| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew W Hale, Jodi L Lukkes, Kathleen F Dady, Kyle J Kelly, Evan D Paul, David G Smith, Jared D Heinze, Charles L Raison, Christopher A Lowr. Interactions between whole-body heating and citalopram on body temperature, antidepressant-like behaviour, and neurochemistry in adolescent male rats. Behavioural brain research. vol 359. 2019-04-23. PMID:30468787. |
whole-body heating, by itself, decreased serotonin concentrations in the infralimbic cortex to a level similar to that observed following treatment with citalopram, suggesting that these treatments have convergent effects on a mesolimbocortical system innervating the medial prefrontal cortex, an effect that was correlated with effects of treatment on body temperature. |
2019-04-23 |
2023-08-13 |
rat |
| Yong-Ku Kim, Meysam Amidfar, Eunsoo Wo. A review on inflammatory cytokine-induced alterations of the brain as potential neural biomarkers in post-traumatic stress disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 91. 2019-04-15. PMID:29932946. |
such heightened activity of the immune system may cause alterations in the structure and function of brain regions-for example, the amygdala, hippocampus, medial prefrontal cortex, anterior cingulate cortex, and insula-through changes in levels of serotonin and kynurenine pathway metabolites, and direct neurotoxic effects of cytokines. |
2019-04-15 |
2023-08-13 |
Not clear |
| Jan Kehr, Takashi Yoshitake, Fumio Ichinose, Shimako Yoshitake, Béla Kiss, István Gyertyán, Nika Adha. Effects of cariprazine on extracellular levels of glutamate, GABA, dopamine, noradrenaline and serotonin in the medial prefrontal cortex in the rat phencyclidine model of schizophrenia studied by microdialysis and simultaneous recordings of locomotor activity. Psychopharmacology. vol 235. issue 5. 2019-02-20. PMID:29637288. |
effects of cariprazine on extracellular levels of glutamate, gaba, dopamine, noradrenaline and serotonin in the medial prefrontal cortex in the rat phencyclidine model of schizophrenia studied by microdialysis and simultaneous recordings of locomotor activity. |
2019-02-20 |
2023-08-13 |
rat |
| Diego Andolina, Matteo Di Segni, Alessandra Accoto, Luisa Lo Iacono, Antonella Borreca, Donald Ielpo, Nicola Berretta, Emerald Perlas, Stefano Puglisi-Allegra, Rossella Ventur. MicroRNA-34 Contributes to the Stress-related Behavior and Affects 5-HT Prefrontal/GABA Amygdalar System through Regulation of Corticotropin-releasing Factor Receptor 1. Molecular neurobiology. vol 55. issue 9. 2019-02-04. PMID:29417477. |
we have recently demonstrated that mice carrying a genetic deletion of all mir-34 isoforms (triple knockout, tko) lack the stress-induced serotonin (5-ht) and gaba release in the medial prefrontal cortex (mpfc) and basolateral amygdala (bla), respectively. |
2019-02-04 |
2023-08-13 |
mouse |
| Mary C Elliott, Peter M Tanaka, Ryan W Schwark, Rodrigo Andrad. Serotonin Differentially Regulates L5 Pyramidal Cell Classes of the Medial Prefrontal Cortex in Rats and Mice. eNeuro. vol 5. issue 1. 2019-01-02. PMID:29445767. |
serotonin differentially regulates l5 pyramidal cell classes of the medial prefrontal cortex in rats and mice. |
2019-01-02 |
2023-08-13 |
mouse |
| Marta Gordillo-Salas, Fuencisla Pilar-Cuéllar, Yves P Auberson, Albert Adel. Signaling pathways responsible for the rapid antidepressant-like effects of a GluN2A-preferring NMDA receptor antagonist. Translational psychiatry. vol 8. issue 1. 2018-12-11. PMID:29666360. |
in a previous study we found that the preferring glun2a receptor antagonist, nvp-aam077, elicited rapid antidepressant-like effects in the forced swim test that was related to the release of glutamate and serotonin in the medial prefrontal cortex. |
2018-12-11 |
2023-08-13 |
Not clear |
