| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N B Mercuri, F Stratta, P Calabresi, G Bernard. Nomifensine but not amantadine increases dopamine-induced responses on rat substantia nigra zona compacta neurons. Neuroscience letters. vol 131. issue 2. 1992-02-12. PMID:1662338. |
by contrast, the superfusion of amantadine (1-30 microm) on substantia nigra zona compacta cells was ineffective on firing rate, membrane potential or on sensitivity to exogenous dopamine. |
1992-02-12 |
2023-08-11 |
rat |
| N B Mercuri, F Stratta, P Calabresi, G Bernard. Nomifensine but not amantadine increases dopamine-induced responses on rat substantia nigra zona compacta neurons. Neuroscience letters. vol 131. issue 2. 1992-02-12. PMID:1662338. |
while our results provide electrophysiological evidence for an inhibition of the dopamine uptake system by nomifensine, they do not support a dopaminergic mechanism for the actions of amantadine in the substantia nigra zona compacta. |
1992-02-12 |
2023-08-11 |
rat |
| S C Hu, F W Chang, Y J Sung, W M Hsu, E H Le. Neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the substantia nigra and the locus coeruleus in BALB/c mice. The Journal of pharmacology and experimental therapeutics. vol 259. issue 3. 1992-02-07. PMID:1684822. |
the purpose of the present study was to determine whether 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp), administered systemically or as a local infusion, has a direct neurotoxic action upon dopamine (da) neurons in the substantia nigra (sn) and norepinephrine (ne) neurons in the locus coeruleus (lc) in balb/c mice. |
1992-02-07 |
2023-08-11 |
mouse |
| T B Usdin, E Mezey, C Chen, M J Brownstein, B J Hoffma. Cloning of the cocaine-sensitive bovine dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 24. 1992-02-07. PMID:1722321. |
a cdna encoding the dopamine transporter from bovine brain substantia nigra was identified on the basis of its structural homology to other, recently cloned, neurotransmitter transporters. |
1992-02-07 |
2023-08-11 |
human |
| T B Usdin, E Mezey, C Chen, M J Brownstein, B J Hoffma. Cloning of the cocaine-sensitive bovine dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 24. 1992-02-07. PMID:1722321. |
dopamine transporter mrna was detected by in situ hybridization in the substantia nigra but not in the locus coeruleus, raphe, caudate, or other brain areas. |
1992-02-07 |
2023-08-11 |
human |
| A Cintra, Y H Cao, C Oellig, B Tinner, F Bortolotti, M Goldstein, R F Pettersson, K Fux. Basic FGF is present in dopaminergic neurons of the ventral midbrain of the rat. Neuroreport. vol 2. issue 10. 1992-02-04. PMID:1684518. |
immunocytochemistry procedures and 6-hydroxy-dopamine-induced degeneration of dopamine nerve cells provided evidence that practically all tyrosine hydroxylase immunoreactive (ir) neurons of the substantia nigra and ventral tegmental area contain cytoplasmic basic fibroblast growth factor immunoreactivity (bfgf ir), while many astroglial cells in the neostriatum and substantia nigra contain nuclear bfgf ir. |
1992-02-04 |
2023-08-11 |
rat |
| A J Daniels, J Abarc. Effect of intranigral Mn2+ on striatal and nigral synthesis and levels of dopamine and cofactor. Neurotoxicology and teratology. vol 13. issue 5. 1992-02-04. PMID:1684634. |
a single injection of manganese chloride into the rat substantia nigra caused a significant and reversible drop in nigral and striatal dopamine and cofactor content ipsilateral to the lesion. |
1992-02-04 |
2023-08-11 |
rat |
| P D Shepard, B S Bunne. Repetitive firing properties of putative dopamine-containing neurons in vitro: regulation by an apamin-sensitive Ca(2+)-activated K+ conductance. Experimental brain research. vol 86. issue 1. 1992-01-31. PMID:1756785. |
intracellular recording techniques were used to study the effects of apamin (apa), a selective inhibitor of one type of ca(2+)-activated k+ channel, on the electroresponsive properties of dopamine (da)-containing neurons within the zona compacta of the substantia nigra (snc) in rat. |
1992-01-31 |
2023-08-11 |
rat |
| C Pifl, G Schingnitz, O Hornykiewic. Effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on the regional distribution of brain monoamines in the rhesus monkey. Neuroscience. vol 44. issue 3. 1992-01-24. PMID:1754053. |
profound dopamine loss in caudate nucleus, putamen and substantia nigra. |
1992-01-24 |
2023-08-11 |
monkey |
| A Elverfors, H Nissbrand. Reserpine-insensitive dopamine release in the substantia nigra? Brain research. vol 557. issue 1-2. 1992-01-22. PMID:1720998. |
