| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lakshmi Rajagopal, Mei Huang, Wenqi He, Chelsea Ryan, Ahmad Elzokaky, Pradeep Banerjee, Herbert Y Meltze. Repeated administration of rapastinel produces exceptionally prolonged rescue of memory deficits in phencyclidine-treated mice. Behavioural brain research. 2022-06-19. PMID:35718230. |
both rapastinel (3mg/kg) and ketamine (30mg/kg), moderately increased the efflux of dopamine, norepinephrine, and serotonin in medial prefrontal cortex; however, only ketamine increased cortical glutamate efflux. |
2022-06-19 |
2023-08-14 |
mouse |
| Yassine Ait Bali, Nour-Eddine Kaikai, Saadia Ba-M'hamed, Marco Sassoè-Pognetto, Maurizio Giustetto, Mohamed Benni. Anxiety and Gene Expression Enhancement in Mice Exposed to Glyphosate-Based Herbicide. Toxics. vol 10. issue 5. 2022-05-27. PMID:35622640. |
growing evidence demonstrates that serotonin (5-ht) depletion increases activity in the amygdala and medial prefrontal cortex (mpfc), ultimately leading to anxiety behavior. |
2022-05-27 |
2023-08-13 |
mouse |
| Zijian Lv, Yuting Zhang, Lizi Zhang, Wenjuan Hou, Miao Lin, Yufeng Xun, Huan Ma, Yin Li, Yitong Li, Fadao Tai, Zhixiong H. Involvement of DR→mPFC 5-HTergic neural projections in changes of social exploration behaviors caused by adult chronic social isolation in mice. Brain research bulletin. 2022-05-08. PMID:35526586. |
this study assessed whether five weeks of continuous si at adulthood could alter social behaviors and whether dorsal raphe nucleus (dr) to medial prefrontal cortex (mpfc) 5-ht neural projections were involved in this alteration in c57bl/6j adult male mice. |
2022-05-08 |
2023-08-13 |
mouse |
| Ye Wang, Yunyun Zhang, Kai Wang, Zhenghua Zhu, Dan Wang, Qianzi Yang, Hailong Don. Esketamine Increases Neurotransmitter Releases but Simplifies Neurotransmitter Networks in Mouse Prefrontal Cortex. Journal of neurophysiology. 2022-01-26. PMID:35080449. |
the esketamine-increased gamma oscillation power was positively correlated only with the concentration of 5-hydroxytryptamine (5-ht) in the medial prefrontal cortex. |
2022-01-26 |
2023-08-13 |
mouse |
| Brett A Hathaway, Jackson D Schumacher, Kelly M Hrelja, Catharine A Winstanle. Serotonin 2C Antagonism in the Lateral Orbitofrontal Cortex Ameliorates Cue-Enhanced Risk Preference and Restores Sensitivity to Reinforcer Devaluation in Male Rats. eNeuro. vol 8. issue 6. 2021-12-11. PMID:34815296. |
we therefore assessed whether the serotonin 2c receptor antagonist rs 102221 is able to attenuate cue-enhanced risk preference via its actions in the lateral orbitofrontal cortex (lofc) or prelimbic (prl) area of the medial prefrontal cortex (mpfc). |
2021-12-11 |
2023-08-13 |
human |
| R B Malvestio, P Medeiros, S E Negrini-Ferrari, M Oliveira-Silva, A C Medeiros, C M Padovan, L Luongo, S Maione, N C Coimbra, R L de Freita. Cannabidiol in the prelimbic cortex modulates the comorbid condition between the chronic neuropathic pain and depression-like behaviour in rats: The role of medial prefrontal cortex 5-HT Brain research bulletin. vol 174. 2021-12-10. PMID:34192579. |
cannabidiol in the prelimbic cortex modulates the comorbid condition between the chronic neuropathic pain and depression-like behaviour in rats: the role of medial prefrontal cortex 5-ht the prelimbic division (prl) of the medial prefrontal cortex (mpfc) is a cerebral division that is putatively implicated in the chronic pain and depression. |
2021-12-10 |
2023-08-13 |
rat |
| Guanlong Guo, Jiaxin Tang, Mengwen Shi, Chengmei Yang, Huaxing Ou, Weihai Che. MK212, a 5-hydroxytryptamine 2C receptor agonist, reverses prepulse inhibition deficits in the medial prefrontal cortex and ventral hippocampus. Progress in neuro-psychopharmacology & biological psychiatry. vol 113. 2021-12-06. PMID:34560172. |
