| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Hökfelt, B J Everitt, E Theodorsson-Norheim, M Goldstei. Occurrence of neurotensinlike immunoreactivity in subpopulations of hypothalamic, mesencephalic, and medullary catecholamine neurons. The Journal of comparative neurology. vol 222. issue 4. 1984-04-26. PMID:6365985. |
in the ventral mesencephalon, neurotensinlike immunoreactivity was seen mainly in dopamine cell bodies in the ventral tegmental area, including midline structures, with only single examples of coexistence in the substantia nigra. |
1984-04-26 |
2023-08-12 |
rat |
| C Mytilineou, G Cohen, D Dembiec-Cohen, M Van Woert, E Hwan. Explant cultures of dog substantia nigra and striatum: a model for the study of nigro-striatal dopamine neurons. Journal of neural transmission. Supplementum. vol 19. 1984-04-04. PMID:6321649. |
explant cultures of dog substantia nigra and striatum: a model for the study of nigro-striatal dopamine neurons. |
1984-04-04 |
2023-08-12 |
dog |
| H Watanabe, S Hata, K Watanab. [Pharmacological investigation of rotational behaviors produced by unilateral electrical stimulation of the substantia nigra in the rat]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 82. issue 4. 1984-03-23. PMID:6141127. |
unilateral electrical stimulation of the substantia nigra produced an increase in the content of dopamine metabolites in the ipsilateral striatum of the rat pretreated with probenecid. |
1984-03-23 |
2023-08-12 |
rat |
| E L Gardner, T F Seege. Neurobehavioral evidence for mesolimbic specificity of action by clozapine: studies using electrical intracranial self-stimulation. Biological psychiatry. vol 18. issue 12. 1984-03-23. PMID:6661466. |
in contrast, animals with electrodes in the substantia nigra (nigrostriatal dopamine cell body area) showed no change in self-stimulation rate following 3 weeks of chronic clozapine. |
1984-03-23 |
2023-08-12 |
rat |
| K Koshiya, T Kat. Acute changes in nigral substance P content induced by drugs acting on dopamine, muscarine and GABA receptors. Naunyn-Schmiedeberg's archives of pharmacology. vol 324. issue 3. 1984-02-24. PMID:6197660. |
effects of acutely administered drugs acting on dopamine, muscarine or gaba receptors on the substance p content in rat substantia nigra were examined. |
1984-02-24 |
2023-08-12 |
rat |
| J Williams, J A Davie. The involvement of 5-hydroxytryptamine in the release of dendritic dopamine from slices of rat substantia nigra. The Journal of pharmacy and pharmacology. vol 35. issue 11. 1984-01-27. PMID:6139455. |
the involvement of 5-hydroxytryptamine in the release of dendritic dopamine from slices of rat substantia nigra. |
1984-01-27 |
2023-08-12 |
rat |
| J Williams, J A Davie. The involvement of 5-hydroxytryptamine in the release of dendritic dopamine from slices of rat substantia nigra. The Journal of pharmacy and pharmacology. vol 35. issue 11. 1984-01-27. PMID:6139455. |
[3h]dopamine (da) accumulated by slices of rat substantia nigra was released following superfusion with krebs solution containing 5-hydroxytryptamine (5-ht) in a dose-dependent fashion with maximal release being produced by 1 x 10(-4) m. this 5-ht-induced release of [3h]da was calcium-dependent and was inhibited by pretreatment with the 5-ht antagonist cinanserin. |
1984-01-27 |
2023-08-12 |
rat |
| A Altar, K A Neve, S E Loughlin, J F Marshall, J H Fallo. The crossed mesostriatal projection: neurochemistry and developmental response to lesion. Brain research. vol 279. issue 1-2. 1984-01-27. PMID:6416611. |
the projections of substantia nigra and ventral tegmental area (sn-vta) neurons to either the ipsilateral or contralateral caudate-putamen (cp) were studied in intact and 6-hydroxydopamine-treated rats, using both retrograde transport of fluorescent dyes and measurements of dopamine concentration. |
1984-01-27 |
2023-08-12 |
rat |
| A J Bradbury, B Costall, R J Naylo. Reduction in motor responding of the mouse by actions of dopamine agonists in the midbrain. Neuropharmacology. vol 22. issue 10. 1984-01-27. PMID:6646352. |
mice were implanted stereotaxically with chronically indwelling bilateral guide cannulae to allow the intracerebral injection of dopamine or the dopamine agonist 2-di-n-propylamino-5,6-dihydroxytetralin into the centre of the substantia nigra, above the substantia nigra or anterior and posterior to the nigra. |
1984-01-27 |
2023-08-12 |
mouse |
| A J Bradbury, B Costall, R J Naylo. Reduction in motor responding of the mouse by actions of dopamine agonists in the midbrain. Neuropharmacology. vol 22. issue 10. 1984-01-27. PMID:6646352. |
