| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elizabeth E Steinberg, Josiah R Boivin, Benjamin T Saunders, Ilana B Witten, Karl Deisseroth, Patricia H Jana. Positive reinforcement mediated by midbrain dopamine neurons requires D1 and D2 receptor activation in the nucleus accumbens. PloS one. vol 9. issue 4. 2015-01-19. PMID:24733061. |
positive reinforcement mediated by midbrain dopamine neurons requires d1 and d2 receptor activation in the nucleus accumbens. |
2015-01-19 |
2023-08-13 |
human |
| Shane W Savage, David H Zald, Ronald L Cowan, Nora D Volkow, Pamela A Marks-Shulman, Robert M Kessler, Naji N Abumrad, Julia P Dun. Regulation of novelty seeking by midbrain dopamine D2/D3 signaling and ghrelin is altered in obesity. Obesity (Silver Spring, Md.). vol 22. issue 6. 2015-01-16. PMID:24415718. |
regulation of novelty seeking by midbrain dopamine d2/d3 signaling and ghrelin is altered in obesity. |
2015-01-16 |
2023-08-12 |
Not clear |
| Shane W Savage, David H Zald, Ronald L Cowan, Nora D Volkow, Pamela A Marks-Shulman, Robert M Kessler, Naji N Abumrad, Julia P Dun. Regulation of novelty seeking by midbrain dopamine D2/D3 signaling and ghrelin is altered in obesity. Obesity (Silver Spring, Md.). vol 22. issue 6. 2015-01-16. PMID:24415718. |
to investigate the relationship of novelty seeking traits (ns) with midbrain dopamine (da) receptors and acyl ghrelin levels (ag) in normal weight (nw) and obese females.ns predict addictive behaviors and are hypothesized to contribute to eating behaviors. |
2015-01-16 |
2023-08-12 |
Not clear |
| Minryung R Song, Jean-Marc Fellou. Value learning and arousal in the extinction of probabilistic rewards: the role of dopamine in a modified temporal difference model. PloS one. vol 9. issue 2. 2015-01-09. PMID:24586823. |
midbrain dopamine neurons were suggested to play a role in both arousal and learning reward values. |
2015-01-09 |
2023-08-12 |
rat |
| Elyssa B Margolis, Gregory O Hjelmstad, Wakako Fujita, Howard L Field. Direct bidirectional μ-opioid control of midbrain dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 44. 2015-01-06. PMID:25355223. |
direct bidirectional μ-opioid control of midbrain dopamine neurons. |
2015-01-06 |
2023-08-13 |
rat |
| Elizabeth M Hartfield, Michiko Yamasaki-Mann, Hugo J Ribeiro Fernandes, Jane Vowles, William S James, Sally A Cowley, Richard Wade-Martin. Physiological characterisation of human iPS-derived dopaminergic neurons. PloS one. vol 9. issue 2. 2015-01-02. PMID:24586273. |
we first generated and differentiated hipsc lines into midbrain dopaminergic neurons and performed a comprehensive characterisation to confirm dopaminergic functionality by demonstrating dopamine synthesis, release, and re-uptake. |
2015-01-02 |
2023-08-12 |
human |
| Li Hui, Jing Qin Wu, Xuan Zhang, Jie Lv, Wei Li Du, Chang Gui Kou, Ya Qin Yu, Meng Han Lv, Da Chun Chen, Xiang Yang Zhan. Association between the angiotensin-converting enzyme gene insertion/deletion polymorphism and first-episode patients with schizophrenia in a Chinese Han population. Human psychopharmacology. vol 29. issue 3. 2014-12-28. PMID:24615782. |
angiotensin-converting enzyme (ace), a key enzyme of the renin-angiotensin system, can modulate dopamine turnover in the midbrain. |
2014-12-28 |
2023-08-12 |
Not clear |
| Hiroyuki Nakahar. Multiplexing signals in reinforcement learning with internal models and dopamine. Current opinion in neurobiology. vol 25. 2014-12-23. PMID:24463329. |
remarkable progress has been made in the field, guided by the midbrain dopamine reward prediction error hypothesis and the underlying reinforcement learning framework, which does not involve internal models ('model-free'). |
2014-12-23 |
2023-08-12 |
Not clear |
| Erica L Unger, Laura E Bianco, Byron C Jones, Richard P Allen, Christopher J Earle. Low brain iron effects and reversibility on striatal dopamine dynamics. Experimental neurology. vol 261. 2014-12-17. PMID:24999026. |
iron deficiency (id) in rodents leads to decreased ventral midbrain (vmb) iron concentrations and to changes in the dopamine (da) system that mimic many of the dopaminergic changes seen in rls patient where low substantia nigra iron is a known pathology of the disease. |
2014-12-17 |
2023-08-13 |
rat |
| Ling Hu, Xiang-Hong Jing, Cai-Lian Cui, Guo-Gang Xing, Bing Zh. NMDA receptors in the midbrain play a critical role in dopamine-mediated hippocampal synaptic potentiation caused by morphine. Addiction biology. vol 19. issue 3. 2014-12-16. PMID:23163242. |
a single exposure to drugs of abuse produces an nmdar (n-methyl-d-aspartate receptor)-dependent synaptic potentiation at excitatory synapses of dopamine (da) neurons in the ventral tegmental area (vta) of the midbrain. |
2014-12-16 |
2023-08-12 |
rat |
| Huikun Wang, Carl R Lupic. Release of endogenous cannabinoids from ventral tegmental area dopamine neurons and the modulation of synaptic processes. Progress in neuro-psychopharmacology & biological psychiatry. vol 52. 2014-12-12. PMID:24495779. |
