| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J G Wood, A Westmoreland, K Bes. Intraneuronal dopamine in the primate substantia nigra. Acta histochemica. Supplementband. vol 36. 1989-07-07. PMID:3150568. |
intraneuronal dopamine in the primate substantia nigra. |
1989-07-07 |
2023-08-11 |
Not clear |
| J G Wood, A Westmoreland, K Bes. Intraneuronal dopamine in the primate substantia nigra. Acta histochemica. Supplementband. vol 36. 1989-07-07. PMID:3150568. |
the substantia nigra (sn) area compacta (ac) of primates was studied at various microscopic levels following treatment for the histo/cytochemical localization of dopamine (da) in an effort to establish the intraneuronal loci of da in neuron cell bodies. |
1989-07-07 |
2023-08-11 |
Not clear |
| K W Lang. [Significance of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine for the etiology and therapy of idiopathic Parkinson disease]. Fortschritte der Neurologie-Psychiatrie. vol 57. issue 4. 1989-07-05. PMID:2656447. |
exposure of drug addicts to mptp (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) has caused a parkinsonian syndrome accompanied by a selective destruction of dopamine containing neurones in the pars compacta of the substantia nigra. |
1989-07-05 |
2023-08-11 |
human |
| D T Dexter, F R Wells, A J Lees, F Agid, Y Agid, P Jenner, C D Marsde. Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease. Journal of neurochemistry. vol 52. issue 6. 1989-06-23. PMID:2723638. |
increased levels of total iron in the substantia nigra may cause the excessive formation of toxic oxygen radicals, leading to dopamine cell death. |
1989-06-23 |
2023-08-11 |
Not clear |
| E P Lapin, H S Maker, H Sershen, A Lajth. Action of nicotine on accumbens dopamine and attenuation with repeated administration. European journal of pharmacology. vol 160. issue 1. 1989-06-20. PMID:2714363. |
dopamine, dopac, hva, 3-methoxytyramine, norepinephrine, 5-hydroxytyramine, and 5-hiaa were measured in the frontal cortex, olfactory tubercle, nucleus accumbens, caudate-putamen, substantia nigra and ventral tegmental area. |
1989-06-20 |
2023-08-11 |
rat |
| M Hadjiconstantinou, A P Mariani, N H Nef. GM1 ganglioside-induced recovery of nigrostriatal dopaminergic neurons after MPTP: an immunohistochemical study. Brain research. vol 484. issue 1-2. 1989-06-15. PMID:2565752. |
the administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) to mice results in the loss of dopamine (da) and 3,4-dihydroxyphenylacetic acid (dopac) from the mouse striatum and a loss of cells containing tyrosine hydroxylase (th)-immunoreactivity from the substantia nigra. |
1989-06-15 |
2023-08-11 |
mouse |
| R Meloni, J Childs, F Gerogan, S Yurkofsky, K Gal. Effect of haloperidol on transplants of fetal substantia nigra: evidence for feedback regulation of dopamine turnover in the graft and its projections. Progress in brain research. vol 78. 1989-06-15. PMID:2854639. |
effect of haloperidol on transplants of fetal substantia nigra: evidence for feedback regulation of dopamine turnover in the graft and its projections. |
1989-06-15 |
2023-08-11 |
Not clear |
| G Fishell, D van der Koo. Pattern formation in the striatum: developmental changes in the distribution of striatonigral projections. Brain research. Developmental brain research. vol 45. issue 2. 1989-06-09. PMID:2713982. |
in all experimental cases the anterogradely labeled sections of the substantia nigra were also stained with antibodies to tyrosine hydroxylase, which permitted differentiation of the dopamine cell rich pars compacta from the dopamine cell poor pars reticulata. |
1989-06-09 |
2023-08-11 |
Not clear |
| S I Walaas, G Sedvall, P Greengar. Dopamine-regulated phosphorylation of synaptic vesicle-associated proteins in rat neostriatum and substantia nigra. Neuroscience. vol 29. issue 1. 1989-06-08. PMID:2496331. |
dopamine, acting through dopamine d1 receptors and cyclic amp-dependent protein kinase, has been found to increase the state of phosphorylation of the synaptic vesicle-associated phosphoproteins synapsin i and protein iii in slices of rat neostriatum and substantia nigra. |
1989-06-08 |
2023-08-11 |
rat |
| S I Walaas, G Sedvall, P Greengar. Dopamine-regulated phosphorylation of synaptic vesicle-associated proteins in rat neostriatum and substantia nigra. Neuroscience. vol 29. issue 1. 1989-06-08. PMID:2496331. |
in the substantia nigra, the effect of dopamine also appeared to be mediated through a d1 dopamine receptor, since it was abolished by fluphenazine and sch 23390. |
1989-06-08 |
2023-08-11 |
rat |
