| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M P Gallowa. Regulation of dopamine and serotonin synthesis by acute administration of cocaine. Synapse (New York, N.Y.). vol 6. issue 1. 1990-10-18. PMID:2119072. |
procaine (30 mumols/kg) did not inhibit da or 5ht synthesis and prior treatment with reserpine diminished the effectiveness of cocaine in the medial prefrontal cortex, but not in the striatum. |
1990-10-18 |
2023-08-11 |
Not clear |
| W J McBride, J M Murphy, L Lumeng, T K L. Serotonin, dopamine and GABA involvement in alcohol drinking of selectively bred rats. Alcohol (Fayetteville, N.Y.). vol 7. issue 3. 1990-06-05. PMID:2184832. |
neurochemical data indicate that high alcohol-seeking behavior (when compared with data from rats with low alcohol-seeking characteristics) is associated with: a) lower (10-20%; p less than 0.05) contents of 5-ht in certain limbic regions (e.g., nucleus accumbens, frontal cortex, hypothalamus and hippocampus); b) a lower (10-15%; p less than 0.05) content of da in the nucleus accumbens; c) higher (20-35%; p less than 0.05) densities of 5-ht1a binding sites in some limbic regions (e.g., medial nucleus accumbens, medial prefrontal cortex and ventral hippocampus); and d) a greater (20-50%) density of gaba axon terminals in the nucleus accumbens. |
1990-06-05 |
2023-08-11 |
rat |
| S D Glick, J N Carlso. Regional changes in brain dopamine and serotonin metabolism induced by conditioned circling in rats: effects of water deprivation, learning and individual differences in asymmetry. Brain research. vol 504. issue 2. 1990-02-06. PMID:2598025. |
after achieving criterion performance (100 full turns per hour) for at least 10 consecutive sessions, rats were sacrificed 20 min after starting a session and levels of dopamine, dopac (3,4-dihydroxyphenylacetic acid), serotonin, and 5-hiaa (5-hydroxyindoleacetic acid) were assayed in nigrostriatal (corpus striatum), mesolimbic (nucleus accumbens) and mesocortical (medial prefrontal cortex) brain regions. |
1990-02-06 |
2023-08-11 |
rat |
| A Gratton, B J Hoffer, G A Gerhard. In vivo electrochemical studies of monoamine release in the medial prefrontal cortex of the rat. Neuroscience. vol 29. issue 1. 1989-06-08. PMID:2710348. |
the magnitude of the reduction current measured following the oxidation reaction suggests a contribution of both serotonin and dopamine to the electrochemical signal, dopamine serving as the predominant monoamine in the medial prefrontal cortex proper and serotonin appearing to predominant in the more posterior regions of the frontal cortex. |
1989-06-08 |
2023-08-11 |
rat |
| A J MacLennan, M A Pelleymounter, S Atmadja, A Jakubovic, S F Maier, H C Fibige. D2 dopamine receptors in the rat prefrontal cortex: characterization and alteration by stress. Brain research. vol 477. issue 1-2. 1989-05-19. PMID:2522809. |
d2 dopamine (da) receptors were characterized in the medial prefrontal cortex (mpfc) of the rat by employing radioligand binding techniques which greatly reduced [3h]spiperone binding to filters, s2 serotonin receptors and spirodecanone sites. |
1989-05-19 |
2023-08-11 |
rat |
| A Kalsbeek, J P De Bruin, M G Feenstra, M A Matthijssen, H B Uyling. Neonatal thermal lesions of the mesolimbocortical dopaminergic projection decrease food-hoarding behavior. Brain research. vol 475. issue 1. 1989-02-28. PMID:3214729. |
hoarding scores showed a significant positive correlation with the measured dopamine content of the medial prefrontal cortex, and not with the serotonin content. |
1989-02-28 |
2023-08-11 |
rat |
| S G Speciale, J D Miller, B A McMillen, D C Germa. Activation of specific central dopamine pathways: locomotion and footshock. Brain research bulletin. vol 16. issue 1. 1986-05-05. PMID:3955388. |
monoamine concentrations (da, serotonin and their metabolites) were measured, using high pressure liquid chromatography, in the neostriatum, nucleus accumbens, and medial prefrontal cortex in rats that were either induced to walk forward in a motorized rotating wheel (two speeds) or were exposed to footshock stress (two shock intensities). |
1986-05-05 |
2023-08-11 |
rat |
| M Ramírez, F Alba, F Vives, F Mora, C Osori. Monoamines and self-stimulation of the medial prefrontal cortex in the rat. Revista espanola de fisiologia. vol 39. issue 4. 1984-05-30. PMID:6144147. |
the participation of noradrenaline (ne) and serotonine (5-ht) in self-stimulation (ss) of the medial prefrontal cortex (mpc) in the rat has been studied. |
1984-05-30 |
2023-08-12 |
rat |