| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cristián Gutiérrez-Ibáñez, Douglas R Wyli. Investigation of central pattern generators in the spinal cord of chicken embryos. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. 2024-03-24. PMID:38521869. |
we found that in response to n-methyl-d-aspartate (nmda) or a combination of nmda and serotonin (5-ht), the intact chicken spinal cord produced rhythmic outputs that were synchronous both bilaterally and between the wing and leg segments. |
2024-03-24 |
2024-03-26 |
chicken |
| Xiahai Zheng, Jing Lin, Zhenzhen Wang, Zhenming Zeng, Haoxiong Che. Research of the analgesic effects and central nervous system impact of electroacupuncture therapy in rats with knee osteoarthritis. Heliyon. vol 10. issue 1. 2024-01-16. PMID:38226224. |
dopamine (da), norepinephrine (ne), 5-hydroxytryptamine (5-ht), β-endorphin (β-ep), and leucine-enkephalin (l-enk) were detected in the midbrain and spinal cord of lumbar enlargement. |
2024-01-16 |
2024-01-18 |
rat |
| Xiahai Zheng, Jing Lin, Zhenzhen Wang, Zhenming Zeng, Haoxiong Che. Research of the analgesic effects and central nervous system impact of electroacupuncture therapy in rats with knee osteoarthritis. Heliyon. vol 10. issue 1. 2024-01-16. PMID:38226224. |
the incubation period of thermal pain and foot contraction was decreased in the koa group versus blank group, the lequesne mg score was increased, da, ne, 5-ht, β-ep, and l-enk in the midbrain and spinal cord were increased, and synovial tissue il-1β protein expression was increased ( |
2024-01-16 |
2024-01-18 |
rat |
| Yu-Long Zhao, Jia-Liang Xu, Hui-Yuan Yi, Sani Sa'idu Baba, Yi-Xiao Guo, Xue-Mei Hou, Xiao-Cui Yuan, Xu-Hui Li, Yu-Ying Wang, Ling-Li Liang, Fu-Quan Hu. Activation of 5-HT Neuropharmacology. 2023-12-31. PMID:38160874. |
activation of 5-ht the ventrolateral orbital cortex (vlo) is identified as an integral component of the endogenous analgesic system comprising a spinal cord - thalamic nucleus submedius - vlo - periaqueductal gray (pag) - spinal cord loop. |
2023-12-31 |
2024-01-05 |
Not clear |
| Dmitrii S Traktirov, Ilya R Nazarov, Valeria S Artemova, Raul R Gainetdinov, Nina S Pestereva, Marina N Karpenk. Alterations in Serotonin Neurotransmission in Hyperdopaminergic Rats Lacking the Dopamine Transporter. Biomedicines. vol 11. issue 11. 2023-11-25. PMID:38001881. |
furthermore, significant changes were observed in the production of mrna of enzymes of monoamine metabolism, as well as to a notable alteration in the tissue level of serotonin, most clearly manifested in the cerebellum and the spinal cord. |
2023-11-25 |
2023-11-28 |
rat |
| Nathan Cramer, Yadong Ji, Maureen A Kane, Nageswara R Pilli, Alberto Castro, Luca Posa, Gabrielle Van Patten, Radi Masri, Asaf Kelle. Elevated serotonin in mouse spinal dorsal horn is pronociceptive. eNeuro. 2023-11-09. PMID:37945351. |
these findings suggest that serotonin release in the spinal cord is pronociceptive and that an increase in sustained serotonin signaling, rather than phasic or event driven increases, potentiate nociception in models of chronic pain. |
2023-11-09 |
2023-11-20 |
mouse |
| Danielle Diniz Aguiar, Júlia Alvarenga Petrocchi, Grazielle Caroline da Silva, Virgínia Soares Lemos, Marina Gomes Miranda E Castor, Andrea de Castro Perez, Igor Dimitri Gama Duarte, Thiago Roberto Lima Romer. Participation of the cannabinoid system and the NO/cGMP/K Neuroscience letters. 2023-10-28. PMID:37898181. |
