| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xavier López-Gil, Laura Jiménez-Sánchez, Tamara Romón, Leticia Campa, Francesc Artigas, Albert Adel. Importance of inter-hemispheric prefrontal connection in the effects of non-competitive NMDA receptor antagonists. The international journal of neuropsychopharmacology. vol 15. issue 7. 2012-12-11. PMID:21733285. |
the unilateral perfusion of 1 μm tetrodotoxin in the medial prefrontal cortex reduced increases of serotonin in both hemispheres, the expression of c-fos in the contralateral side, and stereotypy scores after systemic nmda antagonists. |
2012-12-11 |
2023-08-12 |
Not clear |
| Xavier López-Gil, Laura Jiménez-Sánchez, Tamara Romón, Leticia Campa, Francesc Artigas, Albert Adel. Importance of inter-hemispheric prefrontal connection in the effects of non-competitive NMDA receptor antagonists. The international journal of neuropsychopharmacology. vol 15. issue 7. 2012-12-11. PMID:21733285. |
our results support the hypothesis that a bilateral impairment of cortical inhibition in the medial prefrontal cortex is needed for non-competitive nmda antagonists to induce the state of pyramidal cell hyperactivity and concurrent efflux of serotonin. |
2012-12-11 |
2023-08-12 |
Not clear |
| J Kehr, S Yoshitake, S Ijiri, E Koch, M Nöldner, T Yoshitak. Ginkgo biloba leaf extract (EGb 761®) and its specific acylated flavonol constituents increase dopamine and acetylcholine levels in the rat medial prefrontal cortex: possible implications for the cognitive enhancing properties of EGb 761®. International psychogeriatrics. vol 24 Suppl 1. 2012-11-28. PMID:22784425. |
the aim of this study was to examine the effect of repeated oral administration of egb 761® and some of its characteristic constituents on extracellular levels of dopamine (da), noradrenaline (na), serotonin (5-ht), acetylcholine (ach) and the metabolites 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva) and 5-hydroxyindoleacetic acid (5-hiaa) in the medial prefrontal cortex (mpfc) of awake rats by use of in vivo microdialysis technique. |
2012-11-28 |
2023-08-12 |
rat |
| Masatoshi Nagano, Mingyan Liu, Hirofumi Inagaki, Tomoyuki Kawada, Hidenori Suzuk. Early intervention with fluoxetine reverses abnormalities in the serotonergic system and behavior of rats exposed prenatally to dexamethasone. Neuropharmacology. vol 63. issue 2. 2012-11-19. PMID:22710353. |
in the present study, we found abnormalities in serotonin (5-ht) signaling, including decreased expression of 5-ht(1a) receptor (5-ht(1a)-r) mrna in the medial prefrontal cortex (mpfc) and 5-ht content in the hippocampus at postnatal week (pw) 4. |
2012-11-19 |
2023-08-12 |
rat |
| Laia Lladó-Pelfort, Noemí Santana, Valentina Ghisi, Francesc Artigas, Pau Celad. 5-HT1A receptor agonists enhance pyramidal cell firing in prefrontal cortex through a preferential action on GABA interneurons. Cerebral cortex (New York, N.Y. : 1991). vol 22. issue 7. 2012-11-13. PMID:21893679. |
5-ht(1a) receptors (5-ht1ar) are expressed by pyramidal and γ-aminobutyric acidergic (gabaergic) neurons in medial prefrontal cortex (mpfc). |
2012-11-13 |
2023-08-12 |
rat |
| Daniel Avesar, Allan T Gulledg. Selective serotonergic excitation of callosal projection neurons. Frontiers in neural circuits. vol 6. 2012-10-02. PMID:22454619. |
we tested the serotonergic responsiveness of layer 5 pyramidal neurons (l5pns) in the mouse medial prefrontal cortex (mpfc), and found three distinct response types: long-lasting 5-ht(1a) (1a) receptor-dependent inhibitory responses (84% of l5pns), 5-ht(2a) (2a) receptor-dependent excitatory responses (9%), and biphasic responses in which 2a-dependent excitation followed brief inhibition (5%). |
2012-10-02 |
2023-08-12 |
mouse |