| Raúl López-Arnau, Mario Buenrostro-Jáuregui, Jorge Camarasa, David Pubill, Elena Escubed. Effect of the combination of mephedrone plus ethanol on serotonin and dopamine release in the nucleus accumbens and medial prefrontal cortex of awake rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 391. issue 3. 2018-11-26. PMID:29349706. |
effect of the combination of mephedrone plus ethanol on serotonin and dopamine release in the nucleus accumbens and medial prefrontal cortex of awake rats. |
2018-11-26 |
2023-08-13 |
rat |
| Juraj Culman, Stephan Mühlenhoff, Annegret Blume, Jürgen Hedderich, Ulf Lützen, Stephen P Hunt, Nadia M J Rupniak, Yi Zha. The Hypothalamic-Pituitary-Adrenal Axis and Serotonin Metabolism in Individual Brain Nuclei of Mice with Genetic Disruption of the NK1 Receptor Exposed to Acute Stress. Cellular and molecular neurobiology. vol 38. issue 6. 2018-10-25. PMID:29948553. |
in the frontoparietal cortex, medial prefrontal cortex, central nucleus of amygdala, and the hippocampal ca1 region, stress increased 5-ht and/or 5-hydroxyindoleacetic acid (5-hiaa) concentrations to a similar extent in wt and nk1r-/- mice. |
2018-10-25 |
2023-08-13 |
mouse |
| Huijun Zhong, Jie Dang, Zhenghao Huo, Zhanbing Ma, Jing Chen, Yong Huang, Yongsheng Zhu, Min L. Effects of medial prefrontal cortex 5-HT Brain research. vol 1678. 2018-07-16. PMID:29155092. |
effects of medial prefrontal cortex 5-ht heroin abuse is linked to a deleterious effect on cognitive functioning in the individual. |
2018-07-16 |
2023-08-13 |
Not clear |
| Victor Mathis, Lucas Lecourtie. Role of the lateral habenula in memory through online processing of information. Pharmacology, biochemistry, and behavior. vol 162. 2018-06-18. PMID:28709783. |
animal research has recently attracted attention on the lateral habenula which, as shown in rodents and non-human primates, seems to process information stemming in the main regions involved in memory processing, e.g., the medial prefrontal cortex, the hippocampus, the amygdala, the septal region, the basal ganglia, and participates in the control of key memory-related neurotransmitters systems, i.e., dopamine, serotonin, acetylcholine. |
2018-06-18 |
2023-08-13 |
Not clear |
| Alexandra Jean, Laetitia Laurent, Sabira Delaunay, Stéphane Doly, Nicole Dusticier, David Linden, Rachael Neve, Luc Maroteaux, André Nieoullon, Valérie Compa. Adaptive Control of Dorsal Raphe by 5-HT4 in the Prefrontal Cortex Prevents Persistent Hypophagia following Stress. Cell reports. vol 21. issue 4. 2018-06-13. PMID:29069597. |
this network consists of the ascending serotonergic inputs from the dorsal raphe nucleus (dr) to the medial prefrontal cortex (mpfc). specifically, adult restoration of serotonin 4 receptor (5-ht |
2018-06-13 |
2023-08-13 |
Not clear |
| Jeffrey M Witkin, Jennifer Li, Gary Gilmour, Stephen N Mitchell, Guy Carter, Scott D Gleason, Wesley F Seidel, Brian J Eastwood, Andrew McCarthy, Warren J Porter, Jon Reel, Kevin M Gardinier, Akihiko S Kato, Keith A Waffor. Electroencephalographic, cognitive, and neurochemical effects of LY3130481 (CERC-611), a selective antagonist of TARP-γ8-associated AMPA receptors. Neuropharmacology. vol 126. 2018-06-12. PMID:28757050. |
evaluation of the effect of ly3130481 on neurotransmitter and metabolite efflux in the rat medial prefrontal cortex, using in vivo microdialysis, revealed significant increases in the pro-cognitive and wake-promoting neurotransmitters, histamine and acetylcholine, as well as in serotonin, telemethylhistamine, 5-hiaa, hva and mhpg. |
2018-06-12 |
2023-08-13 |
mouse |
| Cindy S Tao, Prateek Dhamija, Linda Booij, Janet L Menar. Adversity in early adolescence promotes an enduring anxious phenotype and increases serotonergic innervation of the infralimbic medial prefrontal cortex. Neuroscience. vol 364. 2018-06-08. PMID:28893650. |
