| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J N Berry, S E Engle, J M McIntosh, R M Drena. α6-Containing nicotinic acetylcholine receptors in midbrain dopamine neurons are poised to govern dopamine-mediated behaviors and synaptic plasticity. Neuroscience. vol 304. 2016-05-24. PMID:26210579. |
α6-containing nicotinic acetylcholine receptors in midbrain dopamine neurons are poised to govern dopamine-mediated behaviors and synaptic plasticity. |
2016-05-24 |
2023-08-13 |
mouse |
| J N Berry, S E Engle, J M McIntosh, R M Drena. α6-Containing nicotinic acetylcholine receptors in midbrain dopamine neurons are poised to govern dopamine-mediated behaviors and synaptic plasticity. Neuroscience. vol 304. 2016-05-24. PMID:26210579. |
acetylcholine (ach) acts through nicotinic and muscarinic ach receptors in the ventral midbrain and striatal areas to influence dopamine (da) transmission. |
2016-05-24 |
2023-08-13 |
mouse |
| Lalitha Madhavan, Brian F Daley, Beverly L Davidson, Ryan L Boudreau, Jack W Lipton, Allyson Cole-Strauss, Kathy Steece-Collier, Timothy J Collie. Sonic Hedgehog Controls the Phenotypic Fate and Therapeutic Efficacy of Grafted Neural Precursor Cells in a Model of Nigrostriatal Neurodegeneration. PloS one. vol 10. issue 9. 2016-05-20. PMID:26340267. |
overall these studies reveal core mechanisms fundamental to grafted npc-based therapeutic effects, and delineate the particular contributions of two graft-expressed molecules, shh and gdnf, in mediating midbrain dopamine neuron protection, and host plasticity after npc transplantation. |
2016-05-20 |
2023-08-13 |
rat |
| Javier Bles. Vive la difference! Dissecting the diversity of midbrain dopamine neurons. Movement disorders : official journal of the Movement Disorder Society. vol 31. issue 1. 2016-05-18. PMID:26686701. |
dissecting the diversity of midbrain dopamine neurons. |
2016-05-18 |
2023-08-13 |
Not clear |
| Sylvia Navailles, Karine Guillem, Caroline Vouillac-Mendoza, Serge H Ahme. Coordinated Recruitment of Cortical-Subcortical Circuits and Ascending Dopamine and Serotonin Neurons During Inhibitory Control of Cocaine Seeking in Rats. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 9. 2016-05-10. PMID:24872521. |
overall, we found that effective inhibitory control of cocaine seeking is associated with the coordinated recruitment of different top-down cortical-striatal circuits originating from different pfc territories, and of different bottom-up dopamine (da) and serotonin (5-ht) midbrain subsystems that normally modulate activity in these circuits. |
2016-05-10 |
2023-08-13 |
rat |
| Paul F Kramer, John T William. Cocaine Decreases Metabotropic Glutamate Receptor mGluR1 Currents in Dopamine Neurons by Activating mGluR5. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 10. 2016-05-09. PMID:25829143. |
midbrain dopamine neurons are important mediators of reward and movement and are sensitive to cocaine-induced plasticity. |
2016-05-09 |
2023-08-13 |
Not clear |
| Bettina Mai, Wolfgang Haube. Orbitofrontal or accumbens dopamine depletion does not affect risk-based decision making in rats. Cognitive, affective & behavioral neuroscience. vol 15. issue 3. 2016-05-09. PMID:25860659. |
considerable evidence has implicated dopamine (da) signals in target regions of midbrain da neurons such as the medial prefrontal cortex or the core region of the nucleus accumbens in controlling risk-based decision-making. |
2016-05-09 |
2023-08-13 |
rat |
| Kenji Morita, Yasuo Kawaguch. Computing reward-prediction error: an integrated account of cortical timing and basal-ganglia pathways for appetitive and aversive learning. The European journal of neuroscience. vol 42. issue 4. 2016-05-06. PMID:26095906. |
there are two prevailing notions regarding the involvement of the corticobasal ganglia system in value-based learning: (i) the direct and indirect pathways of the basal ganglia are crucial for appetitive and aversive learning, respectively, and (ii) the activity of midbrain dopamine neurons represents reward-prediction error. |
2016-05-06 |
2023-08-13 |
human |
| Gretchen L Snyder, Kimberly E Vanove. Intracellular signaling and approaches to the treatment of schizophrenia and associated cognitive impairment. Current pharmaceutical design. vol 20. issue 31. 2016-05-02. PMID:24345266. |
data support the long-standing concept of schizophrenia as a disease characterized by hyperactivity within midbrain (striatal d2) dopamine systems. |
2016-05-02 |
2023-08-12 |
Not clear |
| Iulia Glovaci, C Andrew Chapma. Activation of Phosphatidylinositol-Linked Dopamine Receptors Induces a Facilitation of Glutamate-Mediated Synaptic Transmission in the Lateral Entorhinal Cortex. PloS one. vol 10. issue 7. 2016-04-29. PMID:26133167. |
the lateral entorhinal cortex receives strong inputs from midbrain dopamine neurons that can modulate its sensory and mnemonic function. |
2016-04-29 |
2023-08-13 |
rat |