participation of the cannabinoid system and the no/cgmp/k it has already been shown that serotonin can release endocannabinoids at the spinal cord level, culminating in inhibition of the dorsal horn. |
2023-10-28 |
2023-11-08 |
Not clear |
| Yoshiharu Takahashi, Takumi Kajitani, Toshiki Endo, Atsushi Nakayashiki, Tomoo Inoue, Kuniyasu Niizuma, Teiji Tominag. Intravenous Administration of Human Muse Cells Ameliorates Deficits in a Rat Model of Subacute Spinal Cord Injury. International journal of molecular sciences. vol 24. issue 19. 2023-10-14. PMID:37834052. |
furthermore, larger numbers of descending 5-ht fibers were preserved in the distal spinal cord. |
2023-10-14 |
2023-10-15 |
human |
| Inès Khsime, Marie Boulain, Abderrahman Fettah, Abdeslam Chagraoui, Gilles Courtand, Philippe De Deurwaerdère, Laurent Juvin, Grégory Barrièr. Limiting Monoamines Degradation Increases L-DOPA Pro-Locomotor Action in Newborn Rats. International journal of molecular sciences. vol 24. issue 19. 2023-10-14. PMID:37834195. |
tissue measurements of monoamines (dopamine, noradrenaline, serotonin and some of their metabolites) in the cervical and lumbar spinal cord confirmed the regional efficacy of each inhibitor toward their respective enzyme. |
2023-10-14 |
2023-10-15 |
rat |
| Mitchell T Ringuet, Ada Koo, Sebastian G B Furness, Stuart J McDougall, John B Furnes. Sites and mechanisms of action of colokinetics at dopamine, ghrelin and serotonin receptors in the rodent lumbosacral defecation centre. The Journal of physiology. 2023-09-29. PMID:37772438. |
whole cell electrophysiology in adult mice spinal cord revealed that dopamine, serotonin, α-methylserotonin and capromorelin each caused inward, excitatory currents in overlapping populations of lumbosacral pgns. |
2023-09-29 |
2023-10-07 |
mouse |
| Mitchell T Ringuet, Ada Koo, Sebastian G B Furness, Stuart J McDougall, John B Furnes. Sites and mechanisms of action of colokinetics at dopamine, ghrelin and serotonin receptors in the rodent lumbosacral defecation centre. The Journal of physiology. 2023-09-29. PMID:37772438. |
key points: dopamine, 5-hydroxytryptamine (5-ht, serotonin) and ghrelin (ghsr) receptor agonists increase colorectal motility and have been postulated to act at receptors on parasympathetic preganglionic neurons (pgns) in the lumbosacral spinal cord. |
2023-09-29 |
2023-10-07 |
mouse |
| Mitchell T Ringuet, Ada Koo, Sebastian G B Furness, Stuart J McDougall, John B Furnes. Sites and mechanisms of action of colokinetics at dopamine, ghrelin and serotonin receptors in the rodent lumbosacral defecation centre. The Journal of physiology. 2023-09-29. PMID:37772438. |
we aimed to determine which neurons in the lumbosacral spinal cord express dopamine, serotonin and ghsr receptors, their neural inputs, and whether agonists at these receptors excite them. |
2023-09-29 |
2023-10-07 |
mouse |
| Nathan Cramer, Yadong Ji, Maureen Kane, Nageswara Pilli, Luca Posa, Gabrielle Van Patten, Radi Masri, Asaf Kelle. Elevated serotonin in mouse spinal dorsal horn is pronociceptive. bioRxiv : the preprint server for biology. 2023-08-30. PMID:37645759. |
these findings suggest that serotonin release in the spinal cord is pronociceptive and that an increase is sustained serotonin signaling, rather than phasic or event driven increases, potentiate nociception in models of chronic pain. |
2023-08-30 |
2023-09-07 |
mouse |
