| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Malou Dongelmans, Romain Durand-de Cuttoli, Claire Nguyen, Maxime Come, Etienne K Duranté, Damien Lemoine, Raphaël Brito, Tarek Ahmed Yahia, Sarah Mondoloni, Steve Didienne, Elise Bousseyrol, Bernadette Hannesse, Lauren M Reynolds, Nicolas Torquet, Deniz Dalkara, Fabio Marti, Alexandre Mourot, Jérémie Naudé, Philippe Faur. Chronic nicotine increases midbrain dopamine neuron activity and biases individual strategies towards reduced exploration in mice. Nature communications. vol 12. issue 1. 2021-11-29. PMID:34836948. |
chronic nicotine increases midbrain dopamine neuron activity and biases individual strategies towards reduced exploration in mice. |
2021-11-29 |
2023-08-13 |
mouse |
| Malou Dongelmans, Romain Durand-de Cuttoli, Claire Nguyen, Maxime Come, Etienne K Duranté, Damien Lemoine, Raphaël Brito, Tarek Ahmed Yahia, Sarah Mondoloni, Steve Didienne, Elise Bousseyrol, Bernadette Hannesse, Lauren M Reynolds, Nicolas Torquet, Deniz Dalkara, Fabio Marti, Alexandre Mourot, Jérémie Naudé, Philippe Faur. Chronic nicotine increases midbrain dopamine neuron activity and biases individual strategies towards reduced exploration in mice. Nature communications. vol 12. issue 1. 2021-11-29. PMID:34836948. |
using an intracranial self-stimulation reward-based foraging task, we investigated in mice the impact of chronic nicotine on midbrain dopamine neuron activity and its consequence on the trade-off between exploitation and exploration. |
2021-11-29 |
2023-08-13 |
mouse |
| Malou Dongelmans, Romain Durand-de Cuttoli, Claire Nguyen, Maxime Come, Etienne K Duranté, Damien Lemoine, Raphaël Brito, Tarek Ahmed Yahia, Sarah Mondoloni, Steve Didienne, Elise Bousseyrol, Bernadette Hannesse, Lauren M Reynolds, Nicolas Torquet, Deniz Dalkara, Fabio Marti, Alexandre Mourot, Jérémie Naudé, Philippe Faur. Chronic nicotine increases midbrain dopamine neuron activity and biases individual strategies towards reduced exploration in mice. Nature communications. vol 12. issue 1. 2021-11-29. PMID:34836948. |
our results reveal a key role of tonic midbrain dopamine in the exploration/exploitation trade-off and highlight a potential mechanism by which nicotine affects the exploration/exploitation balance and decision-making. |
2021-11-29 |
2023-08-13 |
mouse |
| Ke Xu, Jia Guo, Mingyue Ge, Jiangwen Yin, Han Zhang, Jieting Yin, Yan L. Effects of dopamine transporter changes in the ventral tegmental area of the midbrain on cognitive function in aged rats. Journal of chemical neuroanatomy. vol 117. 2021-11-26. PMID:34329711. |
effects of dopamine transporter changes in the ventral tegmental area of the midbrain on cognitive function in aged rats. |
2021-11-26 |
2023-08-13 |
rat |
| Ke Xu, Jia Guo, Mingyue Ge, Jiangwen Yin, Han Zhang, Jieting Yin, Yan L. Effects of dopamine transporter changes in the ventral tegmental area of the midbrain on cognitive function in aged rats. Journal of chemical neuroanatomy. vol 117. 2021-11-26. PMID:34329711. |
therefore, the purpose of this study was to investigate the relationship between changes in dopamine transporters in the ventral tegmental area (vta) of the midbrain and postoperative cognitive dysfunction in elderly rats. |
2021-11-26 |
2023-08-13 |
rat |
| Nora L Salaberry, Jorge Mendoz. The circadian clock in the mouse habenula is set by catecholamines. Cell and tissue research. 2021-11-24. PMID:34816282. |
anatomically, the hb projects to the midbrain dopamine (da) and serotonin (5-ht) systems, and it receives inputs from the forebrain, midbrain, and brainstem. |
2021-11-24 |
2023-08-13 |
mouse |
| Samaneh Mirzaei, Ketav Kulkarni, Kun Zhou, Peter J Crack, Marie-Isabel Aguilar, David I Finkelstein, John S Forsyth. Biomaterial Strategies for Restorative Therapies in Parkinson's Disease. ACS chemical neuroscience. vol 12. issue 22. 2021-11-23. PMID:34634903. |
