| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anil Joshi, Fanny Faivre, Susanne Eva la Fleur, Michel Barro. Midbrain and Lateral Nucleus Accumbens Dopamine Depletion Affects Free-choice High-fat high-sugar Diet Preference in Male Rats. Neuroscience. vol 467. 2021-07-12. PMID:34048800. |
to determine which of the midbrain dopamine projections may contribute to this effect, we next compared the impact of 6-ohda lesions of terminal fields, targeting the dorsal striatum, the lateral nucleus accumbens and the medial nucleus accumbens. |
2021-07-12 |
2023-08-13 |
rat |
| Susan Jone. De-mobilisation of NMDA receptors in midbrain dopamine neurons: a quantum of reward? The Journal of physiology. vol 599. issue 11. 2021-07-07. PMID:33769567. |
de-mobilisation of nmda receptors in midbrain dopamine neurons: a quantum of reward? |
2021-07-07 |
2023-08-13 |
Not clear |
| Qi Zhu, Xu-Xu Zhuang, Jia-Yue Chen, Ning-Ning Yuan, Yan Chen, Cui-Zan Cai, Jie-Qiong Tan, Huan-Xing Su, Jia-Hong L. Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 87. 2021-07-06. PMID:34038839. |
parkinson's disease (pd) is one of the most common neurodegenerative motor disorders, and is characterized by the presence of lewy bodies containing misfolded α-synuclein (α-syn) and by selective degeneration of midbrain dopamine neurons. |
2021-07-06 |
2023-08-13 |
Not clear |
| Malvin Jefri, Scott Bell, Huashan Peng, Nuwan Hettige, Gilles Maussion, Vincent Soubannier, Hanrong Wu, Heika Silveira, Jean-Francois Theroux, Luc Moquin, Xin Zhang, Zahia Aouabed, Jeyashree Krishnan, Liam A O'Leary, Lilit Antonyan, Ying Zhang, Vincent McCarty, Naguib Mechawar, Alain Gratton, Andreas Schuppert, Thomas M Durcan, Edward A Fon, Carl Erns. Stimulation of L-type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells. Stem cells translational medicine. vol 9. issue 6. 2021-07-01. PMID:32154672. |
stimulation of l-type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells. |
2021-07-01 |
2023-08-13 |
human |
| Malvin Jefri, Scott Bell, Huashan Peng, Nuwan Hettige, Gilles Maussion, Vincent Soubannier, Hanrong Wu, Heika Silveira, Jean-Francois Theroux, Luc Moquin, Xin Zhang, Zahia Aouabed, Jeyashree Krishnan, Liam A O'Leary, Lilit Antonyan, Ying Zhang, Vincent McCarty, Naguib Mechawar, Alain Gratton, Andreas Schuppert, Thomas M Durcan, Edward A Fon, Carl Erns. Stimulation of L-type calcium channels increases tyrosine hydroxylase and dopamine in ventral midbrain cells induced from somatic cells. Stem cells translational medicine. vol 9. issue 6. 2021-07-01. PMID:32154672. |
making high-quality dopamine (da)-producing cells for basic biological or small molecule screening studies is critical for the development of novel therapeutics for disorders of the ventral midbrain. |
2021-07-01 |
2023-08-13 |
human |
| Anne-Caroline Martel, Paul Apicell. Temporal processing in the striatum: Interplay between midbrain dopamine neurons and striatal cholinergic interneurons. The European journal of neuroscience. vol 53. issue 7. 2021-06-29. PMID:32281157. |
temporal processing in the striatum: interplay between midbrain dopamine neurons and striatal cholinergic interneurons. |
2021-06-29 |
2023-08-13 |
Not clear |
| Anne-Caroline Martel, Paul Apicell. Temporal processing in the striatum: Interplay between midbrain dopamine neurons and striatal cholinergic interneurons. The European journal of neuroscience. vol 53. issue 7. 2021-06-29. PMID:32281157. |
notably, the striatum and its dopamine (da) input from the ventral midbrain are considered to be central for timing on the scale of hundreds of milliseconds and seconds. |
2021-06-29 |
2023-08-13 |
Not clear |
| Kyoko Tossell, Rakesh A Dodhia, Benjamin Galet, Olga Tkachuk, Mark A Ungles. Tonic GABAergic inhibition, via GABA The European journal of neuroscience. vol 53. issue 6. 2021-06-29. PMID:33522050. |
tonic gabaergic inhibition, via gaba the activity of midbrain dopamine neurons is strongly regulated by fast synaptic inhibitory γ-aminobutyric acid (gaba)ergic inputs. |
2021-06-29 |
2023-08-13 |
Not clear |
| Martin Metzger, Rudieri Souza, Leandro B Lima, Debora Bueno, Luciano Gonçalves, Chemutai Sego, Jose Donato, Sara J Shammah-Lagnad. Habenular connections with the dopaminergic and serotonergic system and their role in stress-related psychiatric disorders. The European journal of neuroscience. vol 53. issue 1. 2021-06-28. PMID:31833616. |
so far, research on hb has focused on the role of the lhb in regulating midbrain dopamine release. |
2021-06-28 |
2023-08-13 |
Not clear |
| Atsushi Noritake, Taihei Ninomiya, Masaki Isod. Subcortical encoding of agent-relevant associative signals for adaptive social behavior in the macaque. Neuroscience and biobehavioral reviews. vol 125. 2021-06-28. PMID:33609569. |
such self-relevant and other-relevant associative signals are then integrated into a social utility signal, presumably at the level of midbrain dopamine neurons. |
2021-06-28 |
2023-08-13 |
monkey |
