| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takato Nikaido, Chikashi Maruyama, Minako Hamanaka, Chiharu Yamaguchi, Yukiko Fujimaru, Yutaka Nakanishi, Toshiki Asano, Akiko Takaok. Ethenzamide Exerts Analgesic Effect at the Spinal Cord via Multiple Mechanisms of Action Including the 5HT Biological & pharmaceutical bulletin. vol 43. issue 5. 2021-01-15. PMID:32147623. |
ethenzamide exerts analgesic effect at the spinal cord via multiple mechanisms of action including the 5ht ethenzamide (etz), an antipyretic analgesic categorized as a non-steroidal anti-inflammatory drug (nsaid), is widely used as an otc drug in combination with other nsaids. |
2021-01-15 |
2023-08-13 |
rat |
| Li-Qun Ren, Meng Chen, Hans Hultborn, Sen Guo, Yifan Zhang, Mengliang Zhan. Heterogenic Distribution of Aromatic L-Amino Acid Decarboxylase Neurons in the Rat Spinal Cord. Frontiers in integrative neuroscience. vol 11. 2020-10-01. PMID:29225571. |
aromatic l-amino acid decarboxylase (aadc) is an essential enzyme in the synthesis of serotonin, dopamine, and certain trace amines and is present in a variety of organs including the brain and spinal cord. |
2020-10-01 |
2023-08-13 |
rat |
| Kenichi Serizawa, Haruna Tomizawa-Shinohara, Hideyuki Yasuno, Kenji Yogo, Yoshihiro Matsumot. Anti-IL-6 Receptor Antibody Inhibits Spontaneous Pain at the Pre-onset of Experimental Autoimmune Encephalomyelitis in Mice. Frontiers in neurology. vol 10. 2020-10-01. PMID:31024434. |
measurement of 5-ht in the spinal cord and functional imaging of the periaqueductal gray (pag) were also performed. |
2020-10-01 |
2023-08-13 |
mouse |
| Yun Wu, Huijun Chen, Zui Tan, Dan Li, Chuan Lian. Therapeutic effects of Erbin inhibitor on spinal cord contusion in mice. American journal of translational research. vol 11. issue 4. 2020-10-01. PMID:31105863. |
the contents of 5-hydroxytryptamine (5-ht) and reactive oxygen species (ros) in the brain and spinal cord tissues were measured using elisa. |
2020-10-01 |
2023-08-13 |
mouse |
| Ahmed B Bayoumi, Oyku Ikizgul, Ceren Nur Karaali, Selma Bozkurt, Deniz Konya, Zafer Orkun Tokta. Antidepressants in Spine Surgery: A Systematic Review to Determine Benefits and Risks. Asian spine journal. vol 13. issue 6. 2020-10-01. PMID:31422644. |
the preoperative treatment of preexisting psychiatric diseases, such as anxiety and depression, can improve outcomes for patients with spinal cord injury-related disabilities; however, a preoperative platelet function assay is advocated prior to major spine surgical procedures to protect against significant intraoperative blood loss, as serotonergic antidepressants (e.g., selective serotonin reuptake inhibitors) and bupropion can increase the likelihood of bleeding intraoperatively due to drug-induced platelet dysfunction. |
2020-10-01 |
2023-08-13 |
Not clear |
| Mengliang Zhan. Two-step production of monoamines in monoenzymatic cells in the spinal cord: a different control strategy of neurotransmitter supply? Neural regeneration research. vol 11. issue 12. 2020-09-30. PMID:28197177. |
in this review, i will present evidence for a possible pathway for two-step synthesis of dopamine and serotonin in the spinal cord. |
2020-09-30 |
2023-08-13 |
Not clear |
| Mengliang Zhan. Two-step production of monoamines in monoenzymatic cells in the spinal cord: a different control strategy of neurotransmitter supply? Neural regeneration research. vol 11. issue 12. 2020-09-30. PMID:28197177. |
prompted by the above evidence, i hypothesize that dopamine and serotonin could be synthesized sequentially in two monoenzymatic cells in the spinal cord |
2020-09-30 |
2023-08-13 |
Not clear |
| Francesca Cisani, Alessandra Roggeri, Guendalina Olivero, Beatrice Garrone, Serena Tongiani, Francesco Paolo Di Giorgio, Anna Pittalug. Acute Low Dose of Trazodone Recovers Glutamate Release Efficiency and mGlu2/3 Autoreceptor Impairments in the Spinal Cord of Rats Suffering From Chronic Sciatic Ligation. Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32765286. |
we investigated whether chronic sciatic ligation modifies the glutamate release in spinal cord nerve endings (synaptosomes) as well as the expression and the function of presynaptic release-regulating mglu2/3 autoreceptors and 5-ht |
2020-09-28 |
2023-08-13 |
rat |
| Epiphani C Simmons, Natalie E Scholpa, Kristan H Cleveland, Rick G Schnellman. 5-hydroxytryptamine 1F Receptor Agonist Induces Mitochondrial Biogenesis and Promotes Recovery from Spinal Cord Injury. The Journal of pharmacology and experimental therapeutics. vol 372. issue 2. 2020-07-14. PMID:31776207. |
5-hydroxytryptamine 1f receptor agonist induces mitochondrial biogenesis and promotes recovery from spinal cord injury. |
2020-07-14 |
