| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Juan F Morici, Lucia Ciccia, Gaël Malleret, Jay A Gingrich, Pedro Bekinschtein, Noelia V Weisstau. Serotonin 2a Receptor and Serotonin 1a Receptor Interact Within the Medial Prefrontal Cortex During Recognition Memory in Mice. Frontiers in pharmacology. vol 6. 2016-01-18. PMID:26779016. |
we also found that in the absence of 5-ht2ar signaling serotonin has a deleterious effect on recognition memory retrieval through the activation of 5-ht1ar in the medial prefrontal cortex. |
2016-01-18 |
2023-08-13 |
mouse |
| Renny Abraham, Ramakrishna Nirogi, Anil Shinde, Shantaveer Irupannanava. Low-dose prazosin in combination with 5-HT6 antagonist PRX-07034 has antipsychotic effects. Canadian journal of physiology and pharmacology. vol 93. issue 1. 2016-01-15. PMID:25429515. |
examination of the medial prefrontal cortex revealed that a combination of prx-07034 and prazosin reduced the dizocilpine-mediated increase of 5-ht. |
2016-01-15 |
2023-08-13 |
Not clear |
| María Eugenia Riveros, María Inés Forray, Fernando Torrealb. Infralimbic cortex activation and motivated arousal induce histamine release. Behavioural pharmacology. vol 26. issue 4. 2016-01-13. PMID:25746330. |
extracellular histamine and serotonin were measured by microdialysis of the medial prefrontal cortex in behaving rats in parallel with a picrotoxin microinjection into the infralimbic cortex. |
2016-01-13 |
2023-08-13 |
rat |
| S F Hassan, S Zumut, P G Burke, S McMullan, J L Cornish, A K Goodchil. Comparison of noradrenaline, dopamine and serotonin in mediating the tachycardic and thermogenic effects of methamphetamine in the ventral medial prefrontal cortex. Neuroscience. vol 295. 2016-01-13. PMID:25813709. |
comparison of noradrenaline, dopamine and serotonin in mediating the tachycardic and thermogenic effects of methamphetamine in the ventral medial prefrontal cortex. |
2016-01-13 |
2023-08-13 |
rat |
| S F Hassan, S Zumut, P G Burke, S McMullan, J L Cornish, A K Goodchil. Comparison of noradrenaline, dopamine and serotonin in mediating the tachycardic and thermogenic effects of methamphetamine in the ventral medial prefrontal cortex. Neuroscience. vol 295. 2016-01-13. PMID:25813709. |
rapidly distributing to forebrain regions to increase synaptic concentrations of three monoamines (dopamine (da), serotonin (5-ht) and noradrenaline (na)), the medial prefrontal cortex (mpfc) is important in meth-altered behavioral and psychological profiles. |
2016-01-13 |
2023-08-13 |
rat |
| Ling-Na Han, Li Zhang, Li-Bo Li, Yi-Na Sun, Yong Wang, Li Chen, Yuan Guo, Yu-Ming Zhang, Qiao-Jun Zhang, Jian Li. Activation of serotonin(2C) receptors in the lateral habenular nucleus increases the expression of depression-related behaviors in the hemiparkinsonian rat. Neuropharmacology. vol 93. 2016-01-01. PMID:25661701. |
intra-lhb injection of ro60-0175 decreased dopamine, 5-ht and noradrenaline levels in the medial prefrontal cortex, habenula, hippocampus and amygdala in sham-operated and the lesioned rats. |
2016-01-01 |
2023-08-13 |
rat |
| Yuichi Sakashita, Kenji Abe, Nobuyuki Katagiri, Toshie Kambe, Toshiaki Saitoh, Iku Utsunomiya, Yoshie Horiguchi, Kyoji Taguch. Effect of psilocin on extracellular dopamine and serotonin levels in the mesoaccumbens and mesocortical pathway in awake rats. Biological & pharmaceutical bulletin. vol 38. issue 1. 2015-12-15. PMID:25342005. |
in the present study, we examined the effects of systemically administered psilocin on extracellular dopamine and 5-ht concentrations in the ventral tegmental area (vta), nucleus accumbens, and medial prefrontal cortex of the dopaminergic pathway in awake rats using in vivo microdialysis. |
2015-12-15 |
2023-08-13 |
rat |
| Yuichi Sakashita, Kenji Abe, Nobuyuki Katagiri, Toshie Kambe, Toshiaki Saitoh, Iku Utsunomiya, Yoshie Horiguchi, Kyoji Taguch. Effect of psilocin on extracellular dopamine and serotonin levels in the mesoaccumbens and mesocortical pathway in awake rats. Biological & pharmaceutical bulletin. vol 38. issue 1. 2015-12-15. PMID:25342005. |