| Emilia Pascale, Giuseppina Divisato, Renata Palladino, Margherita Auriemma, Edward Faustine Ngalya, Massimiliano Caiazz. Noncoding RNAs and Midbrain DA Neurons: Novel Molecular Mechanisms and Therapeutic Targets in Health and Disease. Biomolecules. vol 10. issue 9. 2021-06-24. PMID:32899172. |
midbrain dopamine neurons have crucial functions in motor and emotional control and their degeneration leads to several neurological dysfunctions such as parkinson's disease, addiction, depression, schizophrenia, and others. |
2021-06-24 |
2023-08-13 |
Not clear |
| Emilia Pascale, Giuseppina Divisato, Renata Palladino, Margherita Auriemma, Edward Faustine Ngalya, Massimiliano Caiazz. Noncoding RNAs and Midbrain DA Neurons: Novel Molecular Mechanisms and Therapeutic Targets in Health and Disease. Biomolecules. vol 10. issue 9. 2021-06-24. PMID:32899172. |
despite advances in the understanding of specific altered proteins and coding genes, little is known about cumulative changes in the transcriptional landscape of noncoding genes in midbrain dopamine neurons. |
2021-06-24 |
2023-08-13 |
Not clear |
| Nabeel Ali, Amna Syeda, Tenzin Topgyal, Naseem Gaur, Asimul Isla. Parkinson's disease: A current perspectives on Parkinson's disease and key bioactive natural compounds as future potential drug candidates. Current drug targets. 2021-06-24. PMID:34165406. |
the hallmark of pd includes dopamine deficiency (neurotransmitter imbalance) due to the gradual loss of dopaminergic nerves in the substantia nigra in the midbrain. |
2021-06-24 |
2023-08-13 |
Not clear |
| Alberto F Cintrón-Colón, Gabriel Almeida-Alves, Alicia M Boynton, John M Spitsberge. GDNF synthesis, signaling, and retrograde transport in motor neurons. Cell and tissue research. vol 382. issue 1. 2021-06-23. PMID:32897420. |
gdnf was originally isolated from rat glial cell lines and identified as a neurotrophic factor with the ability to promote dopamine uptake within midbrain dopaminergic neurons. |
2021-06-23 |
2023-08-13 |
rat |
| Ewa Galaj, Guo-Hua Bi, Allamar Moore, Kai Chen, Yi He, Eliot Gardner, Zheng-Xiong X. Beta-caryophyllene inhibits cocaine addiction-related behavior by activation of PPARα and PPARγ: repurposing a FDA-approved food additive for cocaine use disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 4. 2021-06-23. PMID:33069159. |
we found that bcp is more effective in attenuation of cocaine-enhanced oicss than eicss, the former driven by optical activation of midbrain dopamine neurons in dat-cre mice. |
2021-06-23 |
2023-08-13 |
mouse |
| Maria F Fernandes, David Lau, Sandeep Sharma, Stephanie Fulto. Anxiety-like behavior in female mice is modulated by STAT3 signaling in midbrain dopamine neurons. Brain, behavior, and immunity. vol 95. 2021-06-23. PMID:33872705. |
anxiety-like behavior in female mice is modulated by stat3 signaling in midbrain dopamine neurons. |
2021-06-23 |
2023-08-13 |
mouse |
| Maria F Fernandes, David Lau, Sandeep Sharma, Stephanie Fulto. Anxiety-like behavior in female mice is modulated by STAT3 signaling in midbrain dopamine neurons. Brain, behavior, and immunity. vol 95. 2021-06-23. PMID:33872705. |
stat3 activation plays a pivotal role in the behavioral responses to the adiposity hormone leptin, including in midbrain dopamine (da) neurons where it mediates the influence of leptin to diminish physical activity and running reward in male mice. |
2021-06-23 |
2023-08-13 |
mouse |
| Miguel Skirzewski, Marie E Cronin, Ricardo Murphy, Wambura Fobbs, Alexxai V Kravitz, Andres Buonann. ErbB4 Null Mice Display Altered Mesocorticolimbic and Nigrostriatal Dopamine Levels as well as Deficits in Cognitive and Motivational Behaviors. eNeuro. vol 7. issue 3. 2021-06-18. PMID:32354758. |
whereas most studies on nrg1-erbb4 signaling have focused on gabaergic interneurons, erbb4 is also expressed by midbrain dopaminergic neurons where it modulates extracellular dopamine (da) levels. |
2021-06-18 |
2023-08-13 |
mouse |
| Silvia Papalini, Tom Beckers, Bram Vervlie. Dopamine: from prediction error to psychotherapy. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32451377. |
this narrative review focuses on the role of midbrain and prefrontal dopamine in novel safety learning and investigates possible pathways through which dopamine-based interventions could be used as an adjunct to improve both the response and the long-term effects of the therapy. |
2021-06-18 |
2023-08-13 |
Not clear |
| Austin T Akers, Skylar Y Cooper, Zachary J Baumgard, Gabriella P Casinelli, Alicia J Avelar, Brandon J Henderso. Upregulation of nAChRs and Changes in Excitability on VTA Dopamine and GABA Neurons Correlates to Changes in Nicotine-Reward-Related Behavior. eNeuro. vol 7. issue 5. 2021-06-18. PMID:32988984. |
here, we use male and female mice that contain α4-mcherry and α6-gfp nachr subunits to show that concentrations of nicotine sufficient to evoke reward-related behavior robustly upregulate α4* and α4α6* nachrs on midbrain dopamine (da) and gaba neurons. |
2021-06-18 |
2023-08-13 |
mouse |