| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Karen A Moxon, Tina Kao, Jed S Shumsk. Role of cortical reorganization on the effect of 5-HT pharmacotherapy for spinal cord injury. Experimental neurology. vol 240. 2013-03-25. PMID:23159333. |
role of cortical reorganization on the effect of 5-ht pharmacotherapy for spinal cord injury. |
2013-03-25 |
2023-08-12 |
rat |
| August Heidland, Gholamreza Fazeli, André Klassen, Katarina Sebekova, Hans Hennemann, Udo Bahner, Biagio Di Iori. Neuromuscular electrostimulation techniques: historical aspects and current possibilities in treatment of pain and muscle waisting. Clinical nephrology. vol 79 Suppl 1. 2013-02-26. PMID:23249528. |
the pain relieving action of electricity was explained in particular by two main mechanisms: first, segmental inhibition of pain signals to the brain in the dorsal horn of the spinal cord and second, activation of the descending inhibitory pathway with enhanced release of endogenous opioids and other neurochemical compounds (serotonin, noradrenaline, gamma aminobutyric acid (gaba), acetylcholine and adenosine). |
2013-02-26 |
2023-08-12 |
Not clear |
| Du-Jie Xie, Daisuke Uta, Peng-Yu Feng, Masahito Wakita, Min-Chul Shin, Hidemasa Furue, Megumu Yoshimur. Identification of 5-HT receptor subtypes enhancing inhibitory transmission in the rat spinal dorsal horn in vitro. Molecular pain. vol 8. 2013-02-14. PMID:22906126. |
several electrophysiological studies have been performed to investigate the effects of 5-ht on excitatory transmission in substantia gelatinosa (sg) of the spinal cord. |
2013-02-14 |
2023-08-12 |
rat |
| Du-Jie Xie, Daisuke Uta, Peng-Yu Feng, Masahito Wakita, Min-Chul Shin, Hidemasa Furue, Megumu Yoshimur. Identification of 5-HT receptor subtypes enhancing inhibitory transmission in the rat spinal dorsal horn in vitro. Molecular pain. vol 8. 2013-02-14. PMID:22906126. |
in the present study, to understand the effects of 5-ht on the inhibitory synaptic transmission and to identify receptor subtypes, the blind whole cell recordings were performed from sg neurons of rat spinal cord slices. |
2013-02-14 |
2023-08-12 |
rat |
| B Godínez-Chaparro, F J López-Santillán, P Orduña, V Granados-Sot. Secondary mechanical allodynia and hyperalgesia depend on descending facilitation mediated by spinal 5-HT₄, 5-HT₆ and 5-HT₇ receptors. Neuroscience. vol 222. 2013-01-24. PMID:22796074. |
in addition, formalin increased the tissue content of 5-ht in the ipsilateral, but not contralateral, dorsal part of the spinal cord compared to control animals. |
2013-01-24 |
2023-08-12 |
rat |
| B Godínez-Chaparro, F J López-Santillán, P Orduña, V Granados-Sot. Secondary mechanical allodynia and hyperalgesia depend on descending facilitation mediated by spinal 5-HT₄, 5-HT₆ and 5-HT₇ receptors. Neuroscience. vol 222. 2013-01-24. PMID:22796074. |
administration of 5,7-dihydroxytriptamine (5,7-dht), a serotonergic neurotoxin, diminished tissue 5-ht content in the ipsilateral and contralateral dorsal parts of the spinal cord. |
2013-01-24 |
2023-08-12 |
rat |
| S Ohnami, A Kato, K Ogawa, S Shinohara, H Ono, M Tanab. Effects of milnacipran, a 5-HT and noradrenaline reuptake inhibitor, on C-fibre-evoked field potentials in spinal long-term potentiation and neuropathic pain. British journal of pharmacology. vol 167. issue 3. 2013-01-17. PMID:22537101. |
the analgesic action of 5-ht and noradrenaline reuptake inhibitors (snris) on nociceptive synaptic transmission in the spinal cord is poorly understood. |
2013-01-17 |
2023-08-12 |
Not clear |
| Zigor Aira, Itsaso Buesa, Mónica Gallego, Gontzal García del Caño, Nahia Mendiable, Janire Mingo, Diego Rada, Juan Bilbao, Manfred Zimmermann, Jon Jatsu Azku. Time-dependent cross talk between spinal serotonin 5-HT2A receptor and mGluR1 subserves spinal hyperexcitability and neuropathic pain after nerve injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 39. 2012-12-10. PMID:23015446. |
in the absence of snl, pharmacological stimulation of 5-ht(2a)r with tcb-2 both induced rapid bilateral upregulation of mglur1 expression in cytoplasmic and synaptic fractions of spinal cord homogenates, which was attenuated by pkc inhibitor chelerythrine, and enhanced evoked potentials during costimulation of mglur1 with 3,5-dhpg [(rs)-3,5-dihydroxyphenylglycine]. |
2012-12-10 |
2023-08-12 |
rat |
| Nagahisa Okamoto, Kota Sakamoto, Maki Yamad. Transient serotonin syndrome by concurrent use of electroconvulsive therapy and selective serotonin reuptake inhibitor: a case report and review of the literature. Case reports in psychiatry. vol 2012. 2012-12-06. PMID:23213590. |
the serotonin syndrome, which is characterized by psychiatric, autonomic nervous and neurological symptoms, is considered to be caused by excessive stimulation of the 5-ht1a and 5-ht2 receptors in the gray matter and spinal cord of the central nervous system, after the start of dosing or increase of the dose of a serotoninergic drug. |
2012-12-06 |
2023-08-12 |
Not clear |
