| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anne Jaerve, Nora Schiwy, Christine Schmitz, Hans W Muelle. Differential effect of aging on axon sprouting and regenerative growth in spinal cord injury. Experimental neurology. vol 231. issue 2. 2011-11-02. PMID:21806987. |
we found that aging significantly reduces spontaneous axon sprouting of corticospinal (cst), serotonergic (5-ht) raphespinal and catecholaminergic (th) coerulospinal tracts in distinct regions of the spinal cord rostral to the lesion. |
2011-11-02 |
2023-08-12 |
rat |
| Zhiyang Song, Björn A Meyerson, Bengt Linderot. Spinal 5-HT receptors that contribute to the pain-relieving effects of spinal cord stimulation in a rat model of neuropathy. Pain. vol 152. issue 7. 2011-10-13. PMID:21514998. |
spinal 5-ht receptors that contribute to the pain-relieving effects of spinal cord stimulation in a rat model of neuropathy. |
2011-10-13 |
2023-08-12 |
rat |
| Jian-jun Chen, Qin Yang, Xin-zhi L. [5-HT descending expressing in the dorsal horn of cat spinal cord after deafferentation]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. vol 41. issue 5. 2011-09-29. PMID:21302446. |
[5-ht descending expressing in the dorsal horn of cat spinal cord after deafferentation]. |
2011-09-29 |
2023-08-12 |
cat |
| Jian-jun Chen, Qin Yang, Xin-zhi L. [5-HT descending expressing in the dorsal horn of cat spinal cord after deafferentation]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. vol 41. issue 5. 2011-09-29. PMID:21302446. |
to investigate the serotonin (5-ht) expression in dorsal horn of cat spinal cord and the atypical complex terminal (act) after complete dorsal rhizotomy. |
2011-09-29 |
2023-08-12 |
cat |
| E Pearlstein, H Bras, E S Deneris, L Vina. Contribution of 5-HT to locomotion - the paradox of Pet-1(-/-) mice. The European journal of neuroscience. vol 33. issue 10. 2011-09-26. PMID:21501257. |
we first confirmed, by means of immunohistochemistry, that there is a marked reduction of 5-ht innervation in the lumbar spinal cord of pet-1(-/-) mice. |
2011-09-26 |
2023-08-12 |
mouse |
| E Pearlstein, H Bras, E S Deneris, L Vina. Contribution of 5-HT to locomotion - the paradox of Pet-1(-/-) mice. The European journal of neuroscience. vol 33. issue 10. 2011-09-26. PMID:21501257. |
fictive locomotion was induced in the in vitro neonatal mouse spinal cord preparation by bath application of n-methyl-d,l-aspartate (nma) alone or together with dopamine and 5-ht. |
2011-09-26 |
2023-08-12 |
mouse |
| Roger R Dmochowsk. Duloxetine: a summary of published clinical experience. Reviews in urology. vol 6 Suppl 3. 2011-07-14. PMID:16985865. |
rhabdosphincter contractility changes are thought to occur as the result of increased stimulation of alpha(1)-adrenergic and 5-ht(2) receptors in the sacral spinal cord, resulting in increased efferent pudendal nerve activity, producing increased pelvic floor tonus. |
2011-07-14 |
2023-08-12 |
Not clear |
| Wolfgang H Jost, Parvaneh Marsale. Duloxetine in the treatment of stress urinary incontinence. Therapeutics and clinical risk management. vol 1. issue 4. 2011-07-14. PMID:18360568. |
the efficacy of duloxetine in sui is based on the inhibition of the presynaptic reuptake of 5-ht and ne in onuf's nucleus of the sacral spinal cord, whereby it may increase the concentration of 5-ht and ne in the synaptic cleft. |
2011-07-14 |
2023-08-12 |
cat |
| Sanjay Sinha, Sreenivasa R Sirigiri, Srinivas K Kanakamedala, Manoj K Singh, Rakesh M Sharm. Duloxetine for treatment of male sphincteric incontinence following partial conus medullaris infarction after coronary bypass surgery. Cases journal. vol 2. 2011-07-14. PMID:20062731. |
vascular spinal cord injury following coronary bypass grafting surgery is very rare and this is probably one of few reports of a presumptive partial conus medullaris lesion leading to sudden onset bladder and bowel incontinence which was managed using duloxetine, a selective serotonin and norepinephrine reuptake inhibitor. |
2011-07-14 |
2023-08-12 |
Not clear |
| Lucy A Bee, Anthony H Dickenso. The importance of the descending monoamine system for the pain experience and its treatment. F1000 medicine reports. vol 1. 2011-07-14. PMID:20948695. |
there is good evidence for a prominent α(2) adrenoceptor-mediated inhibitory system and for 5-ht(3) receptor-mediated excitatory control of spinal cord activity that originates in supraspinal areas. |
2011-07-14 |
2023-08-12 |
Not clear |
| Katherine C Murray, Marilee J Stephens, Edmund W Ballou, Charles J Heckman, David J Bennet. Motoneuron excitability and muscle spasms are regulated by 5-HT2B and 5-HT2C receptor activity. Journal of neurophysiology. vol 105. issue 2. 2011-06-16. PMID:20980537. |
immediately after spinal cord injury (sci), a devastating paralysis results from the loss of brain stem and cortical innervation of spinal neurons that control movement, including a loss of serotonergic (5-ht) innervation of motoneurons. |
2011-06-16 |
2023-08-12 |
rat |