parkinson's disease (pd) is a progressive neurological disorder, in which dopaminergic midbrain neurons degenerate, leading to dopamine depletion that is associated with neuronal death. |
2021-11-23 |
2023-08-13 |
Not clear |
| Avery F McGuirt, Michael R Post, Irena Pigulevskiy, David Sulzer, Ori J Lieberma. Coordinated Postnatal Maturation of Striatal Cholinergic Interneurons and Dopamine Release Dynamics in Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 16. 2021-11-19. PMID:33664134. |
its tonically active cholinergic interneuron (chi) is an integral regulator of the synaptic activity of other striatal neurons, as well as afferent axonal projections of midbrain dopamine (da) neurons; however, little is known about its development. |
2021-11-19 |
2023-08-13 |
mouse |
| Roberta Filograna, Seungmin Lee, Katarína Tiklová, Mara Mennuni, Viktor Jonsson, Markus Ringnér, Linda Gillberg, Elena Sopova, Oleg Shupliakov, Camilla Koolmeister, Lars Olson, Thomas Perlmann, Nils-Göran Larsso. Mitochondrial dysfunction in adult midbrain dopamine neurons triggers an early immune response. PLoS genetics. vol 17. issue 9. 2021-11-19. PMID:34570766. |
mitochondrial dysfunction in adult midbrain dopamine neurons triggers an early immune response. |
2021-11-19 |
2023-08-13 |
mouse |
| Roberta Filograna, Seungmin Lee, Katarína Tiklová, Mara Mennuni, Viktor Jonsson, Markus Ringnér, Linda Gillberg, Elena Sopova, Oleg Shupliakov, Camilla Koolmeister, Lars Olson, Thomas Perlmann, Nils-Göran Larsso. Mitochondrial dysfunction in adult midbrain dopamine neurons triggers an early immune response. PLoS genetics. vol 17. issue 9. 2021-11-19. PMID:34570766. |
dopamine (da) neurons of the midbrain are at risk to become affected by mitochondrial damage over time and mitochondrial defects have been frequently reported in parkinson's disease (pd) patients. |
2021-11-19 |
2023-08-13 |
mouse |
| Lindsey N Friend, Bridget Wu, Jeffrey G Edward. Acute cocaine exposure occludes long-term depression in ventral tegmental area GABA neurons. Neurochemistry international. vol 145. 2021-11-18. PMID:33617930. |
drugs of abuse increase midbrain dopamine cell activity and/or dopamine levels, and can alter endogenous vta glutamate plasticity, leading to addiction or dependence. |
2021-11-18 |
2023-08-13 |
mouse |
| Feng He, Pei Zhang, Qian Zhang, Guangjian Qi, Hongwei Cai, Tongxia Li, Ming Li, Jiazhen Lu, Jiaen Lin, Jie Ming, Bo Tia. Dopaminergic Projection from Ventral Tegmental Area to Substantia Nigra Pars Reticulata Mediates Chronic Social Defeat Stress-Induced Hypolocomotion. Molecular neurobiology. vol 58. issue 11. 2021-11-18. PMID:34382160. |
in mdd, the midbrain ventral tegmental area (vta) dopamine (da) neurons are closely related to regulate the information processing of reward, motivation, cognition, and aversion. |
2021-11-18 |
2023-08-13 |
mouse |
| Christopher J Knowlton, Tabea Ines Ziouziou, Niklas Hammer, Jochen Roeper, Carmen C Canavie. Inactivation mode of sodium channels defines the different maximal firing rates of conventional versus atypical midbrain dopamine neurons. PLoS computational biology. vol 17. issue 9. 2021-11-18. PMID:34534209. |
inactivation mode of sodium channels defines the different maximal firing rates of conventional versus atypical midbrain dopamine neurons. |
2021-11-18 |
2023-08-13 |
Not clear |
| Christopher J Knowlton, Tabea Ines Ziouziou, Niklas Hammer, Jochen Roeper, Carmen C Canavie. Inactivation mode of sodium channels defines the different maximal firing rates of conventional versus atypical midbrain dopamine neurons. PLoS computational biology. vol 17. issue 9. 2021-11-18. PMID:34534209. |
