| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T H Pham, I Mendez-David, C Defaix, B P Guiard, L Tritschler, D J David, A M Gardie. Ketamine treatment involves medial prefrontal cortex serotonin to induce a rapid antidepressant-like activity in BALB/cJ mice. Neuropharmacology. vol 112. issue Pt A. 2017-07-11. PMID:27211253. |
ketamine treatment involves medial prefrontal cortex serotonin to induce a rapid antidepressant-like activity in balb/cj mice. |
2017-07-11 |
2023-08-13 |
mouse |
| Maurizio S Riga, Connie Sánchez, Pau Celada, Francesc Artiga. Involvement of 5-HT3 receptors in the action of vortioxetine in rat brain: Focus on glutamatergic and GABAergic neurotransmission. Neuropharmacology. vol 108. 2017-07-07. PMID:27106166. |
here we assessed vortioxetine effect on pyramidal neuron activity and extracellular 5-ht concentration using in vivo extracellular recordings of rat medial prefrontal cortex (mpfc) pyramidal neurons and microdialysis in mpfc and ventral hippocampus (vhpc). |
2017-07-07 |
2023-08-13 |
rat |
| Ling Na Han, Li Zhang, Yi Na Sun, Cheng Xue Du, Yu Ming Zhang, Tao Wang, Jin Zhang, Jian Li. Serotonin7 receptors in the lateral habenular nucleus regulate depressive-like behaviors in the hemiparkinsonian rats. Brain research. vol 1644. 2017-06-29. PMID:27178363. |
neurochemical results showed that intra-lhb injection of as19 (4μg/rat) decreased dopamine and 5-ht levels in the medial prefrontal cortex, habenula and hippocampus in sham-operated and the lesioned rats; whereas sb269970 (6μg/rat) increased dopamine and 5-ht levels in these structures. |
2017-06-29 |
2023-08-13 |
rat |
| E Fiori, L Babicola, D Andolina, A Coassin, T Pascucci, L Patella, Y-C Han, A Ventura, R Ventur. Neurobehavioral Alterations in a Genetic Murine Model of Feingold Syndrome 2. Behavior genetics. vol 45. issue 5. 2016-12-13. PMID:26026879. |
moreover, dopamine, norepinephrine and serotonin tissue levels in the medial prefrontal cortex (mpfc), and hippocampus (hip) of mir-17-92∆/+ mice were analyzed.our data showed decreased body growth and reduced vocalization during development. |
2016-12-13 |
2023-08-13 |
mouse |
| Inbar Zohar, Shai Shoham, Marta Weinstoc. Perinatal citalopram does not prevent the effect of prenatal stress on anxiety, depressive-like behaviour and serotonergic transmission in adult rat offspring. The European journal of neuroscience. vol 43. issue 4. 2016-12-13. PMID:26669896. |
the current study investigated whether administration of citalopram to pregnant rats could prevent anxiety and depressive-like behaviour induced by gestational stress in their offspring, and restore the expression of serotonin 1a autoreceptors in gabaergic interneurons in the medial prefrontal cortex and dorsal raphe nuclei in males, and of corticotropin-releasing factor type 2 receptors in gabaergic interneurons in the dorsal raphe nuclei in females. |
2016-12-13 |
2023-08-13 |
rat |
| Kenichi Fukumoto, Michihiko Iijima, Shigeyuki Chak. The Antidepressant Effects of an mGlu2/3 Receptor Antagonist and Ketamine Require AMPA Receptor Stimulation in the mPFC and Subsequent Activation of the 5-HT Neurons in the DRN. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 4. 2016-11-08. PMID:26245499. |
given that the projections from the medial prefrontal cortex (mpfc) to the dorsal raphe nucleus (drn), where the majority of serotonin (5-ht) neurons exist, are reportedly involved in the antidepressant effects, in this study, we investigated using the forced swimming test (fst) of c57bl/6j male mice, the role of 5-ht neurons in the drn regulated by the mpfc-drn projections in the antidepressant effects of an mglu2/3 receptor antagonist, ly341495, and ketamine. |
2016-11-08 |
2023-08-13 |
mouse |
| Lara S Hwa, Akiko Shimamoto, Tala Kayyali, Kevin J Norman, Rita J Valentino, Joseph F DeBold, Klaus A Micze. Dissociation of μ-opioid receptor and CRF-R1 antagonist effects on escalated ethanol consumption and mPFC serotonin in C57BL/6J mice. Addiction biology. vol 21. issue 1. 2016-11-01. PMID:25262980. |