conversely, systemic administration of psilocin (10 mg/kg) significantly increased extracellular 5-ht levels in the medial prefrontal cortex of rats, but dopamine was decreased in this region. |
2015-12-15 |
2023-08-13 |
rat |
| Caroline A Browne, Joachim Hanke, Claudia Rose, Irene Walsh, Tara Foley, Gerard Clarke, Herbert Schwegler, John F Cryan, Deniz Yilmazer-Hank. Effect of acute swim stress on plasma corticosterone and brain monoamine levels in bidirectionally selected DxH recombinant inbred mouse strains differing in fear recall and extinction. Stress (Amsterdam, Netherlands). vol 17. issue 6. 2015-10-26. PMID:25117886. |
levels of noradrenaline, dopamine, and serotonin and their metabolites 3,4-dihydroxyphenyacetic acid (dopac), homovanillic acid (hva), and 5-hydroxyindoleacetic acid (5-hiaa) were studied in the amygdala, hippocampus, medial prefrontal cortex, striatum, hypothalamus and brainstem. |
2015-10-26 |
2023-08-13 |
mouse |
| Dan J Stei. Social anxiety disorder and the psychobiology of self-consciousness. Frontiers in human neuroscience. vol 9. 2015-10-07. PMID:26441590. |
a number of investigations of sad have highlighted altered activity in the medial prefrontal cortex (mpfc; involved in self-representation), insula (involved in interoceptive processing), and other structures that play a role in bodily self-consciousness, as well as the potential value of interventions such as selective serotonin reuptake inhibitors (ssri) and self-focused reappraisal in normalizing such changes. |
2015-10-07 |
2023-08-13 |
Not clear |
| Yan Ping Hui, Tao Wang, Ling Na Han, Li Bo Li, Yi Na Sun, Jian Liu, Hong Fei Qiao, Qiao Jun Zhan. Anxiolytic effects of prelimbic 5-HT(1A) receptor activation in the hemiparkinsonian rat. Behavioural brain research. vol 277. 2015-09-08. PMID:24906197. |
this study sought to assess whether unilateral lesions of the medial forebrain bundle (mfb) using 6-hydroxydopamine in rats are able to induce anxiety-like behaviors, the role of serotonin-1a (5-ht1a) receptors of the prelimbic (prl) sub-region of ventral medial prefrontal cortex in the regulation of these behaviors, the density of 5-ht neurons in the dorsal raphe nucleus (drn) and co-localization of 5-ht1a receptor and neuronal glutamate transporter eaac1-immunoreactive (eaac1-ir) cells in the prl. |
2015-09-08 |
2023-08-13 |
rat |
| Luciana Romina Frick, Micaela Bernardez-Vidal, Christian Hocht, Bonifacio Silvano Zanutto, Maximiliano Rapanell. Dual role of serotonin in the acquisition and extinction of reward-driven learning: involvement of 5-HT1A, 5-HT2A and 5-HT3 receptors. Behavioural brain research. vol 277. 2015-09-08. PMID:24949809. |
given that the major serotonergic circuit in the rat brain comprises the dorsal raphe nuclei and the medial prefrontal cortex (mpfc), and because the latter structure is involved in the control of complex behaviors and expresses 1a (5-ht1a), 2a (5-ht2a), and 3 (5-ht3) receptors, the aim was to study the role of 5-ht and of these receptors in the acquisition and extinction of a reward-dependent operant conditioning task. |
2015-09-08 |
2023-08-13 |
rat |
| Aloke K Dutta, Soumava Santra, Horrick Sharma, Chandrashekhar Voshavar, Liping Xu, Omar Mabrouk, Tamara Antonio, Maarten E A Reit. Pharmacological and behavioral characterization of D-473, an orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters. PloS one. vol 9. issue 11. 2015-07-20. PMID:25427177. |
microdialysis experiment demonstrated that systemic administration of d-473 elevated extracellular level of the three monoamines da, 5-ht, and ne efficaciously in the dorsal lateral striatum (dls) and the medial prefrontal cortex (mpfc) area, indicating in vivo blockade of all three monoamine transporters by d-473. |
2015-07-20 |
2023-08-13 |
human |
