| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lydia Kotecki, Matthew Hearing, Nora M McCall, Ezequiel Marron Fernandez de Velasco, Marco Pravetoni, Devinder Arora, Nicole C Victoria, Michaelanne B Munoz, Zhilian Xia, Paul A Slesinger, C David Weaver, Kevin Wickma. GIRK Channels Modulate Opioid-Induced Motor Activity in a Cell Type- and Subunit-Dependent Manner. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 18. 2015-07-24. PMID:25948263. |
girk channel activation has also been implicated in the opioid-induced inhibition of midbrain gaba neurons and consequent disinhibition of dopamine (da) neurons in the ventral tegmental area (vta). |
2015-07-24 |
2023-08-13 |
mouse |
| Shane Grealish, Elsa Diguet, Agnete Kirkeby, Bengt Mattsson, Andreas Heuer, Yann Bramoulle, Nadja Van Camp, Anselme L Perrier, Philippe Hantraye, Anders Björklund, Malin Parma. Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease. Cell stem cell. vol 15. issue 5. 2015-07-16. PMID:25517469. |
here we provide a comprehensive preclinical assessment of hesc-derived midbrain dopamine neurons in a rat model of pd. |
2015-07-16 |
2023-08-13 |
human |
| Kun Qian, Na Yu, Kristal R Tucker, Edwin S Levitan, Carmen C Canavie. Mathematical analysis of depolarization block mediated by slow inactivation of fast sodium channels in midbrain dopamine neurons. Journal of neurophysiology. vol 112. issue 11. 2015-07-13. PMID:25185810. |
mathematical analysis of depolarization block mediated by slow inactivation of fast sodium channels in midbrain dopamine neurons. |
2015-07-13 |
2023-08-13 |
rat |
| Romain Bourdy, María-José Sánchez-Catalán, Jennifer Kaufling, Judith J Balcita-Pedicino, Marie-José Freund-Mercier, Pierre Veinante, Susan R Sesack, François Georges, Michel Barro. Control of the nigrostriatal dopamine neuron activity and motor function by the tail of the ventral tegmental area. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 12. 2015-07-10. PMID:24896615. |
midbrain dopamine neurons are implicated in various psychiatric and neurological disorders. |
2015-07-10 |
2023-08-13 |
Not clear |
| Romain Bourdy, María-José Sánchez-Catalán, Jennifer Kaufling, Judith J Balcita-Pedicino, Marie-José Freund-Mercier, Pierre Veinante, Susan R Sesack, François Georges, Michel Barro. Control of the nigrostriatal dopamine neuron activity and motor function by the tail of the ventral tegmental area. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 12. 2015-07-10. PMID:24896615. |
the gabaergic tail of the ventral tegmental area (tvta), also named the rostromedial tegmental nucleus (rmtg), displays dense projections to the midbrain and exerts electrophysiological control over dopamine cells of the vta. |
2015-07-10 |
2023-08-13 |
Not clear |
| Fahad A Somaa, Christopher R Bye, Lachlan H Thompson, Clare L Paris. Meningeal cells influence midbrain development and the engraftment of dopamine progenitors in Parkinsonian mice. Experimental neurology. vol 267. 2015-07-06. PMID:25708989. |
meningeal cells influence midbrain development and the engraftment of dopamine progenitors in parkinsonian mice. |
2015-07-06 |
2023-08-13 |
mouse |
| Ritchie E Brown, James T McKenn. Turning a Negative into a Positive: Ascending GABAergic Control of Cortical Activation and Arousal. Frontiers in neurology. vol 6. 2015-06-30. PMID:26124745. |
ventral tegmental area gabaergic neurons, neighboring midbrain dopamine neurons, project to the frontal cortex and nucleus accumbens. |
2015-06-30 |
2023-08-13 |
Not clear |
| Sivaramakrishnan Kaveri, Hiroyuki Nakahar. Dual reward prediction components yield Pavlovian sign- and goal-tracking. PloS one. vol 9. issue 10. 2015-06-29. PMID:25310184. |
reinforcement learning (rl) has become a dominant paradigm for understanding animal behaviors and neural correlates of decision-making, in part because of its ability to explain pavlovian conditioned behaviors and the role of midbrain dopamine activity as reward prediction error (rpe). |
2015-06-29 |
2023-08-13 |
rat |
| Nicholas I Cilz, Lalitha Kurada, Binqi Hu, Saobo Le. Dopaminergic modulation of GABAergic transmission in the entorhinal cortex: concerted roles of α1 adrenoreceptors, inward rectifier K⁺, and T-type Ca²⁺ channels. Cerebral cortex (New York, N.Y. : 1991). vol 24. issue 12. 2015-06-25. PMID:23843440. |
whereas the entorhinal cortex (ec) receives profuse dopaminergic innervations from the midbrain, the effects of dopamine (da) on γ-aminobutyric acid (gaba)ergic interneurons in this brain region have not been determined. |
2015-06-25 |
2023-08-12 |
Not clear |
| Spyridon Theofilopoulos, Ernest Arena. Liver X receptors and cholesterol metabolism: role in ventral midbrain development and neurodegeneration. F1000prime reports. vol 7. 2015-06-22. PMID:26097711. |
moreover, specific cholesterol derivatives present in the midbrain or in the cerebrospinal fluid were identified as lxr ligands, capable of specifically and selectively regulating neurogenesis and the survival of distinct neuronal populations, including midbrain dopamine neurons. |
2015-06-22 |
2023-08-13 |
Not clear |
