| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bárbara Mendes-Pinheiro, Sandra I Anjo, Bruno Manadas, Jorge D Da Silva, Ana Marote, Leo A Behie, Fábio G Teixeira, António J Salgad. Bone Marrow Mesenchymal Stem Cells' Secretome Exerts Neuroprotective Effects in a Parkinson's Disease Rat Model. Frontiers in bioengineering and biotechnology. vol 7. 2020-10-01. PMID:31737616. |
parkinson's disease (pd) is characterized by a selective loss of dopamine (da) neurons in the human midbrain causing motor dysfunctions. |
2020-10-01 |
2023-08-13 |
human |
| Daniel de Castro Medeiros, Cleiton Lopes Aguiar, Márcio Flávio Dutra Moraes, Gilberto Fison. Sleep Disorders in Rodent Models of Parkinson's Disease. Frontiers in pharmacology. vol 10. 2020-10-01. PMID:31827439. |
they have been primarily designed to eliminate midbrain dopamine neurons and elicit motor impairment, which are the traditional pathological features of pd. |
2020-10-01 |
2023-08-13 |
mouse |
| Sylvie Dumas, Åsa Wallén-Mackenzi. Developmental Co-expression of Vglut2 and Nurr1 in a Mes-Di-Encephalic Continuum Preceeds Dopamine and Glutamate Neuron Specification. Frontiers in cell and developmental biology. vol 7. 2020-10-01. PMID:31850343. |
midbrain dopamine (da) neurons exist as several subtypes and are found in a heterogeneous environment including gabaergic and glutamatergic neurons as well as various types of co-releasing neurons. |
2020-10-01 |
2023-08-13 |
Not clear |
| Mengxi Yun, Takashi Kawai, Masafumi Nejime, Hiroshi Yamada, Masayuki Matsumot. Signal dynamics of midbrain dopamine neurons during economic decision-making in monkeys. Science advances. vol 6. issue 27. 2020-10-01. PMID:32937434. |
signal dynamics of midbrain dopamine neurons during economic decision-making in monkeys. |
2020-10-01 |
2023-08-13 |
monkey |
| Mengxi Yun, Takashi Kawai, Masafumi Nejime, Hiroshi Yamada, Masayuki Matsumot. Signal dynamics of midbrain dopamine neurons during economic decision-making in monkeys. Science advances. vol 6. issue 27. 2020-10-01. PMID:32937434. |
midbrain dopamine neurons are known to reinforce economic choices through their signal evoked by outcomes after decisions are made. |
2020-10-01 |
2023-08-13 |
monkey |
| Kelly H MacNiven, Josiah K Leong, Brian Knutso. Medial forebrain bundle structure is linked to human impulsivity. Science advances. vol 6. issue 38. 2020-10-01. PMID:32938676. |
comparative research indicates that projections from midbrain dopamine nuclei [including the ventral tegmental area (vta)] to the ventral striatum [including the nucleus accumbens (nacc)] critically support motivated behavior. |
2020-10-01 |
2023-08-13 |
human |
| Sara Brignani, R J Pasterkam. Neuronal Subset-Specific Migration and Axonal Wiring Mechanisms in the Developing Midbrain Dopamine System. Frontiers in neuroanatomy. vol 11. 2020-09-30. PMID:28740464. |
the midbrain dopamine (mda) system is involved in the control of cognitive and motor behaviors, and is associated with several psychiatric and neurodegenerative diseases. |
2020-09-30 |
2023-08-13 |
Not clear |
| Makoto Mizunami, Yukihisa Matsumot. Roles of Octopamine and Dopamine Neurons for Mediating Appetitive and Aversive Signals in Pavlovian Conditioning in Crickets. Frontiers in physiology. vol 8. 2020-09-30. PMID:29311961. |
in mammals, it has been shown that some classes of dopamine neurons in the midbrain mediate prediction error signals that govern the learning process, whereas other classes of dopamine neurons control execution of learned actions. |
2020-09-30 |
2023-08-13 |
cricket |
| Guo-Qing Wang, Dai-Di Li, Chun Huang, Di-Sheng Lu, Chao Zhang, Shao-Yu Zhou, Jie Liu, Feng Zhan. Icariin Reduces Dopaminergic Neuronal Loss and Microglia-Mediated Inflammation Frontiers in molecular neuroscience. vol 10. 2020-09-30. PMID:29375304. |
icariin reduces dopaminergic neuronal loss and microglia-mediated inflammation parkinson's disease (pd) is one of the most common neurodegenerative diseases characterized with a gradual loss of midbrain substantia nigra (sn) dopamine (da) neurons. |
2020-09-30 |
2023-08-13 |
rat |
| Roberto Coccurello, Mauro Maccarron. Hedonic Eating and the "Delicious Circle": From Lipid-Derived Mediators to Brain Dopamine and Back. Frontiers in neuroscience. vol 12. 2020-09-30. PMID:29740277. |
thus, the role of midbrain dopamine is positioned at the intersection between selected hormonal signals involved in food reward information processing (namely, leptin, ghrelin, and insulin), and lipid-derived neural mediators such as endocannabinoids. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ginetta Collo, Laura Cavalleri, Michele Zoli, Uwe Maskos, Emiliangelo Ratti, Emilio Merlo Pic. Alpha6-Containing Nicotinic Acetylcholine Receptors Mediate Nicotine-Induced Structural Plasticity in Mouse and Human iPSC-Derived Dopaminergic Neurons. Frontiers in pharmacology. vol 9. 2020-09-30. PMID:29910731. |