reserpine-insensitive dopamine release in the substantia nigra? |
1992-01-22 |
2023-08-11 |
Not clear |
| A Elverfors, H Nissbrand. Reserpine-insensitive dopamine release in the substantia nigra? Brain research. vol 557. issue 1-2. 1992-01-22. PMID:1720998. |
dopamine (da) is synthesized and released not only from the terminals of the nigrostriatal dopaminergic pathway, but also from the dendrites in the substantia nigra (sn). |
1992-01-22 |
2023-08-11 |
Not clear |
| M Marchi, A Augliera, A Codignola, G Lunardi, E Fedele, G Fontana, M Raiter. Cholinergic modulation of [3H]dopamine release from dendrosomes of rat substantia nigra. Naunyn-Schmiedeberg's archives of pharmacology. vol 344. issue 3. 1992-01-09. PMID:1961254. |
cholinergic modulation of [3h]dopamine release from dendrosomes of rat substantia nigra. |
1992-01-09 |
2023-08-11 |
rat |
| M Marchi, A Augliera, A Codignola, G Lunardi, E Fedele, G Fontana, M Raiter. Cholinergic modulation of [3H]dopamine release from dendrosomes of rat substantia nigra. Naunyn-Schmiedeberg's archives of pharmacology. vol 344. issue 3. 1992-01-09. PMID:1961254. |
dendrosomes prepared from substantia nigra are able to take up and release [3h]dopamine in a ca(2+)-dependent manner. |
1992-01-09 |
2023-08-11 |
rat |
| M Marchi, A Augliera, A Codignola, G Lunardi, E Fedele, G Fontana, M Raiter. Cholinergic modulation of [3H]dopamine release from dendrosomes of rat substantia nigra. Naunyn-Schmiedeberg's archives of pharmacology. vol 344. issue 3. 1992-01-09. PMID:1961254. |
the vmax values of [3h]dopamine uptake in substantia nigra dendrosomes was about 5 times lower than that in caudate putamen synaptosomes. |
1992-01-09 |
2023-08-11 |
rat |
| M Marchi, A Augliera, A Codignola, G Lunardi, E Fedele, G Fontana, M Raiter. Cholinergic modulation of [3H]dopamine release from dendrosomes of rat substantia nigra. Naunyn-Schmiedeberg's archives of pharmacology. vol 344. issue 3. 1992-01-09. PMID:1961254. |
the pattern of the k(+)-dependency of the [3h]dopamine release in substantia nigra dendrosomes was significantly different from that found in caudate putamen synaptosomes. |
1992-01-09 |
2023-08-11 |
rat |
| M Marchi, A Augliera, A Codignola, G Lunardi, E Fedele, G Fontana, M Raiter. Cholinergic modulation of [3H]dopamine release from dendrosomes of rat substantia nigra. Naunyn-Schmiedeberg's archives of pharmacology. vol 344. issue 3. 1992-01-09. PMID:1961254. |
the data suggest the existence, in the substantia nigra of the rat, of two distinct muscarinic receptor subtypes regulating respectively dopamine release from dopamine dendrites and acetylcholine release from cholinergic nerve terminals. |
1992-01-09 |
2023-08-11 |
rat |
| P Robledo, J Fege. Acute monoaminergic depletion in the rat potentiates the excitatory effect of the subthalamic nucleus in the substantia nigra pars reticulata but not in the pallidal complex. Journal of neural transmission. General section. vol 86. issue 2. 1992-01-02. PMID:1683238. |
recent neurochemical evidence suggests that chemical or electrical stimulation of the subthalamic nucleus (sth) increases dopamine release in the substantia nigra (sn) with a subsequent decrease in the striatum. |
1992-01-02 |
2023-08-11 |
rat |
| S Ceccatelli, P Ernfors, M J Villar, H Persson, T Hökfel. Expanded distribution of mRNA for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the rat brain after colchicine treatment. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 22. 1991-12-26. PMID:1946455. |
thus, ngf mrna was present, for example, in many motor nuclei and in the basal forebrain, and bdnf mrna was seen in many nuclei in the brain stem and in catecholamine neurons, including dopamine neurons in the substantia nigra. |
1991-12-26 |
2023-08-11 |
rat |
| E Stefanini, M Frau, G L Gess. Increase in D2 dopamine receptors in the substantia nigra after chronic (-)-sulpiride treatment. Brain research. vol 555. issue 2. 1991-12-23. PMID:1834311. |
increase in d2 dopamine receptors in the substantia nigra after chronic (-)-sulpiride treatment. |
1991-12-23 |
2023-08-11 |
rat |
| E Stefanini, M Frau, G L Gess. Increase in D2 dopamine receptors in the substantia nigra after chronic (-)-sulpiride treatment. Brain research. vol 555. issue 2. 1991-12-23. PMID:1834311. |
changes in d2 dopamine (da) receptors in the substantia nigra (sn) and caudate nucleus (cn) homogenates were studied in rats following chronic treatment with the specific d2 receptor antagonist (-)-sulpiride (50 mg/kg s.c. twice daily for 8 days). |
1991-12-23 |
2023-08-11 |
rat |