| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B D Karrenbauer, C P Müller, Y J Ho, R Spanagel, J P Huston, R K W Schwarting, C R Pawla. Time-dependent in-vivo effects of interleukin-2 on neurotransmitters in various cortices: relationships with depressive-related and anxiety-like behaviour. Journal of neuroimmunology. vol 237. issue 1-2. 2011-10-17. PMID:21726905. |
il-2 lastingly reduced extracellular 5-ht levels in the medial prefrontal (-75%), occipital (-70%), and temporal cortices (-45%), whereas dopamine was only moderately reduced in the medial prefrontal cortex. |
2011-10-17 |
2023-08-12 |
Not clear |
| Jason M Dwyer, Brian J Platt, Stacey J Sukoff Rizzo, Claudine M Pulicicchio, Caitlin Wantuch, Mei-Yi Zhang, Terri Cummons, Liza Leventhal, Corey N Bender, Jean Zhang, Dianne Kowal, Shendi Lu, S Johannes R Rajarao, Deborah L Smith, Adam D Shilling, Jianyao Wang, John Butera, Lynn Resnick, Sharon Rosenzweig-Lipson, Lee E Schechter, Chad E Beye. Preclinical characterization of BRL 44408: antidepressant- and analgesic-like activity through selective alpha2A-adrenoceptor antagonism. The international journal of neuropsychopharmacology. vol 13. issue 9. 2011-09-01. PMID:20047711. |
consistent with presynaptic autoreceptor antagonism and tonic regulation of neurotransmitter release, acute administration of brl 44408 elevated extracellular concentrations of norepinephrine and dopamine, but not serotonin, in the medial prefrontal cortex. |
2011-09-01 |
2023-08-12 |
rat |
| Robin L Aupperle, Lakshmi Ravindran, Dharol Tankersley, Taru Flagan, Nathan R Stein, Alan N Simmons, Murray B Stein, Martin P Paulu. Pregabalin influences insula and amygdala activation during anticipation of emotional images. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 7. 2011-08-10. PMID:21430645. |
previous functional magnetic resonance imaging (fmri) studies indicate that selective serotonin reuptake inhibitors and benzodiazepines attenuate amygdala, insula, and medial prefrontal cortex activation during anticipation and emotional processing in healthy controls. |
2011-08-10 |
2023-08-12 |
Not clear |
| Qiao Jun Zhang, Li Bo Li, Xiao Lin Niu, Jian Liu, Zhen Hua Gui, Jian Jun Feng, Umar Ali, Yan Pin Hui, Zhong Heng W. The pyramidal neurons in the medial prefrontal cortex show decreased response to 5-hydroxytryptamine-3 receptor stimulation in a rodent model of Parkinson's disease. Brain research. vol 1384. 2011-07-19. PMID:21291871. |
in the present study, effect of sr 57227a, a selective 5-hydroxytryptamine-3 (5-ht(3)) receptor agonist, on the firing activity of pyramidal neurons in the medial prefrontal cortex (mpfc) was studied in normal rats and rats with 6-hydroxydopamine lesions of the substantia nigra pars compacta by using extracellular recording. |
2011-07-19 |
2023-08-12 |
rat |
| Shin-ichi Kimura, Hiroko Togashi, Machiko Matsumoto, Taito Shiozawa, Junko Ishida, Satomi Kano, Atsuko Ohashi, Shyhei Ishikawa, Taku Yamaguchi, Mitsuhiro Yoshioka, Keiichi Shimamur. Serotonin(1A) receptor-mediated synaptic response in the rat medial prefrontal cortex is altered by early life stress: in vivo and in vitro electrophysiological studies. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 31. issue 1. 2011-06-21. PMID:21404951. |
serotonin(1a) receptor-mediated synaptic response in the rat medial prefrontal cortex is altered by early life stress: in vivo and in vitro electrophysiological studies. |
2011-06-21 |
2023-08-12 |
rat |
| V Valentini, R Frau, F Bordi, F Borsini, G Di Chiar. A microdialysis study of ST1936, a novel 5-HT6 receptor agonist. Neuropharmacology. vol 60. issue 4. 2011-05-12. PMID:21185318. |
here we report the effect of st1936 (5-10-20 mg/kg/ip) on dialysate da, na and 5-ht in the medial prefrontal cortex (pfcx) and in the shell and core of the nucleus accumbens (nac). |
2011-05-12 |
2023-08-12 |
Not clear |
| Keiko Ohoyama, Satoshi Yamamura, Tatsuya Hamaguchi, Masanori Nakagawa, Eishi Motomura, Takashi Shiroyama, Hisashi Tanii, Motohiro Okad. Effect of novel atypical antipsychotic, blonanserin, on extracellular neurotransmitter level in rat prefrontal cortex. European journal of pharmacology. vol 653. issue 1-3. 2011-05-02. PMID:21147094. |
