| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M E Götz, A Freyberger, P Riedere. Oxidative stress: a role in the pathogenesis of Parkinson's disease. Journal of neural transmission. Supplementum. vol 29. 1990-08-01. PMID:2193108. |
the role of melanin in the degenerative process is not clear, but autoxidative reactions such as the oxidation of dopamine (da) to melanin generating radicals and toxic metabolites seem to enhance the vulnerability of neurons in the substantia nigra (sn). |
1990-08-01 |
2023-08-11 |
Not clear |
| R Meloni, K Gal. Pharmacological evidence for feedback regulation of dopamine metabolism in solid fetal substantia nigra transplants. The Journal of pharmacology and experimental therapeutics. vol 253. issue 3. 1990-07-31. PMID:2359027. |
pharmacological evidence for feedback regulation of dopamine metabolism in solid fetal substantia nigra transplants. |
1990-07-31 |
2023-08-11 |
human |
| E Castañeda, I Q Whishaw, T E Robinso. Changes in striatal dopamine neurotransmission assessed with microdialysis following recovery from a bilateral 6-OHDA lesion: variation as a function of lesion size. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 10. issue 6. 1990-07-26. PMID:1693953. |
intracerebral microdialysis was used to measure the extracellular concentration of striatal dopamine (da) and its metabolites in freely moving rats depleted of da by the bilateral infusion of 6-hydroxydopamine into the substantia nigra approximately 1 month earlier. |
1990-07-26 |
2023-08-11 |
rat |
| C C Ouimet, P Greengar. Distribution of DARPP-32 in the basal ganglia: an electron microscopic study. Journal of neurocytology. vol 19. issue 1. 1990-07-16. PMID:2191086. |
darpp-32, a dopamine and cyclic amp-regulated phosphoprotein, has been studied by light and electron microscopical immunocytochemistry in the rat caudatoputamen, globus pallidus and substantia nigra. |
1990-07-16 |
2023-08-11 |
rat |
| J D Elsworth, A Y Deutch, D E Redmond, J R Sladek, R H Rot. MPTP-induced parkinsonism: relative changes in dopamine concentration in subregions of substantia nigra, ventral tegmental area and retrorubral field of symptomatic and asymptomatic vervet monkeys. Brain research. vol 513. issue 2. 1990-07-16. PMID:2350702. |
mptp-induced parkinsonism: relative changes in dopamine concentration in subregions of substantia nigra, ventral tegmental area and retrorubral field of symptomatic and asymptomatic vervet monkeys. |
1990-07-16 |
2023-08-11 |
monkey |
| J D Elsworth, A Y Deutch, D E Redmond, J R Sladek, R H Rot. MPTP-induced parkinsonism: relative changes in dopamine concentration in subregions of substantia nigra, ventral tegmental area and retrorubral field of symptomatic and asymptomatic vervet monkeys. Brain research. vol 513. issue 2. 1990-07-16. PMID:2350702. |
dopamine (da) and homovanillic acid (hva) concentrations were measured in subregions of substantia nigra, ventral tegmental area and retrorubral field in vervet monkeys 1 to 2 months after treatment with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp). |
1990-07-16 |
2023-08-11 |
monkey |
| K Fuxe, A M Janson, A Jansson, K Andersson, P Eneroth, L F Agnat. Chronic nicotine treatment increases dopamine levels and reduces dopamine utilization in substantia nigra and in surviving forebrain dopamine nerve terminal systems after a partial di-mesencephalic hemitransection. Naunyn-Schmiedeberg's archives of pharmacology. vol 341. issue 3. 1990-06-27. PMID:2342600. |
chronic nicotine treatment increases dopamine levels and reduces dopamine utilization in substantia nigra and in surviving forebrain dopamine nerve terminal systems after a partial di-mesencephalic hemitransection. |
1990-06-27 |
2023-08-11 |
rat |
| H Dabadie, N Mons, M Geffar. Simultaneous detection of tryptamine and dopamine in rat substantia nigra and raphe nuclei using specific antibodies. Brain research. vol 512. issue 1. 1990-06-21. PMID:2337800. |
simultaneous detection of tryptamine and dopamine in rat substantia nigra and raphe nuclei using specific antibodies. |
1990-06-21 |
2023-08-11 |
rat |
| L P Martin, R F Cox, B L Waszcza. Efficacy and potency comparisons among aporphine enantiomers: effects on dopamine neurons in substantia nigra of rat. Neuropharmacology. vol 29. issue 2. 1990-05-30. PMID:2184376. |
efficacy and potency comparisons among aporphine enantiomers: effects on dopamine neurons in substantia nigra of rat. |
1990-05-30 |
2023-08-11 |
rat |
| L P Martin, R F Cox, B L Waszcza. Efficacy and potency comparisons among aporphine enantiomers: effects on dopamine neurons in substantia nigra of rat. Neuropharmacology. vol 29. issue 2. 1990-05-30. PMID:2184376. |
