| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I C Kilpatrick, M S Star. Involvement of dopamine in circling responses to muscimol depends on intranigral site of injection. European journal of pharmacology. vol 69. issue 4. 1981-09-25. PMID:6265225. |
the intensity, direction and dopamine dependence of circling behaviour were determined following stereotaxic injections of 40 ng muscimol (in 0.2 microliter over 3 min) into different regions of the rat's substantia nigra (sn). |
1981-09-25 |
2023-08-12 |
rat |
| P G Guyenet, J K Cran. Non-dopaminergic nigrostriatal pathway. Brain research. vol 213. issue 2. 1981-09-15. PMID:7248760. |
(1) in 3 control rats injected with 0.1 microliter of a 10% solution of eb in the center of the caudate-putamen 1 mm anterior to the globus pallidus, 96% of all substantia nigra neurons retrogradely labelled with the dye contained dopamine fluorescence. |
1981-09-15 |
2023-08-12 |
rat |
| P G Guyenet, J K Cran. Non-dopaminergic nigrostriatal pathway. Brain research. vol 213. issue 2. 1981-09-15. PMID:7248760. |
the remaining ones (average 350 per brain) were devoid of dopamine fluorescence and predominantly found in the posterior 75% of the substantia nigra. |
1981-09-15 |
2023-08-12 |
rat |
| P G Guyenet, J K Cran. Non-dopaminergic nigrostriatal pathway. Brain research. vol 213. issue 2. 1981-09-15. PMID:7248760. |
despite a reduction of up to 85% in the number of dopaminergic cell bodies, the substantia nigra of these rats contained the same average number of eb-labelled neurons devoid of dopamine fluorescence. |
1981-09-15 |
2023-08-12 |
rat |
| K Gal. Relationship between the presence of dopaminergic neurons and GABA receptors in substantia nigra: effects of lesions. Brain research. vol 210. issue 1-2. 1981-07-23. PMID:6112044. |
in rats with lesions which caused maximal destruction of nigrostriatal dopamine neurons (striatal tyrosine hydroxylase was less than 15% of control), specific gaba binding in substantia nigra was apparently not different from that obtained in intact controls. |
1981-07-23 |
2023-08-12 |
rat |
| A Ruffieux, W Schult. [Influence of dopamine on pars reticulata neurones of substantia nigra (author's transl)]. Journal de physiologie. vol 77. issue 1. 1981-07-09. PMID:7230051. |
[influence of dopamine on pars reticulata neurones of substantia nigra (author's transl)]. |
1981-07-09 |
2023-08-12 |
rat |
| A Ruffieux, W Schult. [Influence of dopamine on pars reticulata neurones of substantia nigra (author's transl)]. Journal de physiologie. vol 77. issue 1. 1981-07-09. PMID:7230051. |
1 dendrites of the dopamine neurones of pars compacta extend into pars reticulata of substantia nigra. |
1981-07-09 |
2023-08-12 |
rat |
| A Ruffieux, W Schult. [Influence of dopamine on pars reticulata neurones of substantia nigra (author's transl)]. Journal de physiologie. vol 77. issue 1. 1981-07-09. PMID:7230051. |
2 in order to test this hypothesis, we have studied the effects of iontophoretically applied dopamine on pars reticulata neurones of substantia nigra in rats under chloralhydrate and under urethane anaesthesia. |
1981-07-09 |
2023-08-12 |
rat |
| M Casu, K Gal. Differential effects of gamma-aminobutyric acid (GABA)-elevating agents on the neuroleptic-induced activation of striatal tyrosine-hydroxylase: evidence that di-n-propylacetate augments GABAergic neurotransmission. The Journal of pharmacology and experimental therapeutics. vol 217. issue 1. 1981-05-26. PMID:6110774. |
in order to determine whether the dpa-induced increase in nerve-terminal gaba could augment gabaergic transmission in substantia nigra, we examined the ability of dpa to influence nigrostriatal dopamine function. |
1981-05-26 |
2023-08-12 |
Not clear |
| F Hefti, E Melamed, R J Wurtma. The site of dopamine formation in rat striatum after L-dopa administration. The Journal of pharmacology and experimental therapeutics. vol 217. issue 1. 1981-05-26. PMID:7205652. |
unilateral nigrostriatal lesions produced by injecting 6-hydroxydopamine stereotaxically into both the substantia nigra and the medial forebrain bundle reduced striatal tyrosine hydroxylase activity and dopamine (da) concentrations by 95% (compared with the intact, contralateral striata) but lowered dopa decarboxylase (ddc) activity by only 80%. |
1981-05-26 |
2023-08-12 |
rat |