extracellular serotonin was measured in the medial prefrontal cortex (mpfc) using in vivo microdialysis after intra-drn microinjections in another group of mice. |
2016-11-01 |
2023-08-13 |
mouse |
| Hamid Moha ou Maati, Céline Bourcier-Lucas, Julie Veyssiere, Ameni Kanzari, Catherine Heurteaux, Marc Borsotto, Nasser Haddjeri, Guillaume Luca. The peptidic antidepressant spadin interacts with prefrontal 5-HT(4) and mGluR(2) receptors in the control of serotonergic function. Brain structure & function. vol 221. issue 1. 2016-10-14. PMID:25233810. |
this study investigates the mechanism of action of spadin, a putative fast-acting peptidic antidepressant (ad) and a functional blocker of the k(+) trek-1 channel, in relation with the medial prefrontal cortex (mpfc)-dorsal raphé (drn) serotonergic (5-ht) neurons connectivity. |
2016-10-14 |
2023-08-13 |
Not clear |
| Christina M Ragan, Kaitlyn M Harding, Joseph S Lonstei. Associations among within-litter differences in early mothering received and later emotional behaviors, mothering, and cortical tryptophan hydroxylase-2 expression in female laboratory rats. Hormones and behavior. vol 77. 2016-09-15. PMID:26219576. |
medial prefrontal cortex expression of tryptophan hydroxylase-2 (tph2; enzyme necessary for serotonin synthesis) was negatively associated with early maternal licking received. |
2016-09-15 |
2023-08-13 |
rat |
| Ling-Ling Fan, Bo Deng, Jun-Bao Yan, Zhi-Hong Hu, Ai-Hong Ren, Yong-Mei Hu, Dong-Wei Yan. [Effect of 5-HT7 receptor agonist on pyramidal neurons in the medial frontal cortex in a rat model of Parkinson's disease]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 36. issue 6. 2016-09-15. PMID:27320874. |
to investigate the activity of pyramidal neurons in the medial prefrontal cortex (mpfc) of normal and 6-ohda-lesioned rats and the responses of the neurons to 5-hydroxytryptamine-7 (5-ht(7)) receptor stimulation. |
2016-09-15 |
2023-08-13 |
rat |
| Mostafa El Mansari, Agnes Crnic, Chris Oosterhof, Pierre Blie. Long-term administration of the antidepressant vilazodone modulates rat brain monoaminergic systems. Neuropharmacology. vol 99. 2016-08-30. PMID:26362359. |
a previous in vivo microdialysis experiment showed that a single administration of vilazodone, dose-dependently increases extracellular 5-ht but not norepinephrine (ne) or dopamine (da) levels in rat medial prefrontal cortex and ventral hippocampus. |
2016-08-30 |
2023-08-13 |
human |
| Mahesh Darna, Jonathan J Chow, Justin R Yates, Richard J Charnigo, Joshua S Beckmann, Michael T Bardo, Linda P Dwoski. Role of serotonin transporter function in rat orbitofrontal cortex in impulsive choice. Behavioural brain research. vol 293. 2016-06-02. PMID:26183652. |
following behavioral evaluation, km and vmax were obtained from kinetic analysis of [(3)h]5-ht uptake by sert using synaptosomes prepared from both orbitofrontal cortex (ofc) and medial prefrontal cortex (mpfc) obtained from each individual rat. |
2016-06-02 |
2023-08-13 |
rat |
| Ravit Hadar, M Luisa Soto-Montenegro, Thomas Götz, Franziska Wieske, Reinhard Sohr, Manuel Desco, Clement Hamani, Ina Weiner, Javier Pascau, Christine Winte. Using a maternal immune stimulation model of schizophrenia to study behavioral and neurobiological alterations over the developmental course. Schizophrenia research. vol 166. issue 1-3. 2016-05-02. PMID:26055633. |
using post mortem hplc we found that mis-rats show distinct dopamine and serotonin changes in the medial prefrontal cortex (mpfc), nucleus accumbens (nacc), caudate putamen, globus pallidus, and hippocampus. |
2016-05-02 |
2023-08-13 |
rat |