to clarify the mechanisms of action of blonanserin, an atypical antipsychotic drug, we studied the effects of systemic administration of blonanserin and risperidone on extracellular levels of norepinephrine, dopamine, serotonin, gaba and glutamate in the medial prefrontal cortex using microdialysis, and neuronal firing in the ventral tegmental area, locus coeruleus, dorsal raphe nucleus and mediodorsal thalamic nucleus using radiotelemetry. |
2011-05-02 |
2023-08-12 |
rat |
| Yuji Kitaichi, Takeshi Inoue, Shin Nakagawa, Shuken Boku, Aya Kakuta, Takeshi Izumi, Tsukasa Koyam. Sertraline increases extracellular levels not only of serotonin, but also of dopamine in the nucleus accumbens and striatum of rats. European journal of pharmacology. vol 647. issue 1-3. 2011-04-01. PMID:20816814. |
we examined effects of sertraline, fluvoxamine, and paroxetine on extracellular serotonin, dopamine, and noradrenaline levels in the medial prefrontal cortex, nucleus accumbens and striatum of rats using in vivo microdialysis. |
2011-04-01 |
2023-08-12 |
rat |
| Hans Rollema, Gary G Wilson, Theodore C Lee, Joost H A Folgering, Gunnar Fli. Effect of co-administration of varenicline and antidepressants on extracellular monoamine concentrations in rat prefrontal cortex. Neurochemistry international. vol 58. issue 1. 2011-03-31. PMID:21056607. |
given the important role attributed to cortical monoamine release in serotonin syndrome as well as antidepressant activity, the effects on extracellular monoamine concentrations were measured in the medial prefrontal cortex. |
2011-03-31 |
2023-08-12 |
rat |
| Anton N M Schoffelmeer, Benjamin Drukarch, Taco J De Vries, François Hogenboom, Dustin Schetters, Tommy Patti. Insulin modulates cocaine-sensitive monoamine transporter function and impulsive behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 4. 2011-03-30. PMID:21273413. |
similar insulin effects were observed on the release of [(3)h]norepinephrine in nucleus accumbens slices, but not on that of [(3)h]serotonin, and were also apparent in medial prefrontal cortex slices. |
2011-03-30 |
2023-08-12 |
rat |
| A Beyeler, N Kadiri, S Navailles, M Ben Boujema, F Gonon, C Le Moine, C Gross, P De Deurwaerdèr. Stimulation of serotonin2C receptors elicits abnormal oral movements by acting on pathways other than the sensorimotor one in the rat basal ganglia. Neuroscience. vol 169. issue 1. 2011-03-04. PMID:20447448. |
in the present study, we combined behavioral, immunohistochemical and extracellular single-cell recordings approaches in rats to investigate the effect of the 5-ht(2c) agonist ro-60-0175 respectively on orofacial dyskinesia, the expression of the marker of neuronal activity c-fos in basal ganglia and the electrophysiological activity of substantia nigra pars reticulata (snr) neuron connected to the orofacial motor cortex (ofmc) or the medial prefrontal cortex (mpfc). |
2011-03-04 |
2023-08-12 |
rat |
| Kathryn A Cunningham, Marcy J Bubar, Noelle C Anastasi. The serotonin 5-HT2C receptor in medial prefrontal cortex exerts rheostatic control over the motivational salience of cocaine-associated cues: new observations from preclinical animal research. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 12. 2011-02-16. PMID:20948510. |
the serotonin 5-ht2c receptor in medial prefrontal cortex exerts rheostatic control over the motivational salience of cocaine-associated cues: new observations from preclinical animal research. |
2011-02-16 |
2023-08-12 |
Not clear |
| Yuefeng Lu, Kimberly L Simpson, Kristin J Weaver, Rick C S Li. Coexpression of serotonin and nitric oxide in the raphe complex: cortical versus subcortical circuit. Anatomical record (Hoboken, N.J. : 2007). vol 293. issue 11. 2011-02-10. PMID:20734426. |
our data demonstrated that: (1) a significant number of raphe-cortical projecting neurons was identified not only in the midline subgroup of dorsal raphe (b6, 7) but also in the median raphe (b8), as well as in the supralemniscal nucleus (b9); (2) serotonergic cortical projecting neurons from these three raphe nuclei exhibited a high (>80%) percentage of coexpression with nnos immunoreactivity; (3) similarly, serotonin transporter immunoreactive fibers in the medial prefrontal cortex were also double-labeled with nnos immunoreactivity; (4) in contrast, the descending spinal cord projecting raphe nuclei revealed only tph but not nnos immunoreactivity. |
2011-02-10 |
2023-08-12 |
Not clear |