| S Browder, D C German, P A Shor. Midbrain dopamine neurons: differential responses to amphetamine isomers. Brain research. vol 207. issue 2. 1981-05-26. PMID:7470912. |
intravenously administered d- and l-amphetamine have different potency ratios in reducing the firing rates of dopamine cells in the substantia nigra and in the ventral tegmental area. |
1981-05-26 |
2023-08-12 |
Not clear |
| S Browder, D C German, P A Shor. Midbrain dopamine neurons: differential responses to amphetamine isomers. Brain research. vol 207. issue 2. 1981-05-26. PMID:7470912. |
while d-amphetamine is considerably more potent than l-amphetamine in reducing ventral substantia nigra dopamine neuronal impulse flow, d- and l-amphetamine are of similar potency in reducing dorsal substantia nigra and ventral tegmental dopamine neuronal impulse flow. |
1981-05-26 |
2023-08-12 |
Not clear |
| S Browder, D C German, P A Shor. Midbrain dopamine neurons: differential responses to amphetamine isomers. Brain research. vol 207. issue 2. 1981-05-26. PMID:7470912. |
the comparable potencies of the d- and l-isomers on dorsal substantia nigra and ventral tegmental area dopamine neurons may explain, by a dopamine mechanism, the finding that comparable doses of the isomers produce schizophrenic-like symptoms. |
1981-05-26 |
2023-08-12 |
Not clear |
| F Fadda, A Argiolas, M R Melis, G Serr. Effect of acute and chronic ethanol on dopamine synthesis in the caudate nucleus, substantia nigra and frontal cortex. Bollettino della Societa italiana di biologia sperimentale. vol 56. issue 24. 1981-05-21. PMID:7470302. |
effect of acute and chronic ethanol on dopamine synthesis in the caudate nucleus, substantia nigra and frontal cortex. |
1981-05-21 |
2023-08-12 |
rat |
| F Fadda, A Argiolas, M R Melis, G Serr. Effect of acute and chronic ethanol on dopamine synthesis in the caudate nucleus, substantia nigra and frontal cortex. Bollettino della Societa italiana di biologia sperimentale. vol 56. issue 24. 1981-05-21. PMID:7470302. |
a single oral administration of 3.2 g/kg ethanol to normal rats increased 3,4-dihydroxyphenylacetic acid (dopac) content and dopa formation in the caudate nucleus but had no effect in frontal cortex and substantia nigra and did not modify dopamine (da) levels in any of the brain regions analyzed. |
1981-05-21 |
2023-08-12 |
rat |
| F Fadda, A Argiolas, M R Melis, G Serra, S Congi. Effect of ethanol on the metabolism of regional brain dopamine. Bollettino della Societa italiana di biologia sperimentale. vol 56. issue 24. 1981-05-21. PMID:7470303. |
acute oral administration of ethanol (3.2g/kg) to rats increased (dopac) levels in the caudate nucleus, but had no effect on dopac levels in the substantia nigra and frontal cortex and failed to modify dopamine content in any of the above areas. |
1981-05-21 |
2023-08-12 |
rat |
| A Kuruvilla, N J Uretsk. Effect of sodium valproate on motor function regulated by the activation of GABA receptors. Psychopharmacology. vol 72. issue 2. 1981-05-13. PMID:6259678. |
gaba interacts with dopamine functionally in certain areas of the brain involved in motor behavior such as the nucleus accumbens and the substantia nigra. |
1981-05-13 |
2023-08-12 |
rat |
| A Cheramy, V Leviel, J Glowinsk. Dendritic release of dopamine in the substantia nigra. Nature. vol 289. issue 5798. 1981-04-13. PMID:6258083. |
dendritic release of dopamine in the substantia nigra. |
1981-04-13 |
2023-08-12 |
Not clear |
| A Cheramy, V Leviel, J Glowinsk. Dendritic release of dopamine in the substantia nigra. Nature. vol 289. issue 5798. 1981-04-13. PMID:6258083. |
dopamine can be released in the substantia nigra for the dendrites of nigrostriatal dopaminergic neurones, to be involved there in the self-regulation of the dopaminergic cells, to control the release of neurotransmitters from nigral afferent fibres and to influence the activity of nigral non-dopaminergic cells. |
1981-04-13 |
2023-08-12 |
Not clear |
| O Hornykiewic. [Brain dopamine and brain disorders - and what we have learned from these studies (author's transl)]. Wiener klinische Wochenschrift. vol 92. issue 20. 1981-04-13. PMID:7467350. |
two examples are given to illustrate the role of dopamine in brain disorders: a) in parkinson's disease there is a marked deficiency of dopamine in several subcortical brain regions, particularly the striatum (caudate nucleus and putamen) and substantia nigra. |
1981-04-13 |
2023-08-12 |
Not clear |