mk212, a 5-hydroxytryptamine 2c receptor agonist, reverses prepulse inhibition deficits in the medial prefrontal cortex and ventral hippocampus. |
2021-12-06 |
2023-08-13 |
Not clear |
| Xiao Liu, Ya-Xin Sun, Chen-Chen Zhang, Xian-Qiang Zhang, Yue Zhang, Ting Wang, Yu-Nu Ma, Han Wang, Yun-Ai Su, Ji-Tao Li, Tian-Mei S. Vortioxetine attenuates the effects of early-life stress on depression-like behaviors and monoamine transporters in female mice. Neuropharmacology. vol 186. 2021-11-05. PMID:33485943. |
moreover, systemic 21-day treatment with vortioxetine, a novel multimodal antidepressant, successfully reversed depression-like behaviors and normalized some molecular changes, including that of the norepinephrine transporter in the medial prefrontal cortex, vesicular monoamine transporter 2 in nucleus accumbens core, and serotonin transporter in amygdala. |
2021-11-05 |
2023-08-13 |
mouse |
| A Ezequiel Pereyra, Camilo J Mininni, B Silvano Zanutt. Information capacity and robustness of encoding in the medial prefrontal cortex are modulated by the bioavailability of serotonin and the time elapsed from the cue during a reward-driven task. Scientific reports. vol 11. issue 1. 2021-11-04. PMID:34230550. |
information capacity and robustness of encoding in the medial prefrontal cortex are modulated by the bioavailability of serotonin and the time elapsed from the cue during a reward-driven task. |
2021-11-04 |
2023-08-13 |
rat |
| A Ezequiel Pereyra, Camilo J Mininni, B Silvano Zanutt. Information capacity and robustness of encoding in the medial prefrontal cortex are modulated by the bioavailability of serotonin and the time elapsed from the cue during a reward-driven task. Scientific reports. vol 11. issue 1. 2021-11-04. PMID:34230550. |
serotonin (5-ht) is a key neuromodulator of medial prefrontal cortex (mpfc) functions. |
2021-11-04 |
2023-08-13 |
rat |
| Chen Li, Fantao Meng, Jacob C Garza, Jing Liu, Yun Lei, Sergei A Kirov, Ming Guo, Xin-Yun L. Modulation of depression-related behaviors by adiponectin AdipoR1 receptors in 5-HT neurons. Molecular psychiatry. vol 26. issue 8. 2021-11-02. PMID:31980728. |
the expression levels of tph2 were downregulated with a concurrent reduction of 5-ht-immunoreactivity in the drn and its two major projection regions, the hippocampus and medial prefrontal cortex (mpfc), in male but not female mice lacking adipor1 in 5-ht neurons. |
2021-11-02 |
2023-08-13 |
mouse |
| Tudor M Ionescu, Mario Amend, Rakibul Hafiz, Bharat B Biswal, Andreas Maurer, Bernd J Pichler, Hans F Wehrl, Kristina Herfer. Striatal and prefrontal D2R and SERT distributions contrastingly correlate with default-mode connectivity. NeuroImage. vol 243. 2021-10-29. PMID:34428573. |
the aim of this study was elucidating interactions between dopamine d2 receptors (d2r) and serotonin transporter (sert) availabilities in the striatum (cpu) and medial prefrontal cortex (mpfc), two of the main dopaminergic and serotonergic projection areas, and the default-mode network. |
2021-10-29 |
2023-08-13 |
rat |
| Matteo Marti, Giuseppe Talani, Cristina Miliano, Sabrine Bilel, Francesca Biggio, Jessica Bratzu, Marco Diana, Maria Antonietta De Luca, Liana Fattor. New insights into methoxetamine mechanisms of action: Focus on serotonergic 5-HT Experimental neurology. vol 345. 2021-09-07. PMID:34384790. |
is able to significantly alter serotonin levels in the rat medial prefrontal cortex (mpfc) and nucleus accumbens. |
2021-09-07 |
2023-08-13 |
mouse |
| Johan Alsiö, Olivia Lehmann, Colin McKenzie, David E Theobald, Lydia Searle, Jing Xia, Jeffrey W Dalley, Trevor W Robbin. Serotonergic Innervations of the Orbitofrontal and Medial-prefrontal Cortices are Differentially Involved in Visual Discrimination and Reversal Learning in Rats. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 2. 2021-08-11. PMID:33043981. |
