| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Korfali, W D Knowles, S Uysal, I H Ulus, T Ozme. Fetal substantia nigra grafts. Effect on dopamine receptors in the rat corpus striatium. Cleveland Clinic journal of medicine. vol 56. issue 3. 1989-08-17. PMID:2568188. |
effects of fetal substantia nigra grafts on the dopamine receptors in the corpus striatum in rats were investigated after the destruction of the nigrostriatal dopaminergic pathways with intraventricular 6-hydroxydopamine injections. |
1989-08-17 |
2023-08-11 |
rat |
| J Korf, L D Loopuij. Synaptic and non-synaptic striatal dopamine D2 receptors: possible implications in normal and pathological behaviour. Acta morphologica Neerlando-Scandinavica. vol 26. issue 2-3. 1989-08-16. PMID:2908162. |
the prelimbic cortex and dopamine neurones of the ventral part of the substantia nigra; here the density of d2 receptors are lower. |
1989-08-16 |
2023-08-11 |
Not clear |
| J M Palacios, M Savasta, G Mengo. Does cholecystokinin colocalize with dopamine in the human substantia nigra? Brain research. vol 488. issue 1-2. 1989-08-14. PMID:2743135. |
does cholecystokinin colocalize with dopamine in the human substantia nigra? |
1989-08-14 |
2023-08-11 |
human |
| Y Masuo, I Kanazaw. Effects of the unilateral striatal lesion on neurotransmitter markers in the contralateral striatum and both substantia nigrae of the rat. Neuroscience. vol 27. issue 3. 1989-08-01. PMID:2908058. |
the latter interpretation was supported by the finding that the changes observed were abolished by an additional callosal transection; (2) the second series of changes were transient (only found at 3-7 post-operative days) effects represented by an increase in gaba content, a decrease of tyrosine hydroxylase activity, and a decrease of dopamine content, which mostly appeared in the contralateral substantia nigra. |
1989-08-01 |
2023-08-11 |
rat |
| Y Masuo, I Kanazaw. Effects of the unilateral striatal lesion on neurotransmitter markers in the contralateral striatum and both substantia nigrae of the rat. Neuroscience. vol 27. issue 3. 1989-08-01. PMID:2908058. |
the decrease of dopamine markers may be a subsequent secondary effect of the increase of gaba in the substantia nigra. |
1989-08-01 |
2023-08-11 |
rat |
| M Morelli, T Mennini, G Di Chiar. Nigral dopamine autoreceptors are exclusively of the D2 type: quantitative autoradiography of [125I]iodosulpride and [125I]SCH 23982 in adjacent brain sections. Neuroscience. vol 27. issue 3. 1989-08-01. PMID:2978051. |
the results indicate that dopamine autoreceptors are present in the substantia nigra and in the ventral tegmental area and that they are exclusively of the d2 type. |
1989-08-01 |
2023-08-11 |
rat |
| R M Beckstea. Association of dopamine D1 and D2 receptors with specific cellular elements in the basal ganglia of the cat: the uneven topography of dopamine receptors in the striatum is determined by intrinsic striatal cells, not nigrostriatal axons. Neuroscience. vol 27. issue 3. 1989-08-01. PMID:3150855. |
nearly all d2 receptors in the substantia nigra are associated with dopamine neurons (autoreceptors). |
1989-08-01 |
2023-08-11 |
cat |
| L Ugedo, J Grenhoff, T H Svensso. Ritanserin, a 5-HT2 receptor antagonist, activates midbrain dopamine neurons by blocking serotonergic inhibition. Psychopharmacology. vol 98. issue 1. 1989-07-07. PMID:2524859. |
dopamine cells of the zona compacta, substantia nigra (zc-sn) and the ventral tegmental area (vta) were identified by established criteria. |
1989-07-07 |
2023-08-11 |
rat |
| J G Wood, A Westmoreland, K Bes. Intraneuronal dopamine in the primate substantia nigra. Acta histochemica. Supplementband. vol 36. 1989-07-07. PMID:3150568. |
intraneuronal dopamine in the primate substantia nigra. |
1989-07-07 |
2023-08-11 |
Not clear |
| J G Wood, A Westmoreland, K Bes. Intraneuronal dopamine in the primate substantia nigra. Acta histochemica. Supplementband. vol 36. 1989-07-07. PMID:3150568. |
the substantia nigra (sn) area compacta (ac) of primates was studied at various microscopic levels following treatment for the histo/cytochemical localization of dopamine (da) in an effort to establish the intraneuronal loci of da in neuron cell bodies. |
1989-07-07 |
2023-08-11 |
Not clear |
| K W Lang. [Significance of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine for the etiology and therapy of idiopathic Parkinson disease]. Fortschritte der Neurologie-Psychiatrie. vol 57. issue 4. 1989-07-05. PMID:2656447. |
