuruvilla, N J Uretsk. Effect of sodium valproate on motor function regulated by the activation of GABA receptors. Psychopharmacology. vol 72. issue 2. 1981-05-13. PMID:6259678. |
gaba interacts with dopamine functionally in certain areas of the brain involved in motor behavior such as the nucleus accumbens and the substantia nigra. |
1981-05-13 |
2023-08-12 |
rat |
| A Cheramy, V Leviel, J Glowinsk. Dendritic release of dopamine in the substantia nigra. Nature. vol 289. issue 5798. 1981-04-13. PMID:6258083. |
dendritic release of dopamine in the substantia nigra. |
1981-04-13 |
2023-08-12 |
Not clear |
| A Cheramy, V Leviel, J Glowinsk. Dendritic release of dopamine in the substantia nigra. Nature. vol 289. issue 5798. 1981-04-13. PMID:6258083. |
dopamine can be released in the substantia nigra for the dendrites of nigrostriatal dopaminergic neurones, to be involved there in the self-regulation of the dopaminergic cells, to control the release of neurotransmitters from nigral afferent fibres and to influence the activity of nigral non-dopaminergic cells. |
1981-04-13 |
2023-08-12 |
Not clear |
| O Hornykiewic. [Brain dopamine and brain disorders - and what we have learned from these studies (author's transl)]. Wiener klinische Wochenschrift. vol 92. issue 20. 1981-04-13. PMID:7467350. |
two examples are given to illustrate the role of dopamine in brain disorders: a) in parkinson's disease there is a marked deficiency of dopamine in several subcortical brain regions, particularly the striatum (caudate nucleus and putamen) and substantia nigra. |
1981-04-13 |
2023-08-12 |
Not clear |
| J A van der Heyden, K Venema, J Kor. Biphasic and opposite effects of dopamine and apomorphine on endogenous GABA release in the rat substantia nigra. Journal of neurochemistry. vol 34. issue 1. 1981-03-17. PMID:6778956. |
biphasic and opposite effects of dopamine and apomorphine on endogenous gaba release in the rat substantia nigra. |
1981-03-17 |
2023-08-12 |
rat |
| E B Taha, P Redgrav. Neuroleptic suppression of feeding and oral stereotypy following microinjections of carbachol into substantia nigra. Neuroscience letters. vol 20. issue 3. 1981-02-24. PMID:6255380. |
these data are consistent with the hypothesis that cholinergic neurotransmission in the rostral substantia nigra mediating oral responses is afferent to the dopamine systems arising from this area. |
1981-02-24 |
2023-08-12 |
rat |
| L A Chiodo, S M Antelma. Electroconvulsive shock: progressive dopamine autoreceptor subsensitivity independent of repeated treatment. Science (New York, N.Y.). vol 210. issue 4471. 1981-01-26. PMID:6254148. |
repeated electroconvulsive shock, applied to rats, induces a subsensitivity of dopamine autoreceptors located in the substantia nigra as indexed by single-unit electrophysiological techniques. |
1981-01-26 |
2023-08-12 |
rat |
| F Fadda, A Argiolas, M R Melis, G Serra, G L Gess. Differential effect of acute and chronic ethanol on dopamine metabolism in frontal cortex, caudate nucleus and substantia nigra. Life sciences. vol 27. issue 11. 1981-01-26. PMID:7432099. |
differential effect of acute and chronic ethanol on dopamine metabolism in frontal cortex, caudate nucleus and substantia nigra. |
1981-01-26 |
2023-08-12 |
Not clear |
| W J Freed, M J Perlow, F Karoum, A Seiger, L Olson, B J Hoffer, R J Wyat. Restoration of dopaminergic function by grafting of fetal rat substantia nigra to the caudate nucleus: long-term behavioral, biochemical, and histochemical studies. Annals of neurology. vol 8. issue 5. 1981-01-26. PMID:7436393. |
motor deficits produced in rats by unilateral substantia nigra lesions have been found to be reduced by grafts of fetal rat substantia nigra to the dopamine denervated caudate nucleus. |
1981-01-26 |
2023-08-12 |
rat |
| B S Bunney, A A Grace, D W Homme. Changing concepts of nigral dopamine system function within the basal ganglia: relevance to extrapyramidal disorders. Journal of neural transmission. Supplementum. issue 16. 1981-01-16. PMID:6107330. |
rather than dopamine being seen primarily as a major influence on striatal output it is now perhaps best conceptualized as one link in a set of circular pathways, one of whose functions is to modulate nondopaminergic output from the substantia nigra to other brain regions. |
1981-01-16 |
2023-08-12 |
Not clear |
| D B Calne, J K Kebabia. Parkinson's disease: unanswered questions. Journal of neural transmission. Supplementum. issue 16. 1981-01-16. PMID:6933216. |
the role of the depletion of dopamine in parkinsonism is also unclear; we do not even know whether the impact of the deficit is more significant in the basal ganglia, or the substantia nigra. |
1981-01-16 |
2023-08-12 |
Not clear |
| L A Chiodo, A R Caggiul. Alterations in basal firing rate and autoreceptor sensitivity of dopamine neurons in the substantia nigra following acute and extended exposure to estrogen. European journal of pharmacology. vol 67. issue 1. 1980-12-18. PMID:7418731. |
alterations in basal firing rate and autoreceptor sensitivity of dopamine neurons in the substantia nigra following acute and extended exposure to estrogen. |
1980-12-18 |
2023-08-12 |
Not clear |
| A Björklund, S B Dunnett, U Stenevi, M E Lewis, S D Iverse. Reinnervation of the denervated striatum by substantia nigra transplants: functional consequences as revealed by pharmacological and sensorimotor testing. Brain research. vol 199. issue 2. 1980-12-16. PMID:7417786. |
embryonic substantia nigra (sn) was transplanted to the neostriatum in adult rats subjected to a unilateral or serial bilateral destruction of the nigrostriatal dopamine (da) pathway. |
1980-12-16 |
2023-08-12 |
rat |
| T H Svensson, G Engber. Antagonism of ethanol's central stimulation by catecholamine receptor agonists. Advances in experimental medicine and biology. vol 126. 1980-10-27. PMID:6773308. |
identified dopamine (da) neurons of the zona compacta, substantia nigra as well as noradrenaline (na) neurons of the locus coeruleus showed no alterations in firing rate at ethanol administration. |
1980-10-27 |
2023-08-12 |
rat |
| L J Roger, G R Breese, P Morel. Axonal transport of proteins and glycoproteins in the rat nigro-striatal pathway and the effects of 6-hydroxydopamine. Brain research. vol 197. issue 1. 1980-10-24. PMID:6156743. |
in control experiments, [3h]dopa wa injected into the substantia nigra, and [3h]dopamine was measured in corpus striatum; 6-ohda treatment reduced the amounts of striatal [3h]dopamine recovered to 3% of control values. |
1980-10-24 |
2023-08-12 |
rat |
| N M Nicolao. Acute and chronic effects of neuroleptics and acute effects of apomorphine and amphetamine on dopamine turnover in corpus striatum and substantia nigra of the rat brain. European journal of pharmacology. vol 64. issue 2-3. 1980-10-21. PMID:6105080. |
acute and chronic effects of neuroleptics and acute effects of apomorphine and amphetamine on dopamine turnover in corpus striatum and substantia nigra of the rat brain. |
1980-10-21 |
2023-08-12 |
rat |