| Andreas Husch, Gabrielle N Van Patten, Diana N Hong, Moira M Scaperotti, Nathan Cramer, Ronald M Harris-Warric. Spinal cord injury induces serotonin supersensitivity without increasing intrinsic excitability of mouse V2a interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 38. 2012-12-03. PMID:22993431. |
spinal cord injury induces serotonin supersensitivity without increasing intrinsic excitability of mouse v2a interneurons. |
2012-12-03 |
2023-08-12 |
mouse |
| Andreas Husch, Gabrielle N Van Patten, Diana N Hong, Moira M Scaperotti, Nathan Cramer, Ronald M Harris-Warric. Spinal cord injury induces serotonin supersensitivity without increasing intrinsic excitability of mouse V2a interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 38. 2012-12-03. PMID:22993431. |
using an adult mouse sci model, we analyzed the effects of complete spinal cord lesions on the intrinsic electrophysiological properties, excitability, and neuromodulatory responses to serotonin (5-ht) in mouse lumbar v2a spinal ins, which help regulate left-right alternation during locomotion. |
2012-12-03 |
2023-08-12 |
mouse |
| A Mickle, P Kannampalli, M Bruckert, A Miranda, B Banerjee, J N Sengupt. Pronociceptive effect of 5-HT(1A) receptor agonist on visceral pain involves spinal N-methyl-D-aspartate (NMDA) receptor. Neuroscience. vol 219. 2012-11-20. PMID:22626644. |
these results indicate that the 5-ht(1a) receptor agonist dpat produces pronociceptive effects, primarily via the activation of presynaptic 5-ht(1a) receptors in gabaergic neuron to restrict gaba release and thereby disinhibits the excitatory glutamatergic neurons in the spinal cord. |
2012-11-20 |
2023-08-12 |
rat |
| Mark J Airhart, Deborah H Lee, Tracy D Wilson, Barney E Miller, Merry N Miller, Richard G Skalko, Paul J Monac. Adverse effects of serotonin depletion in developing zebrafish. Neurotoxicology and teratology. vol 34. issue 1. 2012-10-15. PMID:21893190. |
immunohistological studies using a 5ht antibody confirmed that 5ht neurons in the brain and spinal cord were depleted of transmitter by 2 days post fertilization (dpf). |
2012-10-15 |
2023-08-12 |
zebrafish |
| Mark J Airhart, Deborah H Lee, Tracy D Wilson, Barney E Miller, Merry N Miller, Richard G Skalko, Paul J Monac. Adverse effects of serotonin depletion in developing zebrafish. Neurotoxicology and teratology. vol 34. issue 1. 2012-10-15. PMID:21893190. |
reverse transcriptase polymerase chain reaction (rt-pcr) was performed to determine the relative levels of the serotonin 1a receptor (5ht(1a)) transcript and the serotonin transporter (sert) transcript in the brain and spinal cord of control and treated embryos. |
2012-10-15 |
2023-08-12 |
zebrafish |
| Mark J Airhart, Deborah H Lee, Tracy D Wilson, Barney E Miller, Merry N Miller, Richard G Skalko, Paul J Monac. Adverse effects of serotonin depletion in developing zebrafish. Neurotoxicology and teratology. vol 34. issue 1. 2012-10-15. PMID:21893190. |
embryos treated with pcpa demonstrated a decrease in the concentration of 5ht(1a) transcript in both brain and spinal cord. |
2012-10-15 |
2023-08-12 |
zebrafish |
| Shelby Dietz, Andreas Husch, Ronald M Harris-Warric. A comparison of serotonin neuromodulation of mouse spinal V2a interneurons using perforated patch and whole cell recording techniques. Frontiers in cellular neuroscience. vol 6. 2012-10-15. PMID:23060747. |
we have previously used wcr to characterize the responses of the v2a class of chx10-expressing neurons to serotonin (5-ht) in the neonatal mouse spinal cord (zhong et al., 2010). |
2012-10-15 |
2023-08-12 |
mouse |
| Shelby Dietz, Andreas Husch, Ronald M Harris-Warric. A comparison of serotonin neuromodulation of mouse spinal V2a interneurons using perforated patch and whole cell recording techniques. Frontiers in cellular neuroscience. vol 6. 2012-10-15. PMID:23060747. |
here we directly compare multiple aspects of the responses to 5-ht using wcr and ppr in chx10-ecfp neurons in spinal cord slices from 2 to 4 day old mice. |
2012-10-15 |
2023-08-12 |
mouse |
| Masafumi Kimura, Hideaki Obata, Shigeru Sait. Antihypersensitivity effects of tramadol hydrochloride in a rat model of postoperative pain. Anesthesia and analgesia. vol 115. issue 2. 2012-10-09. PMID:22575568. |
the effect of tramadol on na and 5-ht concentrations in the spinal cord, however, have not been assessed. |
2012-10-09 |
2023-08-12 |
rat |
| Masafumi Kimura, Hideaki Obata, Shigeru Sait. Antihypersensitivity effects of tramadol hydrochloride in a rat model of postoperative pain. Anesthesia and analgesia. vol 115. issue 2. 2012-10-09. PMID:22575568. |
we also evaluated the increase in na and 5-ht levels in the spinal cord after tramadol injection using in vivo microdialysis. |
2012-10-09 |
2023-08-12 |
rat |
| T Kumazawa, K Adachi, K Ando, S Od. Enhancement of 5-hydroxytryptamine turnover in descending serotonergic neurons of shambling mutant mice. Neurochemistry international. vol 11. issue 3. 2012-10-02. PMID:20501172. |
5-ht and 5-hiaa concentrations in the brain stem and spinal cord of the shambling mice were significantly higher than those of the normal mice. |
2012-10-02 |
2023-08-12 |
mouse |