2023-08-13 |
Not clear |
| Elena Kondratskaya, Oleksandr Ievglevskyi, Mark Züchner, Athina Samara, Joel C Glover, Jean-Luc Boullan. Locomotor central pattern generator excitability states and serotonin sensitivity after spontaneous recovery from a neonatal lumbar spinal cord injury. Brain research. vol 1708. 2020-06-15. PMID:30521786. |
locomotor central pattern generator excitability states and serotonin sensitivity after spontaneous recovery from a neonatal lumbar spinal cord injury. |
2020-06-15 |
2023-08-13 |
mouse |
| Rita Bardon. Serotonergic Modulation of Nociceptive Circuits in Spinal Cord Dorsal Horn. Current neuropharmacology. vol 17. issue 12. 2020-04-01. PMID:31573888. |
despite the extensive number of studies performed in the last 50 years, aimed at describing the role of serotonin and its receptors in pain modulation at the spinal cord level, several aspects are still not entirely understood. |
2020-04-01 |
2023-08-13 |
Not clear |
| Wei Wang, Xiongxiong Zhong, Yongyong Li, Ruixian Guo, Sujuan Du, Lili Wen, Yanlu Ying, Tao Yang, Xu-Hong We. Rostral ventromedial medulla-mediated descending facilitation following P2X7 receptor activation is involved in the development of chronic post-operative pain. Journal of neurochemistry. vol 149. issue 6. 2020-03-13. PMID:30570747. |
importantly, bbg injected into the rvm also decreased the activation of microglia and the level of 5-ht in the lumbar 3 (l3) spinal cord. |
2020-03-13 |
2023-08-13 |
rat |
| Jacob E Montgomery, Sarah Wahlstrom-Helgren, Timothy D Wiggin, Brittany M Corwin, Christina Lillesaar, Mark A Masin. Intraspinal serotonergic signaling suppresses locomotor activity in larval zebrafish. Developmental neurobiology. 2020-03-06. PMID:29923318. |
serotonin (5ht) is a modulator of many vital processes in the spinal cord (sc), such as production of locomotion. |
2020-03-06 |
2023-08-13 |
zebrafish |
| Florence Evelyne Perrin, Harun Najib Noristan. Serotonergic mechanisms in spinal cord injury. Experimental neurology. vol 318. 2020-03-02. PMID:31085200. |
serotonin (5-ht) neurotransmission in the spinal cord is critical for modulating sensory, motor, and autonomic functions. |
2020-03-02 |
2023-08-13 |
Not clear |
| Florence Evelyne Perrin, Harun Najib Noristan. Serotonergic mechanisms in spinal cord injury. Experimental neurology. vol 318. 2020-03-02. PMID:31085200. |
here we present a brief description of 5-ht discovery, 5-ht innervation of the cns, and physiological functions of 5-ht in the spinal cord, including its role in controlling bladder function. |
2020-03-02 |
2023-08-13 |
Not clear |
| Ana M Lucas-Osma, Yaqing Li, Katie Murray, Shihao Lin, Sophie Black, Marilee J Stephens, Andrew H Ahn, C J Heckman, Keith K Fenrich, Karim Fouad, David J Bennet. 5-HT Journal of neurophysiology. vol 121. issue 5. 2020-02-26. PMID:30625007. |
5-ht the monosynaptic stretch reflex (msr) plays an important role in feedback control of movement and posture but can also lead to unstable oscillations associated with tremor and clonus, especially when increased with spinal cord injury (sci). |
2020-02-26 |
2023-08-13 |
rat |
| Ana M Lucas-Osma, Yaqing Li, Katie Murray, Shihao Lin, Sophie Black, Marilee J Stephens, Andrew H Ahn, C J Heckman, Keith K Fenrich, Karim Fouad, David J Bennet. 5-HT Journal of neurophysiology. vol 121. issue 5. 2020-02-26. PMID:30625007. |
to control the msr and clonus after sci, we examined how serotonin regulates the msr in the sacrocaudal spinal cord of rats with and without a chronic spinal transection. |
2020-02-26 |
2023-08-13 |
rat |
| Lauren J Donovan, William C Spencer, Meagan M Kitt, Brent A Eastman, Katherine J Lobur, Kexin Jiao, Jerry Silver, Evan S Deneri. Lmx1b is required at multiple stages to build expansive serotonergic axon architectures. eLife. vol 8. 2020-02-03. PMID:31355748. |
we report that lim homeodomain factor 1b (lmx1b)-deficient 5-ht neurons fail to generate axonal projections to the forebrain and spinal cord. |
2020-02-03 |
2023-08-13 |
mouse |
| Minoru Miyazato, Asuka Ashikar. [Therapeutic new targets for stress urinary incontinence in the central nervous system]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 155. issue 1. 2020-01-24. PMID:31902839. |
therapeutic targets include adrenergic and serotonergic (5-ht) receptors in the spinal cord, which stimulate pudendal nerve innervating the external urethral sphincter and/or sympathetic nerve innervating urethral smooth muscle. |
2020-01-24 |
2023-08-13 |
rat |
| Jalesh N Panicke. The Onuf's nucleus, serotonin and spinal cord injury. BJU international. vol 123. issue 4. 2019-12-02. PMID:30499628. |
the onuf's nucleus, serotonin and spinal cord injury. |
2019-12-02 |
2023-08-13 |
Not clear |