| Emily J Reedich, Landon T Genry, Preston R Steele, Elvia Mena Avila, Lisa Dowaliby, Alexander Drobyshevsky, Marin Manuel, Katharina A Quinla. Spinal motoneurons respond aberrantly to serotonin in a rabbit model of cerebral palsy. The Journal of physiology. 2023-08-16. PMID:37584461. |
rabbits that experience hypoxic-ischaemic (hi) injury in utero (at 70%-83% gestation) are born with muscle stiffness, hyperreflexia and, as recently discovered, increased 5-ht in the spinal cord. |
2023-08-16 |
2023-09-07 |
rabbit |
| Shingo Nakamura, Shuji Komatsu, Toshihiko Yamada, Hiromi Kitahara, Tatsuo Yamamot. Oral morphine induces spinal 5-hydroxytryptamine (5-HT) release using an opioid receptor-independent mechanism. Pharmacology research & perspectives. vol 11. issue 4. 2023-07-24. PMID:37488088. |
oral morphine, but not oral oxycodone, increased 5-ht release at the spinal cord to approximately 4000% of the baseline value. |
2023-07-24 |
2023-08-14 |
rat |
| Aruna Sharma, Dafin F Muresanu, Z Ryan Tian, Ala Nozari, José Vicente Lafuente, Anca D Buzoianu, Per-Ove Sjöquist, Lianyuan Feng, Lars Wiklund, Hari Shanker Sharm. Co-Administration of Nanowired Monoclonal Antibodies to Inducible Nitric Oxide Synthase and Tumor Necrosis Factor Alpha Together with Antioxidant H-290/51 Reduces SiO Advances in neurobiology. vol 32. 2023-07-22. PMID:37480462. |
spinal cord injury is well known to alter serotonin (5-hydroxytryptamine) metabolism and induce oxidative stress including upregulation of nitric oxide synthase and tumor necrosis factor alpha. |
2023-07-22 |
2023-08-14 |
Not clear |
| Miriam Aceves, Ashley Tucker, Joseph Chen, Katie Vo, Joshua Moses, Prakruthi Amar Kumar, Hannah Thomas, Diego Miranda, Gabrielle Dampf, Valerie Dietz, Matthew Chang, Aleena Lukose, Julius Jang, Sneha Nadella, Tucker Gillespie, Christian Trevino, Andrew Buxton, Anna L Pritchard, Peyton Green, Dylan A McCreedy, Jennifer N Duli. Developmental stage of transplanted neural progenitor cells influences anatomical and functional outcomes after spinal cord injury in mice. Communications biology. vol 6. issue 1. 2023-05-19. PMID:37208439. |
earlier-stage grafts exhibited greater axon outgrowth, enrichment for ventral spinal cord interneurons and group-z spinal interneurons, and enhanced host 5-ht |
2023-05-19 |
2023-08-14 |
mouse |
| Alexandria B Marciante, Gordon S Mitchel. Increased spinal adenosine impairs phrenic long-term facilitation in aging rats. Journal of applied physiology (Bethesda, Md. : 1985). 2023-05-11. PMID:37167263. |
since spinal a2a receptor inhibition enhances maih-induced pltf, serotonin dominates, and adenosine constrains maih-induced plasticity in the daily rest phase, we hypothesized elevated basal adenosine levels in the ventral cervical spinal cord of aged rats shifts this balance, undermining maih-induced pltf. |
2023-05-11 |
2023-08-14 |
rat |
| Shun Hao, Wantong Shi, Weiqi Liu, Qi-Yu Chen, Min Zhu. Multiple modulatory roles of serotonin in chronic pain and injury-related anxiety. Frontiers in synaptic neuroscience. vol 15. 2023-05-05. PMID:37143481. |
5-ht exerts multiple modulations of synaptic transmission and plasticity in the acc and the spinal cord, including activation, inhibition, and biphasic actions. |
2023-05-05 |
2023-08-14 |
Not clear |
| Akihito Takeda, Mao Fujita, Kengo Funakosh. Distribution of 5HT Receptors During the Regeneration Process After Spinal Cord Transection in Goldfish. Journal of chemical neuroanatomy. 2023-04-29. PMID:37119932. |
distribution of 5ht receptors during the regeneration process after spinal cord transection in goldfish. |
2023-04-29 |
2023-08-14 |
Not clear |