| Ken-Ichi Kasahara, Shinji Hashimoto, Tsuyoshi Hattori, Koh Kawasaki, Ryuichi Tsujita, Osamu Nakazono, Katsuyuki Takao, Hiromu Kawakubo, Tadashi Nagatan. The effects of AP521, a novel anxiolytic drug, in three anxiety models and on serotonergic neural transmission in rats. Journal of pharmacological sciences. vol 127. issue 1. 2016-04-25. PMID:25704026. |
tandospirone, which can stimulate the presynaptic 5-ht1a receptors in the raphe, tended to decrease extracellular 5-ht concentration in the medial prefrontal cortex (mpfc) in rats. |
2016-04-25 |
2023-08-13 |
human |
| Noelle C Anastasio, Sonja J Stutz, Latham H L Fink, Sarah E Swinford-Jackson, Robert M Sears, Ralph J DiLeone, Kenner C Rice, F Gerard Moeller, Kathryn A Cunningha. Serotonin (5-HT) 5-HT2A Receptor (5-HT2AR):5-HT2CR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity. ACS chemical neuroscience. vol 6. issue 7. 2016-04-19. PMID:26120876. |
serotonin (5-ht) 5-ht2a receptor (5-ht2ar):5-ht2cr imbalance in medial prefrontal cortex associates with motor impulsivity. |
2016-04-19 |
2023-08-13 |
rat |
| Noelle C Anastasio, Sonja J Stutz, Latham H L Fink, Sarah E Swinford-Jackson, Robert M Sears, Ralph J DiLeone, Kenner C Rice, F Gerard Moeller, Kathryn A Cunningha. Serotonin (5-HT) 5-HT2A Receptor (5-HT2AR):5-HT2CR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity. ACS chemical neuroscience. vol 6. issue 7. 2016-04-19. PMID:26120876. |
recent studies have implicated serotonin (5-ht) systems in medial prefrontal cortex (mpfc) in mediating individual differences in motor impulsivity, notably the 5-ht2ar receptor (5-ht2ar) and 5-ht2cr. |
2016-04-19 |
2023-08-13 |
rat |
| Justin R Yates, Mahesh Darna, Cassandra D Gipson, Linda P Dwoskin, Michael T Bard. Dissociable roles of dopamine and serotonin transporter function in a rat model of negative urgency. Behavioural brain research. vol 291. 2016-03-28. PMID:26005123. |
upon completion of behavioral training, vmax and km were obtained from kinetic analysis of [(3)h]da and [(3)h]5-ht uptake using synaptosomes prepared from nucleus accumbens (nac), dorsal striatum (str), medial prefrontal cortex (mpfc), and orbitofrontal cortex (ofc) isolated from individual rats. |
2016-03-28 |
2023-08-13 |
rat |
| Latham H L Fink, Noelle C Anastasio, Robert G Fox, Kenner C Rice, F Gerard Moeller, Kathryn A Cunningha. Individual Differences in Impulsive Action Reflect Variation in the Cortical Serotonin 5-HT2A Receptor System. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 8. 2016-03-08. PMID:25666313. |
serotonin (5-ht) actions at the 5-ht2ar receptor (5-ht2ar) promote and 5-ht2ar antagonists suppress impulsive action (the inability to withhold premature responses; motor impulsivity) upon systemic administration or microinfusion directly into the medial prefrontal cortex (mpfc), a node in the corticostriatal circuit that is thought to play a role in the regulation of impulsive action. |
2016-03-08 |
2023-08-13 |
rat |
| Francis R Bambico, Baptiste Lacoste, Patrick R Hattan, Gabriella Gobb. Father absence in the monogamous california mouse impairs social behavior and modifies dopamine and glutamate synapses in the medial prefrontal cortex. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 5. 2016-01-19. PMID:24304503. |
here, we examined the behavioral consequences of pd in the california mouse, a species displaying monogamous bonding and biparental care, and assessed its impact on dopamine (da), serotonin (5-ht), and glutamate (glu) transmission in the medial prefrontal cortex (mpfc). |
2016-01-19 |
2023-08-12 |
mouse |
| Juan F Morici, Lucia Ciccia, Gaël Malleret, Jay A Gingrich, Pedro Bekinschtein, Noelia V Weisstau. Serotonin 2a Receptor and Serotonin 1a Receptor Interact Within the Medial Prefrontal Cortex During Recognition Memory in Mice. Frontiers in pharmacology. vol 6. 2016-01-18. PMID:26779016. |
serotonin 2a receptor and serotonin 1a receptor interact within the medial prefrontal cortex during recognition memory in mice. |
2016-01-18 |
2023-08-13 |
mouse |