| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Hervé, F Trovero, G Blanc, J Glowinski, J P Tassi. Autoradiographic identification of D1 dopamine receptors labelled with [3H]dopamine: distribution, regulation and relationship to coupling. Neuroscience. vol 46. issue 3. 1992-04-13. PMID:1532052. |
this was particularly the case in the substantia nigra, some amygdaloid nuclei and the prefrontal cortex--structures in which the ratios between [3h]sch23390 and [3h]dopamine binding sites were more than seven-fold higher than that observed in the striatum. |
1992-04-13 |
2023-08-11 |
rat |
| D Hervé, F Trovero, G Blanc, J Glowinski, J P Tassi. Autoradiographic identification of D1 dopamine receptors labelled with [3H]dopamine: distribution, regulation and relationship to coupling. Neuroscience. vol 46. issue 3. 1992-04-13. PMID:1532052. |
in addition, a lower coupling of d1 receptors with adenylate cyclase was observed in the substantia nigra when compared to that in the striatum: this may explain the relatively weak [3h]dopamine binding in the substantia nigra. |
1992-04-13 |
2023-08-11 |
rat |
| N R Oakley, A G Hayes, M J Sheeha. Effect of typical and atypical neuroleptics on the behavioural consequences of activation by muscimol of mesolimbic and nigro-striatal dopaminergic pathways in the rat. Psychopharmacology. vol 105. issue 2. 1992-04-07. PMID:1686655. |
direct injections of muscimol into the ventral tegmental area (vta) or substantia nigra zona reticulata (snr) have been used to selectively stimulate the mesolimbic and nigro-striatal dopamine pathways respectively. |
1992-04-07 |
2023-08-11 |
rat |
| M E Hall, J M Stewar. The substance P fragment SP(1-7) stimulates motor behavior and nigral dopamine release. Pharmacology, biochemistry, and behavior. vol 41. issue 1. 1992-04-02. PMID:1371611. |
earlier studies have shown that the undecapeptide substance p (sp) alters motor behavior and dopamine metabolism following injection into the substantia nigra (sn) in rat, even though the sn appears largely devoid of sp-specific (nk-1) receptors. |
1992-04-02 |
2023-08-11 |
rat |
| D Orosz, J P Bennet. Simultaneous microdialysis in striatum and substantia nigra suggests that the nigra is a major site of action of L-dihydroxyphenylalanine in the "hemiparkinsonian" rat. Experimental neurology. vol 115. issue 3. 1992-04-02. PMID:1537396. |
we used simultaneous microdialysis of striatum and ipsilateral substantia nigra to characterize changes in extracellular fluid (ecf) levels of dopamine (da) following systemic treatment with l-dopa (25 mg/kg as methylester) in awake, normal rats and those with partial (less than 99%) or complete (greater than 99%) da depleting unilateral lesions of the nigrostriatal pathway (nsp). |
1992-04-02 |
2023-08-11 |
rat |
| K Wakamatsu, S Ito, T Nagats. Cysteinyldopamine is not incorporated into neuromelanin. Neuroscience letters. vol 131. issue 1. 1992-04-02. PMID:1791980. |
the pigment of human substantia nigra, neuromelanin, has been thought to be derived from dopamine. |
1992-04-02 |
2023-08-11 |
human |
| J S McKenzie, A D Shafton, C A Stewar. Intrastriatal dopaminergic agents, muscarinic stimulation, and GABA antagonism compared for rotation responses in rats. Behavioural brain research. vol 45. issue 2. 1992-03-27. PMID:1686398. |
we tested the common hypothesis that rotation on systemic injection of dopaminergic agents in rats with unilateral 6-hydroxydopamine lesions of the substantia nigra is attributable to unequal stimulation of dopamine receptors between the two striata. |
1992-03-27 |
2023-08-11 |
rat |
| H Y Chen, Y P Lin, E H Le. Cholinergic and GABAergic mediations of the effects of apomorphine on serotonin neurons. Synapse (New York, N.Y.). vol 10. issue 1. 1992-03-24. PMID:1371366. |
we have previously demonstrated that these effects are indirectly mediated through dopamine (da) autoreceptors in the substantia nigra and possibly gamma-aminobutyric acid (gaba) neurons in or near the dr. |
1992-03-24 |
2023-08-11 |
Not clear |
| M Bourin, J Bradwejn, D Koszyck. [Is cholecystokinin a biological support in panic attacks?]. L'Encephale. vol 17. issue 5. 1992-03-24. PMID:1686250. |
cck-8s has been shown to coexist with neurotensin and dopamine in neurons projecting from the ventral tegmental area to the nucleus accumbens, and to a lesser extent in neurons of the substantia nigra projecting to periventricular regions of the caudate. |
1992-03-24 |
2023-08-11 |
Not clear |
| M E Old. Enhanced dopamine metabolism in accumbens leads to motor activity and concurrently to increased output from nondopamine neurons in ventral tegmental area and substantia nigra. Physiology & behavior. vol 51. issue 1. 1992-03-23. PMID:1311110. |
enhanced dopamine metabolism in accumbens leads to motor activity and concurrently to increased output from nondopamine neurons in ventral tegmental area and substantia nigra. |
1992-03-23 |
2023-08-11 |
rat |
| G C Parker, E L Rugg, P Win. Cholinergic stimulation of substantia nigra: abolition of carbachol-induced eating by unilateral 6-hydroxydopamine lesion of nigrostriatal dopamine neurones. Experimental brain research. vol 87. issue 3. 1992-03-13. PMID:1723691. |
