| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T M Dawson, V L Dawson, F H Gage, L J Fisher, M A Hunt, J K Wamsle. Functional recovery of supersensitive dopamine receptors after intrastriatal grafts of fetal substantia nigra. Experimental neurology. vol 111. issue 3. 1991-04-08. PMID:1825638. |
functional recovery of supersensitive dopamine receptors after intrastriatal grafts of fetal substantia nigra. |
1991-04-08 |
2023-08-11 |
rat |
| R Meloni, K Gal. Differential regulation of dopamine metabolism in solid fetal substantia nigra transplants and their terminals in the host striatum. Progress in brain research. vol 82. 1991-04-04. PMID:2127112. |
differential regulation of dopamine metabolism in solid fetal substantia nigra transplants and their terminals in the host striatum. |
1991-04-04 |
2023-08-11 |
Not clear |
| I Irwin, L E DeLanney, L S Forno, K T Finnegan, D A Di Monte, J W Langsto. The evolution of nigrostriatal neurochemical changes in the MPTP-treated squirrel monkey. Brain research. vol 531. issue 1-2. 1991-04-01. PMID:1981162. |
the behavioral effects and the concentrations of dopamine (da), dihydroxyphenylacetic acid and homovanillic acid were determined in caudate, putamen and substantia nigra 1, 3, 5 (n = 3/time point) and 10 days (n = 6) after drug administration. |
1991-04-01 |
2023-08-11 |
mouse |
| J R Hollerman, A A Grac. The effects of dopamine-depleting brain lesions on the electrophysiological activity of rat substantia nigra dopamine neurons. Brain research. vol 533. issue 2. 1991-04-01. PMID:2126975. |
the effects of dopamine-depleting brain lesions on the electrophysiological activity of rat substantia nigra dopamine neurons. |
1991-04-01 |
2023-08-11 |
rat |
| M S Reid, M Herrera-Marschitz, T Hökfelt, N Lindefors, H Persson, U Ungersted. Striatonigral GABA, dynorphin, substance P and neurokinin A modulation of nigrostriatal dopamine release: evidence for direct regulatory mechanisms. Experimental brain research. vol 82. issue 2. 1991-03-22. PMID:1704847. |
this was investigated by measuring extracellular dopamine levels in the striatum, using microdialysis, after injections of gaba (300 nmol/0.2 microliters), dynorphin a (0.5 nmol/0.2 microliters), substance p (0.07 mnol/0.2 microliters) or neurokinin a (0.09 nmol/0.2 microliters) into the ipsilateral substantia nigra, pars reticulata (snr). |
1991-03-22 |
2023-08-11 |
rat |
| M S Reid, T Hökfelt, M Herrera-Marschitz, R Håkanson, D M Feng, K Folkers, M Goldstein, U Ungersted. Intranigral substance P stimulation of striatal dopamine release is inhibited by spantide II: a new tachykinin antagonist without apparent neurotoxicity. Brain research. vol 532. issue 1-2. 1991-03-21. PMID:1704289. |
a unilateral injection (all substances were injected in a volume of 0.2 microliter) of spantide ii (0.7 nmol) into the substantia nigra, pars reticulata (snr) of halothane anaesthetized rats produced a short-lasting decrease in dopamine levels in the ipsilateral striatum. |
1991-03-21 |
2023-08-11 |
rat |
| P B Silverma. Classically conditioned ethanol stimulus control of a motor behavior. Alcohol (Fayetteville, N.Y.). vol 7. issue 6. 1991-02-04. PMID:2261085. |
rats with extensive unilateral 6-hydroxydopamine lesions of substantia nigra rotate (turn in circles) in response to administration of dopamine agonists. |
1991-02-04 |
2023-08-11 |
rat |
| G Buzsáki, I Laszlovszky, A Lajtha, C Vadás. Spike-and-wave neocortical patterns in rats: genetic and aminergic control. Neuroscience. vol 38. issue 2. 1991-02-01. PMID:2263319. |
in addition, tyrosine hydroxylase activity and dopamine d2 receptor density were determined in the substantia nigra, corpus striatum, olfactory tubercle and ponsmedulla areas of fisher 344 and buffalo animals. |
1991-02-01 |
2023-08-11 |
human |
| M S Reid, M Herrera-Marschitz, L Terenius, U Ungersted. Intranigral substance P modulation of striatal dopamine: interaction with N-terminal and C-terminal substance P fragments. Brain research. vol 526. issue 2. 1991-01-31. PMID:1701682. |
the effects of unilateral injections of two substance p fragments, the n-terminal substance p (1-7) (sp1-7) and the c-terminal substance p (6-11) (sp6-11) into the substantia nigra, pars reticulata on dopamine (da) release in the ipsilateral striatum of halothane-anaesthetized rats were studied using microdialysis. |
1991-01-31 |
2023-08-11 |
rat |
| T Yamada, P L McGeer, K G Baimbridge, E G McGee. Relative sparing in Parkinson's disease of substantia nigra dopamine neurons containing calbindin-D28K. Brain research. vol 526. issue 2. 1991-01-31. PMID:2257487. |
relative sparing in parkinson's disease of substantia nigra dopamine neurons containing calbindin-d28k. |
1991-01-31 |
2023-08-11 |
Not clear |