| Agnieszka Nikiforuk, Piotr Popik, Karla U Drescher, Marcel van Gaalen, Ana-Lucia Relo, Mario Mezler, Gerard Marek, Hans Schoemaker, Gerhard Gross, Anton Bespalo. Effects of a positive allosteric modulator of group II metabotropic glutamate receptors, LY487379, on cognitive flexibility and impulsive-like responding in rats. The Journal of pharmacology and experimental therapeutics. vol 335. issue 3. 2011-02-03. PMID:20739457. |
ly487379 significantly enhanced extracellular norepinephrine and serotonin levels in the medial prefrontal cortex. |
2011-02-03 |
2023-08-12 |
rat |
| Marzena Ferdyn-Drosik, Przemysław Nowak, Kamila Bojanek, Michał Bałasz, Jacek Kasperski, Dariusz Skaba, Rafał Muchacki, Richard M Kostrzew. Neonatal DSP-4 treatment impairs 5-HT(1B) receptor reactivity in adult rats. Behavioral and biochemical studies. Pharmacological reports : PR. vol 62. issue 4. 2011-01-12. PMID:20885001. |
cp 94,253 significantly attenuated 5-ht synthesis in the medial prefrontal cortex (mpfc) of control rats, and sb 216641 (n-{3-[3-(dimethylamino)ethoxy]-4-methoxyphenyl}-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carboxamide hydrochloride) (4.0 mg/kg; 5-ht(1b) antagonist) was able to antagonize this effect. |
2011-01-12 |
2023-08-12 |
rat |
| Z H Gui, Q J Zhang, J Liu, U Ali, L B Li, Y Wang, T Wang, L Chen, C Hou, L L Fa. In vivo modulation of the firing activity of putative slow- and fast-spiking interneurons in the medial prefrontal cortex by 5-HT3 receptors in 6-hydroxydopamine-induced Parkinsonian rats. Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20576497. |
in the present study, we examined changes in the firing rate and firing pattern of putative slow-spiking (ss) and fast-spiking (fs) interneurons in medial prefrontal cortex (mpfc) and the effect of 5-hydroxytryptamine-3 (5-ht(3)) receptor agonist sr 57227a on the neuronal firing in rats with 6-hydroxydopamine lesions of the substantia nigra pars compacta (snc) by using extracellular recording. |
2010-12-16 |
2023-08-12 |
rat |
| Nathan S Pentkowski, Felicia D Duke, Suzanne M Weber, Lara A Pockros, Andrew P Teer, Elizabeth C Hamilton, Kenneth J Thiel, Janet L Neisewande. Stimulation of medial prefrontal cortex serotonin 2C (5-HT(2C)) receptors attenuates cocaine-seeking behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 10. 2010-12-06. PMID:20520599. |
stimulation of medial prefrontal cortex serotonin 2c (5-ht(2c)) receptors attenuates cocaine-seeking behavior. |
2010-12-06 |
2023-08-12 |
rat |
| Nathan S Pentkowski, Felicia D Duke, Suzanne M Weber, Lara A Pockros, Andrew P Teer, Elizabeth C Hamilton, Kenneth J Thiel, Janet L Neisewande. Stimulation of medial prefrontal cortex serotonin 2C (5-HT(2C)) receptors attenuates cocaine-seeking behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 10. 2010-12-06. PMID:20520599. |
to further elucidate the function of these receptors in addiction-like processes, this study examined the effects of microinfusing the 5-ht(2c)r agonist mk212 (0, 10, 30, 100 ng/side/0.2 microl) into the medial prefrontal cortex (mpfc) on cocaine self-administration and reinstatement of extinguished cocaine-seeking behavior. |
2010-12-06 |
2023-08-12 |
rat |
| Eleonora Calcagno, Roberto W Invernizz. Strain-dependent serotonin neuron feedback control: role of serotonin 2C receptors. Journal of neurochemistry. vol 114. issue 6. 2010-10-19. PMID:20584103. |
systemic and/or intra-dr infusion of the serotonin(2c) receptor antagonist 6-chloro-5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]-5-pyridyl]carbamoyl]-indoline (1 mg/kg and 0.1 μm, respectively) enhanced citalopram's effect on extracellular serotonin in the dr and medial prefrontal cortex and abolished the rise of gaba in the dr of dba/2 mice but had no effect in c57bl/6 mice. |
2010-10-19 |
2023-08-12 |
mouse |
| Peter Holm, Anders Ettrup, Anders B Klein, Martin A Santini, Mona El-Sayed, Anders B Elvang, Tine B Stensbøl, Jens D Mikkelsen, Gitte M Knudsen, Susana Azna. Plaque deposition dependent decrease in 5-HT2A serotonin receptor in AbetaPPswe/PS1dE9 amyloid overexpressing mice. Journal of Alzheimer's disease : JAD. vol 20. issue 4. 2010-10-12. PMID:20413853. |
[3h]-mdl100907, [3h]-escitalopram, and [11c]-pib autoradiography was performed for measuring 5-ht2a receptor, serotonin transporter (sert), and abeta plaque levels in medial prefrontal cortex (mpfc), prefrontal cortex (pfc), frontoparietal cortex (fpc), dorsal and ventral hippocampus, and somatosensory cortex. |
2010-10-12 |
2023-08-12 |
mouse |