therefore, understanding how endocannabinoids are mobilized to modulate synaptic inputs impinging on midbrain dopamine neurons is crucial to a complete understanding of the roles that these molecules play in reward behavior, drug abuse and addiction. |
2014-12-12 |
2023-08-12 |
Not clear |
| Chemutai Sego, Luciano Gonçalves, Leandro Lima, Isadora C Furigo, Jose Donato, Martin Metzge. Lateral habenula and the rostromedial tegmental nucleus innervate neurochemically distinct subdivisions of the dorsal raphe nucleus in the rat. The Journal of comparative neurology. vol 522. issue 7. 2014-11-25. PMID:24374795. |
the inhibitory lhb influence on midbrain dopamine neurons has been shown to be mainly mediated by the rmtg, a mostly gabaergic nucleus that receives a dominant input from the lhbl. |
2014-11-25 |
2023-08-12 |
rat |
| Gerhard Jocham, Tilmann A Klein, Markus Ullsperge. Differential modulation of reinforcement learning by D2 dopamine and NMDA glutamate receptor antagonism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 39. 2014-11-25. PMID:25253860. |
the firing pattern of midbrain dopamine (da) neurons is well known to reflect reward prediction errors (pes), the difference between obtained and expected rewards. |
2014-11-25 |
2023-08-13 |
human |
| Joshua L Allen, Xiufang Liu, Douglas Weston, Katherine Conrad, Günter Oberdörster, Deborah A Cory-Slecht. Consequences of developmental exposure to concentrated ambient ultrafine particle air pollution combined with the adult paraquat and maneb model of the Parkinson's disease phenotype in male mice. Neurotoxicology. vol 41. 2014-11-14. PMID:24486957. |
absence of more extensive interactions might also reflect the finding that caps and pq+mb appeared to differentially target the nigrostriatal dopamine and amino acid systems, with caps impacting striatum and pq+mb impacting dopamine-glutamate function in midbrain; both caps and pq+mb elevated glutamate levels in these specific regions, consistent with potential excitotoxicity. |
2014-11-14 |
2023-08-12 |
mouse |
| Omar Gutierrez-Arenas, Olivia Eriksson, Jeanette Hellgren Kotalesk. Segregation and crosstalk of D1 receptor-mediated activation of ERK in striatal medium spiny neurons upon acute administration of psychostimulants. PLoS computational biology. vol 10. issue 1. 2014-11-12. PMID:24499932. |
the convergence of corticostriatal glutamate and dopamine from the midbrain in the striatal medium spiny neurons (msn) triggers synaptic plasticity that underlies reinforcement learning and pathological conditions such as psychostimulant addiction. |
2014-11-12 |
2023-08-12 |
Not clear |
| Simon R W Stott, Roger A Barke. Time course of dopamine neuron loss and glial response in the 6-OHDA striatal mouse model of Parkinson's disease. The European journal of neuroscience. vol 39. issue 6. 2014-11-07. PMID:24372914. |
the 6-hydroxydopamine (6-ohda) neurotoxic lesion of the midbrain dopamine (da) system is one of the most widely used techniques for modelling parkinson's disease in rodents. |
2014-11-07 |
2023-08-12 |
mouse |
| Catherine Jensen Peña, Y Dana Neugut, Cali A Calarco, Frances A Champagn. Effects of maternal care on the development of midbrain dopamine pathways and reward-directed behavior in female offspring. The European journal of neuroscience. vol 39. issue 6. 2014-11-07. PMID:24446918. |
effects of maternal care on the development of midbrain dopamine pathways and reward-directed behavior in female offspring. |
2014-11-07 |
2023-08-12 |
rat |
| Fahad Ali, Simon R W Stott, Roger A Barke. Stem cells and the treatment of Parkinson's disease. Experimental neurology. vol 260. 2014-11-04. PMID:23298521. |
we will also examine the various approaches used in cellular reprogramming and their differentiation into patient-specific midbrain dopamine neurons, with an emphasis particularly on modelling familial cases of pd to recapitulate disease phenotypes. |
2014-11-04 |
2023-08-12 |
human |
| Matteo Colomb. Deep and beautiful. The reward prediction error hypothesis of dopamine. Studies in history and philosophy of biological and biomedical sciences. vol 45. 2014-10-22. PMID:24252364. |
according to the reward-prediction error hypothesis (rpeh) of dopamine, the phasic activity of dopaminergic neurons in the midbrain signals a discrepancy between the predicted and currently experienced reward of a particular event. |
2014-10-22 |
2023-08-12 |
Not clear |
| Alan D Pickering, Francesca Pesol. Modeling dopaminergic and other processes involved in learning from reward prediction error: contributions from an individual differences perspective. Frontiers in human neuroscience. vol 8. 2014-10-17. PMID:25324752. |
phasic firing changes of midbrain dopamine neurons have been widely characterized as reflecting a reward prediction error (rpe). |
2014-10-17 |
2023-08-13 |
Not clear |