| Kelly M Lohr, Gary W Mille. VMAT2 and Parkinson's disease: harnessing the dopamine vesicle. Expert review of neurotherapeutics. vol 14. issue 10. 2015-06-16. PMID:25220836. |
therapeutic manipulation of vmat2 level or function has the potential to improve efficacy of dopamine derived from administered levodopa, increase dopamine neurotransmission from remaining midbrain dopamine neurons and protect against neurotoxic insults. |
2015-06-16 |
2023-08-13 |
mouse |
| Dustin R Wakeman, Stephanie Weiss, John R Sladek, John D Elsworth, Brian Bauereis, Csaba Leranth, Patrick J Hurley, Robert H Roth, D Eugene Redmon. Survival and integration of neurons derived from human embryonic stem cells in MPTP-lesioned primates. Cell transplantation. vol 23. issue 8. 2015-05-27. PMID:23562290. |
these results suggest that dopamine neuronal cells derived from neuroectoderm in vitro will not maintain the correct midbrain phenotype in vivo in nonhuman primates, contrasted with recent studies showing dopamine neuronal survival using an alternative floorplate method. |
2015-05-27 |
2023-08-12 |
human |
| Lia Panman, Maria Papathanou, Ariadna Laguna, Tony Oosterveen, Nikolaos Volakakis, Dario Acampora, Idha Kurtsdotter, Takashi Yoshitake, Jan Kehr, Eliza Joodmardi, Jonas Muhr, Antonio Simeone, Johan Ericson, Thomas Perlman. Sox6 and Otx2 control the specification of substantia nigra and ventral tegmental area dopamine neurons. Cell reports. vol 8. issue 4. 2015-05-26. PMID:25127144. |
distinct midbrain dopamine (mda) neuron subtypes are found in the substantia nigra pars compacta (snc) and the ventral tegmental area (vta), but it is mainly snc neurons that degenerate in parkinson's disease. |
2015-05-26 |
2023-08-13 |
Not clear |
| Joachim Morren. Dopamine neurons coding prediction errors in reward space, but not in aversive space: a matter of location? Journal of neurophysiology. vol 112. issue 5. 2015-05-11. PMID:24572096. |
dopamine midbrain neurons are well known for prediction error coding in a reward context. |
2015-05-11 |
2023-08-12 |
human |
| Peng Zhong, Yong Liu, Ying Hu, Tong Wang, Yong-ping Zhao, Qing-song Li. BDNF interacts with endocannabinoids to regulate cocaine-induced synaptic plasticity in mouse midbrain dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 10. 2015-05-06. PMID:25762688. |
bdnf interacts with endocannabinoids to regulate cocaine-induced synaptic plasticity in mouse midbrain dopamine neurons. |
2015-05-06 |
2023-08-13 |
mouse |
| Peng Zhong, Yong Liu, Ying Hu, Tong Wang, Yong-ping Zhao, Qing-song Li. BDNF interacts with endocannabinoids to regulate cocaine-induced synaptic plasticity in mouse midbrain dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 10. 2015-05-06. PMID:25762688. |
we report that bdnf and selective tyrosine kinase receptor b (trkb) agonist 7,8-dihydroxyflavone (dhf) activated the trkb receptor to facilitate two forms of ecb-mediated synaptic depression, depolarization-induced suppression of inhibition (dsi), and long-term depression (i-ltd) of ipscs in ventral tegmental area dopamine neurons in mouse midbrain slices. |
2015-05-06 |
2023-08-13 |
mouse |
| Felice Iasevoli, Luigi Aloj, Gianmarco Latte, Livia Avvisati, Federica Marmo, Carmine Tomasetti, Elisabetta F Buonaguro, Chiara Simeoli, Rosario Pivonello, Annamaria Colao, Andrea de Bartolomei. The glucocorticoid analog dexamethasone alters the expression and the distribution of dopamine receptors and enkephalin within cortico-subcortical regions. Current molecular pharmacology. vol 6. issue 3. 2015-05-04. PMID:23862670. |
we acutely exposed sprague-dawley rats to dexamethasone, a glucocorticoid analog, or vehicle and evaluated the mrna expression of dopamine d1 and d2 receptors and enkephalin within the cortex, the striatum, and the midbrain. |
2015-05-04 |
2023-08-12 |
rat |
| Hai-Ying Zhang, Ming Gao, Qing-Rong Liu, Guo-Hua Bi, Xia Li, Hong-Ju Yang, Eliot L Gardner, Jie Wu, Zheng-Xiong X. Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 46. 2015-04-23. PMID:25368177. |
cannabinoid cb2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice. |
2015-04-23 |
2023-08-13 |
mouse |
| Penelope J Hallett, Oliver Cooper, Damaso Sadi, Harold Robertson, Ivar Mendez, Ole Isacso. Long-term health of dopaminergic neuron transplants in Parkinson's disease patients. Cell reports. vol 7. issue 6. 2015-04-16. PMID:24910427. |
to determine the long-term health and function of transplanted dopamine neurons in parkinson's disease (pd) patients, the expression of dopamine transporters (dats) and mitochondrial morphology were examined in human fetal midbrain cellular transplants. |
2015-04-16 |
2023-08-13 |
human |
| Na Yu, Carmen C Canavie. A Mathematical Model of a Midbrain Dopamine Neuron Identifies Two Slow Variables Likely Responsible for Bursts Evoked by SK Channel Antagonists and Terminated by Depolarization Block. Journal of mathematical neuroscience. vol 5. 2015-04-08. PMID:25852980. |
a mathematical model of a midbrain dopamine neuron identifies two slow variables likely responsible for bursts evoked by sk channel antagonists and terminated by depolarization block. |
2015-04-08 |
2023-08-13 |
Not clear |