the effectiveness of dopamine decreased with a delayed onset when injections were made anterior or posterior to the substantia nigra; this spectrum of reduced and delayed responding was also apparent when dopamine and the tetralin compound were injected 1 or 2 mm above the nigra. |
1984-01-27 |
2023-08-12 |
mouse |
| A J Bradbury, B Costall, R J Naylo. Reduction in motor responding of the mouse by actions of dopamine agonists in the midbrain. Neuropharmacology. vol 22. issue 10. 1984-01-27. PMID:6646352. |
the inhibitory action of dopamine on motor activity, when injected into the substantia nigra, was antagonised by a small dose of spiroperidol which did not influence spontaneous locomotor responding in its own right; prazosin and yohimbine were ineffective. |
1984-01-27 |
2023-08-12 |
mouse |
| D Dewar, P Jenner, C D Marsde. Lesions of the globus pallidus, entopeduncular nucleus and substantia nigra alter dopamine mediated circling behaviour. Experimental brain research. vol 52. issue 2. 1984-01-07. PMID:6641888. |
lesions of the globus pallidus, entopeduncular nucleus and substantia nigra alter dopamine mediated circling behaviour. |
1984-01-07 |
2023-08-12 |
rat |
| L A Chiodo, B S Bunne. Electrophysiological studies on EMD 23 448, an indolyl-3-butylamine, in the rat: a putative selective dopamine autoreceptor agonist. Neuropharmacology. vol 22. issue 9. 1983-12-21. PMID:6138728. |
single unit electrophysiological and microiontophoretic techniques were used to study the effects of a putative selective dopamine autoreceptor agonist, emd 23 448, an indolyl-3-butylamine on the activity of both dopamine neurons in the substantia nigra and dopamine-sensitive neurons in the caudate nucleus. |
1983-12-21 |
2023-08-12 |
rat |
| R D Huffman, M K Tick. The effects of chronic haloperidol administration on GABA receptor binding. Pharmacology, biochemistry, and behavior. vol 19. issue 2. 1983-12-20. PMID:6314387. |
these observations suggest that blockade of dopamine receptors in the striatum by haloperidol results in a compensatory decrease in the activity of the gabaergic strionigral system that leads to an increase in the number of gaba binding sites within the substantia nigra. |
1983-12-20 |
2023-08-12 |
rat |
| G Gianutsos, G M Carlson, J G Godfre. Drug-induced changes in motor activity after selective MAO inhibition. Pharmacology, biochemistry, and behavior. vol 19. issue 2. 1983-12-20. PMID:6634874. |
the clorgyline pretreatment resulted in larger increases in brain dopamine concentrations (in the striatum, olfactory tubercles and in the area containing the substantia nigra) than did mao-b inhibition. |
1983-12-20 |
2023-08-12 |
mouse |
| J D Miller, J Farber, P Gatz, H Roffwarg, D C Germa. Activity of mesencephalic dopamine and non-dopamine neurons across stages of sleep and walking in the rat. Brain research. vol 273. issue 1. 1983-11-23. PMID:6616218. |
single unit activity of dopamine and non-dopamine neurons in the substantia nigra and ventral tegmental area was recorded across stages of sleep and waking in the rat. |
1983-11-23 |
2023-08-12 |
rat |
| P Piccardi, F Bernardi, Z Rossetti, G Corsin. Effect of estrogens on dopamine autoreceptors in male rats. European journal of pharmacology. vol 91. issue 1. 1983-11-23. PMID:6617733. |
recent electrophysiological data, showing that estrogens significantly attenuate the ability of apomorphine to inhibit the firing activity of type b dopamine neurons in the rat substantia nigra, suggest that these hormones may also induce subsensitivity of da autoreceptors. |
1983-11-23 |
2023-08-12 |
rat |
| N E Andén, M Grabowska-Andén, S Lindgren, U Thornströ. Synthesis rate of dopamine: difference between corpus striatum and limbic system as a possible explanation of variations in reactions to drugs. Naunyn-Schmiedeberg's archives of pharmacology. vol 323. issue 3. 1983-11-23. PMID:6621714. |
the lower dopamine synthesis rate in the latter region may be due to a negative neuronal feedback from the corpus striatum to the substantia nigra. |
1983-11-23 |
2023-08-12 |
rat |
| F J White, R Y Wan. Differential effects of classical and atypical antipsychotic drugs on A9 and A10 dopamine neurons. Science (New York, N.Y.). vol 221. issue 4615. 1983-09-23. PMID:6136093. |
prolonged treatment with classical antipsychotic drugs decreased the number of spontaneously active dopamine neurons in both the substantia nigra (a9) and the ventral tegmental area (a10) of the rat brain. |
1983-09-23 |
2023-08-12 |
rat |
| W J Freed, F Karoum, H E Spoor, J M Morihisa, L Olson, R J Wyat. Catecholamine content of intracerebral adrenal medulla grafts. Brain research. vol 269. issue 1. 1983-09-23. PMID:6683581. |
in hosts with substantia nigra lesions, concentrations of dopamine in the adrenal medulla grafts were decreased. |
1983-09-23 |
2023-08-12 |
Not clear |