| S I Walaas, G Sedvall, P Greengar. Dopamine-regulated phosphorylation of synaptic vesicle-associated proteins in rat neostriatum and substantia nigra. Neuroscience. vol 29. issue 1. 1989-06-08. PMID:2496331. |
the maximal effect of dopamine in the substantia nigra represented approximately two-thirds of the effect induced by 8-bromo cyclic amp, suggesting that a similar fraction of nerve terminals in the substantia nigra may express the dopamine d1 receptor. |
1989-06-08 |
2023-08-11 |
rat |
| S I Walaas, G Sedvall, P Greengar. Dopamine-regulated phosphorylation of synaptic vesicle-associated proteins in rat neostriatum and substantia nigra. Neuroscience. vol 29. issue 1. 1989-06-08. PMID:2496331. |
the ability of dopamine d1 receptor activation to stimulate both synapsin i and protein iii phosphorylation and gaba release in both the neostriatum and substantia nigra may be causally linked. |
1989-06-08 |
2023-08-11 |
rat |
| T H Lee, E H Ellinwoo. Time-dependent changes in the sensitivity of dopamine neurons to low doses of apomorphine following amphetamine infusion. Brain research. vol 483. issue 1. 1989-06-06. PMID:2495842. |
in contrast to no changes in the spontaneous firing rate of single dopamine cells, the potency of apomorphine in the substantia nigra was markedly decreased soon after withdrawal, followed by an increase 7 days later. |
1989-06-06 |
2023-08-11 |
rat |
| H Akaoka, P A Vitte, P Lestage, C F Saunier, P Bobillier, G Chouve. Apomorphine-induced inhibition of substantia nigra dopamine neurons: effects of unilateral injection through the internal carotid artery. Neuroscience letters. vol 98. issue 2. 1989-06-06. PMID:2710414. |
apomorphine-induced inhibition of substantia nigra dopamine neurons: effects of unilateral injection through the internal carotid artery. |
1989-06-06 |
2023-08-11 |
Not clear |
| N Lindefors, E Brodin, U Tossman, J Segovia, U Ungersted. Tissue levels and in vivo release of tachykinins and GABA in striatum and substantia nigra of rat brain after unilateral striatal dopamine denervation. Experimental brain research. vol 74. issue 3. 1989-06-01. PMID:2468514. |
tissue levels and in vivo release of tachykinins and gaba in striatum and substantia nigra of rat brain after unilateral striatal dopamine denervation. |
1989-06-01 |
2023-08-11 |
rat |
| N Lindefors, E Brodin, U Tossman, J Segovia, U Ungersted. Tissue levels and in vivo release of tachykinins and GABA in striatum and substantia nigra of rat brain after unilateral striatal dopamine denervation. Experimental brain research. vol 74. issue 3. 1989-06-01. PMID:2468514. |
the dopamine denervation decreased the tissue levels of sp in striatum (-38%) ipsilateral to the lesion and in substantia nigra both ipsi- (-54%) and contralateral (-38%) to the lesion. |
1989-06-01 |
2023-08-11 |
rat |
| N Lindefors, E Brodin, U Tossman, J Segovia, U Ungersted. Tissue levels and in vivo release of tachykinins and GABA in striatum and substantia nigra of rat brain after unilateral striatal dopamine denervation. Experimental brain research. vol 74. issue 3. 1989-06-01. PMID:2468514. |
the basal release of gaba in the striatum was increased with 296% and with 76% during stimulation in the dopamine denervated striatum, while no change in gaba basal or stimulated release was detected in the substantia nigra. |
1989-06-01 |
2023-08-11 |
rat |
| M Diana, M Garcia-Munoz, J Richards, C R Free. Electrophysiological analysis of dopamine cells from the substantia nigra pars compacta of circling rats. Experimental brain research. vol 74. issue 3. 1989-06-01. PMID:2707338. |
these results indicate that the activity of dopamine cells in substantia nigra is increased bilaterally during circling. |
1989-06-01 |
2023-08-11 |
rat |
| R Kapoor, C Webb, S A Greenfiel. Endogenous dopamine modifies electroresponsiveness of pars compacta cells in the guinea pig substantia nigra in vitro. Experimental brain research. vol 74. issue 3. 1989-06-01. PMID:2707341. |
endogenous dopamine modifies electroresponsiveness of pars compacta cells in the guinea pig substantia nigra in vitro. |
1989-06-01 |
2023-08-11 |
Not clear |
| R Kapoor, C Webb, S A Greenfiel. Endogenous dopamine modifies electroresponsiveness of pars compacta cells in the guinea pig substantia nigra in vitro. Experimental brain research. vol 74. issue 3. 1989-06-01. PMID:2707341. |
in the nigrostriatal pathway, dopamine is released not only from striatal nerve terminals, but also locally from the dendrites of nigrostriatal neurones within the substantia nigra itself. |
1989-06-01 |
2023-08-11 |
Not clear |