| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kazuhiro Horii, Tomoya Sawamura, Natsufu Yuki, Takahiko Shiina, Yasutake Shimiz. Sex differences in the central regulation of colorectal motility in response to noxious stimuli. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi. vol 59. 2023-04-26. PMID:37100618. |
these monoaminergic neurons release serotonin and dopamine into the lumbosacral spinal cord, resulting in the increment of colorectal motility. |
2023-04-26 |
2023-08-14 |
rat |
| Kinga Krzysztoforska, Agnieszka Piechal, Ewa Wojnar, Kamilla Blecharz-Klin, Justyna Pyrzanowska, Ilona Joniec-Maciejak, Jan Krzysztoforski, Ewa Widy-Tyszkiewic. Protocatechuic Acid Prevents Some of the Memory-Related Behavioural and Neurotransmitter Changes in a Pyrithiamine-Induced Thiamine Deficiency Model of Wernicke-Korsakoff Syndrome in Rats. Nutrients. vol 15. issue 3. 2023-02-11. PMID:36771332. |
compared to the control group, rats with wks showed reduced serotonin levels in the prefrontal cortex and changes in dopamine and/or norepinephrine metabolites in the prefrontal cortex, medulla oblongata and spinal cord. |
2023-02-11 |
2023-08-14 |
rat |
| Chao Zhang, Xin Meng, Long Chen, Xiang Zhang, Hulbtorn Hans, Liqun Re. Changes in 5-HT1F receptor expression in rats with spasticity following spinal cord injury. Neuroscience letters. vol 793. 2022-12-06. PMID:36471527. |
little is known about the distribution of the serotonin 1f receptor (5-ht1fr) in the spinal cord, especially in relation to the spasticity caused by sci. |
2022-12-06 |
2023-08-14 |
rat |
| Wen-Qiang Ge, Ou-Yang Zhan-Mu, Chao Chen, Hong Zhang, Xiao-Yu Wang, Xin Liu, Li Li, Yu-Ye Lan, Chen-Nan Li, Jia-Can Sun, Run-Lin Shi, Zi-Yue Dou, Hui-Lin Pan, Hong-Ping Li, Xiang-Hong Jing, Man L. Electroacupuncture reduces chronic itch Frontiers in pharmacology. vol 13. 2022-09-22. PMID:36133809. |
ea reversed the increased expression of cb1 receptors in the vlpag and decreased the concentration of 5-hydroxytryptamine (5-ht) in the medulla oblongata and the expression of gastrin-releasing peptide receptors (grpr) in the cervical spinal cord. |
2022-09-22 |
2023-08-14 |
mouse |
| Wen-Qiang Ge, Ou-Yang Zhan-Mu, Chao Chen, Hong Zhang, Xiao-Yu Wang, Xin Liu, Li Li, Yu-Ye Lan, Chen-Nan Li, Jia-Can Sun, Run-Lin Shi, Zi-Yue Dou, Hui-Lin Pan, Hong-Ping Li, Xiang-Hong Jing, Man L. Electroacupuncture reduces chronic itch Frontiers in pharmacology. vol 13. 2022-09-22. PMID:36133809. |
our findings suggest that ea treatment reduces chronic itch by activation of cb1 receptors on glutamatergic neurons and inhibition of cb1 receptors on gabaergic neurons in the vlpag, thereby inhibiting the 5-ht release from the medulla oblongata to grpr-expressing neurons in the spinal cord. |
2022-09-22 |
2023-08-14 |
mouse |
| Kanza M Khan, Gabrielle Bierlein-De La Rosa, Natalie Biggerstaff, Govindhasamy Pushpavathi Selvakumar, Ruixiang Wang, Suzanne Mason, Michael E Dailey, Catherine A Marcinkiewc. Adolescent ethanol drinking promotes hyperalgesia, neuroinflammation and serotonergic deficits in mice that persist into adulthood. Brain, behavior, and immunity. 2022-07-30. PMID:35907582. |
5-ht expression was also reduced in the thalamus, anterior cingulate cortex (acc) and amygdala as well as the lumbar dorsal horn of the spinal cord. |
2022-07-30 |
2023-08-14 |
mouse |
| Franck Aby, Louis-Etienne Lorenzo, Zoé Grivet, Rabia Bouali-Benazzouz, Hugo Martin, Stéphane Valerio, Sara Whitestone, Dominique Isabel, Walid Idi, Otmane Bouchatta, Philippe De Deurwaerdere, Antoine G Godin, Cyril Herry, Xavier Fioramonti, Marc Landry, Yves De Koninck, Pascal Fossa. Switch of serotonergic descending inhibition into facilitation by a spinal chloride imbalance in neuropathic pain. Science advances. vol 8. issue 30. 2022-07-27. PMID:35895817. |