| Katherine C Murray, Marilee J Stephens, Edmund W Ballou, Charles J Heckman, David J Bennet. Motoneuron excitability and muscle spasms are regulated by 5-HT2B and 5-HT2C receptor activity. Journal of neurophysiology. vol 105. issue 2. 2011-06-16. PMID:20980537. |
however, antagonists that are known to specifically be neutral antagonists at 5-ht(2b/c) receptors (e.g., rs127445) had no effect when given by themselves, indicating that these receptors were not activated by residual 5-ht in the spinal cord. |
2011-06-16 |
2023-08-12 |
rat |
| K Fouad, M M Rank, R Vavrek, K C Murray, L Sanelli, D J Bennet. Locomotion after spinal cord injury depends on constitutive activity in serotonin receptors. Journal of neurophysiology. vol 104. issue 6. 2011-05-09. PMID:20861436. |
locomotion after spinal cord injury depends on constitutive activity in serotonin receptors. |
2011-05-09 |
2023-08-12 |
rat |
| K Fouad, M M Rank, R Vavrek, K C Murray, L Sanelli, D J Bennet. Locomotion after spinal cord injury depends on constitutive activity in serotonin receptors. Journal of neurophysiology. vol 104. issue 6. 2011-05-09. PMID:20861436. |
following spinal cord injury (sci) neurons caudal to the injury are capable of rhythmic locomotor-related activity that can form the basis for substantial functional recovery of stepping despite the loss of crucial brain stem-derived neuromodulators like serotonin (5-ht). |
2011-05-09 |
2023-08-12 |
rat |
| K Fouad, M M Rank, R Vavrek, K C Murray, L Sanelli, D J Bennet. Locomotion after spinal cord injury depends on constitutive activity in serotonin receptors. Journal of neurophysiology. vol 104. issue 6. 2011-05-09. PMID:20861436. |
thus while normal rats can compensate for loss of 5-ht(2) receptor activity, after severe spinal cord injury rats require constitutive activity in these 5-ht(2) receptors to produce locomotion. |
2011-05-09 |
2023-08-12 |
rat |
| Jian Huang, Yanmei Fan, Yue Jia, Yanguo Hon. Antagonism of 5-HT(2A) receptors inhibits the expression of pronociceptive mediator and enhances endogenous opioid mechanism in carrageenan-induced inflammation in rats. European journal of pharmacology. vol 654. issue 1. 2011-04-25. PMID:21185821. |
the present study aimed to investigate neurochemical changes at the site of inflammation and in dorsal root ganglia (drg) and the spinal cord following the blockade of 5-ht(2a) receptors. |
2011-04-25 |
2023-08-12 |
rat |
| T Oe, M Tsukamoto, Y Nagakur. Reserpine causes biphasic nociceptive sensitivity alteration in conjunction with brain biogenic amine tones in rats. Neuroscience. vol 169. issue 4. 2011-04-18. PMID:20600634. |
a single injection of reserpine (3 mg/kg s.c.) significantly decreased biogenic amines in the spinal cord (sc), thalamus (tha), and prefrontal cortex (pfc) in both acute and chronic phases, but significantly increased a dopamine metabolite 3,4-dihydroxyphenylacetic acid (dopac) in the sc and a serotonin metabolite 5-hydroxyindoleacetic acid (5-hiaa) in the sc and tha in acute phase. |
2011-04-18 |
2023-08-12 |
rat |
| Hyung Gon Lee, Woong Mo Kim, Cheon Hee Park, Myung Ha Yoo. Roles of adenosine and serotonin receptors on the antinociception of sildenafil in the spinal cord of rats. Yonsei medical journal. vol 51. issue 6. 2011-04-06. PMID:20879067. |
roles of adenosine and serotonin receptors on the antinociception of sildenafil in the spinal cord of rats. |
2011-04-06 |
2023-08-12 |
rat |
| Yuefeng Lu, Kimberly L Simpson, Kristin J Weaver, Rick C S Li. Coexpression of serotonin and nitric oxide in the raphe complex: cortical versus subcortical circuit. Anatomical record (Hoboken, N.J. : 2007). vol 293. issue 11. 2011-02-10. PMID:20734426. |
the goal of this investigation was, therefore, to examine the coexpression of tryptophan hydroxylase (tph; the rate limiting enzyme for the synthesis of serotonin) and neuronal no synthase (nnos) in the ascending cortical projecting raphe nuclei (b6-b9 subgroups), when compared with the descending spinal cord projecting raphe nuclei (b1-b3 subgroups). |
2011-02-10 |
2023-08-12 |
Not clear |
| Yuefeng Lu, Kimberly L Simpson, Kristin J Weaver, Rick C S Li. Coexpression of serotonin and nitric oxide in the raphe complex: cortical versus subcortical circuit. Anatomical record (Hoboken, N.J. : 2007). vol 293. issue 11. 2011-02-10. PMID:20734426. |
our data demonstrated that: (1) a significant number of raphe-cortical projecting neurons was identified not only in the midline subgroup of dorsal raphe (b6, 7) but also in the median raphe (b8), as well as in the supralemniscal nucleus (b9); (2) serotonergic cortical projecting neurons from these three raphe nuclei exhibited a high (>80%) percentage of coexpression with nnos immunoreactivity; (3) similarly, serotonin transporter immunoreactive fibers in the medial prefrontal cortex were also double-labeled with nnos immunoreactivity; (4) in contrast, the descending spinal cord projecting raphe nuclei revealed only tph but not nnos immunoreactivity. |
2011-02-10 |
2023-08-12 |
Not clear |