| J S Kroin, L C Kao, T J Zhang, R D Penn, H L Klawans, P M Carve. Dopamine distribution and behavioral alterations resulting from dopamine infusion into the brain of the lesioned rat. Journal of neurosurgery. vol 74. issue 1. 1991-01-28. PMID:1984488. |
in an effort to verify the "dopamine secretion hypothesis" as the mechanism responsible for the antiparkinsonian efficacy of adrenal medullary transplants into the brain, the effects of dopamine infusion into the brains of rats with unilateral substantia nigra lesions were examined. |
1991-01-28 |
2023-08-11 |
rat |
| F Javoy-Agid, E C Hirsch, S Dumas, C Duyckaerts, J Mallet, Y Agi. Decreased tyrosine hydroxylase messenger RNA in the surviving dopamine neurons of the substantia nigra in Parkinson's disease: an in situ hybridization study. Neuroscience. vol 38. issue 1. 1991-01-24. PMID:1979431. |
decreased tyrosine hydroxylase messenger rna in the surviving dopamine neurons of the substantia nigra in parkinson's disease: an in situ hybridization study. |
1991-01-24 |
2023-08-11 |
Not clear |
| R F Seegal, B Bush, W Shai. Lightly chlorinated ortho-substituted PCB congeners decrease dopamine in nonhuman primate brain and in tissue culture. Toxicology and applied pharmacology. vol 106. issue 1. 1991-01-17. PMID:2123577. |
exposure of the nonhuman primate, macaca nemestrina, to aroclor 1016, a commercial mixture of 26 lightly chlorinated pcb congeners, decreased dopamine concentrations in the caudate, putamen, substantia nigra, and hypothalamus. |
1991-01-17 |
2023-08-11 |
monkey |
| O Giorgi, M L Porceddu, S Pepitoni, G P Serra, G Toffano, G Biggi. Differential effect of aging on 3H-SCH 23390 binding sites in the retina and in distinct areas of the rat brain. Journal of neural transmission. General section. vol 82. issue 3. 1991-01-15. PMID:2248731. |
the effects of age on the binding parameters of the selective d-1 dopamine (da) receptor antagonist 3h-sch 23390 were studied in membrane preparations from rat striatum, substantia nigra, olfactory tubercle, prefrontal cortex and retina. |
1991-01-15 |
2023-08-11 |
rat |
| D J Sirinathsinghji, S B Dunnett, A J Northrop, B J Morri. Experimental hemiparkinsonism in the rat following chronic unilateral infusion of MPP+ into the nigrostriatal dopamine pathway--III. Reversal by embryonic nigral dopamine grafts. Neuroscience. vol 37. issue 3. 1991-01-08. PMID:2247221. |
in all the animals of the lesioned and grafted groups there was a complete loss of dopamine neurons in the ipsilateral substantia nigra as demonstrated by tyrosine hydroxylase-immunohistochemistry and in-situ hybridization histochemistry. |
1991-01-08 |
2023-08-11 |
rat |
| T L Perry, J M Wright, K Berry, S Hansen, T L Perr. Dominantly inherited apathy, central hypoventilation, and Parkinson's syndrome: clinical, biochemical, and neuropathologic studies of 2 new cases. Neurology. vol 40. issue 12. 1991-01-07. PMID:2247238. |
neurochemical studies showed a marked depletion of dopamine in substantia nigra, putamen, and caudate nucleus, as well as reduction in serotonin content in the substantia nigra. |
1991-01-07 |
2023-08-11 |
Not clear |
| K M Merchant, L G Bush, J W Gibb, G R Hanso. Neurotensin-dopamine interactions in the substantia nigra of the rat brain. The Journal of pharmacology and experimental therapeutics. vol 255. issue 2. 1990-12-31. PMID:2147039. |
single or multiple doses of the potent dopamine releaser, methamphetamine (meth), increases the content of neurotensin (nt)-like immunoreactivity (ntli) in the substantia nigra of the rat brain by 2- to 3-fold. |
1990-12-31 |
2023-08-11 |
rat |
| K M Merchant, L G Bush, J W Gibb, G R Hanso. Neurotensin-dopamine interactions in the substantia nigra of the rat brain. The Journal of pharmacology and experimental therapeutics. vol 255. issue 2. 1990-12-31. PMID:2147039. |
these results suggest that activation of d-1 receptors by endogenous dopamine results in an increase in the level of ntli in the substantia nigra. |
1990-12-31 |
2023-08-11 |
rat |
| K M Merchant, L G Bush, J W Gibb, G R Hanso. Neurotensin-dopamine interactions in the substantia nigra of the rat brain. The Journal of pharmacology and experimental therapeutics. vol 255. issue 2. 1990-12-31. PMID:2147039. |
in addition to the effects of direct or indirect stimulation of dopamine activity on nigral nt levels, basally released dopamine also appeared to regulate the level of ntli in the substantia nigra. |
1990-12-31 |
2023-08-11 |
rat |
| K M Merchant, L G Bush, J W Gibb, G R Hanso. Neurotensin-dopamine interactions in the substantia nigra of the rat brain. The Journal of pharmacology and experimental therapeutics. vol 255. issue 2. 1990-12-31. PMID:2147039. |
thus, interruption of tonic dopamine activity by reserpine-induced depletion of dopamine significantly reduced the level of ntli in the substantia nigra. |
1990-12-31 |
2023-08-11 |
rat |