| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gerdien A H Korte-Bouws, Floor van Heesch, Koen G C Westphal, Lisa M J Ankersmit, Edwin M van Oosten, Onur Güntürkün, S Mechiel Kort. Bacterial Lipopolysaccharide Increases Serotonin Metabolism in Both Medial Prefrontal Cortex and Nucleus Accumbens in Male Wild Type Rats, but Not in Serotonin Transporter Knockout Rats. Pharmaceuticals (Basel, Switzerland). vol 11. issue 3. 2020-10-01. PMID:29976854. |
bacterial lipopolysaccharide increases serotonin metabolism in both medial prefrontal cortex and nucleus accumbens in male wild type rats, but not in serotonin transporter knockout rats. |
2020-10-01 |
2023-08-13 |
rat |
| Gerdien A H Korte-Bouws, Floor van Heesch, Koen G C Westphal, Lisa M J Ankersmit, Edwin M van Oosten, Onur Güntürkün, S Mechiel Kort. Bacterial Lipopolysaccharide Increases Serotonin Metabolism in Both Medial Prefrontal Cortex and Nucleus Accumbens in Male Wild Type Rats, but Not in Serotonin Transporter Knockout Rats. Pharmaceuticals (Basel, Switzerland). vol 11. issue 3. 2020-10-01. PMID:29976854. |
administered lps increased extracellular monoamine metabolite levels in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc), which was completely, or at least partly, prevented by pretreatment with a triple reuptake inhibitor that also blocks the serotonin (5-ht) transporter (sert). |
2020-10-01 |
2023-08-13 |
rat |
| David J Mokler, Jill A McGaughy, Donna Bass, Peter J Morgane, Douglas L Rosene, Ana C Amaral, R Jarrett Rushmore, Janina R Galle. Prenatal Protein Malnutrition Leads to Hemispheric Differences in the Extracellular Concentrations of Norepinephrine, Dopamine and Serotonin in the Medial Prefrontal Cortex of Adult Rats. Frontiers in neuroscience. vol 13. 2020-10-01. PMID:30890908. |
prenatal protein malnutrition leads to hemispheric differences in the extracellular concentrations of norepinephrine, dopamine and serotonin in the medial prefrontal cortex of adult rats. |
2020-10-01 |
2023-08-13 |
rat |
| Iva Lukić, Dmitriy Getselter, Omry Koren, Evan Elliot. Role of Tryptophan in Microbiota-Induced Depressive-Like Behavior: Evidence From Tryptophan Depletion Study. Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:31231198. |
in addition, in mice that were not subjected to atd, gf mice displayed higher levels of tryptophan, serotonin and 5-hydroxyindoleacetic acid (the main degradation product of serotonin) in medial prefrontal cortex (mpfc) and hippocampus (hippo), compared to spf mice. |
2020-10-01 |
2023-08-13 |
mouse |
| Motohiro Okada, Kouji Fukuyama, Ruri Okubo, Takashi Shiroyama, Yuto Ued. Lurasidone Sub-Chronically Activates Serotonergic Transmission via Desensitization of 5-HT1A and 5-HT7 Receptors in Dorsal Raphe Nucleus. Pharmaceuticals (Basel, Switzerland). vol 12. issue 4. 2020-09-30. PMID:31590422. |
following systemic and local administrations of lurasidone, mk801 and 5-ht receptor modulators, we determined releases of 5-ht in dorsal raphe nucleus (drn), mediodorsal thalamic nucleus (mdtn) and medial prefrontal cortex (mpfc) and γ-aminobutyric acid (gaba) in drn using multiprobe microdialysis with ultra-high-performance liquid chromatography (uhplc). |
2020-09-30 |
2023-08-13 |
Not clear |
| Yassine Ait Bali, Saadia Ba-Mhamed, Mohamed Benni. Behavioral and Immunohistochemical Study of the Effects of Subchronic and Chronic Exposure to Glyphosate in Mice. Frontiers in behavioral neuroscience. vol 11. 2020-09-29. PMID:28848410. |
after completion of the behavioral testing, adult mice were sacrificed and the expression of tyrosine hydroxylase (th) in the substantia nigra pars compacta (snc) and serotonin (5-ht) in the dorsal raphe nucleus (drn), the basolateral amygdala (bla) and the ventral medial prefrontal cortex (mpfc) was evaluated using immunohistochemical procedure. |
2020-09-29 |
2023-08-13 |
mouse |