the aim of the current study was to investigate the contribution of serotonin within the orbitofrontal cortex (ofc) and medial prefrontal cortex (mpfc) to visual discrimination and reversal learning. |
2021-08-11 |
2023-08-13 |
rat |
| Katsumasa Muneoka, Yasunori Oda, Masaaki Iwata, Masaomi Iyo, Kenji Hashimoto, Yukihiko Shirayam. Monoaminergic balances predict non-depression-like phenotype in Learned Helplessness Paradigm. Neuroscience. vol 440. 2021-05-14. PMID:32222554. |
here, we measured the levels of monoamines, including noradrenaline (na), serotonin (5-ht), and dopamine (da), and their metabolites in the medial prefrontal cortex (mpfc), orbitofrontal cortex (ofc), hippocampus, nucleus accumbens (nac), amygdala, and striatum in lh, non-lh, and non-manipulated (naïve) rats. |
2021-05-14 |
2023-08-13 |
rat |
| Ana Margarida Cunha, Marco Rafael Guimarães, Nikolaos Kokras, Ioannis Sotiropoulos, Nuno Sousa, Armando Almeida, Christina Dalla, Hugo Leite-Almeid. Mesocorticolimbic monoamines in a rodent model of chronic neuropathic pain. Neuroscience letters. vol 737. 2021-04-30. PMID:32818589. |
in this study, we analyzed the levels of monoamines dopamine (da), noradrenaline (na) and serotonin (5-ht) in mesocorticolimbic areas - medial prefrontal cortex, orbitofrontal cortex, striatum, nucleus accumbens and amygdala - 1 month after a neuropathic lesion, spared nerve injury (sni). |
2021-04-30 |
2023-08-13 |
Not clear |
| Jinling Chu, Satoshi Deyama, Xueting Li, Mei Motono, Atsuki Otoda, Atsushi Saito, Hirohito Esaki, Naoya Nishitani, Katsuyuki Kaned. Role of 5-HT Neuroscience letters. vol 743. 2021-04-29. PMID:33352288. |
this study aimed to examine the role of serotonergic transmission in the medial prefrontal cortex (mpfc) in cocaine cpp enhancement by acute restraint stress, which increases extracellular serotonin (5-ht) levels in the mpfc. |
2021-04-29 |
2023-08-13 |
mouse |
| Karl-Jürgen Bär, Stefanie Köhler, Feliberto de la Cruz, Andy Schumann, Florian D Zepf, Gerd Wagne. Functional consequences of acute tryptophan depletion on raphe nuclei connectivity and network organization in healthy women. NeuroImage. vol 207. 2021-03-03. PMID:31743788. |
the underlying neural networks comprise core subcortical/cortical regions such as amygdala and medial prefrontal cortex, which are assumed to be modulated amongst others by 5-ht. |
2021-03-03 |
2023-08-13 |
human |
| Katsuhiko Miyazaki, Kayoko W Miyazaki, Gaston Sivori, Akihiro Yamanaka, Kenji F Tanaka, Kenji Doy. Serotonergic projections to the orbitofrontal and medial prefrontal cortices differentially modulate waiting for future rewards. Science advances. vol 6. issue 48. 2020-12-07. PMID:33246957. |
we also found that serotonin stimulation in the medial prefrontal cortex (mpfc) promotes waiting only when the timing of future rewards is uncertain. |
2020-12-07 |
2023-08-13 |
Not clear |
| Sarah B Winokur, Keianna L Lopes, Yashaswani Moparthi, Mariana Pereir. Depression-related disturbances in rat maternal behaviour are associated with altered monoamine levels within mesocorticolimbic structures. Journal of neuroendocrinology. vol 31. issue 9. 2020-10-13. PMID:31265182. |
levels of the monoamine neurotransmitters, dopamine, noradrenaline and serotonin, as well as their major metabolites, were measured within the medial prefrontal cortex, striatum, nucleus accumbens and medial preoptic area of sd and wky mothers at early (postpartum day [ppd]7-8), late (ppd15-16) and weaning (ppd25) postpartum stages using high-performance liquid chromatography with electrochemical detection. |
2020-10-13 |
2023-08-13 |
rat |