| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I Strömberg, C van Horne, M Bygdeman, N Weiner, G A Gerhard. Function of intraventricular human mesencephalic xenografts in immunosuppressed rats: an electrophysiological and neurochemical analysis. Experimental neurology. vol 112. issue 2. 1991-07-02. PMID:1674693. |
much greater levels of dopamine and serotonin were detected in the grafts, compared to in normal rat substantia nigra, as measured with hplc coupled to a 16-channel electrochemical array detector. |
1991-07-02 |
2023-08-11 |
human |
| G S Zubenko, J Moossy, A J Martinez, G Rao, D Claassen, J Rosen, U Kop. Neuropathologic and neurochemical correlates of psychosis in primary dementia. Archives of neurology. vol 48. issue 6. 1991-06-28. PMID:1710105. |
the concentrations of norepinephrine, dopamine, and serotonin, the metabolites of these biogenic amines, and the specific activity of choline acetyltransferase were also determined in these four cortical regions as well as in the substantia nigra, thalamus, amygdala, and caudate nucleus. |
1991-06-28 |
2023-08-11 |
Not clear |
| N L Ostrowski, A R Caggiul. Correlation between locomotor stimulation and the electrophysiological effects of low doses of morphine on substantia nigra dopamine neurons. I. Acute drug administration. The Journal of pharmacology and experimental therapeutics. vol 257. issue 1. 1991-05-24. PMID:2020010. |
correlation between locomotor stimulation and the electrophysiological effects of low doses of morphine on substantia nigra dopamine neurons. |
1991-05-24 |
2023-08-11 |
rat |
| M Santiago, H Rollema, J B de Vries, B H Westerin. Acute effects of intranigral application of MPP+ on nigral and bilateral striatal release of dopamine simultaneously recorded by microdialysis. Brain research. vol 538. issue 2. 1991-05-16. PMID:1707325. |
intracerebral microdialysis in freely moving rats was used to investigate the effects of perfusions with the 1-methyl-4-phenylpyridinium ion (mpp+) in the substantia nigra (sn) on the extracellular levels of dopamine (da), 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva) and 5-hydroxyindoleacetic acid (5-hiaa) in the perfused sn and in the ipsi- and contralateral striata. |
1991-05-16 |
2023-08-11 |
rat |
| R F Seegal, B Bush, K O Brosc. Comparison of effects of Aroclors 1016 and 1260 on non-human primate catecholamine function. Toxicology. vol 66. issue 2. 1991-05-13. PMID:2014516. |
aroclor 1016 significantly decreased concentrations of dopamine and its metabolites in the caudate, putamen, substantia nigra and hypothalamus but did not alter neurotransmitter or metabolite concentrations in the globus pallidus and hippocampus. |
1991-05-13 |
2023-08-11 |
monkey |
| R F Seegal, B Bush, K O Brosc. Comparison of effects of Aroclors 1016 and 1260 on non-human primate catecholamine function. Toxicology. vol 66. issue 2. 1991-05-13. PMID:2014516. |
aroclor 1260 reduced dopamine concentrations in the caudate, putamen and hypothalamus but produced no effects in the substantia nigra, globus pallidus or hippocampus. |
1991-05-13 |
2023-08-11 |
monkey |
| M S Reid, M Herrera-Marschitz, J Kehr, U Ungersted. Striatal dopamine and glutamate release: effects of intranigral injections of substance P. Acta physiologica Scandinavica. vol 140. issue 4. 1991-05-07. PMID:1707211. |
unilateral injections of substance p (0.07 nmol) into the substantia nigra, pars reticulata enhanced the levels of dopamine and glutamate in the ipsilateral striatum. |
1991-05-07 |
2023-08-11 |
rat |
| R F Cox, B L Waszcza. Irreversible receptor inactivation reveals differences in dopamine receptor reserve between A9 and A10 dopamine systems: an electrophysiological analysis. Brain research. vol 534. issue 1-2. 1991-04-18. PMID:1981482. |
partial receptor inactivation was used as a tool to examine whether differences in receptor reserve exist between the dopamine receptor populations which mediate responses of substantia nigra (a9) and ventral tegmental area (a10) dopamine neurons to dopamine agonist drugs. |
1991-04-18 |
2023-08-11 |
rat |
| J De Keyser, J P De Backer, G Vauquelin, G Ebinge. D1 and D2 dopamine receptors in human substantia nigra: localization and the effect of aging. Journal of neurochemistry. vol 56. issue 4. 1991-04-15. PMID:1825842. |
d1 and d2 dopamine receptors in human substantia nigra: localization and the effect of aging. |
1991-04-15 |
2023-08-11 |
human |
| J De Keyser, J P De Backer, G Vauquelin, G Ebinge. D1 and D2 dopamine receptors in human substantia nigra: localization and the effect of aging. Journal of neurochemistry. vol 56. issue 4. 1991-04-15. PMID:1825842. |
since nigrostriatal dopaminergic neurons degenerate with aging, these results suggest either that the nigral d2 receptors are up-regulated in response to a progressive depletion of dopamine in the substantia nigra or that, in contrast to the rat, they are not located on dopaminergic neurons. |