| Bombi Lee, Gwang Muk Choi, Insop Shim, Hyejung Le. Genistein Prevents Single Prolonged Stress-Induced Cognitive Impairment in a Post-Traumatic Stress Disorder Rat Model via Activation of the Serotonergic System. Journal of medicinal food. vol 23. issue 5. 2020-09-22. PMID:32267780. |
gen treatment also inhibited sps-induced decreases in serotonin (5-ht) levels in the medial prefrontal cortex and hippocampus. |
2020-09-22 |
2023-08-13 |
rat |
| Aya Abdalla, Alyssa West, Yunju Jin, Rachel A Saylor, Beidi Qiang, Edsel Peña, David J Linden, H Frederik Nijhout, Michael C Reed, Janet Best, Parastoo Hashem. Fast serotonin voltammetry as a versatile tool for mapping dynamic tissue architecture: I. Responses at carbon fibers describe local tissue physiology. Journal of neurochemistry. vol 153. issue 1. 2020-08-31. PMID:31419307. |
evoked and ambient serotonin in these brain areas, the ca2 region of the hippocampus and the medial prefrontal cortex, are compared to ambient and evoked serotonin in the substantia nigra pars reticulata, an area well established previously for serotonin measurements with fast voltammetry. |
2020-08-31 |
2023-08-13 |
mouse |
| Jin Zhang, Yong Wang, Yi Na Sun, Li Bo Li, Li Zhang, Yuan Guo, Tao Wang, Lu Yao, Li Chen, Jian Li. Blockade of calcium-permeable AMPA receptors in the lateral habenula produces increased antidepressant-like effects in unilateral 6-hydroxydopamine-lesioned rats compared to sham-lesioned rats. Neuropharmacology. vol 157. 2020-07-21. PMID:31251995. |
blockade of lhb cp-ampars decreased the firing rate of the neurons and increased release of dopamine and serotonin in the medial prefrontal cortex (mpfc) in both groups, but the duration of naspm action on the firing rate and release of the transmitters were prolonged in snc-lesioned rats. |
2020-07-21 |
2023-08-13 |
rat |
| Pollyana C Leal, José Marcos M Bispo, Rovena C G J Engelberth, Kayo Diogenes de A Silva, Ywlliane R Meurer, Alessandra M Ribeiro, Regina H Silva, Murilo Marchioro, José R Santo. Serotonergic dysfunction in a model of parkinsonism induced by reserpine. Journal of chemical neuroanatomy. vol 96. 2020-06-15. PMID:30597197. |
after st, 5-ht immunoreactivity decreased in hippocampal subareas (ca1 and ca3) and medial prefrontal cortex (mpfc) compared to vehicle. |
2020-06-15 |
2023-08-13 |
rat |
| Hiromi Tanaka, Ayuka Ehara, Kazuhiko Nakadate, Kanji Yoshimoto, Kazutaka Shimoda, Shuich Ued. Behavioral, hormonal, and neurochemical outcomes of neonatal repeated shaking brain injury in male adult rats. Physiology & behavior. vol 199. 2020-03-20. PMID:30465805. |
furthermore, the neurochemical analysis showed that shaken rats had higher dopamine (da), serotonin (5-ht), 5-hydroxyindolacetic acid (5-hiaa), and noradrenaline (na) levels in the dorsal part of the medial prefrontal cortex (dmpfc). |
2020-03-20 |
2023-08-13 |
rat |
| Deepthi D'Souza, Monika Sadanand. Stressor during Early Adolescence in Hyperreactive Female Wistar Kyoto Rats Induces a 'Double Hit' Manifested by Variation in Neurobehaviors and Brain Monoamines. Neuroscience. vol 414. 2020-03-13. PMID:31279049. |
medial prefrontal cortex, a still maturing brain area, exhibited increased serotonin (5-ht) metabolite (p < 0.01) and turnover rates (p < 0.01) indicative of altered/maladaptive serotonergic functioning. |
2020-03-13 |
2023-08-13 |
rat |
| P C Leal, J M M Bispo, L C R F Lins, M F Souza, A M Gois, C Moore, M Marchioro, A M Ribeiro, R H Silva, C K Meshul, J R Santo. Cognitive and anxiety-like impairments accompanied by serotonergic ultrastructural and immunohistochemical alterations in early stages of parkinsonism. Brain research bulletin. vol 146. 2020-03-10. PMID:30641120. |
besides, tyrosine hydroxylase (th) immunoreactive cells decreased in reserpine (res) group in ca1 and serotonin (5-ht) immunoreactive cells decreased in res group in ca1, ca3 and medial prefrontal cortex (mpfc). |
2020-03-10 |
2023-08-13 |
rat |
