| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jennifer M Wenzel, Noah A Rauscher, Joseph F Cheer, Erik B Oleso. A role for phasic dopamine release within the nucleus accumbens in encoding aversion: a review of the neurochemical literature. ACS chemical neuroscience. vol 6. issue 1. 2015-09-10. PMID:25491156. |
recent evidence demonstrates that midbrain dopamine neurons are heterogeneous in their projection targets, responses to environmental stimuli, pharmacology, and influences on motivated behavior. |
2015-09-10 |
2023-08-13 |
Not clear |
| Ashley A Vena, Rueben A Gonzale. Temporal profiles dissociate regional extracellular ethanol versus dopamine concentrations. ACS chemical neuroscience. vol 6. issue 1. 2015-09-10. PMID:25537116. |
the temporal patterns of these "response ratios" differed across brain regions, possibly due to regional differences in the mechanisms underlying the decline of the dopamine signal associated with acute intravenous ethanol administration and/or to the differential effects of acute ethanol on the properties of subpopulations of midbrain dopamine neurons. |
2015-09-10 |
2023-08-13 |
Not clear |
| Ze-Gang Ma, Jian Xu, Tian-Wei Li. Quantitative assessment of the association between fibroblast growth factor 20 rs1721100 C/G polymorphism and the risk of sporadic Parkinson's diseases: a meta-analysis. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 36. issue 1. 2015-09-01. PMID:25030126. |
fibroblast growth factor 20 (fgf20) is a neurotrophic factor which enhances the survival of rat midbrain dopamine neurons. |
2015-09-01 |
2023-08-13 |
rat |
| Christopher D Fiorillo, William T Newsome, Wolfram Schult. The temporal precision of reward prediction in dopamine neurons. Nature neuroscience. vol 11. issue 8. 2015-08-24. PMID:18660807. |
midbrain dopamine neurons are activated when reward is greater than predicted, and this error signal could teach target neurons both the value of reward and when it will occur. |
2015-08-24 |
2023-08-12 |
Not clear |
| Ji-Yeun Park, Hwan Choi, Soonbong Baek, Jaehwan Jang, Ahreum Lee, Songhee Jeon, Jongpil Kim, Hi-Joon Par. p53 signalling mediates acupuncture-induced neuroprotection in Parkinson's disease. Biochemical and biophysical research communications. vol 460. issue 3. 2015-08-21. PMID:25827815. |
parkinson's disease (pd) is a progressive neurodegenerative disorder associated with a selective loss of dopamine (da) neurons in the substantia nigra of the midbrain. |
2015-08-21 |
2023-08-13 |
mouse |
| Omar M E Abdel-Sala. The paths to neurodegeneration in genetic Parkinson's disease. CNS & neurological disorders drug targets. vol 13. issue 9. 2015-08-19. PMID:25106632. |
parkinson's disease (pd) is a neurodegenerative disorder, which results from the loss of specific population of neurons, namely the pigmented dopamine secreting neurons of the substnatia nigra pars compatica (snpc) of midbrain. |
2015-08-19 |
2023-08-13 |
Not clear |
| Anna M W Taylor, Annie Castonguay, Alison J Taylor, Niall P Murphy, Atefeh Ghogha, Christopher Cook, Lihua Xue, Mary C Olmstead, Yves De Koninck, Christopher J Evans, Catherine M Cahil. Microglia disrupt mesolimbic reward circuitry in chronic pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 22. 2015-08-19. PMID:26041913. |
chronic pain attenuates midbrain dopamine (da) transmission, as evidenced by a decrease in opioid-evoked da release in the ventral striatum, suggesting that the occurrence of chronic pain impairs reward-related behaviors. |
2015-08-19 |
2023-08-13 |
mouse |
| Somayeh Ahmadiantehrani, Dorit Ro. Dopamine D2 receptor activation leads to an up-regulation of glial cell line-derived neurotrophic factor via Gβγ-Erk1/2-dependent induction of Zif268. Journal of neurochemistry. vol 125. issue 2. 2015-08-18. PMID:23373701. |
we found that treatment of both differentiated dopaminergic-like sh-sy5y cells and rat midbrain slices with the dopamine d2 receptor (d2r) agonist, quinpirole, triggered an increase in the expression of gdnf that was temporally preceded by an increase in the levels of zinc-finger protein 268 (zif268), a dna-binding transcription factor encoded by an immediate-early gene. |
2015-08-18 |
2023-08-12 |
rat |
| Alan E Stewart, Kathryn A Roecklein, Susan Tanner, Michael G Kimli. Possible contributions of skin pigmentation and vitamin D in a polyfactorial model of seasonal affective disorder. Medical hypotheses. vol 83. issue 5. 2015-08-18. PMID:25270233. |
there are several reasons for this position: 1. vitamin d levels fluctuate in the body seasonally, with a lag, in direct relation to seasonally-available sunlight; 2. lower vitamin d levels have been observed in depressed patients (as well as in patients with other psychiatric disorders) compared to controls; 3. vitamin d levels in the central nervous system affect the production of both serotonin and dopamine; and 4. vitamin d and vitamin d responsive elements are found throughout the midbrain regions and are especially concentrated in the hypothalamus, a region that encompasses the circadian timing systems and much of its neural circuitry. |
2015-08-18 |
2023-08-13 |
Not clear |
| Philip Jean-Richard Dit Bressel, Gavan P McNall. The role of the lateral habenula in punishment. PloS one. vol 9. issue 11. 2015-08-18. PMID:25365401. |
