| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B K Yamamoto, C R Free. Asymmetric dopamine and serotonin metabolism in nigrostriatal and limbic structures of the trained circling rat. Brain research. vol 297. issue 1. 1984-07-09. PMID:6202362. |
we have now studied changes in dopamine and serotonin turnover in nucleus accumbens, substantia nigra and amygdala. |
1984-07-09 |
2023-08-12 |
rat |
| B K Yamamoto, C R Free. Asymmetric dopamine and serotonin metabolism in nigrostriatal and limbic structures of the trained circling rat. Brain research. vol 297. issue 1. 1984-07-09. PMID:6202362. |
by contrast, dopamine turnover in substantia nigra exhibited a relative decline on the contralateral side. |
1984-07-09 |
2023-08-12 |
rat |
| R D Pinnoc. Sensitivity of compacta neurones in the rat substantia nigra slice to dopamine agonists. European journal of pharmacology. vol 96. issue 3-4. 1984-07-09. PMID:6676108. |
sensitivity of compacta neurones in the rat substantia nigra slice to dopamine agonists. |
1984-07-09 |
2023-08-12 |
rat |
| A Barbea. Manganese and extrapyramidal disorders (a critical review and tribute to Dr. George C. Cotzias). Neurotoxicology. vol 5. issue 1. 1984-06-20. PMID:6538948. |
thirdly the author proposes that the necessary event to the so-called "depigmentation" of the substantia nigra and subsequent bradykinetic "low dopamine" syndrome is an early enhanced turnover of dopamine. |
1984-06-20 |
2023-08-12 |
Not clear |
| A Barbea. Manganese and extrapyramidal disorders (a critical review and tribute to Dr. George C. Cotzias). Neurotoxicology. vol 5. issue 1. 1984-06-20. PMID:6538948. |
in turn, this increased synthesis of dopamine favours the production of large quantities of free radicals within the cell bodies in the substantia nigra, eventually overflowing the scavenging capacity of neuromelanin and their protective barrier, and causing cell death. |
1984-06-20 |
2023-08-12 |
Not clear |
| G Toffano, G E Savoini, F Moroni, G Lombardi, L Calzà, L F Agnat. Chronic GM1 ganglioside treatment reduces dopamine cell body degeneration in the substantia nigra after unilateral hemitransection in rat. Brain research. vol 296. issue 2. 1984-05-21. PMID:6142756. |
chronic gm1 ganglioside treatment reduces dopamine cell body degeneration in the substantia nigra after unilateral hemitransection in rat. |
1984-05-21 |
2023-08-12 |
rat |
| R D Myers, T F Le. In vivo release of dopamine during perfusion of neurotensin in substantia nigra of the unrestrained rat. Peptides. vol 4. issue 6. 1984-05-11. PMID:6672795. |
in vivo release of dopamine during perfusion of neurotensin in substantia nigra of the unrestrained rat. |
1984-05-11 |
2023-08-12 |
rat |
| R D Myers, T F Le. In vivo release of dopamine during perfusion of neurotensin in substantia nigra of the unrestrained rat. Peptides. vol 4. issue 6. 1984-05-11. PMID:6672795. |
the functional effect of neurotensin on the kinetics of dopamine (da) release in the substantia nigra of the freely moving rat was investigated. |
1984-05-11 |
2023-08-12 |
rat |
| T Hökfelt, B J Everitt, E Theodorsson-Norheim, M Goldstei. Occurrence of neurotensinlike immunoreactivity in subpopulations of hypothalamic, mesencephalic, and medullary catecholamine neurons. The Journal of comparative neurology. vol 222. issue 4. 1984-04-26. PMID:6365985. |
in the ventral mesencephalon, neurotensinlike immunoreactivity was seen mainly in dopamine cell bodies in the ventral tegmental area, including midline structures, with only single examples of coexistence in the substantia nigra. |
1984-04-26 |
2023-08-12 |
rat |
| C Mytilineou, G Cohen, D Dembiec-Cohen, M Van Woert, E Hwan. Explant cultures of dog substantia nigra and striatum: a model for the study of nigro-striatal dopamine neurons. Journal of neural transmission. Supplementum. vol 19. 1984-04-04. PMID:6321649. |
explant cultures of dog substantia nigra and striatum: a model for the study of nigro-striatal dopamine neurons. |
1984-04-04 |
2023-08-12 |
dog |
| H Watanabe, S Hata, K Watanab. [Pharmacological investigation of rotational behaviors produced by unilateral electrical stimulation of the substantia nigra in the rat]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 82. issue 4. 1984-03-23. PMID:6141127. |
unilateral electrical stimulation of the substantia nigra produced an increase in the content of dopamine metabolites in the ipsilateral striatum of the rat pretreated with probenecid. |