| Jin Zhang, Shuxuan Lv, Guoyi Tang, Guanyun Bian, Yaxin Yang, Ruotong Li, Jie Yang, Jian Li. Activation of calcium-impermeable GluR2-containing AMPA receptors in the lateral habenula produces antidepressant-like effects in a rodent model of Parkinson's disease. Experimental neurology. vol 322. 2020-02-24. PMID:31499061. |
we further found that intra-lhb injection of (s)-ampa excited dopaminergic neurons in the anterior ventral tegmental area (avta) and serotonergic neurons in the dorsal raphe nucleus (drn), which increased release of da and 5-ht in the medial prefrontal cortex (mpfc), while nbqx induced the opposite effects. |
2020-02-24 |
2023-08-13 |
rat |
| Karen L Smith, Jacobi I Cunningham, David J Eyerman, Reginald L Dean, Daniel R Deaver, Connie Sanche. Opioid system modulators buprenorphine and samidorphan alter behavior and extracellular neurotransmitter concentrations in the Wistar Kyoto rat. Neuropharmacology. vol 146. 2020-01-23. PMID:30448421. |
sam attenuated bup-induced changes of extracellular levels of serotonin and dopamine in the medial prefrontal cortex and nucleus accumbens shell. |
2020-01-23 |
2023-08-13 |
rat |
| Alyssa West, Janet Best, Aya Abdalla, H Frederik Nijhout, Michael Reed, Parastoo Hashem. Voltammetric evidence for discrete serotonin circuits, linked to specific reuptake domains, in the mouse medial prefrontal cortex. Neurochemistry international. vol 123. 2019-12-26. PMID:30031052. |
voltammetric evidence for discrete serotonin circuits, linked to specific reuptake domains, in the mouse medial prefrontal cortex. |
2019-12-26 |
2023-08-13 |
mouse |
| Yongli Chang, Chengxue Du, Lingna Han, Shuxuan Lv, Jin Zhang, Guanyun Bian, Guoyi Tang, Yiwei Liu, Tao Chen, Jian Li. Enhanced AMPA receptor-mediated excitatory transmission in the rodent rostromedial tegmental nucleus following lesion of the nigrostriatal pathway. Neurochemistry international. vol 122. 2019-12-26. PMID:30448565. |
further, intra-rmtg injection of (s)-ampa decreased the levels of dopamine and serotonin in the medial prefrontal cortex (mpfc) in the two groups of rats; conversely, nbqx increased the levels of dopamine and serotonin. |
2019-12-26 |
2023-08-13 |
rat |
| Haiyan Li, Chihiro Ishikawa, Takashi Shig. Effects of postnatal handling on adult behavior and brain mRNA expression of serotonin receptor, brain-derived neurotrophic factor and GABA-A receptor subunit. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 68. 2019-08-06. PMID:29678562. |
next, to elucidate mechanisms underlying the behavioral effects, we evaluated mrna expression of the serotonin 1a (5-ht1a) receptor, brain-derived neurotrophic factor (bdnf), and gaba-a receptor subunits in the medial prefrontal cortex, amygdala, dorsal and ventral hippocampi, and dorsal raphe nucleus by quantitative rt-pcr, since these genes and brain regions have been shown to be involved in cognition and emotion. |
2019-08-06 |
2023-08-13 |
mouse |
| Lidiane P Garcia, Josefine S Witteveen, Anthonieke Middelman, Josephus A van Hulten, Gerard J M Martens, Judith R Homberg, Sharon M Kol. Perturbed Developmental Serotonin Signaling Affects Prefrontal Catecholaminergic Innervation and Cortical Integrity. Molecular neurobiology. vol 56. issue 2. 2019-07-11. PMID:29948943. |
proper development of the medial prefrontal cortex (mpfc), crucial for correct cognitive functioning, requires projections from, among others, the serotonergic (5-ht) and catecholaminergic systems, but it is unclear how these systems influence each other during development. |
2019-07-11 |
2023-08-13 |
rat |
| Shuo Wang, Yasushi Yabuki, Kazuya Matsuo, Jing Xu, Hisanao Izumi, Kenji Sakimura, Takashi Saito, Takaomi C Saido, Kohji Fukunag. T-type calcium channel enhancer SAK3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice. PloS one. vol 13. issue 12. 2019-04-29. PMID:30571684. |
significantly promoted da and 5-ht releases in the naive mouse hippocampal ca1 region but not in the medial prefrontal cortex (mpfc), while sak3 did not affect na release in either brain region. |
2019-04-29 |
2023-08-13 |
mouse |