the lhb is known to modulate midbrain dopamine (da) neurons, including inhibition of ventral tegmental area (vta) neurons via glutamatergic excitation of the gabaergic rostromedial tegmental nucleus (rmtg). |
2015-08-18 |
2023-08-13 |
rat |
| Andrew Oster, Philippe Faure, Boris S Gutki. Mechanisms for multiple activity modes of VTA dopamine neurons. Frontiers in computational neuroscience. vol 9. 2015-08-18. PMID:26283955. |
midbrain ventral segmental area (vta) dopaminergic neurons send numerous projections to cortical and sub-cortical areas, and diffusely release dopamine (da) to their targets. |
2015-08-18 |
2023-08-13 |
Not clear |
| Bozena E Fyk-Kolodziej, Takashi Shimano, Dana Gafoor, Najab Mirza, Ronald D Griffith, Tzy-Wen Gong, Avril Genene Hol. Dopamine in the auditory brainstem and midbrain: co-localization with amino acid neurotransmitters and gene expression following cochlear trauma. Frontiers in neuroanatomy. vol 9. 2015-08-10. PMID:26257610. |
dopamine in the auditory brainstem and midbrain: co-localization with amino acid neurotransmitters and gene expression following cochlear trauma. |
2015-08-10 |
2023-08-13 |
Not clear |
| Linh C Dang, James P O'Neil, William J Jagus. Genetic effects on behavior are mediated by neurotransmitters and large-scale neural networks. NeuroImage. vol 66. 2015-08-06. PMID:23142068. |
dopamine synthesis in the midbrain and ventral striatum affected functional connectivity in the default mode network, likely through the mesocorticolimbic pathway, in an inverted-u pattern with greater functional connectivity in medial pfc associated with intermediate levels of comt activity and dopamine. |
2015-08-06 |
2023-08-12 |
Not clear |
| Ariadna Laguna, Nicoletta Schintu, André Nobre, Alexandra Alvarsson, Nikolaos Volakakis, Jesper Kjaer Jacobsen, Marta Gómez-Galán, Elena Sopova, Eliza Joodmardi, Takashi Yoshitake, Qiaolin Deng, Jan Kehr, Johan Ericson, Per Svenningsson, Oleg Shupliakov, Thomas Perlman. Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease. Nature neuroscience. vol 18. issue 6. 2015-08-06. PMID:25915474. |
lmx1a and lmx1b are key transcription factors required for the early specification of ventral midbrain dopamine (mda) neurons. |
2015-08-06 |
2023-08-13 |
human |
| Manuela C Matesan, Donna J Cross, David H Lewis, Satoshi Minoshim. Differential alterations of dopamine transporter in the striatum and midbrain in patients with parkinsonian syndrome. Clinical nuclear medicine. vol 40. issue 3. 2015-07-30. PMID:25546191. |
differential alterations of dopamine transporter in the striatum and midbrain in patients with parkinsonian syndrome. |
2015-07-30 |
2023-08-13 |
Not clear |
| Manuela C Matesan, Donna J Cross, David H Lewis, Satoshi Minoshim. Differential alterations of dopamine transporter in the striatum and midbrain in patients with parkinsonian syndrome. Clinical nuclear medicine. vol 40. issue 3. 2015-07-30. PMID:25546191. |
in this study, we examined dopamine transporter (dat) density in the striatum versus midbrain (mb) in patients with nigrostriatal denervation. |
2015-07-30 |
2023-08-13 |
Not clear |
| Ulrika Nordströma, Geneviève Beauvais, Anamitra Ghosh, Baby Chakrapani Pulikkaparambil Sasidharan, Martin Lundblad, Julia Fuchs, Rajiv L Joshi, Jack W Lipton, Andrew Roholt, Satish Medicetty, Timothy N Feinstein, Jennifer A Steiner, Martha L Escobar Galvis, Alain Prochiantz, Patrik Brundi. Progressive nigrostriatal terminal dysfunction and degeneration in the engrailed1 heterozygous mouse model of Parkinson's disease. Neurobiology of disease. vol 73. 2015-07-29. PMID:25281317. |
indeed, a mouse that lacks one en1 allele exhibits decreased mitochondrial complex i activity and progressive midbrain dopamine neuron degeneration in adulthood, both features associated with pd. |
2015-07-29 |
2023-08-13 |
mouse |
| Gael Le Douaron, Fanny Schmidt, Majid Amar, Hanane Kadar, Lucila Debortoli, Alexandra Latini, Blandine Séon-Méniel, Laurent Ferrié, Patrick Pierre Michel, David Touboul, Alain Brunelle, Rita Raisman-Vozari, Bruno Figadèr. Neuroprotective effects of a brain permeant 6-aminoquinoxaline derivative in cell culture conditions that model the loss of dopaminergic neurons in Parkinson disease. European journal of medicinal chemistry. vol 89. 2015-07-24. PMID:25462259. |
parkinson disease is a neurodegenerative disorder of aging, characterized by disabling motor symptoms resulting from the loss of midbrain dopaminergic neurons and the decrease of dopamine in the striatum. |
2015-07-24 |
2023-08-13 |
mouse |
| Chris R Bye, Marie E Jönsson, Anders Björklund, Clare L Parish, Lachlan H Thompso. Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 15. 2015-07-24. PMID:25775569. |
transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors. |
2015-07-24 |
2023-08-13 |
rat |
| Chris R Bye, Marie E Jönsson, Anders Björklund, Clare L Parish, Lachlan H Thompso. Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 15. 2015-07-24. PMID:25775569. |
although cell sorting has been an anticipated strategy, its application has been limited by lack of knowledge regarding transmembrane proteins that can be used to target and isolate progenitors for midbrain dopamine (mda) neurons. |
2015-07-24 |
2023-08-13 |
rat |