| Angela Anderegg, Jean-Francois Poulin, Rajeshwar Awatraman. Molecular heterogeneity of midbrain dopaminergic neurons--Moving toward single cell resolution. FEBS letters. vol 589. issue 24 Pt A. 2016-04-29. PMID:26505674. |
since their discovery, midbrain dopamine (da) neurons have been researched extensively, in part because of their diverse functions and involvement in various neuropsychiatric disorders. |
2016-04-29 |
2023-08-13 |
Not clear |
| Nora D Volkow, Marisela Morale. The Brain on Drugs: From Reward to Addiction. Cell. vol 162. issue 4. 2016-04-26. PMID:26276628. |
repeated drug administration triggers neuroplastic changes in glutamatergic inputs to the striatum and midbrain dopamine neurons, enhancing the brain's reactivity to drug cues, reducing the sensitivity to non-drug rewards, weakening self-regulation, and increasing the sensitivity to stressful stimuli and dysphoria. |
2016-04-26 |
2023-08-13 |
Not clear |
| Christine E Briggs, Yulei Wang, Benjamin Kong, Tsung-Ung W Woo, Lakshmanan K Iyer, Kai C Sonnta. Midbrain dopamine neurons in Parkinson's disease exhibit a dysregulated miRNA and target-gene network. Brain research. vol 1618. 2016-04-25. PMID:26047984. |
midbrain dopamine neurons in parkinson's disease exhibit a dysregulated mirna and target-gene network. |
2016-04-25 |
2023-08-13 |
Not clear |
| Xinmu Zhang, Yingzi Wang, Cheng Ma, Yan Yan, Yang Yang, Xin Wang, Wolf-Dieter Rausc. Ginsenoside Rd and ginsenoside Re offer neuroprotection in a novel model of Parkinson's disease. American journal of neurodegenerative disease. vol 5. issue 1. 2016-04-13. PMID:27073742. |
parkinson's disease is a progressive neurodegenerative movement disorder characterized by a profound loss of midbrain dopamine neurons in the substantia nigra pars compacta. |
2016-04-13 |
2023-08-13 |
Not clear |
| Eva Vergaño-Vera, Eva Díaz-Guerra, Eva Rodríguez-Traver, Héctor R Méndez-Gómez, Óscar Solís, Jaime Pignatelli, James Pickel, Sang-Hun Lee, Rosario Moratalla, Carlos Vicario-Abejó. Nurr1 blocks the mitogenic effect of FGF-2 and EGF, inducing olfactory bulb neural stem cells to adopt dopaminergic and dopaminergic-GABAergic neuronal phenotypes. Developmental neurobiology. vol 75. issue 8. 2016-04-12. PMID:25447275. |
our results indicate that nurr1 overexpression in obscs induces the formation of two populations of mature dopaminergic neurons with features of the ventral mesencephalon or of the ob, capable of responding to functional dopaminergic stimuli and of releasing dopamine. |
2016-04-12 |
2023-08-13 |
mouse |
| R Nisar, P S Hanson, L He, R W Taylor, P G Blain, C M Morri. Diquat causes caspase-independent cell death in SH-SY5Y cells by production of ROS independently of mitochondria. Archives of toxicology. vol 89. issue 10. 2016-04-06. PMID:25693864. |
diquat showed greater toxicity towards sh-sy5y neuroblastoma cells and human midbrain neural cells than paraquat and also mptp, which was independent of dopamine transporter-mediated uptake. |
2016-04-06 |
2023-08-13 |
human |
| Chunhai Chen, Qinglong Ma, Xiaowei Chen, Min Zhong, Ping Deng, Gang Zhu, Yanwen Zhang, Lei Zhang, Zhiqi Yang, Kuan Zhang, Lu Guo, Liting Wang, Zhengping Yu, Zhou Zho. Thyroid Hormone-Otx2 Signaling Is Required for Embryonic Ventral Midbrain Neural Stem Cells Differentiated into Dopamine Neurons. Stem cells and development. vol 24. issue 15. 2016-04-06. PMID:25867707. |
thyroid hormone-otx2 signaling is required for embryonic ventral midbrain neural stem cells differentiated into dopamine neurons. |
2016-04-06 |
2023-08-13 |
Not clear |
| Chunhai Chen, Qinglong Ma, Xiaowei Chen, Min Zhong, Ping Deng, Gang Zhu, Yanwen Zhang, Lei Zhang, Zhiqi Yang, Kuan Zhang, Lu Guo, Liting Wang, Zhengping Yu, Zhou Zho. Thyroid Hormone-Otx2 Signaling Is Required for Embryonic Ventral Midbrain Neural Stem Cells Differentiated into Dopamine Neurons. Stem cells and development. vol 24. issue 15. 2016-04-06. PMID:25867707. |
midbrain dopamine (da) neurons are essential for maintaining multiple brain functions. |
2016-04-06 |
2023-08-13 |
Not clear |
| Chunhai Chen, Qinglong Ma, Xiaowei Chen, Min Zhong, Ping Deng, Gang Zhu, Yanwen Zhang, Lei Zhang, Zhiqi Yang, Kuan Zhang, Lu Guo, Liting Wang, Zhengping Yu, Zhou Zho. Thyroid Hormone-Otx2 Signaling Is Required for Embryonic Ventral Midbrain Neural Stem Cells Differentiated into Dopamine Neurons. Stem cells and development. vol 24. issue 15. 2016-04-06. PMID:25867707. |
we find that thyroid hormone deficiency during development reduces the midbrain da neuron number, downregulates the expression of tyrosine hydroxylase (th) and the dopamine transporter (dat), and impairs the da neuron-dependent motor behavior. |
2016-04-06 |
2023-08-13 |
Not clear |
| Satoshi Ikemoto, Chen Yang, Aaron Ta. Basal ganglia circuit loops, dopamine and motivation: A review and enquiry. Behavioural brain research. vol 290. 2016-04-04. PMID:25907747. |
dopamine neurons located in the midbrain play a role in motivation that regulates approach behavior (approach motivation). |
2016-04-04 |
2023-08-13 |
Not clear |