exposure of drug addicts to mptp (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) has caused a parkinsonian syndrome accompanied by a selective destruction of dopamine containing neurones in the pars compacta of the substantia nigra. |
1989-07-05 |
2023-08-11 |
human |
| D T Dexter, F R Wells, A J Lees, F Agid, Y Agid, P Jenner, C D Marsde. Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease. Journal of neurochemistry. vol 52. issue 6. 1989-06-23. PMID:2723638. |
increased levels of total iron in the substantia nigra may cause the excessive formation of toxic oxygen radicals, leading to dopamine cell death. |
1989-06-23 |
2023-08-11 |
Not clear |
| E P Lapin, H S Maker, H Sershen, A Lajth. Action of nicotine on accumbens dopamine and attenuation with repeated administration. European journal of pharmacology. vol 160. issue 1. 1989-06-20. PMID:2714363. |
dopamine, dopac, hva, 3-methoxytyramine, norepinephrine, 5-hydroxytyramine, and 5-hiaa were measured in the frontal cortex, olfactory tubercle, nucleus accumbens, caudate-putamen, substantia nigra and ventral tegmental area. |
1989-06-20 |
2023-08-11 |
rat |
| M Hadjiconstantinou, A P Mariani, N H Nef. GM1 ganglioside-induced recovery of nigrostriatal dopaminergic neurons after MPTP: an immunohistochemical study. Brain research. vol 484. issue 1-2. 1989-06-15. PMID:2565752. |
the administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) to mice results in the loss of dopamine (da) and 3,4-dihydroxyphenylacetic acid (dopac) from the mouse striatum and a loss of cells containing tyrosine hydroxylase (th)-immunoreactivity from the substantia nigra. |
1989-06-15 |
2023-08-11 |
mouse |
| R Meloni, J Childs, F Gerogan, S Yurkofsky, K Gal. Effect of haloperidol on transplants of fetal substantia nigra: evidence for feedback regulation of dopamine turnover in the graft and its projections. Progress in brain research. vol 78. 1989-06-15. PMID:2854639. |
effect of haloperidol on transplants of fetal substantia nigra: evidence for feedback regulation of dopamine turnover in the graft and its projections. |
1989-06-15 |
2023-08-11 |
Not clear |
| G Fishell, D van der Koo. Pattern formation in the striatum: developmental changes in the distribution of striatonigral projections. Brain research. Developmental brain research. vol 45. issue 2. 1989-06-09. PMID:2713982. |
in all experimental cases the anterogradely labeled sections of the substantia nigra were also stained with antibodies to tyrosine hydroxylase, which permitted differentiation of the dopamine cell rich pars compacta from the dopamine cell poor pars reticulata. |
1989-06-09 |
2023-08-11 |
Not clear |
| S I Walaas, G Sedvall, P Greengar. Dopamine-regulated phosphorylation of synaptic vesicle-associated proteins in rat neostriatum and substantia nigra. Neuroscience. vol 29. issue 1. 1989-06-08. PMID:2496331. |
dopamine, acting through dopamine d1 receptors and cyclic amp-dependent protein kinase, has been found to increase the state of phosphorylation of the synaptic vesicle-associated phosphoproteins synapsin i and protein iii in slices of rat neostriatum and substantia nigra. |
1989-06-08 |
2023-08-11 |
rat |
| S I Walaas, G Sedvall, P Greengar. Dopamine-regulated phosphorylation of synaptic vesicle-associated proteins in rat neostriatum and substantia nigra. Neuroscience. vol 29. issue 1. 1989-06-08. PMID:2496331. |
in the substantia nigra, the effect of dopamine also appeared to be mediated through a d1 dopamine receptor, since it was abolished by fluphenazine and sch 23390. |
1989-06-08 |
2023-08-11 |
rat |
| S I Walaas, G Sedvall, P Greengar. Dopamine-regulated phosphorylation of synaptic vesicle-associated proteins in rat neostriatum and substantia nigra. Neuroscience. vol 29. issue 1. 1989-06-08. PMID:2496331. |
the maximal effect of dopamine in the substantia nigra represented approximately two-thirds of the effect induced by 8-bromo cyclic amp, suggesting that a similar fraction of nerve terminals in the substantia nigra may express the dopamine d1 receptor. |
1989-06-08 |
2023-08-11 |
rat |
| S I Walaas, G Sedvall, P Greengar. Dopamine-regulated phosphorylation of synaptic vesicle-associated proteins in rat neostriatum and substantia nigra. Neuroscience. vol 29. issue 1. 1989-06-08. PMID:2496331. |
the ability of dopamine d1 receptor activation to stimulate both synapsin i and protein iii phosphorylation and gaba release in both the neostriatum and substantia nigra may be causally linked. |
1989-06-08 |
2023-08-11 |
rat |