midbrain dopamine (da) neurons are considered a critical substrate for the reinforcing and sensitizing effects of nicotine and tobacco dependence. |
2020-09-30 |
2023-08-13 |
mouse |
| Erica J Melief, Jonathan W McKinley, Jonathan Y Lam, Nicole M Whiteley, Alec W Gibson, John F Neumaier, Charles W Henschen, Richard D Palmiter, Nigel S Bamford, Martin Darva. Loss of glutamate signaling from the thalamus to dorsal striatum impairs motor function and slows the execution of learned behaviors. NPJ Parkinson's disease. vol 4. 2020-09-30. PMID:30083593. |
parkinson's disease (pd) is primarily associated with the degeneration of midbrain dopamine neurons, but it is now appreciated that pathological processes like lewy-body inclusions and cell loss affect several other brain regions, including the central lateral (cl) and centromedian/parafascicular (cm/pf) thalamic regions. |
2020-09-30 |
2023-08-13 |
mouse |
| Bridget Martinez, Philip V Peplo. Neuroprotection by immunomodulatory agents in animal models of Parkinson's disease. Neural regeneration research. vol 13. issue 9. 2020-09-30. PMID:30127102. |
all of the agents were effective in reducing the motor deficit and alleviating dopaminergic neurotoxicity and, when measured, preventing the decrease of dopamine upon being administered therapeutically after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, 6-hydroxydopamine, rotenone-lesioning or delivery of adeno-associated virus-α-synuclein to the ventral midbrain of animals. |
2020-09-30 |
2023-08-13 |
Not clear |
| Yuko Nakamura, Naohiro Okada, Akira Kunimatsu, Kiyoto Kasai, Shinsuke Koik. Anatomical Templates of the Midbrain Ventral Tegmental Area and Substantia Nigra for Asian Populations. Frontiers in psychiatry. vol 9. 2020-09-30. PMID:30210369. |
considering that the ventral tegmental area (vta) and substantia nigra (sn) in the midbrain are the primary dopamine producers, creating reliable anatomical templates of the vta and sn through neuroimaging studies would be useful for achieving a detailed understanding of this dopaminergic system. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ada Ledonne, Nicola Biagio Mercur. mGluR1-Dependent Long Term Depression in Rodent Midbrain Dopamine Neurons Is Regulated by Neuregulin 1/ErbB Signaling. Frontiers in molecular neuroscience. vol 11. 2020-09-30. PMID:30327588. |
mglur1-dependent long term depression in rodent midbrain dopamine neurons is regulated by neuregulin 1/erbb signaling. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ada Ledonne, Nicola Biagio Mercur. mGluR1-Dependent Long Term Depression in Rodent Midbrain Dopamine Neurons Is Regulated by Neuregulin 1/ErbB Signaling. Frontiers in molecular neuroscience. vol 11. 2020-09-30. PMID:30327588. |
increasing evidence demonstrates that the neurotrophic factor neuregulin 1 (nrg1) and its receptors, erbb tyrosine kinases, modulate midbrain dopamine (da) transmission. |
2020-09-30 |
2023-08-13 |
Not clear |
| Chao Wei, Xiao Han, Danwei Weng, Qiru Feng, Xiangbing Qi, Jin Li, Minmin Lu. Response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and MDMA. Cell discovery. vol 4. 2020-09-30. PMID:30416749. |
response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and mdma. |
2020-09-30 |
2023-08-13 |
Not clear |
| Chao Wei, Xiao Han, Danwei Weng, Qiru Feng, Xiangbing Qi, Jin Li, Minmin Lu. Response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and MDMA. Cell discovery. vol 4. 2020-09-30. PMID:30416749. |
they are believed to target midbrain dopamine neurons and/or serotonin neurons, but their effects on the dynamic neuronal activity remain unclear in behaving states. |
2020-09-30 |
2023-08-13 |
Not clear |
| Edward J Robinson, Sebastian P Aguiar, Willemieke M Kouwenhoven, Dorinde S Starmans, Lars von Oerthel, Marten P Smidt, Lars P van der Heid. Survival of midbrain dopamine neurons depends on the Bcl2 factor Mcl1. Cell death discovery. vol 4. 2020-09-30. PMID:30479840. |
survival of midbrain dopamine neurons depends on the bcl2 factor mcl1. |
2020-09-30 |
2023-08-13 |
mouse |
| Nicole Petersen, Edythe D Londo. Addiction and Dopamine: Sex Differences and Insights from Studies of Smoking. Current opinion in behavioral sciences. vol 23. 2020-09-30. PMID:30746429. |
findings from research on cigarette smoking reveal sex differences in striatal and midbrain dopamine d2-type receptor availability and striatal dopamine release that suggest mechanisms of nicotine dependence, and stronger subjective responses to nicotine and efficacy of nicotine replacement therapies in male smokers than in their female counterparts. |
2020-09-30 |
2023-08-13 |
Not clear |