| Patrick M Fisher, Julie C Price, Carolyn C Meltzer, Eydie L Moses-Kolko, Carl Becker, Sarah L Berga, Ahmad R Harir. Medial prefrontal cortex serotonin 1A and 2A receptor binding interacts to predict threat-related amygdala reactivity. Biology of mood & anxiety disorders. vol 1. issue 1. 2012-10-02. PMID:22738071. |
medial prefrontal cortex serotonin 1a and 2a receptor binding interacts to predict threat-related amygdala reactivity. |
2012-10-02 |
2023-08-12 |
human |
| Olivia Frånberg, Monica M Marcus, Torgny H Svensso. Involvement of 5-HT2A receptor and α2-adrenoceptor blockade in the asenapine-induced elevation of prefrontal cortical monoamine outflow. Synapse (New York, N.Y.). vol 66. issue 7. 2012-09-17. PMID:22362425. |
previous results show that asenapine, both systemically and locally, increases dopamine, noradrenaline, and serotonin release in the medial prefrontal cortex (mpfc), and that the increased dopamine release largely depends on an intracortical action. |
2012-09-17 |
2023-08-12 |
rat |
| Pierre-Eric Lutz, Amynah A Pradhan, Celia Goeldner, Brigitte L Kieffe. Sequential and opposing alterations of 5-HT(1A) receptor function during withdrawal from chronic morphine. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 21. issue 11. 2012-08-01. PMID:21402471. |
using [(35)s]gtpγs autoradiography in mice, we show that 5-ht(1a) receptor function is enhanced by chronic morphine treatment in the medial prefrontal cortex, and decreased in dorsal raphe nucleus one week later, two regions involved in emotional processing. |
2012-08-01 |
2023-08-12 |
mouse |
| Alexander K Converse, Yves Aubert, Mohammed Farhoud, Jamey P Weichert, Ian J Rowland, Nicole M Ingrisano, Kelly A Allers, Bernd Sommer, David H Abbot. Positron emission tomography assessment of 8-OH-DPAT-mediated changes in an index of cerebral glucose metabolism in female marmosets. NeuroImage. vol 60. issue 1. 2012-07-03. PMID:22233732. |
we hypothesized that chronic treatment with the 5-ht(1a) agonist 8-oh-dpat would alter the glucose metabolism index in dorsal raphe (dr), medial prefrontal cortex (mpfc), medial preoptic area of hypothalamus (mpoa), ventromedial nucleus of hypothalamus (vmh), and field ca1 of hippocampus. |
2012-07-03 |
2023-08-12 |
human |
| Yu-Lung Lin, Shu-Yi Lin, Sabrina Wan. Prenatal lipopolysaccharide exposure increases anxiety-like behaviors and enhances stress-induced corticosterone responses in adult rats. Brain, behavior, and immunity. vol 26. issue 3. 2012-06-22. PMID:22198119. |
dopamine (da) in the nucleus accumbens and serotonin (5-ht) in the medial prefrontal cortex and the hippocampus were significantly reduced in lps rats. |
2012-06-22 |
2023-08-12 |
rat |
| A Mørk, A Pehrson, L T Brennum, S Møller Nielsen, H Zhong, A B Lassen, S Miller, L Westrich, N J Boyle, C Sánchez, C W Fischer, N Liebenberg, G Wegener, C Bundgaard, S Hogg, B Bang-Andersen, T Bryan Stensbø. Pharmacological effects of Lu AA21004: a novel multimodal compound for the treatment of major depressive disorder. The Journal of pharmacology and experimental therapeutics. vol 340. issue 3. 2012-05-04. PMID:22171087. |
in rat microdialysis experiments, lu aa21004 (2.5-10.0 mg/kg s.c.) increased extracellular 5-ht, dopamine, and noradrenaline in the medial prefrontal cortex and ventral hippocampus. |
2012-05-04 |
2023-08-12 |
human |
| Davide Quarta, Charles H Larg. Effects of lamotrigine on PCP-evoked elevations in monoamine levels in the medial prefrontal cortex of freely moving rats. Journal of psychopharmacology (Oxford, England). vol 25. issue 12. 2012-04-26. PMID:21041417. |
we studied pcp-evoked overflow of noradrenaline, dopamine and serotonin in the medial prefrontal cortex of awake rats using microdialysis. |
2012-04-26 |
2023-08-12 |
rat |