we used an optogenetic approach to manipulate serotonin (5-ht) neurons of the nucleus raphe magnus that project to the dorsal horn of the spinal cord. |
2022-07-27 |
2023-08-14 |
mouse |
| Justin J Kavanagh, Janet L Taylo. Voluntary activation of muscle in humans: does serotonergic neuromodulation matter? The Journal of physiology. 2022-07-22. PMID:35864781. |
the release of serotonin (5-ht) into the spinal cord is linked to the level of motor activity being performed, where 5-ht can increase the discharge rate of motoneurones via excitatory 5-ht receptors on the soma and dendrites. |
2022-07-22 |
2023-08-14 |
human |
| Marlene Storm Andersen, Dilârâ Bedriye Güler, Jonas Larsen, Karen Kalhøj Rich, Åsa Fex Svenningsen, Mengliang Zhan. The Development of Hindlimb Postural Asymmetry Induced by Focal Traumatic Brain Injury Is Not Related to Serotonin 2A/C Receptor Expression in the Spinal Cord. International journal of molecular sciences. vol 23. issue 10. 2022-05-28. PMID:35628167. |
the development of hindlimb postural asymmetry induced by focal traumatic brain injury is not related to serotonin 2a/c receptor expression in the spinal cord. |
2022-05-28 |
2023-08-13 |
rat |
| Marlene Storm Andersen, Dilârâ Bedriye Güler, Jonas Larsen, Karen Kalhøj Rich, Åsa Fex Svenningsen, Mengliang Zhan. The Development of Hindlimb Postural Asymmetry Induced by Focal Traumatic Brain Injury Is Not Related to Serotonin 2A/C Receptor Expression in the Spinal Cord. International journal of molecular sciences. vol 23. issue 10. 2022-05-28. PMID:35628167. |
this study, which was conducted on rats, investigated the development of limb postural changes and their relationship to the expression of serotonin (5-ht) 2a and 2c receptors in the spinal cord in the 4 weeks after focal traumatic brain injury (tbi) to the right hindlimb sensorimotor cortex. |
2022-05-28 |
2023-08-13 |
rat |
| Shanshan Li, Suhong Zhao, Yi Guo, Yuanzhen Yang, Jin Huang, Jiaqi Wang, Shanshan Lu, Bin Wang, Chao Chai, Zhifang Xu, Yenlie Chi. Clinical Efficacy and Potential Mechanisms of Acupoint Stimulation Combined With Chemotherapy in Combating Cancer: A Review and Prospects. Frontiers in oncology. vol 12. 2022-05-13. PMID:35547876. |
it was found that acupoint stimulation attenuated cipn and gi by modulating the 5-hydroxytryptamine system in dorsal root ganglia, the dorsal horn of the spinal cord, and the duodenum by reducing oxidative stress and neuroinflammation. |
2022-05-13 |
2023-08-13 |
Not clear |
| Qingchao Qiu, Dylan Kissane, Donald Kuhn, Jason Mateik. Central nervous system 5-HT plays a role in ventilatory and arousal responses to hypoxia and hypercapnia in spinal cord injured mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35552044. |
central nervous system 5-ht plays a role in ventilatory and arousal responses to hypoxia and hypercapnia in spinal cord injured mice. |
2022-05-13 |
2023-08-13 |
mouse |
| Qingchao Qiu, Dylan Kissane, Donald Kuhn, Jason Mateik. Central nervous system 5-HT plays a role in ventilatory and arousal responses to hypoxia and hypercapnia in spinal cord injured mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35552044. |
the present investigation was designed to explore the impact of serotonin (5ht) on the arousal and ventilatory response to hypercapnia and hypoxia following spinal cord injury (sci) in mice. |
2022-05-13 |
2023-08-13 |
mouse |