two subpopulations of midbrain dopamine (da) neurons are known to have different dynamic firing ranges in vitro that correspond to distinct projection targets: the originally identified conventional da neurons project to the dorsal striatum and the lateral shell of the nucleus accumbens, whereas an atypical da population with higher maximum firing frequencies projects to prefrontal regions and other limbic regions including the medial shell of nucleus accumbens. |
2021-11-18 |
2023-08-13 |
Not clear |
| Thomas C Jho. The rostromedial tegmental (RMTg) "brake" on dopamine and behavior: A decade of progress but also much unfinished work. Neuropharmacology. vol 198. 2021-11-17. PMID:34433088. |
between 2005 and 2009, several research groups identified a strikingly dense inhibitory input to midbrain dopamine neurons arising from a previously uncharted region posterior to the ventral tegmental area (vta). |
2021-11-17 |
2023-08-13 |
Not clear |
| Jacqueline M Tokarew, Daniel N El-Kodsi, Nathalie A Lengacher, Travis K Fehr, Angela P Nguyen, Bojan Shutinoski, Brian O'Nuallain, Ming Jin, Jasmine M Khan, Andy C H Ng, Juan Li, Qiubo Jiang, Mei Zhang, Liqun Wang, Rajib Sengupta, Kathryn R Barber, An Tran, Doo Soon Im, Steve Callaghan, David S Park, Stephanie Zandee, Xiajun Dong, Clemens R Scherzer, Alexandre Prat, Eve C Tsai, Masashi Takanashi, Nobutaka Hattori, Jennifer A Chan, Luigi Zecca, Andrew B West, Arne Holmgren, Lawrence Puente, Gary S Shaw, Gergely Toth, John M Woulfe, Peggy Taylor, Julianna J Tomlinson, Michael G Schlossmache. Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites. Acta neuropathologica. vol 141. issue 5. 2021-11-16. PMID:33694021. |
age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites. |
2021-11-16 |
2023-08-13 |
mouse |
| Aqilah M McCane, Meredyth A Wegener, Mojdeh Faraji, Maria T Rivera-Garcia, Kathryn G Wallin-Miller, Vincent D Costa, Bita Moghadda. Adolescent Dopamine Neurons Represent Reward Differently during Action and State Guided Learning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 45. 2021-11-14. PMID:34611024. |
both forms of learning, when associated with a rewarding outcome, rely on midbrain dopamine neurons in the ventral tegmental area (vta) and substantia nigra (sn). |
2021-11-14 |
2023-08-13 |
rat |
| Aqilah M McCane, Meredyth A Wegener, Mojdeh Faraji, Maria T Rivera-Garcia, Kathryn G Wallin-Miller, Vincent D Costa, Bita Moghadda. Adolescent Dopamine Neurons Represent Reward Differently during Action and State Guided Learning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 45. 2021-11-14. PMID:34611024. |
we find that, in adolescent male rats, reward-guided associative learning is encoded differently by midbrain dopamine neurons in each conditioning paradigm. |
2021-11-14 |
2023-08-13 |
rat |
| Fumihiko Ueno, Yusuke Iwata, Shinichiro Nakajima, Fernando Caravaggio, Jose M Rubio, Guillermo Horga, Clifford M Cassidy, Edgardo Torres-Carmona, Vincenzo de Luca, Sakiko Tsugawa, Shiori Honda, Sho Moriguchi, Yoshihiro Noda, Philip Gerretsen, Ariel Graff-Guerrer. Neuromelanin accumulation in patients with schizophrenia: A systematic review and meta-analysis. Neuroscience and biobehavioral reviews. 2021-11-12. PMID:34718049. |
although schizophrenia is associated with increased presynaptic dopamine function in the striatum, it remains unclear if neuromelanin levels, which are thought to serve as a biomarker for midbrain dopamine neuron function, are increased in patients with schizophrenia. |
2021-11-12 |
2023-08-13 |
Not clear |
| Kauê Machado Costa, Daniela Schenkel, Jochen Roepe. Sex-dependent alterations in behavior, drug responses and dopamine transporter expression in heterozygous DAT-Cre mice. Scientific reports. vol 11. issue 1. 2021-11-11. PMID:33558587. |
heterozygous mice that express cre-recombinase under the dopamine transporter promoter (dat-cre knock in mice, or ki) are widely used for targeting midbrain dopamine neurons, under the assumption that their constitutive physiology is not affected. |
2021-11-11 |
2023-08-13 |
mouse |