| Andreas Hahn, Wolfgang Wadsak, Christian Windischberger, Pia Baldinger, Anna S Höflich, Jan Losak, Lukas Nics, Cécile Philippe, Georg S Kranz, Christoph Kraus, Markus Mitterhauser, Georgios Karanikas, Siegfried Kasper, Rupert Lanzenberge. Differential modulation of the default mode network via serotonin-1A receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 7. 2012-04-20. PMID:22308408. |
in the frontal part of the dmn, a negative association was found between the dorsal medial prefrontal cortex and local 5-ht(1a) inhibition. |
2012-04-20 |
2023-08-12 |
human |
| Sonny K H Tan, Henrike Hartung, Veerle Visser-Vandewalle, Harry W M Steinbusch, Yasin Temel, Trevor Shar. A combined in vivo neurochemical and electrophysiological analysis of the effect of high-frequency stimulation of the subthalamic nucleus on 5-HT transmission. Experimental neurology. vol 233. issue 1. 2012-03-25. PMID:21925498. |
bilateral stn hfs decreased (by up to 25%) extracellular levels of 5-ht in both striatum and medial prefrontal cortex of anesthetized rats. |
2012-03-25 |
2023-08-12 |
rat |
| Sonny K H Tan, Henrike Hartung, Veerle Visser-Vandewalle, Harry W M Steinbusch, Yasin Temel, Trevor Shar. A combined in vivo neurochemical and electrophysiological analysis of the effect of high-frequency stimulation of the subthalamic nucleus on 5-HT transmission. Experimental neurology. vol 233. issue 1. 2012-03-25. PMID:21925498. |
stn hfs also decreased extracellular 5-ht in the medial prefrontal cortex of freely moving rats. |
2012-03-25 |
2023-08-12 |
rat |
| Jalal Solati, Ali-Akbar Salari, Amir Bakhtiar. 5HT(1A) and 5HT(1B) receptors of medial prefrontal cortex modulate anxiogenic-like behaviors in rats. Neuroscience letters. vol 504. issue 3. 2012-03-15. PMID:21982809. |
5ht(1a) and 5ht(1b) receptors of medial prefrontal cortex modulate anxiogenic-like behaviors in rats. |
2012-03-15 |
2023-08-12 |
rat |
| Xiao Han, Weiwen Wang, Feng Shao, Nanxin L. Isolation rearing alters social behaviors and monoamine neurotransmission in the medial prefrontal cortex and nucleus accumbens of adult rats. Brain research. vol 1385. 2012-02-14. PMID:21338587. |
isolation-reared rats also manifested increased dopamine and serotonin levels in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) as well as an increase in serotonin turnover in the nac. |
2012-02-14 |
2023-08-12 |
rat |
| Z H Gui, Q J Zhang, J Liu, L Zhang, U Ali, C Hou, L L Fan, Y N Sun, Z H Wu, Y P Hu. Unilateral lesion of the nigrostriatal pathway decreases the response of fast-spiking interneurons in the medial prefrontal cortex to 5-HT1A receptor agonist and expression of the receptor in parvalbumin-positive neurons in the rat. Neurochemistry international. vol 59. issue 5. 2012-01-12. PMID:21693147. |
in the present study, the response of medial prefrontal cortex (mpfc) fs interneurons to the selective 5-ht(1a) receptor agonist 8-oh-dpat and change in expression of 5-ht(1a) receptor on pv-positive neurons were examined in rats with 6-hydroxydopamine (6-ohda) lesions of the substantia nigra pars compacta (snc) by using extracellular recording and double-labeling immunofluorescence histochemistry. |
2012-01-12 |
2023-08-12 |
rat |
| Robert R Rozeske, Andrew K Evans, Matthew G Frank, Linda R Watkins, Christopher A Lowry, Steven F Maie. Uncontrollable, but not controllable, stress desensitizes 5-HT1A receptors in the dorsal raphe nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 40. 2011-11-18. PMID:21976495. |
furthermore, temporary inactivation of the medial prefrontal cortex with the gaba(a) receptor agonist muscimol, which eliminates the protective effects of control on behavior, led even controllable stress to now produce functional desensitization of drn 5-ht(1a) receptors. |
2011-11-18 |
2023-08-12 |
rat |