1984-03-23 |
2023-08-12 |
rat |
| E L Gardner, T F Seege. Neurobehavioral evidence for mesolimbic specificity of action by clozapine: studies using electrical intracranial self-stimulation. Biological psychiatry. vol 18. issue 12. 1984-03-23. PMID:6661466. |
in contrast, animals with electrodes in the substantia nigra (nigrostriatal dopamine cell body area) showed no change in self-stimulation rate following 3 weeks of chronic clozapine. |
1984-03-23 |
2023-08-12 |
rat |
| K Koshiya, T Kat. Acute changes in nigral substance P content induced by drugs acting on dopamine, muscarine and GABA receptors. Naunyn-Schmiedeberg's archives of pharmacology. vol 324. issue 3. 1984-02-24. PMID:6197660. |
effects of acutely administered drugs acting on dopamine, muscarine or gaba receptors on the substance p content in rat substantia nigra were examined. |
1984-02-24 |
2023-08-12 |
rat |
| J Williams, J A Davie. The involvement of 5-hydroxytryptamine in the release of dendritic dopamine from slices of rat substantia nigra. The Journal of pharmacy and pharmacology. vol 35. issue 11. 1984-01-27. PMID:6139455. |
the involvement of 5-hydroxytryptamine in the release of dendritic dopamine from slices of rat substantia nigra. |
1984-01-27 |
2023-08-12 |
rat |
| J Williams, J A Davie. The involvement of 5-hydroxytryptamine in the release of dendritic dopamine from slices of rat substantia nigra. The Journal of pharmacy and pharmacology. vol 35. issue 11. 1984-01-27. PMID:6139455. |
[3h]dopamine (da) accumulated by slices of rat substantia nigra was released following superfusion with krebs solution containing 5-hydroxytryptamine (5-ht) in a dose-dependent fashion with maximal release being produced by 1 x 10(-4) m. this 5-ht-induced release of [3h]da was calcium-dependent and was inhibited by pretreatment with the 5-ht antagonist cinanserin. |
1984-01-27 |
2023-08-12 |
rat |
| A Altar, K A Neve, S E Loughlin, J F Marshall, J H Fallo. The crossed mesostriatal projection: neurochemistry and developmental response to lesion. Brain research. vol 279. issue 1-2. 1984-01-27. PMID:6416611. |
the projections of substantia nigra and ventral tegmental area (sn-vta) neurons to either the ipsilateral or contralateral caudate-putamen (cp) were studied in intact and 6-hydroxydopamine-treated rats, using both retrograde transport of fluorescent dyes and measurements of dopamine concentration. |
1984-01-27 |
2023-08-12 |
rat |
| A J Bradbury, B Costall, R J Naylo. Reduction in motor responding of the mouse by actions of dopamine agonists in the midbrain. Neuropharmacology. vol 22. issue 10. 1984-01-27. PMID:6646352. |
mice were implanted stereotaxically with chronically indwelling bilateral guide cannulae to allow the intracerebral injection of dopamine or the dopamine agonist 2-di-n-propylamino-5,6-dihydroxytetralin into the centre of the substantia nigra, above the substantia nigra or anterior and posterior to the nigra. |
1984-01-27 |
2023-08-12 |
mouse |
| A J Bradbury, B Costall, R J Naylo. Reduction in motor responding of the mouse by actions of dopamine agonists in the midbrain. Neuropharmacology. vol 22. issue 10. 1984-01-27. PMID:6646352. |
the effectiveness of dopamine decreased with a delayed onset when injections were made anterior or posterior to the substantia nigra; this spectrum of reduced and delayed responding was also apparent when dopamine and the tetralin compound were injected 1 or 2 mm above the nigra. |
1984-01-27 |
2023-08-12 |
mouse |
| A J Bradbury, B Costall, R J Naylo. Reduction in motor responding of the mouse by actions of dopamine agonists in the midbrain. Neuropharmacology. vol 22. issue 10. 1984-01-27. PMID:6646352. |
the inhibitory action of dopamine on motor activity, when injected into the substantia nigra, was antagonised by a small dose of spiroperidol which did not influence spontaneous locomotor responding in its own right; prazosin and yohimbine were ineffective. |
1984-01-27 |
2023-08-12 |
mouse |
| D Dewar, P Jenner, C D Marsde. Lesions of the globus pallidus, entopeduncular nucleus and substantia nigra alter dopamine mediated circling behaviour. Experimental brain research. vol 52. issue 2. 1984-01-07. PMID:6641888. |
lesions of the globus pallidus, entopeduncular nucleus and substantia nigra alter dopamine mediated circling behaviour. |
1984-01-07 |
2023-08-12 |
rat |