| Aki Takahashi, Ray X Lee, Takuji Iwasato, Shigeyoshi Itohara, Hiroshi Arima, Bernhard Bettler, Klaus A Miczek, Tsuyoshi Koid. Glutamate input in the dorsal raphe nucleus as a determinant of escalated aggression in male mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 16. 2015-07-16. PMID:25904796. |
finally, 5-ht release was increased within the drn and also in the medial prefrontal cortex when animals were provoked by social instigation, and during escalated aggression after social instigation, but this increase in 5-ht release was not observed when animals were engaged in species-typical aggression. |
2015-07-16 |
2023-08-13 |
mouse |
| Isabel M Quadros, Lara S Hwa, Akiko Shimamoto, Julia Carlson, Joseph F DeBold, Klaus A Micze. Prevention of alcohol-heightened aggression by CRF-R1 antagonists in mice: critical role for DRN-PFC serotonin pathway. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 12. 2015-07-10. PMID:24917195. |
the serotonin (5-ht) pathway from the dorsal raphe nucleus (drn) to the medial prefrontal cortex (mpfc) by crf-r1 was investigated as a possible target for the prevention of alcohol-heightened aggressive behavior. |
2015-07-10 |
2023-08-13 |
mouse |
| Ming Lei, Lu Luo, Shi-Qi Ma, Yan Zhang, Xi-Hong Wu, Liang L. [Behavioral and neurobiological abnormalities induced by social isolation as a useful animal model of schizophrenia]. Sheng li xue bao : [Acta physiologica Sinica]. vol 65. issue 1. 2015-05-16. PMID:23426521. |
moreover, social isolation causes changes of neurotransmitters, such as the increase of dopamine in the nucleus accumbens, the amygdala and other brain regions in the limbic system, the decrease of dopamine in medial prefrontal cortex, the decrease of 5-ht in the nucleus accumbens and the hippocampus, and changes of glutamine in the prefrontal cortex. |
2015-05-16 |
2023-08-12 |
rat |
| Susumu Jitsuki, Fukuko Kimura, Toshiya Funabashi, Takuya Takahashi, Dai Mitsushim. Sex-specific 24-h profile of extracellular serotonin levels in the medial prefrontal cortex. Brain research. vol 1260. 2015-03-30. PMID:19368844. |
sex-specific 24-h profile of extracellular serotonin levels in the medial prefrontal cortex. |
2015-03-30 |
2023-08-12 |
rat |
| Anne Klomp, Ralph Hamelink, Matthijs Feenstra, Damiaan Denys, Liesbeth Renema. Increased response to a 5-HT challenge after discontinuation of chronic serotonin uptake inhibition in the adult and adolescent rat brain. PloS one. vol 9. issue 6. 2015-02-12. PMID:24937739. |
we therefore examined the chronic effects of fluoxetine on extracellular 5-ht and dopamine concentrations in the medial prefrontal cortex and studied their responsiveness to an acute 5-ht challenge after a one-week washout period, both in adolescent and adult rats. |
2015-02-12 |
2023-08-13 |
rat |
| Anne Klomp, Ralph Hamelink, Matthijs Feenstra, Damiaan Denys, Liesbeth Renema. Increased response to a 5-HT challenge after discontinuation of chronic serotonin uptake inhibition in the adult and adolescent rat brain. PloS one. vol 9. issue 6. 2015-02-12. PMID:24937739. |
no apparent age-at-treatment effects on extracellular monoamine concentrations in the medial prefrontal cortex were detected, but age-related differences in 5-ht transmission further down-stream or in the recovery processes cannot be ruled out. |
2015-02-12 |
2023-08-13 |
rat |
| Aki Takahashi, Isabel M Quadros, Rosa M M de Almeida, Klaus A Micze. Behavioral and pharmacogenetics of aggressive behavior. Current topics in behavioral neurosciences. vol 12. 2015-01-20. PMID:22297576. |
also, the local administration of a drug using the intracranial microinjection technique has shown that activation of specific subtypes of 5-ht receptors (5-ht1a and 5-ht1b) in mesocorticolimbic areas can reduce species-typical and other aggressive behaviors, but the same receptors in the medial prefrontal cortex or septal area promote escalated forms of aggression. |
2015-01-20 |
2023-08-12 |
mouse |