cholinergic stimulation of substantia nigra: abolition of carbachol-induced eating by unilateral 6-hydroxydopamine lesion of nigrostriatal dopamine neurones. |
1992-03-13 |
2023-08-11 |
rat |
| L W Toled. The postanesthesia patient with Parkinson's disease. Journal of post anesthesia nursing. vol 7. issue 1. 1992-03-12. PMID:1531238. |
concentrations of dopamine and acetylcholine, neurotransmitters in the substantia nigra of the basal ganglia, become imbalanced. |
1992-03-12 |
2023-08-11 |
Not clear |
| S Przedborski, V Jackson-Lewis, S Popilskis, V Kostic, M Levivier, S Fahn, J L Cade. Unilateral MPTP-induced parkinsonism in monkeys. A quantitative autoradiographic study of dopamine D1 and D2 receptors and re-uptake sites. Neuro-Chirurgie. vol 37. issue 6. 1992-03-11. PMID:1780015. |
in contrast, no changes in [3h]-sch 23390-labelled d1 dopamine receptors were observed at the level of either the striatum or the substantia nigra. |
1992-03-11 |
2023-08-11 |
monkey |
| M Mavridis, F C Colpaert, M J Milla. Differential modulation of (+)-amphetamine-induced rotation in unilateral substantia nigra-lesioned rats by alpha 1 as compared to alpha 2 agonists and antagonists. Brain research. vol 562. issue 2. 1992-03-03. PMID:1685341. |
in rats sustaining unilateral 6-hydroxy-dopamine lesions of the substantia nigra (sn), the indirect dopaminergic agonist, (+)-amphetamine (amph), dose-dependently induced robust, ipsilateral rotation: this could be dose-dependently abolished by the dopamine (d2/d1) antagonist, haloperidol. |
1992-03-03 |
2023-08-11 |
rat |
| J Grenhoff, A M Janson, T H Svensson, K Fux. Chronic continuous nicotine treatment causes decreased burst firing of nigral dopamine neurons in rats partially hemitransected at the meso-diencephalic junction. Brain research. vol 562. issue 2. 1992-03-03. PMID:1773346. |
chronic continuous administration of nicotine (0.125 mg/kg/h, 14 days) to male sprague-dawley rats with a partial hemitransection at the meso-diencephalic junction caused a significant reduction in burst firing of remaining dopamine (da) neurons in the zona compacta, substantia nigra, whereas neither the firing rate nor the number of spontaneously active da cells per track were altered in comparison with saline-treated, hemitransected controls. |
1992-03-03 |
2023-08-11 |
rat |
| H Nissbrandt, G Engberg, E Pilebla. The effects of GBR 12909, a dopamine re-uptake inhibitor, on monoaminergic neurotransmission in rat striatum, limbic forebrain, cortical hemispheres and substantia nigra. Naunyn-Schmiedeberg's archives of pharmacology. vol 344. issue 1. 1992-03-02. PMID:1663587. |
the effects of gbr 12909, a dopamine re-uptake inhibitor, on monoaminergic neurotransmission in rat striatum, limbic forebrain, cortical hemispheres and substantia nigra. |
1992-03-02 |
2023-08-11 |
rat |
| H Nissbrandt, G Engberg, E Pilebla. The effects of GBR 12909, a dopamine re-uptake inhibitor, on monoaminergic neurotransmission in rat striatum, limbic forebrain, cortical hemispheres and substantia nigra. Naunyn-Schmiedeberg's archives of pharmacology. vol 344. issue 1. 1992-03-02. PMID:1663587. |
in order to investigate the physiological importance of the membrane pump in eliminating released dopamine (da) we have studied the effects of the putative selective dopamine re-uptake inhibitor, gbr 12909, on synthesis and metabolism of monoamines in the rat striatum, limbic forebrain, cortical hemispheres and substantia nigra (sn). |
1992-03-02 |
2023-08-11 |
rat |
| C E Greenwood, W G Tatton, N A Seniuk, F G Biddl. Increased dopamine synthesis in aging substantia nigra neurons. Neurobiology of aging. vol 12. issue 5. 1992-02-21. PMID:1685220. |
increased dopamine synthesis in aging substantia nigra neurons. |
1992-02-21 |
2023-08-11 |
mouse |
| M P Martres, P Sokoloff, B Giros, J C Schwart. Effects of dopaminergic transmission interruption on the D2 receptor isoforms in various cerebral tissues. Journal of neurochemistry. vol 58. issue 2. 1992-02-13. PMID:1309568. |
unilateral degeneration of dopamine neurons induced by local injection of 6-hydroxydopamine resulted in a marked decrease in levels of total d2 receptor mrnas in substantia nigra (-79%) and ventral tegmental (-63%) area, two cell body areas. |
1992-02-13 |
2023-08-11 |
rat |
| J Lappalainen, J Hietala, M Koulu, B Sjöholm, E Syvälaht. Effects of acute administration of SCH 23390 on dopamine and serotonin turnover in major dopaminergic areas and mesencephalic raphe nuclei--comparison with ritanserin. Progress in neuro-psychopharmacology & biological psychiatry. vol 15. issue 6. 1992-02-13. PMID:1722342. |
the effects of acute administration of sch 23390 (0.05 and 0.25 mg/kg s.c.), a dopamine d-1 receptor antagonist having also a moderate serotonin-s2 (5-ht-2) receptor blocking activity, and ritanserin (0.5 mg/kg), a specific 5-ht-2 antagonist, on dopamine (da) and serotonin (5-ht) turnover were investigated in dopaminergic (nucleus caudatus, nucleus accumbens, substantia nigra, a10 area) and serotonergic (nucleus raphe dorsalis and nucleus raphe medialis) rat brain nuclei. |
1992-02-13 |
2023-08-11 |
rat |