| Laura E Mendenhall, Chase E Taylor, Lance A Johnson, Warren J Alilia. Humanized ApoE4 Female Mice Exhibit a More Robust Hypoxic Ventilatory Response Than Female E3 Mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556350. |
to further understand this distinction, future experiments will examine differences in levels of brainstem and spinal cord serotonin expression between apoe3 and e4 males and females, as well as plasticity following injury in areas high in apoe expression. |
2022-05-13 |
2023-08-13 |
mouse |
| Afaf Bajjig, Florence Cayetanot, J Andrew Taylor, Laurence Bodineau, Isabelle Vivodtze. Serotonin 1A Receptor Pharmacotherapy and Neuroplasticity in Spinal Cord Injury. Pharmaceuticals (Basel, Switzerland). vol 15. issue 4. 2022-04-23. PMID:35455457. |
serotonin 1a receptor pharmacotherapy and neuroplasticity in spinal cord injury. |
2022-04-23 |
2023-08-13 |
Not clear |
| Afaf Bajjig, Florence Cayetanot, J Andrew Taylor, Laurence Bodineau, Isabelle Vivodtze. Serotonin 1A Receptor Pharmacotherapy and Neuroplasticity in Spinal Cord Injury. Pharmaceuticals (Basel, Switzerland). vol 15. issue 4. 2022-04-23. PMID:35455457. |
although no current treatments exist to restore motor function in spinal cord injury (sci), serotoninergic (5-ht) 1a receptor agonists appear as pharmacologic neuromodulators that could be important players in inducing functional improvements by increasing the activation of spared motoneurons. |
2022-04-23 |
2023-08-13 |
Not clear |
| Xiao Cui Yuan, Yu-Ying Wang, Li-Xia Tian, Xiang-Ji Yan, Yi-Xiao Guo, Yu-Long Zhao, Sani Sa'idu Baba, Hong Jia, Hui-Sheng Wang, Man Li, Fu-Quan Hu. Spinal 5-HT2A Receptor is Involved in Electroacupuncture Inhibition of Chronic Pain. Molecular pain. 2022-03-04. PMID:35240891. |
however, it is still unclear which among the 5-ht receptor subtype is involved in ea evoked 5-ht mediated inhibition of chronic pain in the dorsal spinal cord. |
2022-03-04 |
2023-08-13 |
mouse |
| Shuangyan Wang, Pei Wang, Ruian Yin, Ming Xiao, Yongjie Zhang, Jan D Reinhardt, Hongxing Wang, Guangxu X. Combination of repetitive transcranial magnetic stimulation and treadmill training reduces hyperreflexia by rebalancing motoneuron excitability in rats after spinal cord contusion. Neuroscience letters. 2022-02-20. PMID:35183693. |
pathological analyses demonstrated that the combined treatment facilitated the growth of serotonergic axons around the lesion site, and the upregulation of 5-hydroxytryptamine, potassium-chloride cotransporter-2, and glutamic acid decarboxylases 67 in the lumbar spinal cord distal to the injury site. |
2022-02-20 |
2023-08-13 |
rat |
| Hanyi Fang, Samantha Rossano, Xingxing Wang, Nabeel Nabulsi, Brian Kelley, Krista Fowles, Jim Ropchan, Stephen M Strittmatter, Richard E Carson, Yiyun Huan. Translational PET Imaging of Spinal Cord Injury with the Serotonin Transporter Tracer [ Molecular imaging and biology. 2022-01-12. PMID:35020138. |
translational pet imaging of spinal cord injury with the serotonin transporter tracer [ the descending raphespinal serotonin (5-ht) system contributes to neural activities required for locomotion. |
2022-01-12 |
2023-08-13 |
Not clear |
| Mathilde Baudat, Anne R de Kort, Daniel L A van den Hove, Elbert A J Jooste. Early-life exposure to selective serotonin reuptake inhibitors: long-term effects on pain and affective comorbidities. The European journal of neuroscience. 2021-11-29. PMID:34841582. |
we conclude that early-life selective serotonin reuptake inhibitor exposure affects the maturation of prefrontal cortex and amygdala circuits and thereby enhances their anti-nociceptive inputs in the spinal cord. |
2021-11-29 |
2023-08-13 |
Not clear |