after behavioural testing, we used immunohistochemistry for the 5-ht transporter (sert) to evaluate 5-ht innervation profiles in the medial prefrontal cortex (mpfc) and ventral hippocampus (vh). |
2018-06-08 |
2023-08-13 |
rat |
| Mona El-Sayed Hervig, Nadja Cecilie Hvid Jensen, Nadja Bredo Rasmussen, Rasmus Rydbirk, Mikkel Vestergaard Olesen, Anders Hay-Schmidt, Bente Pakkenberg, Susana Azna. Involvement of serotonin 2A receptor activation in modulating medial prefrontal cortex and amygdala neuronal activation during novelty-exposure. Behavioural brain research. vol 326. 2018-03-07. PMID:28263831. |
involvement of serotonin 2a receptor activation in modulating medial prefrontal cortex and amygdala neuronal activation during novelty-exposure. |
2018-03-07 |
2023-08-13 |
Not clear |
| Luka R Srejic, Kevin M Wood, Anisa Zeqja, Parastoo Hashemi, William D Hutchiso. Modulation of serotonin dynamics in the dorsal raphe nucleus via high frequency medial prefrontal cortex stimulation. Neurobiology of disease. vol 94. 2018-02-27. PMID:27326670. |
modulation of serotonin dynamics in the dorsal raphe nucleus via high frequency medial prefrontal cortex stimulation. |
2018-02-27 |
2023-08-13 |
mouse |
| Iku Tsutsui-Kimura, Yu Ohmura, Takayuki Yoshida, Mitsuhiro Yoshiok. Milnacipran affects mouse impulsive, aggressive, and depressive-like behaviors in a distinct dose-dependent manner. Journal of pharmacological sciences. vol 134. issue 3. 2018-01-03. PMID:28694090. |
a milnacipran dose of 10 mg/kg suppressed all behaviors, which was accompanied by increased dopamine and serotonin levels in the medial prefrontal cortex (mpfc) but not in the nucleus accumbens (nac). |
2018-01-03 |
2023-08-13 |
mouse |
| Celia Kjaerby, Jegath Athilingam, Sarah E Robinson, Jillian Iafrati, Vikaas S Soha. Serotonin 1B Receptors Regulate Prefrontal Function by Gating Callosal and Hippocampal Inputs. Cell reports. vol 17. issue 11. 2017-11-28. PMID:27974203. |
both medial prefrontal cortex (mpfc) and serotonin play key roles in anxiety; however, specific mechanisms through which serotonin might act on the mpfc to modulate anxiety-related behavior remain unknown. |
2017-11-28 |
2023-08-13 |
mouse |
| Sebastian Pablo Fernandez, Bruno Cauli, Carolina Cabezas, Aude Muzerelle, Jean-Christophe Poncer, Patricia Gaspa. Multiscale single-cell analysis reveals unique phenotypes of raphe 5-HT neurons projecting to the forebrain. Brain structure & function. vol 221. issue 8. 2017-10-10. PMID:26608830. |
we compared the electrophysiological and neurochemical properties of dorsal and median raphe 5-ht neurons projecting to the medial prefrontal cortex (mpfc), amygdala (bla) and dorsal hippocampus (dhp), combining retrograde tract tracing with brain slice electrophysiology and single-cell rt-pcr in pet1-egfp mice. |
2017-10-10 |
2023-08-13 |
mouse |
| Hao-Qiang Zhang, Yong Zhang, Lin Liu, Jin-Lian Li, Ya-Cheng Lu, Ying-Ying Yu, Hui Li, Ting Zhang, Ying-Shing Chan, Fu-Xing Zhang, Yun-Qing L. Neural connection supporting endogenous 5-hydroxytryptamine influence on autonomic activity in medial prefrontal cortex. Autonomic neuroscience : basic & clinical. vol 203. 2017-08-21. PMID:27932203. |
neural connection supporting endogenous 5-hydroxytryptamine influence on autonomic activity in medial prefrontal cortex. |
2017-08-21 |
2023-08-13 |
Not clear |
| Hao-Qiang Zhang, Yong Zhang, Lin Liu, Jin-Lian Li, Ya-Cheng Lu, Ying-Ying Yu, Hui Li, Ting Zhang, Ying-Shing Chan, Fu-Xing Zhang, Yun-Qing L. Neural connection supporting endogenous 5-hydroxytryptamine influence on autonomic activity in medial prefrontal cortex. Autonomic neuroscience : basic & clinical. vol 203. 2017-08-21. PMID:27932203. |
5-hydroxytryptamine (5-ht) transmission in the medial prefrontal cortex (mpfc) enhances or suppresses signal outflow to influence emotion-/cognition-based function performances and, putatively, the autonomic responses. |
2017-08-21 |
2023-08-13 |
Not clear |