1991-04-15 |
2023-08-11 |
human |
| M Santiago, B H Westerink, H Rollem. Responsiveness of striatal dopamine release in awake animals after chronic 1-methyl-4-phenylpyridinium ion-induced lesions of the substantia nigra. Journal of neurochemistry. vol 56. issue 4. 1991-04-15. PMID:2002346. |
responsiveness of striatal dopamine release in awake animals after chronic 1-methyl-4-phenylpyridinium ion-induced lesions of the substantia nigra. |
1991-04-15 |
2023-08-11 |
rat |
| M Santiago, B H Westerink, H Rollem. Responsiveness of striatal dopamine release in awake animals after chronic 1-methyl-4-phenylpyridinium ion-induced lesions of the substantia nigra. Journal of neurochemistry. vol 56. issue 4. 1991-04-15. PMID:2002346. |
extracellular concentrations of dopamine (da), 3,4-dihydroxyphenylacetic acid (dopac), and homovanillic acid were measured by microdialysis in rat striatum 1 month after a unilateral infusion via a dialysis probe of a high concentration (10 mm) of 1-methyl-4-phenylpyridinium ion (mpp+) into the substantia nigra. |
1991-04-15 |
2023-08-11 |
rat |
| T M Dawson, V L Dawson, F H Gage, L J Fisher, M A Hunt, J K Wamsle. Functional recovery of supersensitive dopamine receptors after intrastriatal grafts of fetal substantia nigra. Experimental neurology. vol 111. issue 3. 1991-04-08. PMID:1825638. |
functional recovery of supersensitive dopamine receptors after intrastriatal grafts of fetal substantia nigra. |
1991-04-08 |
2023-08-11 |
rat |
| R Meloni, K Gal. Differential regulation of dopamine metabolism in solid fetal substantia nigra transplants and their terminals in the host striatum. Progress in brain research. vol 82. 1991-04-04. PMID:2127112. |
differential regulation of dopamine metabolism in solid fetal substantia nigra transplants and their terminals in the host striatum. |
1991-04-04 |
2023-08-11 |
Not clear |
| I Irwin, L E DeLanney, L S Forno, K T Finnegan, D A Di Monte, J W Langsto. The evolution of nigrostriatal neurochemical changes in the MPTP-treated squirrel monkey. Brain research. vol 531. issue 1-2. 1991-04-01. PMID:1981162. |
the behavioral effects and the concentrations of dopamine (da), dihydroxyphenylacetic acid and homovanillic acid were determined in caudate, putamen and substantia nigra 1, 3, 5 (n = 3/time point) and 10 days (n = 6) after drug administration. |
1991-04-01 |
2023-08-11 |
mouse |
| J R Hollerman, A A Grac. The effects of dopamine-depleting brain lesions on the electrophysiological activity of rat substantia nigra dopamine neurons. Brain research. vol 533. issue 2. 1991-04-01. PMID:2126975. |
the effects of dopamine-depleting brain lesions on the electrophysiological activity of rat substantia nigra dopamine neurons. |
1991-04-01 |
2023-08-11 |
rat |
| M S Reid, M Herrera-Marschitz, T Hökfelt, N Lindefors, H Persson, U Ungersted. Striatonigral GABA, dynorphin, substance P and neurokinin A modulation of nigrostriatal dopamine release: evidence for direct regulatory mechanisms. Experimental brain research. vol 82. issue 2. 1991-03-22. PMID:1704847. |
this was investigated by measuring extracellular dopamine levels in the striatum, using microdialysis, after injections of gaba (300 nmol/0.2 microliters), dynorphin a (0.5 nmol/0.2 microliters), substance p (0.07 mnol/0.2 microliters) or neurokinin a (0.09 nmol/0.2 microliters) into the ipsilateral substantia nigra, pars reticulata (snr). |
1991-03-22 |
2023-08-11 |
rat |
| M S Reid, T Hökfelt, M Herrera-Marschitz, R Håkanson, D M Feng, K Folkers, M Goldstein, U Ungersted. Intranigral substance P stimulation of striatal dopamine release is inhibited by spantide II: a new tachykinin antagonist without apparent neurotoxicity. Brain research. vol 532. issue 1-2. 1991-03-21. PMID:1704289. |
a unilateral injection (all substances were injected in a volume of 0.2 microliter) of spantide ii (0.7 nmol) into the substantia nigra, pars reticulata (snr) of halothane anaesthetized rats produced a short-lasting decrease in dopamine levels in the ipsilateral striatum. |
1991-03-21 |
2023-08-11 |
rat |
| P B Silverma. Classically conditioned ethanol stimulus control of a motor behavior. Alcohol (Fayetteville, N.Y.). vol 7. issue 6. 1991-02-04. PMID:2261085. |
rats with extensive unilateral 6-hydroxydopamine lesions of substantia nigra rotate (turn in circles) in response to administration of dopamine agonists. |
1991-02-04 |
2023-08-11 |
rat |
| G Buzsáki, I Laszlovszky, A Lajtha, C Vadás. Spike-and-wave neocortical patterns in rats: genetic and aminergic control. Neuroscience. vol 38. issue 2. 1991-02-01. PMID:2263319. |
in addition, tyrosine hydroxylase activity and dopamine d2 receptor density were determined in the substantia nigra, corpus striatum, olfactory tubercle and ponsmedulla areas of fisher 344 and buffalo animals. |
1991-02-01 |
2023-08-11 |
human |