extracellular single unit recording studies were carried out on male rats to determine the responses of dopamine neurons of the substantia nigra to intravenous administration of the enantiomers of the aporphine congeners, apomorphine (apo), n-n-propylnorapomorphine (npa) and 11-hydroxy-n-n-propylnorapomorphine (11-oh-npa). |
1990-05-30 |
2023-08-11 |
rat |
| R Romo, W Schult. Somatosensory input to dopamine neurones of the monkey midbrain: responses to pain pinch under anaesthesia and to active touch in behavioural context. Progress in brain research. vol 80. 1990-05-30. PMID:2634283. |
the somatosensory responses of single dopamine (da) neurones were recorded in the pars compacta of substantia nigra and in neighbouring da cell groups of four macaca fascicularis monkeys. |
1990-05-30 |
2023-08-11 |
monkey |
| W Schultz, R Rom. Dopamine neurons of the monkey midbrain: contingencies of responses to stimuli eliciting immediate behavioral reactions. Journal of neurophysiology. vol 63. issue 3. 1990-05-29. PMID:2329364. |
this study investigates the behavioral conditions in which dopamine (da) neurons of substantia nigra and adjoining areas a8 and a10 respond with impulses to visual and auditory trigger stimuli eliciting immediate arm- and eye-movement reactions. |
1990-05-29 |
2023-08-11 |
monkey |
| D R Hill, T M Shaw, W Graham, G N Woodruf. Autoradiographical detection of cholecystokinin-A receptors in primate brain using 125I-Bolton Hunter CCK-8 and 3H-MK-329. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 10. issue 4. 1990-05-25. PMID:2329368. |
high concentrations of cck-a receptors were present in the substantia nigra zona compacta and also the ventral tegmental area and may be associated with dopamine cell bodies. |
1990-05-25 |
2023-08-11 |
monkey |
| E E Jones, F Naftoli. Estrogen effects on the tuberoinfundibular dopaminergic system in the female rat brain. Brain research. vol 510. issue 1. 1990-05-21. PMID:1969760. |
estrogen effects on tyrosine hydroxylase (th), monoamine oxidase types a and b (mao), and dopamine (da) in microdissected regions of the hypothalamus, preoptic area and substantia nigra (snr) of the female rat brain were investigated. |
1990-05-21 |
2023-08-11 |
rat |
| M Yoshid. [Tetrahydroisoquinoline and parkinsonism]. Rinsho shinkeigaku = Clinical neurology. vol 29. issue 12. 1990-05-04. PMID:2630145. |
dopamine, total biopterine and tyrosine hydroxylase (th) were decreased in the substantia nigra of tiq treated monkeys compared to saline treated monkeys (n = 5). |
1990-05-04 |
2023-08-11 |
mouse |
| L C Triarhou, P Brundin, G Doucet, J Norton, A Björklund, B Ghett. Intrastriatal implants of mesencephalic cell suspensions in weaver mutant mice: ultrastructural relationships of dopaminergic dendrites and axons issued from the graft. Experimental brain research. vol 79. issue 1. 1990-04-25. PMID:1968850. |
prior to perfusion, which was carried out at 80 days after transplantation surgery, the grafted striata of the weaver recipients were deprived of their intrinsic mesostriatal dopamine input by local injections of 6-hydroxydopamine into the ipsilateral substantia nigra in order to selectively study the innervation derived from the graft. |
1990-04-25 |
2023-08-11 |
mouse |
| G R Uh. Parkinson's disease: neurotransmitter and neurotoxin receptors and their genes. European neurology. vol 30 Suppl 1. 1990-04-16. PMID:1968832. |
the status of dopamine receptors in the striatum, the possibility that specific neurotoxin receptors exist and the likelihood that receptors in other brain regions, including pathologically involved substantia nigra and cerebral cortex, can provide meaningful information about brain function and the disease are reviewed. |
1990-04-16 |
2023-08-11 |
Not clear |
| H Baker, C A Gree. Region-specific consequences of PCD gene expression in the olfactory system. The Journal of comparative neurology. vol 293. issue 1. 1990-04-16. PMID:1968917. |
moreover, th activity in the substantia nigra also was unchanged, thus suggesting that the dopamine phenotype is resistant to the influences of the pcd gene. |
1990-04-16 |
2023-08-11 |
mouse |
| B M Faggin, J K Zubieta, A H Rezvani, L X Cubedd. Neurotensin-induced dopamine release in vivo and in vitro from substantia nigra and nucleus caudate. The Journal of pharmacology and experimental therapeutics. vol 252. issue 2. 1990-04-16. PMID:2138224. |
neurotensin-induced dopamine release in vivo and in vitro from substantia nigra and nucleus caudate. |
1990-04-16 |
2023-08-11 |
rat |
| B M Faggin, J K Zubieta, A H Rezvani, L X Cubedd. Neurotensin-induced dopamine release in vivo and in vitro from substantia nigra and nucleus caudate. The Journal of pharmacology and experimental therapeutics. vol 252. issue 2. 1990-04-16. PMID:2138224. |
we compared the dopamine (da) releasing effects of neurotensin (nt) from cell bodies (substantia nigra) and nerve terminals (nucleus caudate). |
1990-04-16 |
2023-08-11 |
rat |